Clinical Trials Sponsored by Astex Pharmaceuticals, Inc.

Total 4995 results

University of California, San Francisco
Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma

Not yet recruiting

Efficacy of Ra-223 in PSMA PET Optimally Selected Patients

Castration-Resistant Prostate Carcinoma | Metastatic Malignant Neoplasm in the Bone | Stage IVB Prostate Cancer AJCC v8

United States
Laminar Pharmaceuticals
Dana-Farber Cancer Institute; Hackensack Meridian Health; Laminar Pharma Inc

Recruiting

Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors

High-grade Glioma | Solid Tumor, Unspecified, Child

United States
Carsten Bindslev-Jensen
Novartis Pharmaceuticals; Thermo Fisher Scientific, Inc

Completed

Behandling af Boern Med Foedevareallergi Med Omalizumab (Xolair)

Food Allergy

Denmark
Memorial Sloan Kettering Cancer Center
Janssen Scientific Affairs, LLC; Xynomic Pharmaceuticals, Inc.

Active, not recruiting

Abexinostat and Ibrutinib in Diffuse Large B-cell Lymphoma and Mantle Cell Lymphoma

Mantle Cell Lymphoma | Diffuse Large B-cell Lymphoma

United States
European Organisation for Research and Treatment...
Tragara Pharmaceuticals, Inc.

Completed

Study of TG02 in Elderly Newly Diagnosed or Adult Relapsed Patients With Anaplastic Astrocytoma or Glioblastoma (STEAM)

Glioblastoma | Astrocytoma, Grade III

France, Austria, Germany, Netherlands, Switzerland
Spectrum Pharmaceuticals, Inc
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center

Completed

10-Propargyl-10-Deazaaminopterin in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma

Lymphoma

United States
University of California, Davis
National Cancer Institute (NCI); Genentech, Inc.; Aventis Pharmaceuticals

Completed

Docetaxel and Erlotinib in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors

Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
Fondazione Michelangelo
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; Millennium Pharmaceuticals...

Completed

Brentuximab Vedotin (SGN-35) as Salvage Treatment for CD30-positive Germ Cell Tumors

Germ Cell Cancer

Italy
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI); Aires Pharmaceuticals, Inc.

Completed

Inhaled Sodium Nitrite on Heart Failure With Preserved Ejection Fraction

Heart Failure

United States
Dana-Farber Cancer Institute
Beth Israel Deaconess Medical Center; Millennium Pharmaceuticals, Inc.

Completed

Study of the Combination of Bortezomib, Dexamethasone, and Rituximab in Patients With Waldenstroms Macroglobulinemia

Waldenstrom's Macroglobulinemia

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI); GlaxoSmithKline; Millennium Pharmaceuticals,...

Terminated

Ofatumumab and Bortezomib in Subjects With Relapsed CD20+Diffuse Large B Cell, Follicular, or Mantle Cell Lymphoma

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma

United States
Genzyme, a Sanofi Company
Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma

Completed

Subcutaneous Alemtuzumab (CAMPATH®, MabCampath®) in Relapsed/Refractory B-Cell Chronic Lymphocytic Leukemia

B-Cell Chronic Lymphocytic Leukemia (B-CLL)

United Kingdom, Belgium, France, United States, Czech Republic, Serbia
Stanford University
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

Indirect Magnetic Resonance Lymphangiography of the Head and Neck Region Using Conventional Gadolinium-based Contrast

Head and Neck Cancer | Head and Neck Cancers

United States
Guang'anmen Hospital of China Academy of Chinese...
Tasly Pharmaceuticals, Inc.

Completed

Trial of Tang-min-ling Pills in the Treatment of Type 2 Diabetes

Diabetes Mellitus, Type 2

China
Santalis Pharmaceuticals, Inc.
Derm Research, PLLC; ClinDatrix, Inc.; Clinical Trials of Texas, Inc.; Progressive... and other collaborators

Completed

A Trial of a Botanical Drug (EISO) for Treatment of Mild-to-Moderate Plaque Psoriasis

Plaque Psoriasis

United States
SFJ Pharmaceuticals X, LTD.
Merck KGaA, Darmstadt, Germany; AIO-Studien-gGmbH; Academic and Community Cancer... and other collaborators

Withdrawn

Study of Abituzumab in Combination With Cetuximab and FOLFIRI in Patients With Metastatic Colorectal Cancer. (AMELION)

Metastatic Colorectal Cancer
The Third Xiangya Hospital of Central South University
Livzon Pharmaceutical Group Inc.; Yung Shin Pharm. Ind. Co., Ltd.

Completed

The Efficacy and Safety of Ilaprazole/Doxycycline-based Bismuth-containing Quadruple Therapy on Hp Infected Duodenal Ulcers

Duodenal Ulcer Due to Helicobacter Pylori

China
Research in Real-Life Ltd
Teva Pharmaceuticals USA

Unknown

The Clinical Profile of UK Asthma Patients With Raised Blood Eosinophils

Asthma

United Kingdom
Research in Real-Life Ltd
Napp Pharmaceuticals Limited

Completed

A Guideline Approach to Therapy Step-down Utilising Flutiform Change and Step-down

Asthma

United Kingdom
Martha Sajatovic
Otsuka Pharmaceutical Development & Commercialization, Inc.

Completed

CAE Plus LAI in Individuals With Bipolar Disorder at Risk for Treatment Non-adherence (BD-CAEL)

Bipolar Disorder | Medication Adherence | Medication Non Adherence

United States
Otsuka Pharmaceutical Development & Commercialization...
H. Lundbeck A/S; PRA Health Sciences

Completed

A Trial of Single- and Multiple-doses of Aripiprazole in Adult Subjects With Schizophrenia or Bipolar I Disorder

Schizophrenia | Bipolar I Disorder

United States
Seung-Jung Park
Otsuka Pharmaceutical Development & Commercialization, Inc.

Terminated

Drug-Eluting Stenting Followed by Cilostazol tREAtment Reduces SErious Adverse Cardiac Events (DECREASE-PCI)

Coronary Artery Disease

Korea, Republic of
Teva Branded Pharmaceutical Products R&D, Inc.
United States Department of Defense

Withdrawn

Adenovirus Vaccine Pregnancy Registry

Adenovirus

United States
Teva Branded Pharmaceutical Products R&D, Inc.
Clalit Health Services; Rosetta Genomics

Completed

Cost-effectiveness Study of miRview™ Mets in Patients With Cancer of Unknown Primary (CUP)

Neoplasms, Unknown Primary

Israel
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study Comparing the Effectiveness and Safety of ULTRACET® (Tramadol HCl/Acetaminophen) Versus Placebo for the Treatment of Acute Pain From a Migraine Headache

Migraine | Headache | Head Pain
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Comparison of the Safety and Efficacy of Two Different Regimens of Levofloxacin in the Treatment of Acute Bacterial Sinusitis(Sinus Infection) in Adults.

Sinusitis
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Levofloxacin Compared With Ceftriaxone Sodium or Cefuroxime Axetil in the Treatment of Adults With Pneumonia

Pneumonia
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study Evaluating the Safety and Efficacy of Treating Sinus Infection With Levofloxacin 750 mg for 5 Days.

Maxillary Sinusitis
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Comparison of the Effectiveness and Safety of Levofloxacin to That of Ciprofloxacin in Treating Complicated Urinary Tract Infection and Acute Pyelonephritis.

Urinary Tract Infections | Pyelonephritis
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Cefuroxime Axetil in the Treatment of Adults With Persistent Bronchitis Experiencing Rapid Onset of Severe Worsening of Symptoms Caused by Bacteria

Bronchitis, Chronic
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Oral Ciprofloxacin in the Treatment of Adults With Uncomplicated Infections of the Skin and the Supportive Layers Beneath the Skin

Skin Diseases, Infectious
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Levofloxacin Compared With Lomefloxacin in the Treatment of Complicated Urinary Tract Infections

Urologic Diseases | Bacterial Infections | Bacteriuria | Urinary Tract Infections
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Levofloxacin Compared to Ticarcillin/Clavulanate Alone or Followed by Amoxicillin/Clavulanate in the Treatment of Complicated Skin Infections

Skin Diseases, Bacterial
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Oral Ciprofloxacin in the Treatment of Complicated Urinary Tract Infections

Urologic Diseases | Bacteriuria | Urinary Tract Infections | Pyelonephritis | Neurogenic Bladder
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Effectiveness and Safety of High Dose, Short-course Levofloxacin in the Treatment of Acute Bacterial Exacerbation (Worsening) of Chronic Bronchitis.

Bronchitis | Chronic Bronchitis
Massachusetts General Hospital
Dana-Farber Cancer Institute; Genentech, Inc.; Otsuka America Pharmaceutical

Completed

High Dose Chemotherapy and Stem Cell Transplant for Non-Hodgkin's Lymphoma or Central Nervous System (CNS) Lymphoma

Non-Hodgkin's Lymphoma | CNS Lymphoma

United States
Liquid I.V.
University of South Carolina; Nutrasource Pharmaceutical and Nutraceutical...

Completed

Clinical Trial to Evaluate the Effects of Two Novel Hydration Beverage Formulas on Rehydration in Healthy Adults

Dehydration | Cognitive Performance | Exercise Performance | Exercise Recovery | Fluid Balance | Rehydration

United States
Hong Kong Prospect Group Co. Limited
Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

Completed

A Study to Evaluate the Impact of a Nutritional Product on Cognition in Healthy Teenagers

Healthy

United States
Baylor College of Medicine
Eli Lilly and Company; TAP Pharmaceutical Products Inc.

Terminated

Growth Hormone and GnRH Agonist in Adolescents With Acquired Hypothyroidism

Hypothyroidism

United States
The Canadian College of Naturopathic Medicine
Wakunaga Pharmaceutical Co., Ltd.; Dicentra Inc.

Completed

Efficacy of a Multi-strain Probiotic in the Treatment of Irritable Bowel Syndrome (IBS)

Digestive System Diseases | Irritable Bowel Syndrome | Colonic Diseases, Functional | Colitis, Mucous | Colon, Irritable

Canada
Seoul National University Bundang Hospital
Daiichi Sankyo, Inc.; Daewoong Pharmaceutical Co. LTD.

Completed

Effects of Low Sodium Intake on the Anti-proteinuric Efficacy in Hypertensive Patient With Olmesartan (ESPECIAL)

Hypertension | Chronic Kidney Disease | Microalbuminuria

Korea, Republic of
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Levofloxacin Compared With Cefaclor in the Treatment of Adults With Chronic Bronchitis Experiencing Rapid Onset of Worsening of Symptoms Caused by Bacteria

Bronchitis | Bronchitis, Chronic
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Terminated

A Study of the Effectiveness and Safety of Tramadol HCl/Acetaminophen Compared to Placebo in Treating Acute Low Back Pain

Back Pain | Low Back Pain
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Comparison of the Effectiveness and Safety of ULTRACET® (Tramadol Hydrochloride/Acetaminophen) Versus ULTRAM® (Tramadol Hydrochloride) Versus Placebo in Patients With Pain After Oral Surgery

Pain, Postoperative | Surgery, Oral
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study to Evaluate the Safety and Effectiveness of Levofloxacin Compared With Ciprofloxacin in Patients With Chronic Bacterial Prostatitis

Prostatitis
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Oral Ciprofloxacin in the Treatment of Adults With Mild to Moderate Infections of the Skin and the Supportive Layers Beneath the Skin

Skin Diseases, Infectious | Cellulitis
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Efficacy and Safety of Tramadol HCl/Acetaminophen, Hydrocodone Bitartrate/Acetaminophen and Placebo in Patients With Pain From an Ankle Sprain With a Partial Torn Ligament

Pain | Sprains and Strains
Emily K. Sims
Juvenile Diabetes Research Foundation; Cancer Prevention Pharmaceuticals, Inc.

Recruiting

TArgeting Type 1 Diabetes Using POLyamines (TADPOL) (TADPOL)

Type 1 Diabetes

United States
The University of Texas Health Science Center at...
Abfero Pharmaceuticals, Inc

Suspended

Safety of SP-420 in the Treatment of Transfusional Iron Overload

Iron Overload

United States
Jason J. Luke, MD
Bristol-Myers Squibb; Agios Pharmaceuticals, Inc.

Completed

Ivosidenib (AG-120) With Nivolumab in IDH1 Mutant Tumors

Glioma | Advanced Solid Tumor | IDH1 Mutation

United States

Clinical Trials Sponsored by Astex Pharmaceuticals, Inc.

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