Clinical Trials Sponsored by Center for Translational Medicine

Total 1455 results

Center for Translational Medicine

Unknown

Use of Whole-Body Periodic Acceleration Therapy To Aches and Pains (Exer-Rest)

Pain | Balance | Stiffness | Abnormal Gait

United States
Maastricht University Medical Center
Center for Translational Molecular Medicine

Completed

Cross-over Study on Effect of Lipid Lowering by Acipimox on Cardiac and Skeletal Muscle Mitochondrial Function (ACP)

Diabetes Mellitus, Type 2 | Cardiomyopathy, Dilated

Netherlands
Maastricht University Medical Center
Dutch Heart Foundation; Center for Translational Molecular Medicine

Completed

ParisK: Correlation of Imaging Techniques With Histology (ParisK)

Stroke | Plaque, Atherosclerotic

Netherlands
UMC Utrecht
Center for Translational Molecular Medicine; Dutch Cancer Society; Vrienden UMC...

Recruiting

Image-guided Targeted Doxorubicin Delivery With Hyperthermia to Optimize Loco-regional Control in Breast Cancer (i-GO)

Breast Cancer | Breast Neoplasms | Metastatic Cancer | Metastatic Breast Cancer | Stage IV Breast Cancer | Invasive Ductal Breast Cancer | Invasive Ductal Carcinoma of Female Breast | Adenocarcinoma Breast

Netherlands
Washington University School of Medicine
National Center for Advancing Translational Sciences (NCATS)

Recruiting

Pilot Study for Postoperative Machine Learning

Surgery--Complications

United States
Washington University School of Medicine
National Center for Advancing Translational Sciences (NCATS)

Not yet recruiting

Impact of Basic Needs Assessment and Support to Improve Colposcopy Show Rate (BASICS)

Cervical Cancer

United States
German Cancer Research Center
German Consortium for Translational Cancer Research

Recruiting

Molecularly Aided Stratification for Tumor Eradication Research (NCT-MASTER)

Rare Cancers | Multiomics

Germany
German Cancer Research Center
German Consortium for Translational Cancer Research

Completed

Afatinib in Advanced NRG1-Rearranged Malignancies

Metastatic and Locally Advanced NRG1-rearranged Malignancies

Germany
Paris Translational Research Center for Organ Transplantation

Recruiting

Molecular Landscape of Microvascular Inflammation in Kidney Allografts

Kidney Rejection Transplant

France
Paris Translational Research Center for Organ Transplantation

Enrolling by invitation

Trajectories of FEV1 After Lung Transplantation (TRAJLUNG)

Lung Transplant Failure and Rejection | Chronic Lung Allograft Dysfunction

France
Paris Translational Research Center for Organ Transplantation

Completed

Donor Derived Cell-free DNA and Rejection of Kidney Allografts

Kidney Rejection Transplant
Paris Translational Research Center for Organ Transplantation

Completed

Multidimensional System to Dynamically Predict Graft Survival After Kidney Transplantation (DYNAKT)

Kidney Transplant Failure

United States, Argentina, Brazil, Chile, Croatia, France, Spain
Paris Translational Research Center for Organ Transplantation

Recruiting

Development and Validation of a Comprehensive Classification Automation System for Kidney Allograft Biopsies

Kidney Transplant Rejection | Pathology

France
Paris Translational Research Center for Organ Transplantation

Completed

Estimating Glomerular Filtration Rate in Kidney Transplant Recipients

Kidney Transplantation | Glomerular Filtration Rate

United States, Croatia, France, Italy
Paris Translational Research Center for Organ Transplantation

Unknown

Trajectories of Glomerular Filtration Rate and Progression to End Stage Renal Disease After Kidney Transplantation (TRAJAKT)

Kidney Transplant Failure | Kidney Function Issue

United States, Belgium, Croatia, France
Albert Einstein College of Medicine
National Center for Advancing Translational Sciences (NCATS)

Recruiting

Telehealth Behavioral Migraine Management (TeleBMM)

Migraine

United States
Washington University School of Medicine
National Center for Advancing Translational Sciences (NCATS)

Recruiting

A Role for FGF21 in Postprandial Nutrient Homeostasis After RYGB (FGB)

Obesity

United States
Washington University School of Medicine
National Center for Advancing Translational Sciences (NCATS)

Completed

Median Nerve Stimulation Pilot (MNS)

Tourette Syndrome | Tic Disorders | Tic Disorder, Chronic Motor or Vocal

United States
Washington University School of Medicine
National Center for Advancing Translational Sciences (NCATS)

Completed

Open-label MNS for Tourette Syndrome

Tourette Syndrome | Tic Disorder, Chronic Motor or Vocal

United States
Paris Translational Research Center for Organ Transplantation

Completed

Human Versus Computer-based Predictions of Long Allograft Survival (iBox vs Human)

Kidney Transplant Failure

France
Paris Translational Research Center for Organ Transplantation

Unknown

Long-term Outcomes After Conversion to Belatacept

Immunosuppression | Kidney Transplant Failure and Rejection | Drug Effect Prolonged | Graft Loss
Paris Translational Research Center for Organ Transplantation

Completed

Development and Validation of a Multidimensional Score to Predict Long-term Kidney Transplant Outcomes (iBOX)

Kidney Transplantation

France, United States, Belgium
Paris Translational Research Center for Organ Transplantation

Completed

Complement-activating Anti-human Leucocyte Antigen Donor Specific Antibodies in Solid Organ Transplantation

Organ Transplant Recipients
Maastricht University Medical Center
Center for Translational Molecular Medicine; Top Institute Food and Nutrition

Completed

Effect of Pyridoxamine Supplementation on Vascular Function and Insulin Sensitivity

Abdominal Obesity Metabolic Syndrome

Netherlands
Jonsson Comprehensive Cancer Center
National Center for Advancing Translational Sciences (NCATS)

Recruiting

Biologic Association Between Metabolic Magnetic Resonance-positron Emission Tomograph (MR-PET) and Tissue Measures of Glycolysis in Brain Tumors of Infiltrating Glioblastoma Cells

Glioblastoma Multiforme | Epidermal Growth Factor Receptor | Glycolytic Index

United States
Gitte Moos Knudsen
Danish Center for Sleep Medicine; Center for translational Neuromedicine, University...

Completed

Effects of Sleep Deprivation and Adrenergic Inhibition on Glymphatic Flow in Humans

Sleep Wake Disorders | Sleep | Sleep Deprivation

Denmark
Paris Translational Research Center for Organ Transplantation
Center for Cardiovascular Research Berlin

Completed

Anti-Angiotensin II Type 1 Receptor Antibodies and Kidney Transplant Outcomes

Kidney Transplant Failure and Rejection

France
Shenzhen Institute for Innovation and Translational...
Dongguan People's Hospital

Completed

Anti-CD19 Chimeric Antigen Receptor (CAR)-Transduced T Cell Therapy for Patients With B Cell Malignancies

Lymphoma | Chronic Lymphocytic Leukemia | Acute Lymphocytic Leukemia

China
Xinhua Translational Institute for Cancer Pain,...

Completed

Intelligent Pain Management System for Assessing Pain in Cancer Patients

Neoplasms | Pain

China
Washington University School of Medicine
ICTS BJH; Center for Diabetes Translation Research

Completed

Safety and Feasibility of a Low Carbohydrate Diet in Children With Type 1 Diabetes

Type 1 Diabetes

United States
Translational Research Center for Medical Innovation...
Jikei University School of Medicine

Completed

PSA Levels and Biopsy Samples After Implant Radiation and Hormone Therapy in Patients With Stage I or Stage II Prostate Cancer (SHIP36B)

Prostate Cancer

Japan
University of Colorado, Denver
National Center for Advancing Translational Sciences (NCATS); Colorado Clinical...

Completed

Helping Moms to be Healthy After Baby

Obesity | Weight Loss | Diet Modification

United States
Translational Research Center for Medical Innovation...
Showa University School of Medicine

Completed

Outcome Study of Lanthanum Carbonate Compared With Calcium Carbonate in Hemodialysis Patients : Landmark Study (LANDMARK)

Hemodialysis | Hyperphosphatemia

Japan
Translational Research Center for Medical Innovation...
Showa University School of Medicine

Completed

PRevention of End Stage Kidney Disease by Darbepoetin Alfa In Chronic Kidney Disease Patients With nondiabeTic Kidney Disease (PREDICT)

Diabetes | Chronic Kidney Disease

Japan
University of Colorado, Denver
National Center for Advancing Translational Sciences (NCATS)

Recruiting

PTH And Calcium Responses to Exercise in Older Adults Experiment 2 (PACE Sr. 2)

Osteoporosis

United States
University of Colorado, Denver
National Center for Advancing Translational Sciences (NCATS)

Completed

Analysis of B Cells From Autoimmune Individuals

Rheumatoid Arthritis | Type 1 Diabetes | Lupus Erythematosus

United States
Roswell Park Cancer Institute
National Center for Advancing Translational Sciences (NCATS)

Completed

Chemokine Modulation Therapy and Standard Chemotherapy Before Surgery for the Treatment of Early Stage Triple Negative Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Prognostic Stage I Breast Cancer AJCC v8 | Prognostic... and other conditions

United States
University of Colorado, Denver
National Center for Advancing Translational Sciences (NCATS)

Completed

Liver and Fat Regulation in Overweight Adolescent Girls (APPLE)

Obesity | Polycystic Ovarian Syndrome | Hepatic Steatosis

United States
University of Colorado, Denver
National Center for Advancing Translational Sciences (NCATS)

Completed

Reprometabolic Syndrome Mediates Subfertility in Obesity

Obesity | Infertility | Hyperinsulinemia | Hypogonadotropic Hypogonadotropism

United States
Roswell Park Cancer Institute
National Center for Advancing Translational Sciences (NCATS)

Not yet recruiting

Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer

Recurrent Colorectal Carcinoma | Locally Advanced Colorectal Carcinoma | Stage III Colorectal Cancer

United States
University of Colorado, Denver
National Center for Advancing Translational Sciences (NCATS)

Active, not recruiting

The Colonic Microbiome and Mucosal Immunity in Inflammatory Bowel Disease and Ankylosing Spondylitis

Inflammatory Bowel Diseases (IBD) | Ankylosing Spondylitis (AS)

United States
University of Colorado, Denver
National Center for Advancing Translational Sciences (NCATS)

Completed

Role of Acute Exercise Modality on Appetite Regulation and Energy Intake

Appetite Regulation | Energy Intake | Acute Exercise

United States
Yale University
National Center for Advancing Translational Sciences (NCATS)

Recruiting

Role Of Non-Specific Effects in The Treatment of Depression With Esketamine (ROSETTE)

Depressive Episode

United States
Mayo Clinic
National Center for Advancing Translational Sciences (NCATS)

Completed

A Study to Evaluate Unintended Prolonged Opioid Use

Opioid Use

United States
Indiana University
National Center for Advancing Translational Sciences (NCATS)

Terminated

Collaborative Care for Opioid Dependence And Pain Pilot Study (CCODAPP)

Chronic Pain | Opioid Dependence

United States
Auburn University
National Center for Advancing Translational Sciences (NCATS)

Terminated

Anti-anxiety Biotics for Breast Cancer Survivors (ABBCS)

Breast Cancer Female | Anxiety Generalized

United States
Indiana University
National Center for Advancing Translational Sciences (NCATS)

Completed

Effect of Prebiotics on the Gut Microbiome Profile and Beta Cell Function

Type 1 Diabetes

United States
Mayo Clinic
National Center for Advancing Translational Sciences (NCATS)

Completed

MPO Inhibitor A_Zeneca for HFpEF

Heart Failure

United States
Translational Research Center for Medical Innovation...

Completed

A Study on the Regenerative Treatment of Tympanic Membrane With NPC-18 and FBG-18

Tympanic Membrane Perforation
Translational Research Center for Medical Innovation...

Completed

Epirubicin and Cyclophosphamide Followed By Docetaxel and Trastuzumab in Treating Women With HER2-Positive Stage III or Stage IV Breast Cancer

Breast Cancer

Japan

Clinical Trials Sponsored by Center for Translational Medicine

Sponsors and Collaborators

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CROs in Kazakhstan

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