Clinical Trials Sponsored by BioMimetic Therapeutics

Total 6248 results

Fundación FLS de Lucha Contra el Sida, las Enfermedades...
Aelix Therapeutics

Completed

Study to Assess the Safety and Durability of Viral Control Beyond 24 Weeks of Analytical Treatment Interruption After the Administration of Candidate HIV-1 Vaccines DNA.HTI, MVA.HTI and ChAdOx1.HTI or Placebo in Early Treated HIV-1 Positive Individuals (ATI Extension of AELIX-002 Study)

HIV-1 Infection

Spain
Beth Israel Deaconess Medical Center
National Cancer Institute (NCI); Bayer; Dana-Farber Cancer Institute; Brigham and... and other collaborators

Completed

Sorafenib Therapy Prior to Radiofrequency Ablation for Intermediate Sized Hepatocellular Cancer

Hepatocellular Cancer

United States
Pear Therapeutics, Inc.
National Institute on Drug Abuse (NIDA); Kaiser Foundation Research Institute; Whitman-Walker Institute, Inc... and other collaborators

Completed

Feasibility Study of Novel Prescription Digital Therapeutic Supporting Unobserved Buprenorphine Initiation & Adherence

Opioid Use Disorder

United States
Neurocrine Biosciences
Oregon Health and Science University; University of California, San Francisco; Veristat, Inc... and other collaborators

Completed

Safety Study of AADC Gene Therapy (VY-AADC01) for Parkinson's Disease (AADC)

Parkinson's Disease

United States
University of Southern California
National Institute on Aging (NIA); Alzheimer's Therapeutic Research Institute; Wake Forest University Health Sciences

Completed

The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF)

Alzheimer's Disease | Amnestic Mild Cognitive Impairment

United States
Tanja Andrea Gruber
Amgen; Kura Oncology, Inc.; Pediatric Oncology Experimental Therapeutics Investigators... and other collaborators

Recruiting

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

Lymphoblastic Leukemia

United States
Milton S. Hershey Medical Center
Columbia University; National Institutes of Health (NIH); Research Foundation... and other collaborators

Active, not recruiting

reSET-O RCT (Randomized Controlled Trial)

Opioid-use Disorder

United States
Atossa Therapeutics, Inc.
Quest Diagnostics-Nichols Insitute; National Reference Laboratory for Breast... and other collaborators

Completed

ForeCYTE Breast Aspirator for Sample Collection and Cytological Testing of Nipple Aspirate Fluid

Breast Neoplasms

United States
University of Southern California
National Institute of Mental Health (NIMH); Alzheimer's Therapeutic Research... and other collaborators

Active, not recruiting

Characterizing Cognitive Decline in Late Life Depression: The ADNI Depression Project (ADNI-D)

Major Depression | Late Life Depression (LLD)

United States
University Hospitals of Derby and Burton NHS Foundation...
Wellcome Trust; Nottingham University Hospitals NHS Trust; BioPhage Theraputics...

Withdrawn

Assessing the Efficacy of Anti-staphylococcal Phages in the Management of Infected Foot Ulcers in Diabetes (PDFI)

Diabetes | Diabetic Foot | Diabetic Foot Infection

United Kingdom
Chris Goss
Medical University of South Carolina; University of Washington; Cystic Fibrosis... and other collaborators

Completed

Standardized Treatment of Pulmonary Exacerbations II (STOP2)

Pulmonary Cystic Fibrosis

United States, Canada
Assistance Publique - Hôpitaux de Paris
INSERM U 1163 - Laboratory of molecular mechanisms of hematologic disorders...

Recruiting

Interest of Famotidine in Children With Sickle Cell Disease (FAMODREP)

Sickle Cell Disease

France
Amgen
Innovative Therapies For Children with Cancer Consortium; Therapeutic Advances...

Active, not recruiting

Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia (ALL)

Spain, United Kingdom, United States, Korea, Republic of, Czechia, France, Russian Federation, Saudi Arabia, Thailand, Canada, Italy, Singapore, Turkey, Taiwan, Portugal, Poland, Romania, Brazil, Australia, Greece, Argentina, Mexico, Austr... and more
NS Pharma, Inc.
Cooperative International Neuromuscular Research Group; Nippon Shinyaku Co.... and other collaborators

Completed

Extension Study of NS-065/NCNP-01 in Boys With Duchenne Muscular Dystrophy (DMD)

Duchenne Muscular Dystrophy

United States, Canada
Opsona Therapeutics Ltd.
M.D. Anderson Cancer Center; Montefiore Medical Center; New York Presbyterian... and other collaborators

Completed

A Phase I/II Study of OPN-305 in Second-line Lower Risk Myelodysplastic Syndrome

Myelodysplastic Syndrome

United States
Opsona Therapeutics Ltd.
M.D. Anderson Cancer Center; Montefiore Medical Center; New York Presbyterian... and other collaborators

Completed

Follow up Protocol to the Phase I/II Study of OPN-305 in Second-line or Third-line Lower Lower Risk Myelodysplastic Syndrome

Myelodysplastic Syndrome

United States
University of Southern California
National Institute on Aging (NIA); Northern California Institute of Research... and other collaborators

Recruiting

Alzheimer's Disease Neuroimaging Initiative 4 (ADNI4)

Dementia | Alzheimer Disease | Mild Cognitive Impairment

United States, Canada
Invex Therapeutics Ltd.
Premier Research Group plc; University Hospitals Birmingham Neuro Ophthalmology... and other collaborators

Terminated

A Trial to Determine the Efficacy and Safety of Presendin in IIH (IIH EVOLVE)

Idiopathic Intracranial Hypertension

Israel, Germany, Australia, United States, United Kingdom, New Zealand
Better Therapeutics
University of Colorado, Denver; CPC Clinical Research; Ascension Health; Department... and other collaborators

Active, not recruiting

Digital Therapeutic Based Investigation to Improve Glycemic Control in Patients With Type 2 Diabetes and Residual Hyperglycemia on Stable Medical Therapy (BRIGHT)

Diabetes Mellitus, Type 2

United States
Weill Medical College of Cornell University
Children's Hospital Colorado; SLC6A1 Connect; STXBP1 Foundation; Clara Inspired; University... and other collaborators

Enrolling by invitation

Phenylbutyrate for Monogenetic Developmental and Epileptic Encephalopathy

Developmental and Epileptic Encephalopathy | STXBP1 Encephalopathy With Epilepsy, SLC6A1 Neurodevelopmental Disorder

United States
The Queen Elizabeth Hospital
University of Adelaide; University of South Australia; Basil Hetzel Institute... and other collaborators

Completed

Evaluation of Transdermal Nicotine Replacement Therapy (NRT) Activity Through Metabolic Induction

Smoking | Addiction

Australia
University of Colorado, Boulder
National Institutes of Health (NIH); Radiological Society of North America; Psychophysiologic... and other collaborators

Completed

Mind-body Treatments for Chronic Back Pain

Chronic Pain | Back Pain Lower Back Chronic | Back Pain, Low

United States
University of Southern California
National Institute on Aging (NIA); Northern California Institute of Research... and other collaborators

Completed

Alzheimer's Disease Neuroimaging Initiative 2 (ADNI2)

Mild Cognitive Impairment (MCI) | Alzheimer's Disease (AD) | Significant Memory Concern (SMC) | Early Mild Cognitive Impairment (EMCI) | Late Mild Cognitive Impairment (LMCI)

United States, Canada
Yale University
National Institute of Mental Health (NIMH); University of Pennsylvania; Columbia... and other collaborators

Recruiting

A Translational and Neurocomputational Evaluation of a Dopamine Receptor 1 Partial Agonist for Schizophrenia

Early Course Schizophrenia Spectrum Disorder

United States
Memorial Sloan Kettering Cancer Center
Merck Sharp & Dohme LLC; Mirati Therapeutics Inc.; Astex Pharmaceuticals, Inc.; Stand Up To Cancer and other collaborators

Active, not recruiting

Pembrolizumab (Immunotherapy Drug) in Combination With Guadecitabine and Mocetinostat (Epigenetic Drugs) for Patients With Advanced Lung Cancer.

Lung Cancer

United States
Cyprium Therapeutics, Inc.
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Molecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper Deficiency

Menkes Disease | Occipital Horn Syndrome | Unexplained Copper Deficiency

United States
University Hospital, Lille
Regional Agency of Sante Nord Pas-de-Calais; OméDIT (Observatory of Medicines...

Not yet recruiting

DETECT-IP: a Clinical Decision Support System and Intelligent Procedures to Counter Some Adverse Drug Events in Older Hospital Patients (DETECT-IP:)

Acute Renal Failure | Patient Acceptance of Health Care
University of Southern California
National Institute on Aging (NIA); Northern California Institute of Research... and other collaborators

Recruiting

Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) (ADNI3)

Mild Cognitive Impairment (MCI) | Alzheimer's Disease (AD)

United States, Canada
Addis Ababa University
Center for Innovative Drug Development and Therapeutic Trials for Africa,... and other collaborators

Not yet recruiting

Concomitant Curcumin Palliative Radiotherapy in Advanced Cervical Cancer Trial (CuPRAC)

Cervical Cancer
University of Oxford
Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Qidong... and other collaborators

Completed

Qidong Hepatitis B Intervention Study

Liver Diseases | Hepatitis B | Liver Neoplasms

United Kingdom, China
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
Universitaire Ziekenhuizen KU Leuven
KU Leuven; Hospital Clinic of Barcelona; MDx Health; Biomedical Research Foundation... and other collaborators

Not yet recruiting

Prospective Collection of Samples for Urothelial Cancer of Bladder (ProCSUCaB)

Bladder Cancer
Morten Mau-Soerensen
Hospices Civils de Lyon; Gustave Roussy, Cancer Campus, Grand Paris; Institut... and other collaborators

Unknown

Selinexor in Patients With Advanced Thymoma and Thymic Carcinoma (TET-SEL)

Thymoma | Advanced Thymic Epithelial Tumour

Denmark, France
Cambridge University Hospitals NHS Foundation Trust
GlaxoSmithKline; National Institute for Health Research, United Kingdom; Kidney... and other collaborators

Recruiting

PROphylaxis for paTiEnts at Risk of COVID-19 infecTion -V (PROTECT-V)

Covid19

United Kingdom
William Lee
Medical University of South Carolina; National Institute of Diabetes and Digestive... and other collaborators

Completed

Safety Study of Ornithine Phenylacetate to Treat Patients With Acute Liver Failure/Severe Acute Liver Injury (STOP-ALF)

Acute Liver Failure | Acute Liver Injury

United States
University of Southern California
Medical University of South Carolina; National Institute on Aging (NIA); Alzheimer... and other collaborators

Recruiting

Life's End Benefits of Cannabidiol and Tetrahydrocannabinol (LiBBY)

Dementia | Agitation

United States
Talaris Therapeutics Inc.
Duke University; University of Florida; St. Christopher's Hospital for Children; Hahnemann University Hospital and other collaborators

Completed

Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies

Sickle Cell Disease

United States
University of Colorado, Denver
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Physiological Mechanisms of Therapeutic Horseback Riding Intervention Effects in a Psychiatric Population of ASD Youth

Mental Disorders | Autism Spectrum Disorder

United States
Frontera Therapeutics
Peking Union Medical College Hospital; The First Affiliated Hospital of Soochow... and other collaborators

Not yet recruiting

Gene Therapy for Wet AMD

Neovascular Age-related Macular Degeneration
Xuanwu Hospital, Beijing
H. Lundbeck A/S; Hoffmann-La Roche; Genentech, Inc.; Life Molecular Imaging SA; APRINOIA... and other collaborators

Recruiting

A Direct Comparative Study of Tau Tracer in Patients With Alzheimer's Disease (HTH)

Alzheimer Disease

China
Frantz Viral Therapeutics, LLC
M.D. Anderson Cancer Center; University of Michigan; The Cleveland Clinic; Amarex... and other collaborators

Recruiting

Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3) (ART-CIN_IIB)

HPV Infection | CIN 2/3 | Cervical Dysplasia | Pre-Cancerous Dysplasia | HPV Related Disease

United States
University Hospital Southampton NHS Foundation...
Cancer Research UK; The Christie NHS Foundation Trust; Celldex Therapeutics; Oxford... and other collaborators

Active, not recruiting

A Combination of Rituximab and Varlilumab Immunotherapy in Patients With B-cell Lymphoma (RiVa)

B Cell Lymphoma

United Kingdom
National Institute of Dental and Craniofacial Research...
National Institute of Neurological Disorders and Stroke (NINDS); Sorrento Therapeutics...

Recruiting

Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer

Palliative Care | Intractable Pain

United States
Minneamrita Therapeutics LLC
Cancer Research UK; Barts & The London NHS Trust; Queen Mary University of London and other collaborators

Completed

A Phase II, International Open Label Trial of Minnelide™ in Patients With Refractory Pancreatic Cancer (MinPAC)

Pancreatic Cancer

United States
Albert Einstein College of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

ScreenPlus: A Comprehensive, Flexible, Multi-disorder Newborn Screening Program (ScreenPlus)

Mucopolysaccharidosis II | Fabry Disease | Niemann-Pick Disease, Type C | Mucopolysaccharidosis VI | Lysosomal Acid Lipase Deficiency | Metachromatic Leukodystrophy | Gaucher Disease | Cerebrotendinous Xanthomatosis | Mucopolysaccharidosis IV A | GM1 Gangliosidosis | Mucopolysaccharidosis VII | Acid Sphingomyelinase... and other conditions

United States
PIQUR Therapeutics AG
Hospital Universitari Vall d'Hebron Research Institute; Institut Català d'Oncologia and other collaborators

Completed

PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)

Metastatic Breast Cancer

Spain, United Kingdom
National Human Genome Research Institute (NHGRI)
National Center for Advancing Translational Sciences (NCATS); Therapeutics...

Completed

Phase I Clinical Trial of ManNAc in Patients With GNE Myopathy or Hereditary Inclusion Body Myopathy (HIBM)

GNE Myopathy | Hereditary Inclusion Body Myopathy (HIBM)

United States
University of Manchester
University College, London; Manchester University NHS Foundation Trust; Orchard... and other collaborators

Active, not recruiting

Gene Therapy With Modified Autologous Hematopoietic Stem Cells for Patients With Mucopolysaccharidosis Type IIIA

Mucopolysaccharidosis Type IIIA

United Kingdom
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Terminated

Serum-Free Thymus Transplantation in DiGeorge Anomaly (SerumFree)

DiGeorge Anomaly
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Thymus Transplantation Dose in DiGeorge #932

DiGeorge Syndrome | DiGeorge Anomaly | Complete DiGeorge Anomaly | Complete DiGeorge Syndrome

United States

Clinical Trials Sponsored by BioMimetic Therapeutics

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