Search clinical trials for: Large-scale prospective trial

Total 46649 results

Mahidol University

Active, not recruiting

Comparison of Efficacy in Removal of Advanced Glycation End Products (AGEs) Between Super High-flux Hemodialysis and Postdilution Online Hemodiafiltration: A Single-center, Prospective, Open-label, Crossover Randomized Controlled Trial

End Stage Renal Disease

Thailand
Hospital Plató

Completed

HAL-RAR Versus Hemorrhoidectomy in the Treatment of Grade III-IV Hemorrhoids. Prospective, Randomized Trial

Pain, Postoperative | Hemorrhoids

Spain
Taejoon Pharmaceutical Co., Ltd.

Completed

A Prospective, Randomized, Investigator-blinded, Parallel, Multi-center, Phase 3 Trial (PROPELLER)

Bowel Preparation

Korea, Republic of
Spectrum Health Hospitals

Completed

The Transversus Abdominis Plane Block: A Prospective Randomized Clinical Trial Using EXPAREL.

Postoperative Pain

United States
GiMer Medical

Completed

A Prospective, Multi-site, Randomized, Sham-Controlled, Double-Blind Trial With One-Way Crossover Designed to Assess the Effectiveness and Safety of the Gimer NeuroBlock SCS Trialing System for the Treatment of Chronic Back Pain and/or Lower Limb Pain

Low Back Pain | Chronic Pain | Lower Limb Pain

Taiwan
NYU Langone Health

Completed

A Prospective Trial to Compare Deep Inspiratory Breath Hold (DIBH) With Prone Breast Irradiation

Breast Cancer
Eisai Limited

Completed

A Study to Investigate Dosage, Effectiveness, and Safety of Perampanel When Used as First Add-on Therapy in Participants >=12 Years With Partial Onset Seizures With or Without Secondary Generalization or With Primary Generalized Tonic-Clonic Seizures Associated With Idiopathic Generalized Epilepsy

Idiopathic Generalized Epilepsy | Partial Onset Seizures | Generalised Tonic-Clonic Seizures

France, Spain, Italy, Denmark, Germany, Portugal, Russian Federation
Deutsches Herzzentrum Muenchen
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

Prospective, Randomized Trial of Ticagrelor Versus Prasugrel in Patients With Acute Coronary Syndrome (ISAR-REACT 5)

Acute Coronary Syndrome (ACS)

Germany, Italy
Alejandro Reyes Sánchez

Completed

Clinical Trial Analyzing the Efficacy of Oral Administration of Tranexamic Acid in Spine Surgery.

Randomized Controlled Trial | Prospective Study | Tranexamic Acid (TXA) | Evidence-based Medicine

Mexico
Regina Elena Cancer Institute
Ministero della Salute, Italy

Completed

Open Versus Robot Assisted Radical Cystectomy With Totally Intracorporeal Urinary Diversion.

Bladder Cancer

Italy
University Hospital, Ghent

Completed

10 600 nm Ablative Fractional Laser Treatment of Scars: a Prospective Single Blinded Within Patient Controlled Randomized Trial

Scars After Surgical Intervention

Belgium
University Hospital, Ghent

Completed

Evaluation of Arthroscopic Reconstruction of the Anterior Cruciate Ligament by One Night Hospital Stay or by Day Surgery: a Randomised, Prospective Clinical Trial

Rupture of the Anterior Cruciate Ligament With Instability of the Knee Joint

Belgium
University Hospital, Ghent
European Venous Forum.; Benelux Society of Phlebology.

Completed

Prospective Multicentric Trial Between Radiofrequency Ablation With VNUS Closure Fast ® and Endovenous Ablation With 1470 nm Diode Laser and Tulip Fiber ® for Treatment of Primary Venous Insufficiency. (VNUS vs TULIP)

Chronic Venous Insufficiency C2 or Higher

Belgium
Centre hospitalier de l'Université de Montréal...
Maisonneuve-Rosemont Hospital

Withdrawn

Open-label Prospective Clinical Trial Evaluating the Safety and Efficacy of Biosynthetic CLP-PEG-MPC Corneal Implants in Patients Undergoing High-risk Deep Anterior Lamellar Keratoplasty. (CLP-PEG-MPC)

High-risk Corneal Transplantation | Corneal Blindess | Corneal Inflammation | Deep Anterior Lamellar Keratoplasty
Geisinger Clinic
National Cancer Institute (NCI)

Completed

Trial to Compare eConsent With Standard Consent Among Prospective Biobank Participants

Lynch Syndrome

United States
University Hospital, Ghent
Southern Implants, South Africa

Withdrawn

Mandibular Single Implant Overdenture: a Prospective Clinical Trial

Edentulous

Belgium
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Prospective Cohort for the Evaluation of Biomarkers Following HCT (BMT CTN 1202)

Allogeneic Hematopoietic Stem Cell Transplantation

United States
Eisai Co., Ltd.

Active, not recruiting

A Study of Equfina® on the Incidences of Adverse Drug Reactions in Participants With Parkinson's Disease (Including Participants With Hepatic Impairment)

Parkinson Disease

Japan
Rajavithi Hospital

Completed

Effect of Common Bile Duct Stone Clearance Using Saline Irrigation After Stone Removal: A Prospective Randomized Control Trial.

Common Bile Duct Calculi

Thailand
Uppsala University
Lund University

Completed

Antimicrobial Stewardship Interventions in a Hospital Setting

Infectious Disease

Sweden
Hendrik Streeck
Janssen, LP

Completed

Prospective Observational Cohort HIV & STI Study in Europe

HIV Infections | Sexual Behavior | HIV-1-infection | Risk Reduction

France, Hungary, Spain, Poland, Italy
Lomonosov Moscow State University Medical Research...

Completed

COLchicine Versus Ruxolitinib and Secukinumab in Open-label Prospective Randomized Trial in Patients With COVID-19 (COLORIT)

COVID 19

Russian Federation
University of Utah

Active, not recruiting

A Prospective Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves Versus Facet Joint Injection of Corticosteroid for the Treatment of Lumbar Facet Syndrome

Lumbar Facet Syndrome

United States
Centre hospitalier de l'Université de Montréal...
Canadian Institutes of Health Research (CIHR)

Completed

Coronary Artery Bypass Grafting Strategies for the Anterolateral Territory: a Prospective Randomized Clinical Trial (AMI-PONT)

Coronary Artery Disease

Canada
Virginia Commonwealth University

Terminated

Efficient Anterior Shoulder Ultrasound Reduction Multicenter Prospective Randomized Trial (EASiUR)

Shoulder Dislocation

United States
AstraZeneca

Completed

Prospective Multicentre Phase-IV Clinical Trial of Olaparib in Indian Patients With Ovarian and Metastatic Breast Cancer (SOLI)

Breast Cancer | Ovarian Cancer

India
ViiV Healthcare
Pfizer

Completed

Prospective Observational Epidemiologic Study of Maraviroc's Safety (POEM)

Human Immunodeficiency Virus

United States, Canada, Spain, Belgium, France, United Kingdom, Italy, Brazil, Puerto Rico, Germany, Greece
Assistance Publique - Hôpitaux de Paris

Completed

Multicenter, Prospective, Randomized, Controlled, Double-blind Trial on the Impact of Rosuvastatin on Subclinical Markers of Atherosclerosis in Patients With Primary Necrotizing Vasculitides (STATVAS)

ANCA-associated Primary Necrotizing Vasculitides

France
AOBiome LLC
Veristat, Inc.

Completed

A Prospective Study of B244 Delivered as a Topical Spray to Determine Safety and Efficacy in Subjects With Elevated Blood Pressure

Prehypertension | Hypertension, Stage I

United States
Sight Sciences, Inc.

Active, not recruiting

Prospective, Randomized, Masked, Controlled Trial To Evaluate The Safety And Effectiveness Of The TearCare® System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease (SAHARA)

Dry Eye | Meibomian Gland Dysfunction

United States
Oslo University Hospital

Completed

Prospective Trial for Examining Hematuria Using Computed Tomography (PROTEHCT)

Renal Cell Carcinoma | Urothelial Carcinoma | Renal Stone | Renal Cyst

Norway
Assaf-Harofeh Medical Center
Gama Healthcare Ltd.

Completed

The Impact of Bedside Wipes in Multi-patient Rooms: a Prospective, Crossover Trial Evaluating Infections and Survival

Hospital Acquired Infection

Israel
Ascension South East Michigan

Withdrawn

Use of Biodesign® Otologic Graft in Canal Wall Down Mastoidectomy: A Prospective, Randomized Trial

Otologic Disease

United States
Suzhou Zenith Vascular Scitech Co., Ltd.

Completed

A Prospective, Multi-center and Randomized Controlled Trial of Tianyi Revascularization Device in Acute Ischemic Stroke

Acute Ischemic Stroke | Large Vessel Occlusion | AIS | Thrombectomy

China
Taiwan Liposome Company

Completed

Extended and Controlled Release Liposomal Formulated Dexamethasone for Chronic Knee OA Pain (EXCELLENCE)

Osteoarthritis of the Knee

United States, Australia
Ganin Fertility Center

Completed

Strategies for Reducing Sperm DNA Fragmentation in ICSI Semen Samples: a Prospective Randomized Controlled Trial

Male Infertility

Egypt
Groupe d'Etude Therapeutique des Affections Inflammatoires...
Saint-Louis Hospital, Paris, France

Completed

A proSpective Randomized Controlled Trial comParing infliximAb-antimetabolites Combination Therapy to Anti-metabolites monotheRapy and Infliximab monothErapy in Crohn's Disease Patients in Sustained Steroid-free Remission on Combination Therapy (SPARE)

Crohn's Disease

Australia, Belgium, France
Stichting Hemato-Oncologie voor Volwassenen Nederland
Nordic CLL Study Group

Active, not recruiting

A Prospective, Multicenter, Phase-II Trial of Ibrutinib Plus Venetoclax in Patients With Creatinine Clearance >= 30 ml/Min Who Have Relapsed or Refractory Chronic Lymphocytic Leukemia (RR-CLL) With or Without TP53 Aberrations

Chronic Lymphocytic Leukemia in Relapse | Chronic Lymphocytic Leukemia in Remission

Netherlands, Belgium, Denmark, Finland, Norway, Sweden
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Canadian Blood Services

Active, not recruiting

An Innovative Trial Assessing Donor Sex on Recipient Mortality (iTADS)

Red Blood Cell Transfusion

Canada
South East Area Health Education Center, Wilmington...
New Hanover Regional Medical Center

Completed

Prospective Trial Comparing Two Different Polypropylene Meshes for Inguinal Hernias

Hernia, Inguinal

United States
Intelon Optics, Inc

Terminated

A Prospective Trial of the Intelon BOSS(TM) System

Lens Diseases | Cornea

United States
TearClear Corp

Active, not recruiting

Prospective, Double-masked, Randomized, Multi-center, Active-controlled, Parallel-group, 3-month Study Assessing the Safety & Ocular Hypotensive Efficacy of TC-002 Ophthalmic Solution Compared to Latanoprost Ophthalmic Solution 0.005% in Subjects With Elevated Intraocular Pressure (TC-002-301)

Elevated Intraocular Pressure

United States
AMAG Pharmaceuticals, Inc.
Registrat-Mapi

Completed

A Prospective, Noninterventional Follow-Up Study of Children Aged 23 to 25 Months, Born to Mothers Who Received Hydroxyprogesterone Caproate Injection, 250 mg/mL, or Vehicle for Prevention of Preterm Birth

Children Whose Mothers Received 17P and Those Who Received Vehicle in the 17P Efficacy Trial

United States, Spain, Russian Federation, Canada, Czechia, Hungary, Ukraine
University of Sao Paulo General Hospital

Completed

Analysis of TCLT in TBI Patients: a Prospective, Randomized Controlled Trial

Brain Injury | Cognitive Deficits

Brazil
RenJi Hospital
Beijing Viroad Biotechnology Co., Ltd.

Completed

CTC in Predicting Neoadjuvant Chemotherapy Among LABC Patients: a Single-center, Prospective, Exploratory Clinical Trial (CTCNeoBC)

Locally Advanced Breast Cancer | Circulating Tumor Cell

China
Ge Junbo
RainMed Medical

Completed

A Prospective, Multi-center Clinical Trial for Evaluating the Effectiveness and Safety of Online Coronary Angiography-Derived Index of Microcirculatory Resistance (caIMR) (Flash III)

Coronary Microvascular Dysfunction

China
Vanderbilt University Medical Center

Completed

A Comparison of Traditional and MOSES Laser Enucleation of the Prostate (MOLEP): A Prospective, Randomized, Double-blinded Control Trial A Comparison of Traditional and MOSES Laser Enucleation of the Prostate (MOLEP): A Prospective, Randomized, Double-blinded Control Trial

Benign Prostatic Hyperplasia

United States
Poitiers University Hospital

Withdrawn

Amoxicillin-clavulanate Alone or in Combination With Ciprofloxacin in Low-Risk Febrile Neutropenic Adult Patients: A Prospective, Double-blind, Randomized, Non-Inferiority Multicenter, Phase III Clinical Trial. (ACACIA)

Febrile Neutropenia
Yonsei University

Completed

Collagen-thrombin Matrix Efficacy During Cardiac Surgery: a Prospective Randomized Controlled Trial

Coronary Artery Disease

Korea, Republic of
Ankara City Hospital Bilkent

Completed

Effect of Yoga-based Exercises of Healthcare Workers During COVID-19 Pandemic: Prospective Clinical Trial

COVID-19 Pandemic | Yoga | Exercise Therapy | Muscle Stretching Exercises | Mind-Body Therapies

Turkey

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