Clinical Trials Sponsored by Chroma Therapeutics

Total 6828 results

Celldex Therapeutics

No longer available

Expanded Access (Compassionate Use) Treatment Protocol Rindopepimut (CDX-110)

Recurrent GBM
United Therapeutics

Completed

Safety and Tolerability of Rapid Dose Titration of Subcutaneous Remodulin® Therapy in PAH Subjects (RAPID) (RAPID)

Pulmonary Arterial Hypertension
Osiris Therapeutics

Terminated

Study to Evaluate the Safety and Efficacy of CHAM* for the Treatment of Diabetic Foot Ulcers (*OTI-15-01)

Chronic Diabetic Foot Ulcers

United States
PTC Therapeutics

Completed

A Single Dose Evaluation of the Effects of Moderate Hepatic Impairment on Deflazacort Pharmacokinetics

Hepatic Impairment

United States
PTC Therapeutics

Completed

Evaluate Effects of Multiple Doses of Rifampin and Clarithromycin on the Single Dose Pharmacokinetics of Deflazacort

Healthy Volunteers

United States
Osiris Therapeutics

Completed

GrafixPRIME® for the Treatment of Chronic Diabetic Foot Ulcers

Foot Ulcer, Diabetic

United States
Celldex Therapeutics

Completed

A Study to Evaluate CDX-301 (rhuFlt3L) in Healthy Volunteers

Healthy

United States
Entasis Therapeutics

Completed

Evaluation of the Safety, Tolerability and Pharmacokinetics of Intravenous ETX2514 Administered in Healthy Subjects

Acinetobacter Baumannii Infection

Australia
Karuna Therapeutics

Completed

Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium

Schizophrenia

United States
United Therapeutics

Withdrawn

Study to Evaluate Efficacy and Safety of Oral Treprostinil in Subjects With Pulmonary Hypertension (PH) Associated With Sickle Cell Disease (SCD)

Pulmonary Hypertension Associated With Sickle Cell Disease
Osiris Therapeutics

Terminated

TruSkin®: Study for Treatment of Chronic Venous Leg Ulcers

Chronic Venous Leg Ulcers

United States
vTv Therapeutics

Completed

Add Glucokinase Activator to Target A1c (AGATA)

Diabetes Mellitus, Type 2

United States
Intarcia Therapeutics

Completed

A Study to Evaluate Cardiovascular Outcomes in Patients With Type 2 Diabetes Treated With ITCA 650

Type 2 Diabetes

Finland, United States, Bulgaria, Poland, South Africa, Denmark, Turkey, Slovakia, Germany
Nektar Therapeutics

Completed

A Study in Cancer Patients to Evaluate the Effect of a Single Dose of NKTR-102 (Etirinotecan Pegol) on the QTc Interval and to Assess Pharmacokinetics and Safety

Advanced Cancer | Metastatic Solid Tumors

United States
Centrexion Therapeutics

Completed

Safety and Tolerability of 4975 in the Treatment of Moderate to Severe Knee Pain Due to Osteoarthritis (OA)

Osteoarthritis of the Knee

United States
Cytori Therapeutics

Completed

Safety and Feasibility Trial of Adipose-Derived Regenerative Cells in the Treatment of Chronic Myocardial Ischemia (ATHENA)

Myocardial Ischemia

United States
Cytori Therapeutics

Completed

Safety & Efficacy of Adipose-Derived Regenerative Cells in the Treatment of Chronic Myocardial Ischemia (ATHENA II) (ATHENA II)

Myocardial Ischemia

United States
Prexton Therapeutics

Completed

A Phase I, Double Blind, Placebo Controlled, First in Human, Single and Multiple Ascending Oral Dose, Safety, Tolerability and Pharmacokinetic Study in Healthy Male and Female Subjects

Parkinson's Disease

United Kingdom
Cognition Therapeutics

Completed

Ascending Dose Study of CT1812 in Healthy Volunteers

Cognitive Impairment

Australia
DNA Therapeutics

Completed

DNA Repair Inhibitor & Irradiation on Melanoma (DRIIM)

Local Metastatic Melanoma

France
Acorda Therapeutics

Completed

A Pharmacokinetic Study to Assess Dose Proportionality, Safety and Tolerability of Diazepam Nasal Spray in Healthy Adult Volunteers

Healthy

United States
Acorda Therapeutics

Completed

A Study of the Safety and Pharmacokinetics of Levodopa Following Administration of CVT 301 (Levodopa Inhalation Powder) in Adults With Asthma

Asthma

United States
Intarcia Therapeutics

Completed

A Study to Evaluate ITCA 650 Compared to Sitagliptin as add-on Therapy for the Treatment of Type 2 Diabetes

Type 2 Diabetes

United States, Croatia, Latvia, Denmark, Germany
Therapeutics, Inc.

Completed

Blinded Study of Topical Investigational Lotion Vs. Approved Cream in Treatment of Plaque Psoriasis

Plaque Psoriasis

United States
United Therapeutics

Completed

Remodulin® to Oral Treprostinil Transition

Pulmonary Arterial Hypertension

United States
Therapeutics, Inc.

Completed

A Study to Determine the Efficacy and Safety of Halobetasol Propionate Lotion 0.05% in Subjects With Plaque Psoriasis

Psoriasis | Plaque Psoriasis

United States
Cytori Therapeutics

Withdrawn

Registry of Celution Device for Processing ADRCs and Healing in Muscle and Ligament Sports Injuries (ACHILLES)

Muscle Tear

United Kingdom
BIND Therapeutics

Completed

A Phase 2 Study to Determine the Safety and Efficacy of BIND-014 (Docetaxel Nanoparticles for Injectable Suspension), Administered to Patients With Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer | CRPC

United States
Cytori Therapeutics

Withdrawn

Cardiac REgistry of Celution Device for the Processing of Adipose-derived Regenerative Cells (CREATE)

Coronary Artery Disease | Heart Failure
Cytori Therapeutics

Completed

Feasibility of Obtaining ADRCs From Discarded Thermal Burn Eschar Tissue Using Investigational Celution® System

Thermal Burn

United States
BIND Therapeutics

Completed

A Study of BIND-014 Given to Patients With Advanced or Metastatic Cancer

Cancer | Metastatic Cancer | Solid Tumors

United States
United Therapeutics

Withdrawn

Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis

Pulmonary Fibrosis | Pulmonary Hypertension

United States
Acorda Therapeutics

Completed

A Phase 2b Study of Dalfampridine 10mg Extended Release Tablet in Subjects With Chronic Deficits After Ischemic Stroke

Ischemic Stroke

United States
Vicus Therapeutics

Unknown

Study of Sorafenib With or Without VT-122 in Patients With Hepatocellular Carcinoma (HCC)

HCC

United States
Noven Therapeutics

Completed

Pharmacokinetic Evaluation of Brisdelle™ (Formerly Known as Mesafem) Following Single & Repeat Oral Administration in Healthy Postmenopausal Women (N30-005)

Postmenopausal Symptoms

United States
Intarcia Therapeutics

Completed

A Study to Evaluate ITCA 650 for the Treatment of Type 2 Diabetes

Type 2 Diabetes

United States
Proteon Therapeutics

Completed

A Phase 1-2 Study of PRT-201 Administered in Chronic Kidney Disease (CKD) Patients

Chronic Kidney Disease

United States
Aerpio Therapeutics

Completed

Safety and Pilot Efficacy of AKB-9778 in Subjects With Diabetic Macular Edema

Diabetic Macular Edema (DME)

United States
United Therapeutics

Completed

Tyvaso Dosing and Titration Evaluation: TyTRATE Registry

Pulmonary Arterial Hypertension

United States, Puerto Rico
Alaunos Therapeutics

Completed

Adenoviral Vector Monotherapy or Combination With Chemotherapy in Subjects With Recurrent/Metastatic Breast Cancer.

Breast Cancer Nos Metastatic Recurrent

United States
Alaunos Therapeutics

Completed

Safety Study of Adenovirus Vector Engineered to Express hIL-12 in Combination With Activator Ligand to Treat Melanoma

Melanoma

United States
Pulse Therapeutics

Terminated

A Safety Evaluation of the Use of Magnetic-guided Iron Particles

Ischemic Stroke

Australia
Summit Therapeutics

Completed

A Phase 1b Study of SMT C1100 in Subjects With Duchenne Muscular Dystrophy (DMD)

Duchenne Muscular Dystrophy

United Kingdom
Halozyme Therapeutics

Completed

Liquid Meal Study With Insulin Lispro With/Without Recombinant Human Hyaluronidase PH20 (rHuPH20) and Regular Human Insulin With rHuPH20 to Compare Pharmacokinetics, Postprandial Glycemic Response, and Optimal Insulin Dose in Participants With Type 2 Diabetes Mellitus (T2DM)

Diabetes Mellitus, Type 2

United States
Guided Therapeutics

Unknown

Initial Study With the CNDS Advanced Cervical Scan to Recalibrate Spectral Data for Use in Future Screening Studies (Spectral)

Cervical Disease

United States
Halozyme Therapeutics

Completed

A Pharmacokinetic and Glucodynamic Study of Subcutaneously Administered Insulin Analogs With rHuPH20 Compared to Insulin Analogs Alone

Healthy

United States
Chelsea Therapeutics

Completed

Safety and Benefit Study of Droxidopa to Treat Patients With Intradialytic Hypotension (IDH201)

Intradialytic Hypotension

United States
Acorda Therapeutics

Completed

Safety and Tolerability of Dalfampridine in Subjects With Cerebral Palsy

Cerebral Palsy (CP)

United States
Ocera Therapeutics

Completed

AST-120 Used to Treat Mild Hepatic Encephalopathy (ASTUTE)

Mild Hepatic Encephalopathy

United States
Ocera Therapeutics

Completed

Safety and Efficacy of AST-120 in Patients With Non-Constipating Irritable Bowel Syndrome

Irritable Bowel Syndrome

United States, Belgium

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