Search clinical trials for: Biomarker of Response

Total 431513 results

University of Michigan
Mayo Clinic; National Eye Institute (NEI); University of Nebraska

Completed

Glaucoma Biomarkers

Glaucoma | Healthy

United States
Johns Hopkins University

Completed

Scleral Response to Intraocular Pressure (IOP)

Glaucoma, Open-Angle
Massachusetts General Hospital
Dana-Farber Cancer Institute; Beth Israel Deaconess Medical Center; North Shore...

Completed

Platinum for Triple-Negative Metastatic Breast Cancer and Evaluation of p63/p73 as a Biomarker of Response

Breast Cancer

United States
GlaxoSmithKline

Completed

Study to Determine the Utility of Novel Technologies and Biomarkers to Measure Human Response to Rosiglitazone Maleate

Diabetes Mellitus, Type 2

United States
German Center for Neurodegenerative Diseases (DZNE)
University Hospital, Bonn

Unknown

Long-term Cognitive and Cerebral Changes in Sepsis Survivors and Their Predictors (BonSEP)

Severe Sepsis With Septic Shock | Severe Sepsis Without Septic Shock

Germany
Michael Chancellor, MD
William Beaumont Hospitals

Completed

Urinary Biomarkers For Objective Measurement Of InterStim® Response In Over Active Bladder (OAB) Patients.

Overactive Bladder

United States
Duke University

Completed

The MURDOCK Study Community Registry and Biorepository Multiple Sclerosis Cohort

Multiple Sclerosis

United States
Universitätsklinikum Hamburg-Eppendorf

Unknown

Neutrophil Extracellular Traps and Neonatal (PV4991) & Pediatric Sepsis (PV5063)

Sepsis

Germany
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Proteomic Profiling in Predicting Response in Patients Receiving Erlotinib for Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer

Lung Cancer

United States
National Cancer Institute (NCI)

Terminated

Birinapant for Advanced Ovarian, Fallopian Tube, and Peritoneal Cancer

Fallopian Tube Neoplasms | Peritoneal Neoplasms | Epithelial Ovarian Cancer

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Institute of Allergy and Infectious...

Completed

Immune Response After Stem Cell Transplant in HIV-Positive Patients With Hematologic Cancer

HIV Infection | Hematopoietic and Lymphoid Cell Neoplasm

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Completed

Biomarkers of Response in Blood and Tumor Tissue Samples From Patients With Unresectable Stage IV Squamous Cell Cancer of the Head and Neck Previously Treated With Cetuximab, Cisplatin, and Radiation Therapy

Head and Neck Cancer
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Completed

Biomarkers in Predicting Response to Rituximab Treatment in Samples From Patients With Indolent Follicular Lymphoma

Lymphoma
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

DNA Analysis in Influencing Response to Rituximab in Samples From Patients With Follicular Lymphoma Treated on ECOG-E4402

Lymphoma
National Taiwan University Hospital

Unknown

Evaluation of Treatment Response With Integrated MRI/PET in Patients With Hepatocellular Carcinoma

Hepatocellular Carcinoma

Taiwan
Stanford University
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Tissue-specific Responses to Influenza Immunization and Their Relation to Blood Biomarkers (SLVP032)

Influenza
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Quantitative Imaging Biomarkers of Treatment Response in Osteosarcoma and Ewing Sarcoma

Osteosarcoma | Ewing Sarcoma | Paget's Disease

United States
Beth Israel Deaconess Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Endothelium in Severe Sepsis

Sepsis | Septic Shock | Severe Sepsis

United States
Fundación para la Investigación del Hospital Clínico...

Completed

Clinical and Biomarker Study of the Efficacy of Extracorporeal Photopheresis in Graft-versus-host Disease (BIOECP_GVHD)

Graft-versus-host Disease
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

3T MRI Biomarkers of Glioma Treatment Response

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Hoffmann-La Roche

Completed

A Study to Assess Biomarkers Impact on Participants Response to Erlotinib Treatment for First-line Non-Small Cell Lung Cancer With Endothelial Growth Factor Receptor (EGFR) Activating Mutations (BIOTEC)

Carcinoma，Non-Small-Cell Lung

Romania
Air Force Military Medical University, China

Unknown

Biomarkers and Functional Imaging in Predicting Response of Esophageal Cancer

Esophageal Cancer

China
University of Ulm

Completed

NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock (NICUPS)

Sepsis | Shock | Critically Ill | SIRS | Multiple Organ Dysfunction Syndrome

Germany
University of Washington
National Cancer Institute (NCI)

Completed

PET Scans in Assessing Response To Treatment in Patients Receiving Hormone Therapy or Trastuzumab for Breast Cancer

Breast Cancer

United States
Royal Marsden NHS Foundation Trust

Completed

PROSPECT-C: A Study of Biomarkers of Response or Resistance to Anti-EGFR Therapies in Metastatic Colorectal Cancer (PROSPECT-C)

Metastatic Colorectal Cancer

United Kingdom
Washington University School of Medicine

Terminated

Gene Expression and FDG PET/MRI in Evaluating Treatment Response in Patients With Locally Advanced Rectal Cancer Undergoing Chemotherapy and Radiation Therapy Before Surgery

Rectal Neoplasms

United States
National Cancer Institute (NCI)

Completed

MK2206 and Erlotinib Hydrochloride in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Progressed After Previous Response to Erlotinib Hydrochloride Therapy

Lung Adenocarcinoma | Recurrent Non-Small Cell Lung Carcinoma | Adenosquamous Lung Carcinoma | Bronchioloalveolar Carcinoma | Large Cell Lung Carcinoma | Squamous Cell Lung Carcinoma

United States
CR-CSSS Champlain-Charles-Le Moyne
Sanofi; Regeneron Pharmaceuticals; Quebec Clinical Research Organization in Cancer

Terminated

Study to Identify Biomarkers of Clinical Response to Aflibercept in Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

Canada
Hoffmann-La Roche

Completed

A Study to Measure Serum Periostin, Asthma-Related Biomarkers and Response to Prednisolone in Adult and Adolescent Patients With Severe Oral Corticosteroid-Dependent Asthma

Asthma

United Kingdom
University of Washington
National Cancer Institute (NCI)

Withdrawn

Carbon-11 Acetate and Fluorine F 18 Sodium Fluoride PET as a Biomarker of Treatment Response in Patients With Hormone Resistant Metastatic Prostate Cancer

Recurrent Prostate Cancer | Hormone-resistant Prostate Cancer | Stage IV Prostate Cancer

United States
Conselho Nacional de Desenvolvimento Científico...

Completed

Hemodynamic Changes After Anesthesia With Propofol: Study of Biomarkers

Hemodynamic Responses to Propofol
Central Hospital, Nancy, France

Unknown

Study of Polyfunctionality of Anti-tumor T Lymphocytes in Cancerology: Potential Biomarker for Emerging Immunotherapies (POLYTCANCER)

Cancer
Maria Stoenoiu

Unknown

Ultrasound as Imaging Biomarker of Early Response to Tocilizumab and Methotrexate in Very Early Rheumatoid Arthritis (TOVERA)

Rheumatoid Arthritis

Belgium
Medical University of Warsaw

Unknown

Inflammatory Response as a Prognostic Factor of Recurrence of Atrial Fibrillation After Ablation (ACtIVE-AF)

Atrial Fibrillation

Poland
Merck Sharp & Dohme LLC

Completed

A Clinical Study to Determine Biomarkers of Response to a Gamma Secretase Inhibitor

Healthy
Hospices Civils de Lyon

Unknown

Evaluation of Immunosuppression in Septic Shock: Biomarkers and Pharmacological Restoration (IMMUNOSEPSIS) (IMMUNOSEPSIS)

Immunology of Septic Shock

France
University Hospital, Basel, Switzerland
University of Basel; Aarelab AG

Completed

Vitamin B12 Acceptance and Biomarker Response Study

Vitamin B 12 Deficiency

Switzerland
University of Utah

Withdrawn

A Biomarker Study to Identify Predictive Signatures of Response to LDE225 (Hedgehog Inhibitor) In Patients With Resectable Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Predicting Response to Treatment in Bone Marrow Samples From Young Patients With Acute Myeloid Leukemia

Leukemia
Tongji Hospital

Unknown

Asthma Biomarkers for Predicting Response to Therapy

Asthma

China
Pfizer

Completed

The Dose Response of Prednisone on Biochemical and Clinical Makers in Adult Healthy Volunteers

Healthy Adults

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Radboud University Medical Center; UMC Utrecht; Philips Healthcare; Immunexpress; Center for Translational Molecular Medicine and other collaborators

Unknown

Molecular Diagnosis and Risk Stratification of Sepsis (MARS)

Sepsis

Netherlands
MeMed Diagnostics Ltd.

Completed

Observational, Prospective Clinical Study to Evaluate Biomarkers as Indicators of Acute Bacterial or Viral Infections (CURIOSITY)

Gastroenteritis | UTI | LRTI | Fever Without Source | Systemic Infections/Bacteremia/Meningitis

Israel
Federal University of Minas Gerais
Fundação de Amparo à Pesquisa do estado de Minas Gerais

Completed

Use of Inflammatory Biomarkers to Guide Antibiotic Therapy in Patients With Severe Infections

Septic Shock | Severe Sepsis

Brazil
University of Arkansas

Completed

MR Imaging Biomarkers of Disease Response to ECT (Electroconvulsive Therapy) in Depression

Depression

United States
Amsterdam UMC, location VUmc
UMC Utrecht; Dijklander Ziekenhuis; Medical Center Haaglanden; Elisabeth-TweeSteden... and other collaborators

Completed

Safety and Efficacy of Procalcitonin Guided Antibiotic Therapy in Adult Intensive Care Units (ICU's) (SAPS)

Sepsis | Septic Shock | Severe Sepsis

Netherlands
Novartis Pharmaceuticals

Completed

Multiple-dose Regimen Study to Assess Effect of 12 Months of Secukinumab Treatment on Skin Response and Biomarkers in Psoriasis Patients

Psoriasis, Plaque-type Psoriasis

United States
Samsung Medical Center

Unknown

Effects of Antidepressant on Postsynaptic Signal Transduction in Serotonergic System of Depressed Patients

Depression

Korea, Republic of
Samsung Medical Center

Unknown

Prediction of Antidepressant Response Using Pharmacogenetics and Peripheral Lymphocytic Phenotype

Depression

Korea, Republic of
University of Ulm
German Research Foundation

Completed

Inflammatory Response After Muscle and Skeleton Trauma (IRAMST)

Multiple Trauma

Germany

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