Search clinical trials for: Randomized single blind study

Total 133067 results

Beijing InnoCare Pharma Tech Co., Ltd.

Completed

A Phase I Randomized, Double-Blind, Placebo-Controlled, Parallel Group Clinical Study of ICP-332 in Healthy Subjects

Healthy Subjects

China
University Hospital, Clermont-Ferrand
Groupe Lépine

Completed

Comparison of the Use of Conventional Ancillary Reaming and Single-use Ancillary Reaming Material in Total Hip Replacement (LUUC)

Total Hip Replacement | Coxarthrosis

France
Shanghai Zhimeng Biopharma, Inc.

Completed

A Multiple-dose Study in Chinese Subjects to Evaluate Safety,Tolerability,PK and PD of ZM-H1505R

Hepatitis B, Chronic | Healthy Volunteers

China
UCB Pharma

Completed

Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures

Epilepsy

United States, Australia, Canada, Brazil, Mexico
UCB Pharma SA

Completed

Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures

Epilepsy

Belgium, Finland, France, Germany, Hungary, India, Italy, Netherlands, Poland, Spain, Switzerland, United Kingdom
Cali Pharmaceuticals LLC

Completed

A Phase 2, Randomized, Double-Blind, Dose Escalation Study in Postoperative Pain Open Inguinal Herniorrhaphy

Inguinal Herniorrhaphy

United States
National Taiwan University Hospital
China Medical University, Taiwan

Completed

Effect of Acupressure in Migraine: Single-blinded, Randomized, Controlled Clinical Trial

Migraine; Status

Taiwan
Florence Nightingale Hospital, Istanbul

Completed

Arthroscopic Rotator Cuff Repair Performed With Intraarticular Tranexamic Acid Could it Provide Improved Visual Clarity and Less Post-operative Pain? A Prospective, Double Blind, Randomized Study of 64 Patients.

Rotator Cuff Tears | Rotator Cuff Rupture | Tranexamic Acid | Shoulder Arthroscopy | Visual Clarity

Turkey
Istanbul University - Cerrahpasa (IUC)
Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Enrolling by invitation

Effects of Robot-assisted Arm Training on Respiratory Muscle Strength, Activities of Daily Living and Quality of Life in Stroke Patients: A Single-blinded Randomized Controlled Trial

Stroke

Turkey
University Hospitals Cleveland Medical Center

Terminated

Cerebral Oximetry in Single Lung Ventilation Thoracic Surgery

Hypoxia

United States
Tonix Pharmaceuticals, Inc.

Withdrawn

An Open-Label, Randomized Pilot Study Comparing the Safety of a Single Dose of TNX-1300 to Usual Care (UC) Alone for the Treatment of Signs and Symptoms of Acute Cocaine Intoxication in Male Emergency Department (ED) Subjects

Cocaine Intoxication

United States
Romark Laboratories L.C.

Completed

A Phase III, Randomized, Double-Blind, Placebo Controlled Trial to Evaluate the Efficacy and Safety of Nitazoxanide in the Treatment of Uncomplicated Influenza

Influenza

United States, Australia, Puerto Rico
Kindeva Drug Delivery

Completed

Single Blind Cross-over Dose Response Study in Subjects of Two Inhalers of Salmeterol and Fluticasone Propionate

Healthy

United Kingdom
Biocad

Completed

An International Multicenter, Randomized, Double-blind, Placebo-Controlled Clinical Study of Efficacy and Safety of Two Dosing Regimens of BCD-085 (JSC BIOCAD, Russia) in Patients With Moderate to Severe Plaque Psoriasis (BCD-085-7)

Moderate to Severe Plaque Psoriasis

Russian Federation
Boryung Pharmaceutical Co., Ltd

Completed

A Randomized, Double-blind, Active Control, Parallel Group, Titration, Multicenter Study to Evaluate the Efficacy and Safety of Fimasartan

Chronic Kidney Disease

Korea, Republic of
reMYND
NeuroScios GmbH

Completed

A Phase 1 (First in Human) Randomized, Double-blind, Placebo-controlled SAD, MAD Study With Oral REM0046127

Alzheimer Disease

Austria
Hospices Civils de Lyon

Completed

Surgical Treatment of Spinal Deformity With Sagittal Imbalance Using Patient-specific Rods: A Multicenter, Controlled, Double- Blind Randomized Trial: The PROFILE Study (PROFILE)

Spinal Deformity With Sagittal Imbalance
Shaare Zedek Medical Center

Completed

Symphysiolysis: Acupuncture Therapeutic Benefits: a Randomized Placebo Controlled Study.

Single Embryo Pregnancy | Gestational Weeks 24-42 | Pain/Sensitivity >5 on Numeric Rating Scale (NRS)

Israel
University Hospital, Strasbourg, France

Active, not recruiting

Personalized Non-invasive Neuromodulation by rTMS for Chronic and Treatment Resistant Catatonia (RETONIC)

Schizophreniform Catatonia | Treatment Resistant

France
ZimVie

Completed

A Study of Certain Prevail Implants Used for the Preservation of Crestal Bone in Short Fixed Bridge Cases. (Cliffhanger)

Partial Edentulism | Tooth Disease

United States
ZimVie

Completed

A Study of the Performance of Certain Prevail Implants Used in Short Fixed Cases (RadioCity)

Partial Edentulism | Tooth Disease

Germany
University Hospitals Cleveland Medical Center

Withdrawn

Intrapartum Epidural Fentanyl and Breastfeeding in the Immediate Postpartum Period: a Randomized, Controlled, Double-blinded Study

Neonatal Neurobehavior | Breastfeeding Outcomes

United States
Eurofarma Laboratorios S.A.

Withdrawn

A Parallel-group Active Comparator, Double-blind, Multicenter, Randomized, Double-blind, Phase III Clinical Study (SAVE)

Knee Osteoarthritis
Diffusion Pharmaceuticals Inc

Completed

Randomized, Double-Blind, Placebo-Controlled, Crossover Study of Trans Sodium Crocetinate in Healthy Volunteers Exercising at Altitude

Healthy Volunteers With Induced Hypoxia

United States
Prof. Dr. Matthias Preusser

Completed

A Single-blinded, Randomized, Placebo Controlled Phase II Trial of Prophylactic Treatment With Oral Azithromycin Versus Placebo in Cancer Patients Undergoing Antineoplastic Treatment During the Corona Virus Disease 19 (COVID-19) Pandemic

COVID

Austria
Vanderbilt University Medical Center

Completed

A Comparison of Traditional and MOSES Laser Enucleation of the Prostate (MOLEP): A Prospective, Randomized, Double-blinded Control Trial A Comparison of Traditional and MOSES Laser Enucleation of the Prostate (MOLEP): A Prospective, Randomized, Double-blinded Control Trial

Benign Prostatic Hyperplasia

United States
Genzyme, a Sanofi Company

Completed

Randomized Study of the Efficacy and Safety of a Single Dose of Synvisc-One® in Chinese Patients With Symptomatic Osteoarthritis of the Knee (C-SOUND)

Osteoarthritis

China
RedHill Biopharma Limited

Available

Expanded Access for the Treatment of Advanced Cholangiocarcinoma With ABC294640 (Yeliva ®)

Cholangiocarcinoma | Cholangiocarcinoma Non-resectable | Cholangiocarcinoma, Perihilar | Cholangiocarcinoma, Extrahepatic | Cholangiocarcinoma, Intrahepatic
USWM, LLC (dba US WorldMeds)

Suspended

Randomized, Double-Blind, Placebo-Controlled Pilot Study on the Safety and Effectiveness of LUCEMYRA During an Opioid Taper in Treatment of Withdrawal (TAPER)

Opioid Withdrawal (Disorder)

United States
Laboratoires FILLMED

Completed

Evaluation of the Efficacy and Safety of an Injectable Hyaluronic Acid-based Filler, Art Filler® Volume: Comparative Single-blind Study of the Non-inferiority Versus Juvéderm® Voluma on the Midface, Temple and Jaw-line and Non-comparative Study on the Chin. (AF3) (AF3)

Aging

France
University of Cadiz

Completed

Effectiveness of Percutaneous Electrolysis in the Treatment of Lateral Epicondylalgia. A Single-Blind Randomized Controlled Trial. (MRH)

Epicondylitis

Spain
University of Cadiz

Completed

Vacuum Myofascial Therapy Device and Physical Activity for the Treatment of Chronic Non-specific Low Back Pain. A Single Blind Randomized Clinical Trial

Chronic Nonspecific Low Back Pain

Spain
Nantes University Hospital

Active, not recruiting

Human Recombinant Interferon Gamma-1b for the Prevention of Hospital-acquired Pneumonia in Critically Ill Patients: a Double-blind, International, Phase 2, Randomized, Placebo-controlled Trial - the PREV-HAP Study (PREV-HAP)

Critically Ill Patients

France, Spain, Greece
University of Pennsylvania
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes... and other collaborators

Completed

A Randomized, Double-blind Placebo-Controlled Pharmacogenetic Study of Topiramate in European-American Heavy Drinkers (TOPG)

Alcoholism | Alcohol Use Disorder (AUD)

United States
NSABP Foundation Inc
Royal Marsden NHS Foundation Trust; Pfizer; Institute of Cancer Research, United...

Completed

A Phase II Randomized Study Evaluating the Biological and Clinical Effects of the Combination of Palbociclib With Letrozole as Neoadjuvant Therapy in Post-Menopausal Women With Estrogen-Receptor Positive Primary Breast Cancer (PALLET)

Breast Cancer | Breast Tumors | Breast Carcinoma

United Kingdom, United States, Canada
ASLAN Pharmaceuticals

Completed

A Multi-center, Randomized, Double-blind, Placebo-controlled, Multiple Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of Subcutaneously Delivered ASLAN004 in Adults With Moderate-Severe Atopic Dermatitis

Atopic Dermatitis

Australia, Singapore, United States
University of Sao Paulo General Hospital
Circa Scientific

Completed

Randomized Study on the Effect of Oesophageal Temperature on the Incidence of Esophageal Lesions After AF Ablation

Atrial Fibrillation | Cardiac Arrhythmias | Esophageal Ulcer

Brazil
AZ Sint-Lucas Gent

Completed

Virtual Reality for Pain Control During Extracorporeal Shock Wave Lithotripsy: a Prospective, Comparative, Randomized Study at a Single Institution

Stone Ureter | Stone, Kidney

Belgium
NGM Biopharmaceuticals, Inc

Completed

Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study In Subjects With Nonalcoholic Steatohepatitis and Stage 2/3 Fibrosis (ALPINE 2/3)

NASH - Nonalcoholic Steatohepatitis

United States, Puerto Rico
Eisai Co., Ltd.
FUJIFILM Toyama Chemical Co., Ltd.

Completed

A Multicenter, Randomized, Double-blind, Placebo-controlled Study of the Combination Therapy of T-614 and Methotrexate in Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate

Rheumatoid Arthritis

Japan
University of Memphis
Applied Food Sciences, Inc.

Completed

Impact of AMATEA™️ on Physiological Measures and Gaming Performance in Active Gamers: a Placebo Controlled, Double-blind, Randomized Study

Healthy

United States
Stanford University

Completed

Single-Blind Study of a Single Dose of Peginterferon Lambda-1a Compared With Placebo in Outpatients With Mild COVID-19 (COVID-Lambda)

COVID-19

United States
The Cooper Health System

Terminated

A Randomized, Double-Blind, Placebo-Controlled Study of Droxidopa for Fatigue in Parkinson's Disease

Fatigue | Parkinson Disease | Parkinsonism

United States
Theresa Zesiewicz, MD

Terminated

Blinded, Randomized Study of Gabapentin (Neurontin®) and Gabapentin Enacarbil (Horizant™) in Restless Leg Syndrome

Restless Leg Syndrome

United States
Chumakov Federal Scientific Center for Research...

Completed

This is a Double-blind, Placebo-controlled, Randomized Study of the Tolerability, Safety and Immunogenicity of an Inactivated Whole Virion Concentrated Purified Vaccine (CoviVac) Against Covid-19

Coronavirus Infections | Vaccine

Russian Federation
Bausch Health Americas, Inc.

Completed

A Phase 2, Multicenter, Randomized, Double-Blind, Vehicle Controlled, Parallel-Group, Clinical Study in the Treatment of Acne Vulgaris

Acne Vulgaris

United States, Canada
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Randomized, Double-Blind, Four-Arm Study Comparing Combination Nucleoside, Alternating Nucleoside, and Triple-Drug Therapy for the Treatment of Advanced HIV Disease (CD4 <= 50/mm3)

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Pfizer

Completed

A Randomized, Prospective, Double-Blind Study Comparing Fluconazole With Placebo for Primary and Secondary Prophylaxis of Mucosal Candidiasis in HIV-Infected Women

HIV Infections | Candidiasis | Candidiasis, Esophageal

United States
National Institute of Allergy and Infectious Diseases...
Washington University School of Medicine

Completed

A Randomized Double Blind Protocol Comparing Amphotericin B With Flucytosine to Amphotericin B Alone Followed by a Comparison of Fluconazole and Itraconazole in the Treatment of Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche; Glaxo Wellcome

Completed

A Randomized, Double Blind, Comparative Study of Dideoxycytidine (ddC) Alone or ddC/AZT Combination Versus Zidovudine (ZDV) Alone in Patients With HIV Infection Who Have Received Prior ZDV Therapy

HIV Infections

United States

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