Search clinical trials for: AML with Gene Mutations
Total 339335 results
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City of Hope Medical CenterNational Cancer Institute (NCI)SuspendedAcute Myeloid Leukemia | Myelodysplastic SyndromeUnited States
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Heinrich-Heine University, DuesseldorfCelgene Corporation; Koordinierungszentrum für Klinische Studien DüsseldorfActive, not recruitingMyelodysplastic Syndromes | Leukemia, Myeloid, Acute | Chronic Myelomonocytic Leukemia | IDH2 Gene Mutation | IDH2 R172 | IDH2 R140Germany
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Endeavor Biomedicines, Inc.Active, not recruitingSolid Tumors With PTCH1 Loss-of-function MutationsUnited States
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PfizerCompletedAcute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic SyndromeSpain, Canada, Austria, Czechia, France, Hungary, Italy, Japan, Mexico, Poland, United Kingdom
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University of Alabama at BirminghamNational Institutes of Health (NIH); Mereo BioPharmaCompletedEmphysema or COPD | Alpha-1 Antitrypsin Deficiency (AATD) | Pi*ZZ, Pi*SZ, Pi*Null, Another Rare Phenotype/Genotype Known to be Associated With Either Low or Functionally Impaired AAT Including F or I MutationsUnited States
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Aptose Biosciences Inc.Active, not recruitingAcute Myeloid Leukemia | Myelodysplastic SyndromesUnited States
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Stealth BioTherapeutics Inc.Active, not recruitingMitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Complex I Deficiency | Mitochondrial Pathology | Mitochondrial DNA Depletion | Mitochondrial DNA Mutation | Mitochondrial DNA Deletion | Mitochondrial Metabolism DefectSpain, United States, Italy, Netherlands, Australia, Germany, Hungary, New Zealand, Norway, United Kingdom
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Wake Forest University Health SciencesNational Cancer Institute (NCI)TerminatedLymphoma | Multiple Myeloma | Solid Tumor | Malignant Neoplasm | Mutation AbnormalityUnited States
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SCRI Development Innovations, LLCBristol-Myers SquibbWithdrawnMyelodysplastic Syndromes | Leukemia, Myeloid, Acute | Myelodysplastic Syndrome Acute Myeloid LeukemiaUnited States
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Arog Pharmaceuticals, Inc.CompletedAcute Myeloid Leukemia With FLT3 Activating Mutations That Has Relapsed or Been Refractory After One or More Prior TherapiesUnited States
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University of Campania "Luigi Vanvitelli"Retina Italia OnlusCompletedLeber Congenital Amaurosis 2 | Retinitis Pigmentosa 20Italy
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Sheba Medical CenterAstraZenecaSuspendedCarcinoma, Non-Small-Cell Lung | Genes, erbB-1Israel
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Incyte CorporationCompletedNon-Small Cell Lung Cancer (NSCLC)Spain, United States, Italy, Germany, France
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Forma Therapeutics, Inc.CompletedAcute Myeloid Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Acute Myelogenous LeukemiaUnited States
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Daiichi Sankyo, Inc.CompletedAcute Myeloid Leukemia | LeukemiaHong Kong, Canada, Belgium, France, Spain, Taiwan, United States, Australia, Czechia, Hungary, Italy, Israel, Japan, Korea, Republic of, Germany, China, Ukraine, Romania, Argentina, Croatia, Brazil, Serbia, Russian Federation, Portugal, Bulgari... and more
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Forma Therapeutics, Inc.CompletedCohort 1a and 1b: Glioma (Advanced Gliomas and Glioblastoma Multiforme) | Cohort 2a and 2b: Hepatobiliary Tumors (Hepatocellular Carcinoma, Bile Duct Carcinoma, Intrahepatic Cholangiocarcinoma, Other Hepatobiliary Carcinomas) | Cohort 3a and 3b: Chondrosarcoma | Cohort 4a and 4b: Intrahepatic... and other conditionsUnited States, Korea, Republic of, Australia, United Kingdom, Spain, France
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Seagen Inc.Active, not recruitingUrologic Neoplasms | Uterine Cervical Neoplasms | Uterine Neoplasms | Carcinoma, Non-Small-Cell Lung | Biliary Tract Neoplasms | HER2 Mutations Breast NeoplasmsUnited States, United Kingdom, Spain, Korea, Republic of, Italy, Belgium, Germany, Japan, Netherlands, Poland
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Ciceri FabioCompletedAcute Myeloid Leukemia | Myelodysplastic Syndromes | Transplant-Related Hematologic MalignancyItaly
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Radboud University Medical CenterCompletedMDC1A | SELENON-related MyopathyNetherlands
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Case Comprehensive Cancer CenterCompletedMetastatic or Unresectable MelanomaUnited States
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QuantumLeap Healthcare CollaborativeByondis B.V.WithdrawnOvarian Cancer | Metastatic Cancer | Metastatic Breast Cancer | Bladder Cancer | Triple Negative Breast Cancer | HER2-positive Breast Cancer | Gastroesophageal Adenocarcinoma | Ovarian Carcinoma | HER2-positive Gastric Cancer | Metastatic Gastrointestinal Carcinoid Tumor | HER2-positive Metastatic Breast... and other conditionsUnited States
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Case Comprehensive Cancer CenterActive, not recruitingMyelodysplastic Syndromes | Refractory Acute Myeloid Leukemia | Relapsed Acute Myelomonocytic LeukemiaUnited States
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Ohio State University Comprehensive Cancer CenterActive, not recruitingChronic Lymphocytic Leukemia | Ibrutinib ResistanceUnited States
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Masonic Cancer Center, University of MinnesotaCompletedMyelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML)United States
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Ossium Health, Inc.Center for International Blood and Marrow Transplant ResearchWithdrawnAcute Myeloid Leukemia | Myelodysplastic Syndromes | Acute Leukemia | Acute Lymphocytic Leukemia | T-lymphoblastic Lymphoma | Acute Undifferentiated Leukemia | Acute Biphenotypic Leukemia
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New York Medical CollegeCompletedMyelodysplastic Syndrome | Acute Myelogenous LeukemiaUnited States
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AbbVieRoche-GenentechActive, not recruitingAcute Myeloid Leukemia (AML)United States, Australia, Canada, China, Czechia, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Puerto Rico, Russian Federation, Spain, Taiwan, Turkey, United Kingdom
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Asan Medical CenterActive, not recruitingPatients With MDS, Acute Myeloid Leukemia (AML) Evolving From MDS, and Chronic Myelomonocytic Leukemia (CMML)Korea, Republic of
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NovartisTerminatedHypertensionUnited States, Denmark, Finland, Norway, Sweden
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Asan Medical CenterCompletedMyelodysplastic SyndromesKorea, Republic of
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Astellas Pharma Global Development, Inc.CompletedMyelodysplastic Syndrome | Acute Myeloid Leukemia (AML)United States, Japan
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Institut de Recherches Internationales ServierCelgene CorporationActive, not recruitingUntreated AML | Newly Diagnosed Acute Myeloid Leukemia (AML) | AML Arising From Myelodysplastic Syndrome (MDS) | AML Arising From Antecedent Hematologic Disorder (AHD) | AML Arising After Exposure to Genotoxic InjuryUnited States, Germany, Netherlands
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Taiho Oncology, Inc.TerminatedAdvanced or Metastatic Solid Tumors Irrespective of Gene Alterations | Advanced or Metastatic Solid Tumors With Germline PTEN Inactivating MutationsUnited States, United Kingdom, Austria, France
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Fondazione Policlinico Universitario Agostino Gemelli...Ministry of Health, ItalyTerminatedAcute Myeloid Leukemia | MyelodysplasiaItaly
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Race Oncology LtdAstex Pharmaceuticals, Inc.WithdrawnAcute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Higher Risk Myelodysplastic SyndromeAustralia
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Novartis PharmaceuticalsCompletedMyelodysplastic Syndromes | Bone Marrow Diseases | Hematologic Diseases | Leukemia | Leukemia, Myeloid | Leukemia, Myeloid, Acute | Preleukemia | Chronic Myelomonocytic LeukemiaUnited States, France, Australia, Netherlands, Spain, Germany, United Kingdom, Finland
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pharmaand GmbHTerminated
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Sarit AssoulineCompleted
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Bellicum PharmaceuticalsTerminatedAcute Myeloid Leukemia | Myelodysplastic SyndromesUnited States
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Federal Research Institute of Pediatric Hematology...Active, not recruitingMyelodysplastic Syndromes | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Myeloblastic Leukemia | Malignant Lymphoma | Biphenotypic Acute LeukemiaRussian Federation
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University of California, DavisNational Cancer Institute (NCI); Merck Sharp & Dohme LLC; NovartisActive, not recruitingKRAS Gene Mutation | Stage IV Non-Small Cell Lung Cancer AJCC v7 | Recurrent Non-Squamous Non-Small Cell Lung Carcinoma | Metastatic Non-Squamous Non-Small Cell Lung CarcinomaUnited States
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University of NebraskaNational Cancer Institute (NCI); Spectrum Pharmaceuticals, IncCompletedPeripheral T-cell Lymphoma | Anaplastic Large Cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Hepatosplenic T-cell LymphomaUnited States
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Sameek RoychowdhuryActive, not recruitingCholangiocarcinoma | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Metastatic Malignant Solid NeoplasmUnited States
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Sameek RoychowdhuryActive, not recruiting
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Novartis PharmaceuticalsCompletedAdvanced Non-small Cell Lung CancerSpain, Canada, Germany, Korea, Republic of, Taiwan, United States, Japan, Netherlands, Singapore
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Alliance for Clinical Trials in OncologyNational Cancer Institute (NCI)Active, not recruiting
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Chang Gung Memorial HospitalCompletedAcute Myeloid LeukemiaTaiwan
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Jiangsu HengRui Medicine Co., Ltd.Completed
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University of LeipzigMillennium Pharmaceuticals, Inc.CompletedMyelodysplastic Syndromes | Minimal Residual Disease | Acute Myeloid Leukemia in RemissionGermany
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Vincerx Pharma, Inc.Active, not recruitingNeoplasmsUnited States, Chile, Spain