Clinical Trials Sponsored by Cone Health System Cancer Center

Total 14124 results

National Cancer Institute (NCI)

Recruiting

Clinical and Genetic Studies of Li-Fraumeni Syndrome

Neoplasms | Li-Fraumeni Syndrome | Tp53 Mutations

United States
National Cancer Institute (NCI)

Recruiting

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

Lymphoma | Breast Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer

United States
National Cancer Institute (NCI)

Recruiting

Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies

Sarcoma | Neuroblastoma | Retinoblastoma | Renal Cancer | Endocrine Tumors

United States
National Cancer Institute (NCI)

Recruiting

Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment

Chronic Lymphocytic Leukemia (CLL) | Hairy Cell Leukemia (HCL) | Cutaneous T Cell Lymphoma (CTCL) | Non-Hodgkins Lymphoma (NHL) | Adult T Cell Lymphoma (ATL)

United States
National Cancer Institute (NCI)

Recruiting

Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

Thyroid Neoplasms | Neuroblastoma | Parathyroid Neoplasms | Endocrine Tumors | Adrenal Neoplasm

United States
National Cancer Institute (NCI)

Recruiting

Collection of Tissue Samples for Cancer Research

Neoplasms | Multiple Myeloma | Myelodysplastic Syndrome | Lymphomas

United States, Canada
National Cancer Institute (NCI)

Recruiting

Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme

Glioblastoma Multiforme

United States
National Cancer Institute (NCI)

Recruiting

Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma

Melanoma | Dysplastic Nevus Syndrome

United States
National Cancer Institute (NCI)

Recruiting

Collection of Blood From Patients With Cancer

Breast Cancer | Lung Cancer | Prostate Cancer | Colon Cancer | Liver Cancer

United States
National Cancer Institute (NCI)

Recruiting

Cancer in Inherited Bone Marrow Failure Syndromes

Fanconi Anemia | Dyskeratosis Congenita | Diamond Blackfan Anemia | Shwachman Diamond Syndrome | Inherited Bone Marrow Failure Syndrome, Aplastic Anemia

United States
National Cancer Institute (NCI)

Recruiting

Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders

Kidney Cancer | Renal Cell Carcinoma | Urologic Malignant Disorders | Familial Renal Cancer (FRC) | Clear Cell Renal Cancer

United States
National Cancer Institute (NCI)

Completed

Study of Disease Severity in Adults With Neurofibromatosis Type 1 (NF1)

Neurofibromatosis Type 1 | Legius Syndrome

United States
National Cancer Institute (NCI)

Enrolling by invitation

Assessing Sleep and Circadian Rhythms in Primary Brain Tumors Patients

Sleep Circadian Rhythms | Chronodisruption

United States
National Cancer Institute (NCI)

Completed

Administration of Anti-CD19-chimeric-antigen-receptor-transduced T Cells From the Original Transplant Donor to Patients With Recurrent or Persistent B-cell Malignancies After Allogeneic Stem Cell Transplantation

Lymphoma, B-Cell | Leukemia, B-cell | Lymphoma, Hodgkins | Lymphoma, Non-hodgkins

United States
National Cancer Institute (NCI)

Suspended

Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors

Neoplasms | Solid Tumors

United States
National Cancer Institute (NCI)

Enrolling by invitation

Collection of Pharmacokinetic Samples From People With Unanticipated Response, Significant Toxicity or Concern of Future Toxicity

Cancer | Solid Tumors | Neoplasm

United States
National Cancer Institute (NCI)

Suspended

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

Lymphoma | Leukemia

United States
National Cancer Institute (NCI)

Completed

NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors

Sarcoma | Neuroblastoma | Solid Tumors | Brain Tumors | Pediatric Cancers

United States
National Cancer Institute (NCI)

Active, not recruiting

Retrospective Analysis of a Drug-Metabolizing Genotype in Cancer Patients and Correlation With Pharmacokinetic and Pharmacodynamics Data

Melanoma | Breast Cancer | Lung Cancer | Prostate Cancer | Cutaneous T-Cell Lymphoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Breast Mammogram and Tissue Study

Breast Neoplasms

United States
National Cancer Institute (NCI)

Enrolling by invitation

Eligibility Screening for the NIH Intramural Research Program Clinical Protocols

Melanoma | Sarcoma | Breast Cancer | Lung Cancer | Prostate Cancer

United States
National Cancer Institute (NCI)

Completed

Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors

Urethral Neoplasms | Urethral Cancer | Neoplasms, Urethral | Cancer of the Urethra

United States
National Cancer Institute (NCI)

Completed

Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors

Ependymoma | Medulloblastoma | PNET | Diffuse Intrinsic Pontine Glioma | Germinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors

Neurofibromatosis 1 | Neurofibroma, Plexiform | Neurofibromatosis Type 1 | NF1

United States
National Cancer Institute (NCI)

Completed

Validating Pain Scales in Children and Young Adults

Leukemia | Solid Tumor | Sickle Cell Disease | Neurofibromatosis

United States
National Cancer Institute (NCI)

Completed

Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1

Neurofibromatosis | MPNST

United States
National Cancer Institute (NCI)

Active, not recruiting

Prospective Randomized Study of Cell Transfer Therapy for Metastatic Melanoma Using Tumor Infiltrating Lymphocytes Plus IL-2 Following Non-Myeloablative Lymphocyte Depleting Chemo Regimen Alone or in Conjunction With 12Gy Total Body Irradiation (TBI...

Skin Cancer | Metastatic Melanoma

United States
National Cancer Institute (NCI)

Enrolling by invitation

Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies

Breast Cancer | Ovarian Cancer | Uterine Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Esophageal Cancer in Northeastern Iran

Esophageal Cancer | GI Disease

Iran, Islamic Republic of
National Cancer Institute (NCI)

Terminated

LMB-100 Followed by Pembrolizumab in the Treatment of Adults With Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer | Lung Cancer | Adenocarcinoma of Lung

United States
National Cancer Institute (NCI)

Completed

Dasatinib in Combination With Bevacizumab to Treat Advanced Solid Tumors

Solid Tumors

United States
National Cancer Institute (NCI)

Active, not recruiting

Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell Malignancies

Follicular Lymphoma | Acute Lymphoblastic Leukemia | Acute Lymphocytic Leukemia | NHL | B-All | ALL | Large Cell Lymphoma | B-NHL | B-Non Hodgkin Lymphoma | B-precursor ALL

United States
National Cancer Institute (NCI)

Withdrawn

N-803 Alone or in Combination With BN-Brachyury Vaccine or Bintrafusp Alfa (M7824) for Participants With Castration Resistant Prostate Cancer

Castration Resistant Prostate Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Cancer

Cancer | Hereditary Neoplasms | Genetic Predisposition to Cancer | Environment

United States
National Cancer Institute (NCI)

Enrolling by invitation

Collection and Distribution of Samples From Healthy Donors for In Vitro Research at the NCI-Frederick

Healthy Donors

United States
National Cancer Institute (NCI)

Active, not recruiting

Retrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With Cancer

Macrophage Activation Syndrome | Primary Hemophagocytic Lymphohistiocytosis

United States
National Cancer Institute (NCI)

Completed

Systematically Assessing Changes in Plexiform Neurofibroma Related Disfigurement From Photographs of Subjects With Neurofibromatosis Type 1 on a Phase 2 Clinical Trial

Neurofibromatosis 1

United States
National Cancer Institute (NCI)

Active, not recruiting

Cladribine With Simultaneous or Delayed Rituximab to Treat Hairy Cell Leukemia

Hairy Cell Leukemia

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of Indenoisoquinolines LMP400 and LMP776 in Adults With Relapsed Solid Tumors and Lymphomas

Neoplasms | Lymphoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity

HIV | Lymphoproliferative Disorder | Malignancy | HHV-8

United States
National Cancer Institute (NCI)

Active, not recruiting

Examination of Clinical and Laboratory Abnormalities in Patients With Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy

Skin Neoplasms | Xeroderma Pigmentosum | Cockayne Syndrome | Trichothiodystrophy Syndromes | Genodermatosis

United States
National Cancer Institute (NCI)

Active, not recruiting

Phase II Study of Cediranib (AZD2171) in Patients With Alveolar Soft Part Sarcoma

Sarcoma, Alveolar Soft Part

United States
National Cancer Institute (NCI)

Completed

Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)

Glioblastoma

United States
National Cancer Institute (NCI)

Completed

Long-Term TARP Vaccination Using a Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Previously Vaccinated Men on NCI 09-C-0139

Prostatic Neoplasms | Prostate Cancer | Neoplasms of Prostate | Cancer Of Prostate | Stage D0 Prostate Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Early Detection of Esophageal Cancer

Stomach Neoplasms | Esophageal Neoplasms | Endoscopy, Gastrointestinal | Cytology | Digestive System Endoscopic Surgical Procedures

China
National Cancer Institute (NCI)

Active, not recruiting

Romidepsin, CC-486 (5-azacitidine), Dexamethasone, and Lenalidomide (RAdR) for Relapsed/Refractory T-cell Malignancies

Cutaneous T-Cell Lymphoma | Peripheral T-Cell Lymphoma | Mature T-cell Malignancies | Relapsed/ Refractory T-cell Malignancies

United States
National Cancer Institute (NCI)

Active, not recruiting

Combination Immunotherapy in Biochemically Recurrent Prostate Cancer

Prostate Cancer

United States
National Cancer Institute (NCI)

Completed

Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer

Familial Ovarian Cancer | Familial Breast Cancer | BRCA1-associate Malignancies | BRCA2-associated Malignancies

United States
National Cancer Institute (NCI)

Withdrawn

Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelin

Malignant Pleural Mesotheliomas (Mpm) | Malignant Pleural Effusions (Mpe) | Epithelial Tumors, Malignant | Pleural Effusions, Malignant | Mesothelin (Msln)

United States
National Cancer Institute (NCI)

Active, not recruiting

A Phase II Study of Bevacizumab and Erlotinib in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell Cancer

HLRCC | Sporadic Papillary Renal Cell Cancer

United States

Clinical Trials Sponsored by Cone Health System Cancer Center

Sponsors and Collaborators

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