Search clinical trials for: Muscarinic Antagonists

Total 32918 results

Pearl Therapeutics, Inc.

Completed

Pharmacokinetics and Safety Study of PT010 and PT003 in Healthy Chinese Adult Subjects

Chronic Obstructive Pulmonary Disease

China
Lena Nilsson

Completed

Patient-controlled Sedation With Propofol Versus Combined Sedation During Bronchoscopy

Sedation, Bronchoscopy
Novartis Pharmaceuticals

Completed

Comparing the Pharmacokinetics, Safety and Tolerability of NVA237 in Renal Impairment

Renal Impairment

Russian Federation
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Multiple Doses of QAX028 in Chronic Obstructive Pulmonary Disease (COPD) Patients

Chronic Obstructive Pulmonary Disease

United States
Pfizer

Completed

Open-label Long-term Extension Study of Fesoterodine in Japanese Subjects With Neurogenic Detrusor Overactivity.

Urinary Bladder, Neurogenic

Japan
Oregon Health and Science University
University of California, San Francisco; Stanford University

Active, not recruiting

Descemet Endothelial Thickness Comparison Trial (DETECT)

Keratoplasty | Grafting, Corneal | Transplantation, Corneal | Transplantation, Cornea | Keratoplasty, Lamellar

United States
Universitaire Ziekenhuizen KU Leuven

Completed

The DOMINO Trial: Diet Or Medication in Irritable Bowel syNdrOme (DOMINO)

Irritable Bowel Syndrome

Belgium
Emory University
National Institute of Mental Health (NIMH)

Completed

The ISLAND Study: InSuLa Assessed Needs for Depression (ISLAND)

Depression

United States
University of California, Berkeley

Completed

The Effects of Low Concentration Atropine on Pupil Size and Accommodation

Myopia

United States
Ataturk University

Completed

Combined Spinal Epidural Anesthesia in Obese Patients Undergoing Cesarean Surgery

Obesity | Pregnancy Related | Cesarean Section Complications | Hypotension | Spinal Anaesthetic Poisoning of Undetermined Intent

Turkey
GlaxoSmithKline

Completed

A Randomized Study, Comparing Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC /VI) Single Inhaler Triple Therapy, Versus Multiple Inhaler Therapy (Budesonide/Formoterol Plus Tiotropium) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States, Germany, Czechia
GlaxoSmithKline

Completed

A Randomized Study, Comparing Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Single Inhaler Triple Therapy, Versus Multiple Inhaler Therapy (Budesonide/Formoterol Plus Tiotropium) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, United States, Netherlands, Czechia
Daping Hospital and the Research Institute of Surgery...

Completed

Personalized Variable Versus Fixed Dose Glucocorticoid Therapy in AECOPD

Chronic Obstructive Pulmonary Disease

China
Avanir Pharmaceuticals

Terminated

Safety, Tolerability and Efficacy of AVP-786 for the Treatment of Disinhibition

Disinhibition Syndrome

United States
Karuna Therapeutics

Completed

A Study to Assess Safety and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-1)

Schizophrenia

United States
Bayer

Completed

Study to Gather Information About the Actual Use of an Adhesive Patch Placed on the Skin to Deliver Oxytrol Through the Skin Into the Bloodstream.

Overactive Bladder

United States
University Hospital, Geneva

Completed

Swiss PACK-CXL Multicenter Trial for the Treatment of Infectious Keratitis

Keratitis; Infectious Disease (Manifestation)

Switzerland
Federal University of São Paulo
Nacional Conseling of Scientific Development and Technology

Completed

Cocaine/Crack and Reduction of Compulsion With Biperiden

Cocaine Dependence

Brazil
Merck Sharp & Dohme LLC

Completed

Safety of Sugammadex for the Reversal of Neuromuscular Blockade in American Society of Anesthesiologists (ASA) Class 3 or 4 Participants (MK-8616-145)

Reversal of Neuromuscular Blockade

United States, Austria, Denmark, Germany
Weill Medical College of Cornell University
National Institute of Mental Health (NIMH)

Completed

Emotional and Cognitive Control in Late-Onset Depression

Depression

United States
Tanta University

Unknown

The Off Label Use of Glycopyrrolate in the Adults Intensive Care Unit.

Effect of Drugs

Saudi Arabia
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

Investigation of Sugammadex in Outpatient Urological Procedures

Bladder Cancer | Malignant Neoplasms of Urinary Tract

United States
Joy Schmitz
National Institute on Drug Abuse (NIDA)

Completed

Citalopram for Cocaine Dependence

Cocaine Dependence

United States
University of Kansas Medical Center

Terminated

Use of Hyoscyamine Versus Tamsulosin for Management of Ureteral Stent Irritation (HyTa Stent)

Lower Urinary Tract Symptoms

United States
Ache Laboratorios Farmaceuticos S.A.

Unknown

To Evaluate the Superiority of Fixed Combination (Orfenadrine 35mg, Acetaminophen 325mg, Caffeine 65mg and Diclofenac Sodium 50mg) Compared to Voltaren® (Diclofenac Sodium 50mg) in the Treatment of Acute Postural Low Back Pain. (Eiffel)

Postural Low Back Pain | Mechanical Low Back Pain
Jun Xiao
Qingdao Fifth People's Hospital

Completed

The Personalized Chinese Herb Formulas Over Hypertensive Bradyarrhythmia

Hypertensive Heart Disease

China
Sultan Qaboos University
Christian Medical College, Vellore, India

Unknown

Atropine 0.01% Eye Drops in Myopia Study (AIMS)

Myopia, Progressive

Oman
University of Texas Southwestern Medical Center

Completed

Chronotropic Incompetence in Patients With HFpEF

Heart Failure

United States
Augusta University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

SAT vs Escitalopram for Rectal Hypersensitivity

Rectal Hypersensitivity | Irritable Bowel Syndrome-Constipation

United States
University of Pennsylvania
Forest Laboratories

Completed

Brain Imaging and Treatment Studies of the Night Eating Syndrome (NES)

Night Eating Syndrome

United States
University of Nottingham
University College, London; Queen Mary University of London

Unknown

Reclassifying Constipation Using Imaging and Manometry (RECLAIM)

Constipation - Functional | Irritable Bowel Syndrome Characterized by Constipation

United Kingdom
Mahmoud Samy Abdallah

Completed

Role of Pentoxifylline as an Adjuvant Therapy for Adult Patients With Major Depressive Disorder

Major Depressive Disorder
Kokila N Thenuwara

Terminated

Minimizing Nausea and Vomiting During Spinals for CS

Nausea | Vomiting

United States
University of Texas Southwestern Medical Center
Merck Sharp & Dohme LLC

Completed

Sugammadex vs. Neostigmine for Neuromuscular Blockade Reversal in Thoracic Surgical Patients

Neuromuscular Blockade

United States
Western Galilee Hospital-Nahariya

Withdrawn

Patient Preferences, Analgesic Delivery Method and Pain Reduction in Spine Patients

Pain Relief
Swiss Federal Institute of Technology

Completed

The Effect of Lactoferrin and Dosing Regimen on Iron Absorption From a Maize-based Porridge in Kenyan Infants

Iron-deficiency

Kenya
Abramson Cancer Center of the University of Pennsylvania

Completed

A Study of Effects of Fesoterodine in Men at High Risk for Overactive Bladder/Detrusor Overactivity Post Robotic-Assisted Lap. Prostatectomy

Prostate Adenocarcinoma

United States
Astellas Pharma Singapore Pte. Ltd.

Completed

A Registry Study of Patients Initiating a Course of Drug Therapy for Overactive Bladder in Taiwan, Korea and China

Overactive Bladder (OAB)

Korea, Republic of, Taiwan
GlaxoSmithKline

Withdrawn

Legend: TRELEGY Real World Chronic Obstructive Pulmonary Disease (COPD) Effectiveness Study (LEGEND)

Pulmonary Disease, Chronic Obstructive

United States
Attikon Hospital

Completed

Sugammadex and Cognitive Function

Post Operative Cognitive Dysfunction

Greece
The V.P. Vyhodcev Eye Hospital

Unknown

Effectiveness of 0.01% Atropine Sulfate Solution in Controlling of Myopia Progression in Children

Myopia

Russian Federation
University of Pennsylvania
Washington University School of Medicine

Completed

Escitalopram Effects on CSF Amyloid Beta

Amyloid Beta Protein

United States
University of North Carolina, Chapel Hill
National Institute on Aging (NIA)

Completed

Understanding the Response to Fesoterodine Through Genetic Evaluation in the Elderly (URGE) (URGE)

Urge Urinary Incontinence

United States
Pusan National University Yangsan Hospital

Completed

Effect of Sugammadex vs. Neostigmine/Glycopyrrolate on Pediatric Emergence Delirium in Sevoflurane-rocuronium Anesthesia

Emergence Delirium

Korea, Republic of
Chiesi Farmaceutici S.p.A.

Completed

Functional Respiratory Imaging Study (FRI) (FRI)

Chronic Obstructive Pulmonary Disease

Belgium, Hungary
Assiut University

Completed

Hyoscine Butylbromide for Prevention of Bradycardia During Cesarean Section

Bradycardia | Cesarean Section Complications | Spinal Anesthetics Causing Adverse Effects in Therapeutic Use

Egypt
Astellas Pharma Global Development, Inc.

Completed

A Study to Evaluate Tolerability and Participants Preference Between Mirabegron and Tolterodine Extended Release (ER) in Participants With Overactive Bladder (OAB) (PREFER)

Overactive Bladder (OAB)

United States, Canada
GlaxoSmithKline

Completed

Study to Evaluate the Efficacy, Safety and Tolerability of Bupropion Hydrochloride Extended-release Tablet, and Escitalopram Oxalate Capsule in Subjects With Major Depressive Disorder

Depressive Disorder, Major

China
Medical College of Wisconsin

Completed

Dexmedetomidine and Propofol for Pediatric MRI Sedation

Headache | Neurofibromatoses | Abdominal Neoplasm | Tumor | Seizure Disorder | Hydrocephalus | Spine Deformity

United States
University of Alberta
Pfizer

Completed

A Study of Fesoterodine and Oxybutynin on Cognitive Function in Mild Cognitive Impairment

Overactive Bladder | Mild Cognitive Impairment

Canada

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