Search clinical trials for: Single Patient Study

Total 208296 results

JIANG Zhi-Wei

Completed

Robotic Resection for Patients With Gastric Gastrointestinal Stromal Tumors: a Single-center Study

Gastrointestinal Stromal Tumor of Stomach

China
GlaxoSmithKline

Completed

Single Dose Safety Study for Compound to Treat Anemia in Patients With Renal Impairment

Kidney Disease

New Zealand
GlaxoSmithKline

Completed

A Clinical Study to Assess Single and Repeat Doses of a New Medication (GSK933776) in Patients With Alzheimer's Disease

Alzheimer's Disease

Australia, Sweden, Norway
GlaxoSmithKline

Completed

A First Time in Human Study to Assess GSK2336805 in Healthy Volunteers and Single Doses in Chronically Infected Hepatitis C Patients.

Hepatitis C

United States
St Stephens Aids Trust

Completed

A Phase IV, Open-label Single-arm Study Investigating the Pharmacokinetics and Pharmacodynamics of the Antiretroviral Combination of Rilpivirine and Ritonavirboosted Darunavir in Therapy-naive HIV-1 Infected Patients.

HIV

United Kingdom
Rothman Institute Orthopaedics

Unknown

A Prospective, Randomized, Comparative Study to Assess the Prevention of Surgical Site Infection (SSI's) in Revision Total Joint Arthroplasty Patients Treated With Single-Use Negative Pressure Wound Therapy (PICO) or Standard Care Dressings (AQUACEL Ag SURGICAL Dressing).

Surgical Incision

United States
GlaxoSmithKline

Completed

A Phase I/II, a Single Arm, Open-label Study of Ofatumumab (GSK1841157) in Patients With Previously Treated Chronic Lymphocytic Leukemia

Leukaemia, Lymphocytic, Chronic

Korea, Republic of, Japan
Transcend Medical, Inc.

Completed

Study of CyPass Implantation In Patients With Open Angle Glaucoma Refractory to Single or Multi-agent Topical Therapy (DUETTE)

Primary Open Angle Glaucoma (POAG)
University of California, Davis
National Institutes of Health (NIH)

Completed

Fish Oil to Prevent Asthma Exacerbations in Patients With ALOX5 Polymorphisms

Asthma

United States
Chinese Academy of Medical Sciences, Fuwai Hospital

Completed

A Single-center, Prospective,Randomized Study of Antiplatelet Effects of Ticagrelor Versus Clopidogrel in Patients With Dual Anti-platelet Therapy After Coronary Artery Bypass Grafting (ATCCC)

Antiplatelet Therapy of Coronary Artery Bypass

China
GlaxoSmithKline

Completed

A Study to Assess the Bronchodilator Effect of a Single Dose of Fluticasone Furoate (FF)/ Vilanterol (VI) 100/25 Micrograms (mcg) Combination When Administered in Adult Patients With Asthma

Asthma

New Zealand
Mannkind Corporation

Completed

Single Dose Clamp Study to Evaluate Concentration-time Profile and Metabolic Activity of 3 Dose Levels of Afrezza and 3 Dose Levels of Insulin Lispro in Patients With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Germany
McGill University Health Centre/Research Institute...

Terminated

Single Blind Randomized Study to Determine the Sensitivity and Specificity of 2 Non-invasive Markers of Early Coronary Disease

Coronary Artery Disease

Canada
Acorda Therapeutics

Completed

A Pharmacokinetic Study of a Single-Dose of Diazepam Nasal Spray in Adult Epileptic Patients Experiencing a Seizure Episode

Epilepsy

United States
Novartis Pharmaceuticals
International Maternal Pediatric Adolescent AIDS Clinical Trials Group; Southwest...

Terminated

Single-dose Study to Assess Efficacy of Canakinumab (ACZ885) in Patients With Active Juvenile Idiopathic Arthritis (SJIA) (β-SPECIFIC 1)

Systemic Juvenile Idiopathic Arthritis

United States, Argentina, Canada, Switzerland, Germany, United Kingdom, Israel, South Africa, Belgium, Greece, Italy, Spain, France, Brazil, Turkey, Hungary, Poland, Norway, Sweden, Netherlands, Peru, Denmark
GlaxoSmithKline

Completed

A Study To Investigate The Effect Of Inhaling A Single Dose Of GW642444M In COPD Patients.

Pulmonary Disease, Chronic Obstructive

Germany
Hoffmann-La Roche

Completed

A Study on the Effect of Vemurafenib on the Pharmacokinetics of a Single Dose of Tizanidine in Patients With BRAFV600 Mutation-Positive Metastatic Malignancies

Malignant Melanoma, Neoplasms

Korea, Republic of, Brazil, United States, Canada, Cyprus
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of a Single Dose of CNTO 136 (Sirukumab) on CYP450 Enzyme Activities After Subcutaneous Administration in Patients With Rheumatoid Arthritis

Arthritis, Rheumatoid

Germany, Korea, Republic of, South Africa, Moldova, Republic of
Novartis Pharmaceuticals
Bayer

Completed

Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Previously Treated Metastatic Colorectal Cancer

Colorectal Neoplasms | Rectal Neoplasms | Colonic Neoplasms

United States, Germany, Belgium, Canada, Spain, United Kingdom, Taiwan, France, Switzerland, Sweden, Portugal, New Zealand, Italy, Slovakia, Australia, Austria, Brazil, Hong Kong
Melinta Therapeutics, Inc.

Completed

Safety and Efficacy Study of Single-Dose Oral CEM-101 in Patients With Uncomplicated Urogenital Gonorrhea

Uncomplicated Urogenital Gonorrhea

United States
Helsinn Healthcare SA

Completed

Phase 2 Study Adding Pracinostat to a Hypomethylating Agent (HMA) in Patients With MDS Who Failed to Respond to Single Agent HMA (MEI-005)

Myelodysplastic Syndrome | MDS

United States
Galilee CBR

Unknown

Personalized Nutrition Prediction for Metabolic Syndrome Patients, an Open Single-center Study

Metabolic Syndrome
Novartis Pharmaceuticals

Terminated

A Single Center Study to Characterize the Absorption, Distribution, Metabolism and Excretion (ADME) of ASA404 After a Single Infusion in Patients With Solid Tumors

Advanced Solid Tumors

New Zealand
Medtronic Vascular
Medtronic

Terminated

Single-arm Study of Symplicity™ Renal Denervation System in Patients With Uncontrolled HyperTensioN in India (HTN-India)

Adults With Uncontrolled Hypertension

India
West Virginia University

Completed

Prospective Pilot Study of Bone Marrow and Peripheral Blood Samples From AML Patients to Characterize the Biologic Heterogeneity of the Disease Using Single Cell Network Profiling (SCNP)

Acute Myeloid Leukemia

United States
Hoffmann-La Roche

Completed

An Observational Study of MabThera/Rituxan (Rituximab) and Alternative TNF-Inhibitors in Patients With Rheumatoid Arthritis and an Inadequate Response to a Single Previous TNF-Inhibitor

Rheumatoid Arthritis

France, Germany, Colombia, Canada, Spain, United Kingdom, Greece, Italy, Mexico, Portugal, Norway, Monaco
Danone Research

Completed

A Single-centre, Randomised, Double-blind, Controlled, Parallel-group Study to Evaluate the Effect of a Fermented Dairy Product on Abdominal Distension, Digestive Symptoms and Rectal Sensitivity in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

Women With IBS-C

United Kingdom
AstraZeneca

Completed

A Study to Investigate How Common Pancreatic Exocrine Insufficiency (PEI) is in Patients With Type 2 Diabetes and Also to Investigate the Uptake of a Single Dose of EPANOVA® or OMACOR® in Patients With Different Degrees of PEI (PRECISE)

Diabetes Mellitus, Type 2 | Exocrine Pancreatic Insufficiency

Sweden, Poland, Latvia, Denmark, Hungary, Slovakia
Bayer

Completed

Single Dose Study in Patients With Chronic Obstructive Pulmonary Disease (COPD) Associated Pulmonary Hypertension.

Pulmonary Disease, Chronic Obstructive | Hypertension, Pulmonary

Germany
Nektar Therapeutics

Completed

A Study in Cancer Patients to Evaluate the Effect of a Single Dose of NKTR-102 (Etirinotecan Pegol) on the QTc Interval and to Assess Pharmacokinetics and Safety

Advanced Cancer | Metastatic Solid Tumors

United States
Uppsala University
AstraZeneca

Completed

A Single-dose Cross-over Study to Assess Direct and Indirect Effects of Dapagliflozin on Pancreatic Alpha and Beta Cells in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Sweden
Kyowa Kirin Co., Ltd.

Completed

A Single Dose Study of KHK6640 in Japanese Patients With Alzheimer's Disease.

Alzheimer's Disease

Japan
Tacere Therapeutics, Inc.

Completed

Safety and Efficacy Study of Single Doses of TT-034 in Patients With Chronic Hepatitis C

Hepatitis C

United States
AbbVie
Boehringer Ingelheim

Completed

Single Rising Dose Study of BI 655066 in Patients With Moderate and Severe Psoriasis

Psoriasis

United States, Germany, United Kingdom
Guangzhou Institute of Respiratory Disease

Unknown

A Clinical Trial on Effectiveness and Safety of Hydrogen Generator to Treat Dyspnea for the Patients With Tracheal Stenosis: A Randomized, Double-blind and Single-center Clinical Study

Tracheal Stenosis

China
Hospices Civils de Lyon

Completed

Causes of Death in Follicular Lymphoma: a Single Center Retrospective Analysis

This Study Describes the Different Causes of Death in 237 FL Patients

France
Sun Yat-sen University

Completed

Assessment of Hepatic Fibrosis by Shear Wave Elastography in Patients With Liver Malignancy: A Prospective Single-center Study

Hepatic Fibrosis | Liver Tumor
Hoffmann-La Roche

Completed

A Study of the Effect of Food on the Pharmacokinetics of Single Dose RO5185426 And the Safety And Efficacy of Continuous Administration in Patients With BRAF V600E Mutation-Positive Metastatic Melanoma

Malignant Melanoma

United States
Hoffmann-La Roche

Completed

A Single Ascending Dose Study of R1671 in Patients With Mild Intermittent Asymptomatic Asthma.

Asthma

United States
Hoffmann-La Roche

Completed

A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a Single Anti-TNF Inhibitor.

Rheumatoid Arthritis

Russian Federation
Hoffmann-La Roche

Completed

A Study of Single Doses of RO4998452 in Patients With Type 2 Diabetes

Diabetes Mellitus Type 2

France
Hoffmann-La Roche

Completed

A Study of RO6867461 Administered in Single- and Multiple-Ascending Doses in Patients With Wet Age-Related Macular Degeneration

Macular Degeneration

United States, United Kingdom
Genentech, Inc.

Completed

A Study of the Safety and Pharmacokinetics of MINT1526A, Administered Intravenously As a Single Agent and in Combination With Bevacizumab to Patients With Advanced Solid Tumors

Solid Cancers

United States
GlaxoSmithKline

Completed

Study to Assess GW642444 in Asthma Patients

Pulmonary Disease, Chronic Obstructive

Australia, New Zealand
Shanghai University of Traditional Chinese Medicine
Fudan University; Shanghai Chest Hospital

Completed

Clinical Study of Chemotherapy Combined With Chinese Medicine on Survival Affect of Elderly Patients With Lung Cancer

Cancer

China
Bristol-Myers Squibb
Medarex

Completed

A Single Arm Study of Ipilimumab Monotherapy in Patients With Previously Treated Unresectable Stage III or IV Melanoma

Melanoma

United States, Spain, Austria, Italy, Sweden, Russian Federation, Ukraine, Finland, Norway, Poland
Yonsei University

Withdrawn

A Prospective, Single-center, Randomized, Controlled, Open-label, Pilot Study to Compare the Effectiveness and Safety of DIuretics Add-On Strategy in Acute Decompensated Heart Failure Patients (DIOS II)

Congestive Heart Failure
Yale University

Terminated

Restoring Glutathione Synthesis With Tecfidera: An in Vivo H-MRS Single-Arm Study at 7T in Patients With RR MS

Multiple Sclerosis

United States
Sanofi

Withdrawn

A Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of a Single Dose of SAR438544 in Comparison to Glucagon in Type 1 Diabetes Mellitus Patients Under Induced Hypoglycemia

Type 1 Diabetes Mellitus
Oncoethix GmbH

Withdrawn

A Study Assessing tOTX015 in Combination With Azacitidine (AZA) or AZA Single Agent in Patients With Newly-diagnosed Acute Myeloid Leukemia (AML) Not Candidate for Standard Intensive Induction Therapy (SIIT)

Acute Myeloid Leukemia

3

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