Search clinical trials for: Drug absorption profile

Total 262705 results

Tecnoquimicas

Completed

Exploratory Pilot Study to Evaluate the Pharmacokinetic Profile of Magaldrate

Healthy

Brazil
TJ Biopharma Co., Ltd.

Terminated

A Study to Evaluate the Safety, Tolerability, and PK Profile of Single and Multiple Doses TJ202 in Patient With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE)

China
Vanderbilt University Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Nutrient Sensing in the Duodenum

The Effect of LCFA on Nutrient Absorption

United States
Recep Tayyip Erdogan University

Completed

The Effect of White Tea Consumption on Obesity

Obesity | Obesity Adult Onset | Obesity; Endocrine

Turkey
M.D. Anderson Cancer Center
Takeda

Active, not recruiting

Daratumumab, Bortezomib, and Dexamethasone Followed by Daratumumab, Ixazomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies

Carcinoma, Non-Small-Cell Lung | Carcinoma, Small Cell Lung | Carcinoma, Thymic

United States
pfm medical gmbh

Completed

Post-market Clinical Follow-up of Pfmmedical Ports

Patient Satisfaction | Vascular Access Port

Germany
State University of New York College of Optometry

Completed

Peripheral Defocus Profile of Multifocal Minus Contact Lenses

Refractive Errors | Myopia | Contact Lens

United States
Rahul Aggarwal
Xynomic Pharmaceuticals, Inc.

Completed

Abexinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumor Malignancies

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Metastatic Melanoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Locally Advanced Melanoma | Metastatic Malignant Solid Neoplasm | Metastatic Urothelial... and other conditions

United States
Luye Pharma Group Ltd.

Completed

Study to Evaluate the PK Profiles of LY03010 in Patients With Schizophrenia or Schizoaffective Disorder

Mental Disorders | Psychotic Disorders | Mood Disorders | Schizophrenia | Schizophrenia Spectrum and Other Psychotic Disorders | Molecular Mechanisms of Pharmacological Action | Tranquilizing Agents | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents | Neurotransmitter Agents | Central...

United States
James J. Peters Veterans Affairs Medical Center
Kessler Institute for Rehabilitation

Terminated

The Efficacy of Denosumab in Incomplete Patients Spinal Cord Injury

Spinal Cord Injury | Secondary Osteoporosis

United States
Bayer

Completed

A Study to Learn More About How a Smartphone App Called MyIUS Predicts Future Menstrual Bleeding in Women After They Have Begun Using Intrauterine Birth Control Method (a Birth Control Device is Inserted Into a Woman's Uterus by Her Doctor) (MyIUS)

Uterine Bleeding Profile Prediction

Spain, Germany, Sweden, Mexico, Brazil, Denmark
University Health Network, Toronto
Princess Margaret Hospital, Canada

Active, not recruiting

Selection Pressure and Evolution Induced by Immune Checkpoint Inhibitors and Other Immunologic Therapies (SPECIAL)

Melanoma | Head and Neck Cancer

Canada
University Health Network, Toronto

Active, not recruiting

Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy (MASST)

Cancer | Metastatic Cancer | Squamous Cell Carcinoma of the Head and Neck | Anal Canal Squamous Cell Carcinoma | Esophagus Squamous Cell Carcinoma

Canada
Washington University School of Medicine
National Cancer Institute (NCI); Incyte Corporation; American Society of Hematology

Active, not recruiting

Study of Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Myelodysplastic Syndromes | Hodgkin Disease | Non-Hodgkin Lymphoma | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia

United States
University Hospital Tuebingen

Terminated

Safety and Drug Absorption of Orally Administered Oleylphosphocholine (OlPC) in Healthy Adults

Leishmaniasis

Germany
Eli Lilly and Company

Completed

A Study of Insulin Efsitora Alfa (LY3209590) as a Weekly Basal Insulin Compared to Insulin Glargine in Adult Participants With Type 2 Diabetes on Multiple Daily Injections (QWINT-4)

Type 2 Diabetes | Type 2 Diabetes Treated With Insulin

United States, Germany, Mexico, Argentina, Puerto Rico, Italy, Spain, India
Primus Pharmaceuticals
Prosoft Clinical

Terminated

Assess the Potential for Adrenal Suppression and Systemic Drug Absorption Following Multiple Dosing With DFD-06

Psoriasis

United States
Chelsea and Westminster NHS Foundation Trust

Completed

The Effect of Dolutegravir on Whole-body Insulin Sensitivity, Lipid and Endocrine Profile in Healthy Volunteers (DTG Clamp)

HIV-1-infection on Healthy Volunteers

United Kingdom
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Using Advanced Imaging Studies to Develop a Profile of High-grade Serous Ovarian Cancer

Ovarian Cancer | High Grade Ovarian Serous

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Effect of Cabozantinib S-Malate or Lenvatinib Mesylate on Weight and Body Composition in Patients With Metastatic Endocrine Cancer

Thyroid Gland Medullary Carcinoma | Differentiated Thyroid Gland Carcinoma | Malignant Adrenal Gland Pheochromocytoma | Malignant Paraganglioma

United States
Cornell University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Active, not recruiting

Ethnic Differences in Iron Absorption (FeGenes) (FeGenes)

Iron Overload | Anemia, Iron Deficiency

United States
Sohag University

Enrolling by invitation

Comparison Between Early-onset and Late-onset Patients With Systemic Lupus Erythematosus.

Systemic Lupus Erythematosus

Egypt
James J. Peters Veterans Affairs Medical Center
Kessler Institute for Rehabilitation

Active, not recruiting

Treatment With Romosozumab Versus Denosumab to Improve Bone Mineral Density and Architecture in Subacute SCI

Osteoporosis | Spinal Cord Injuries

United States
Christian Hvas

Completed

Absorption of Peptides, Fluid, and Electrolytes in Patients With an Ileostomy (ABSOLYT)

Short Bowel Syndrome | Nutritional Deficiency | Ileostomy; Functional Disturbance | Absorption; Disorder, Protein

Denmark
University Hospital, Montpellier
Ferring Pharmaceuticals; IBSA Institut Biochimique SA

Completed

Sexual Intercourse and Vaginal Absorption of Progesterone (SexVAP)

Infertility

France
Jonsson Comprehensive Cancer Center
Genentech, Inc.

Completed

Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma

Glioblastoma | Gliosarcoma | Giant Cell Glioblastoma

United States
University of British Columbia
Canadian Institutes of Health Research (CIHR); University of Calgary; Alberta... and other collaborators

Completed

CIRN Pneumococcal Conjugate Vaccine 1 vs. 2 Dose Priming Study

Streptococcus Pneumoniae Infection | Invasive Pneumococcal Disease, Protection Against

Canada
CAO Group, Inc.
Sao Paulo State University, School of Dentistry at Aracatuba, Sao Paulo,...

Completed

Histopathological Evaluation of the Periodontal Ligament Subjected to Laser Ablation.

Pulp Necroses

Brazil
University of Washington

Completed

Comparison of Glargine to Degludec Insulin Transition With or Without a Bridging Glargine Dose (GLIDING)

Type 1 Diabetes

United States
CRG UZ Brussel
Merck KGaA, Darmstadt, Germany

Withdrawn

Effect of LH Supplementation on the Endometrial Gene Expression Profile in Poor Ovarian Responders

Poor Response to Ovulation Induction
Mabscale, LLC

Active, not recruiting

Study, Evaluating Pharmacokinetics, Immunogenicity and Safety Profiles of Pertuzumab Compared to Perjeta® in Healthy Man

Healthy Men

Russian Federation
University of Coimbra
Fundação para a Ciência e a Tecnologia

Completed

Concurrent Training and Metabolic Profile, Lung Function, Quality of Life and Stress

Quality of Life | Sedentary Lifestyle | Stress | Metabolic Disorders | Lung Function Decreased | Office Worker | Concurrent Exercise

Portugal
Ophthotech Corporation

Completed

A Phase 1 Ascending and Parallel Group Trial to Establish the Safety, Tolerability and Pharmacokinetics Profile of Volociximab (Alpha 5 Beta 1 Integrin Antagonist) in Subjects With Neovascular Age- Related Macular Degeneration

Age-related Macular Degeneration
Ophthotech Corporation

Completed

A Phase 1, Safety, Tolerability and Pharmacokinetic Profile of Intravitreous Injections of E10030 (Anti-PDGF Pegylated Aptamer) in Subjects With Neovascular Age-Related Macular Degeneration

Age-related Macular Degeneration

United States
University of Memphis
Nature Fusions

Active, not recruiting

Pharmacokinetic Profile of N-Acetyl Cysteine

Pharmacokinetics

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Bone Loss in Melanoma Survivors Receiving Immunotherapy

Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Pathologic Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIA Cutaneous Melanoma... and other conditions

United States
Bionos Biotech S.L.

Active, not recruiting

Clinical Evaluation of the Magnesium Absorption Kinetics in Human Plasma Upon Oral Intake of Magnesium-based Products

Healthy Volunteers

Spain
Minia University Hospital

Completed

Use of Recombinant Factor VII as a Prophylactic Therapy for Adolescent Females With Heavy Menstrual Bleeding

Assessing the Bleeding Profile and the Quality of Life of the Enrolled Patients Before and 1 Year After Drug Intervention

Egypt
Yale University

Completed

The Effect of Bolus Speed of Rapid-Acting Insulin Analog Absorption and Action in Individuals With Type 1 Diabetes

Type1diabetes

United States
Emory University

Completed

Vitamin D and Prebiotics for Intestinal Health in Cystic Fibrosis

Cystic Fibrosis | Dysbiosis

United States
Clinica CES
Baxter Healthcare Corporation

Completed

RRT With a Cytokine Absorption Filter (oXiris ®) in Patients With Septic Shock

Septic Shock | Acute Kidney Injury

Colombia
King's College London

Completed

Pharmacokinetic Study of a Novel Lipid Formulation of Cannabidiol Compared to a Standard Formulation (CLIP)

Absorption; Chemicals

United Kingdom
University Hospital Muenster
Endo Health GmbH

Completed

Impact on Quality of Life of "Endo-App" (ELEA) (ELEA)

Quality of Life | Endometriosis | Endometriosis-related Pain

Germany
Institute of Cancer Research, United Kingdom

Active, not recruiting

The BARCODE 1 Study (Full Study): The Use of Genetic Profiling to Guide Prostate Cancer Targeted Screening. (BARCODE1)

Prostate Cancer

United Kingdom
National Institute of Environmental Health Sciences...

Completed

Prospective Natural History Study of Smoking, Immune Cell Profiles, Epigenetics and COVID-19

COVID-19

United States
Prisma Health-Midlands
Medical University of South Carolina

Enrolling by invitation

Temporal Profile of Serum Vitamin D Levels in Foot and Ankle Fusion Surgery

Ankle Arthrodesis | MTP Arthrodesis

United States
Medical University of South Carolina
National Institute on Minority Health and Health Disparities (NIMHD); Ralph...

Completed

Vitamin D Supplementation in RNA-seq Profiles of Single-core Prostate Samples, Among Veterans (VitD/RNA-seq)

Vitamin D Deficiency | Prostate Cancer | Stress Reaction

United States
Asan Medical Center

Completed

Comparison of Recovery Profiles Among Propofol, Remimazolam, and Dexmedetomidine After Intraoperative Sedation

Dexmedetomidine | Brachial Plexus Block | Orthopedic Procedures | Propofol | Remimazolam | Sedatives

Korea, Republic of
Aarhus University Hospital

Active, not recruiting

Residual Disease MEMory in PSOriasis Skin During EnstiLAR® and Narrow-band Ultraviolet B Therapy: The MEMPSOLAR Study (MEMPSOLAR)

Skin Diseases | Psoriasis | Skin Diseases, Papulosquamous | Psoriasis Vulgaris | Skin and Connective Tissue Diseases

Denmark

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