Clinical Trials Sponsored by Avillion LLP

Total 10226 results

Bond Avillion 2 Development LP
Avillion LLP

Completed

A Phase 2b Study of the Efficacy, Safety, and Tolerability of M1095 (Sonelokimab) in Subjects With Moderate to Severe Psoriasis

Psoriasis

United States, Germany, Bulgaria, Canada, Czechia, Hungary, Poland
Bond Avillion 2 Development LP

Completed

A Study to Assess the Efficacy and Safety of Budesonide/Albuterol Metered Dose Inhaler (BDA MDI/PT027) Used 4 Times Daily in Adults and Children 4 Years of Age or Older With Asthma (DENALI)

Asthma

United States, Germany, Ukraine, Serbia, Czechia, Argentina, Slovakia
Bond Avillion 2 Development LP

Completed

A Study to Assess the Efficacy of Budesonide/Albuterol Metered-dose Inhaler (BDA MDI/PT027) on Exercise-induced Bronchoconstriction in Adults and Adolescents With Asthma (TYREE)

Exercise Induced Bronchospasm

United States
Bond Avillion 2 Development LP

Completed

A Study to Assess the Efficacy and Safety of Budesonide/Albuterol Metered-dose Inhaler (BDA MDI/PT027) in Adults and Children 4 Years of Age or Older With Asthma (MANDALA)

Asthma

United States, Canada, Germany, Spain, South Africa, United Kingdom, Slovakia, Argentina, Ukraine, Serbia, Czechia
Bond Avillion 2 Development LP

Completed

To Compare the Pharmacokinetics of Budesonide Delivered by BDA MDI to Budesonide Delivered by Pulmicort Respules in Children With Asthma Aged 4 to 8 Years. (BLANC)

Asthma

United States
Bond Avillion 2 Development LP
Parexel

Active, not recruiting

A Comparison of PT027 vs PT007 Used as Needed in Participants With Asthma

Asthma

United States
AQILION AB

Completed

SAD, MAD and Food Effect Evaluation of Safety, Tolerability, and PK of AQ280 in Healthy Subjects

Eosinophilic Esophagitis (EoE)

United Kingdom
Avellino Labs USA, Inc.

Unknown

Study of the Prevalence of TGFBI Corneal Dystrophies

Corneal Dystrophy
University of Surrey
UK Civil Aviation Authority; Irish Civil Aviation Authority; Austrian Civil Aviation...

Suspended

Use of Dexcom G6 in Commercial Pilots With Insulin Treated Diabetes (DEXFLY)

Type 1 Diabetes

Austria, Ireland, United Kingdom
The Medical Pavilion Bahamas

Not yet recruiting

Allogeneic Cord Blood for Neurological Diseases in Adults

Stroke | Neurological Diseases | Spinal Cord Injuries
Azienda Sanitaria ASL Avellino 2

Unknown

Very Low Protein Diet and Renal Death in Chronic Kidney Disease (CKD)-ERIKA Study

Chronic Renal Insufficiency

Italy
Abilion Medical Systems AB

Recruiting

Intra-Nasal Mechanical Stimulation (INMEST) as a Treatment Method for the Relief of Symptoms of Dry Eye

Dry Eye | Dry Eye Syndromes

Denmark, Sweden
Million Marker Wellness, Inc.

Completed

Personalized Mobile Intervention to Reduce Exposure to Endocrine Disrupting Chemicals in Adults of Child-Bearing Age

Environmental Exposure | Survey | Health Literacy | Endocrine Disrupting Chemicals | Phthalate Exposure | Bisphenol A

United States
Azienda Sanitaria ASL Avellino 2

Unknown

Effects of Short-chain Fatty Acids on Inflammatory and Metabolic Parameters in Maintenance Hemodialysis (PLAN)

Endstage Renal Disease
Azienda Sanitaria ASL Avellino 2

Unknown

Renal Effects of Meditarranean Diet and Low-protein Diet With Ketoacids on Physiological Intestinal Mibrobiota in CKD (MEDIKA)

Chronic Renal Insufficiency

Italy
Azienda Sanitaria ASL Avellino 2

Unknown

Correction of Metabolic Acidosis in End Stage Renal Disease (ESRD) (UBI)

Metabolic Acidosis

Italy
Military Institute of Aviation Medicine

Unknown

Evaluation of an MRI-compatible Vital Signs Sensor System (OPTO-MRI)

Stress | Hyperventilation | Anxiety | Claustrophobia

Poland
Azienda Sanitaria ASL Avellino 2

Completed

Reduce Cardiovascular Calcifications to Reduce QT Interval in Dialysis (Independent)

Cardiovascular Mortality

Italy
Institute of Aviation Medicine, Oslo, Norway

Completed

The Effects of Vibration on Hypoxia

Hypoxia
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

Safety, Tolerability, and Antiviral Activity of ACH-0141625 or Placebo in Combination With Peginterferon and Ribavirin in Hepatitis C Virus (HCV) Positive Participants

Hepatitis C

United States, Belgium
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

Open-Label, 48-Week Extension Study of Elvucitabine in Combination With Background Antiretroviral Therapy (ART) for Participants Who Have Completed Study ACH443-014A

Human Immunodeficiency Virus (HIV)-1 Infection

United States, Spain, Germany, Dominican Republic
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

Safety and Antiviral Activity Study of ACH-126,443 (Beta-L-Fd4C) in Treatment-naive Adults With Chronic Hepatitis B Virus Infection

Hepatitis B, Chronic

Bulgaria, Former Yugoslavia
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

Evaluation of Safety, Tolerability, and Antiviral Activity of ACH-0143102 Plus Ribavirin In Treatment-naive Hepatitis C Virus Infection Genotype 1b Participants

Chronic Hepatitis C Infection

United States
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

Study of Once Daily Elvucitabine Versus Lamivudine in Participants With a Documented M184V Mutation (Resistance)

HIV Infections

United States
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

A Long-Term Treatment Study of ACH-0144471 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria

New Zealand, Korea, Republic of, Italy
Alexion
Achillion, a wholly owned subsidiary of Alexion

Terminated

Safety and Antiviral Study of ACH126, 433 (b-L-Fd4C) in Adults With Lamivudine-resistant Chronic Hepatitis B

Chronic Hepatitis B

United States, Canada, China
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Study of the Drug Interactions Between Danicopan and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy Adults

Healthy

United States
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

Study of a Single Dose of Danicopan in Healthy Participants

Healthy

New Zealand
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

Study of Radiolabeled Danicopan in Healthy Male Participants

Healthy

New Zealand
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

Elvucitabine/Efavirenz/Tenofovir Versus Lamivudine/Efavirenz/Tenofovir in Human Immunodeficiency Virus (HIV)-1 Infected, Treatment-naive Participants

HIV Infections

United States, Puerto Rico
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

Safety, Tolerability, and Efficacy of 12-weeks of Sovaprevir, ACH-3102, and Ribavirin in Treatment-naive GT-1 HCV Participants

Hepatitis C, Chronic

United States, Canada
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

An Open-Label Treatment Protocol to Provide Continued Elvucitabine Treatment

HIV Infections

United States
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Study of Single-dose ALXN2050 in Healthy Adults

Healthy

New Zealand
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Study of Modified Release Formulations of Danicopan in Healthy Adult Participants

Healthy

United Kingdom
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

Study of Different Forms of Danicopan (Tablet, Softgel Capsule, Liquid-filled Capsule) in Healthy Participants

Healthy

New Zealand
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

Study of Danicopan in Participants With Normal Kidney Function and Participants With Kidney Dysfunction

Healthy | Renal Dysfunction

United States
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

Study of Multiple Doses of Danicopan in Healthy Participants

Healthy

New Zealand
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Terminated

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ACH-0137171 in Participants With Chronic Hepatitis C Infection

HCV Infection

United States, Germany, Netherlands
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

Study of Danicopan in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United Kingdom, New Zealand, Korea, Republic of, Italy
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN

C3 Glomerulopathy | C3 Glomerulonephritis | Dense Deposit Disease | Immune Complex Mediated Membranoproliferative Glomerulonephritis | Membranoproliferative Glomerulonephritis Types I, II, and III

Netherlands, Australia, Belgium
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Study of Multiple Doses of ALXN2050 in Healthy Adults

Healthy

New Zealand
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Study of the Cardiac Effects of Danicopan in Healthy Adults

Healthy

United States
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

Study of Danicopan in Participants With Hepatic Impairment

Hepatic Impairment

United States
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Drug Interaction Study Between Danicopan and Midazolam, Fexofenadine, and Mycophenolate Mofetil in Healthy Participants

Healthy

New Zealand
UMC Utrecht
Center for Man in Aviation, Royal Netherlands Air Force

Terminated

Screening for Coronary Artery Disease USing Primary Evaluation With Coronary CTA in Aviation Medicine (SUSPECT) (SUSPECT)

Occupational Diseases | Coronary Artery Calcification | Coronary Artery Disease (CAD) | Aviator's; Disease

Netherlands
Alexion Pharmaceuticals, Inc.
Achillion, a wholly owned subsidiary of Alexion

Completed

Study of Danicopan in Participants With Paroxysmal Nocturnal Hemoglobinuria With Inadequate Response to Eculizumab (PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United Kingdom, United States, Italy
Monsoon Design Studio LLC
Healthark Wellness Solutions LLP

Completed

Study of Evoked Emotional Responses

Emotion, Expressed

India
Alexion Pharmaceuticals
Celerion; Achillion, a wholly owned subsidiary of Alexion

Completed

A Drug Interaction Study of ACH-0145228

Healthy

United States
Alexion Pharmaceuticals
Celerion; Achillion, a wholly owned subsidiary of Alexion

Completed

A Drug Interaction Study of Danicopan

Healthy

United States
Salena Killion
Michael J. Fox Foundation for Parkinson's Research

Unknown

Using Heavy Water to Study Cell Dynamics in Parkinson's Disease

HIV Infections | Parkinson's Disease

United States

Clinical Trials Sponsored by Avillion LLP

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