Clinical Trials Sponsored by Create Marketing

Total 974 results

Reata, a wholly owned subsidiary of Biogen

Withdrawn

A Double-Blind, Randomized, Placebo-Controlled Safety Study Evaluating the Effects of Residual Renal Function (RFF) in Patients With End-Stage Renal Disease and Type 2 Diabetes Mellitus on Peritoneal Dialysis

Type 2 Diabetes Mellitus | End-Stage Renal Disease
Reata, a wholly owned subsidiary of Biogen

Completed

RTA 408 Capsules in Patients With Melanoma - REVEAL

Melanoma | Unresectable (Stage III) Melanoma | Metastatic (Stage IV) Melanoma

United States
Reata, a wholly owned subsidiary of Biogen

Completed

A Human AME Study for Omaveloxolone

Healthy Male Subjects

United States
Reata, a wholly owned subsidiary of Biogen

Completed

Multiple-Dose Study of Effect of Bardoxolone Methyl on QT/QTC Interval Volunteers

Healthy Volunteers

United States
Reata, a wholly owned subsidiary of Biogen

Completed

Phase II Pharmacodynamic Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease

Diabetes Mellitus, Type 2 | Renal Insufficiency, Chronic

United States
MetroHealth Medical Center
ResMed; Great Lakes NeuroTechnologies Inc.

Terminated

CPAP vs AutoCPAP for Treatment of Obstructive Sleep Apnea (OSA) in the Postoperative Setting

Obstructive Sleep Apnea

United States
NHS Greater Glasgow and Clyde
Fisher and Paykel Healthcare; LINET

Recruiting

High Flow Nasal Oxygen at Extubation for Adults Requiring a Breathing Tube for Treating Severe Breathing Difficulties (Pre-SAFEx)

Respiratory Insufficiency

United Kingdom
University of Glasgow
NHS Greater Glasgow and Clyde; Tenovus Scotland

Recruiting

Investigating the Long-term Cardiac Sequelae of Trastuzumab Therapy

Breast Cancer | HER2-positive Breast Cancer | Cardiotoxicity

United Kingdom
Glasgow Caledonian University
NHS Greater Glasgow and Clyde; NHS Lanarkshire

Completed

TAIC: Student-led Exercise for Older Adults at Risk of Falling (TAIC)

Exercise | Falls

United Kingdom
NHS Greater Glasgow and Clyde
Jean Brown Bequest Fund, Glasgow

Completed

3D Telemedicine During COVID-19: Cohort Study

Telemedicine | Surgery, Plastic

United Kingdom
Amy C Schefler, MD
Regeneron Pharmaceuticals

Unknown

Intravitreal Aflibercept Injection for Radiation Retinopathy Trial (ARRT)

Radiation Retinopathy

United States
Sokratis Stoumpos
NHS Greater Glasgow and Clyde

Completed

Ferumoxytol Enhanced Magnetic Resonance Angiography in Chronic Kidney Disease (FeMRA in CKD)

Kidney Transplantation | Arteriovenous Fistula | Magnetic Resonance Angiography | Ferric Compounds | Vascular Grafting

United Kingdom
David M. Brown, M.D.
Genentech, Inc.

Completed

Efficacy & Safety Trial of Intravitreal Injections Combined With PRP for CSME Secondary to Diabetes Mellitus (DAVE) (DAVE)

Diabetic Macular Edema

United States
Planned Parenthood of Greater New York
Society of Family Planning

Completed

Study of the Sensitivity of Manual vs Electric Aspiration to Detect Completed Early Abortion

Induced Abortion

United States
VA Greater Los Angeles Healthcare System
Ralph M. Parsons Foundation

Completed

A Safety/Efficacy Trial of Zonisamide for Essential Tremor

Essential Tremor

United States
Sonia Allam
NHS Greater Glasgow and Clyde

Completed

Effect Site Controlled, Reaction Time Safeguarded, Patient Maintained Sedation With Propofol in Healthy Volunteers

Healthy

United Kingdom
Reata, a wholly owned subsidiary of Biogen

Recruiting

A Phase 2 Study of RTA 901 in Patients With Diabetic Peripheral Neuropathic Pain (CYPRESS) (CYPRESS)

Diabetic Peripheral Neuropathic Pain

United States
Reata, a wholly owned subsidiary of Biogen

Completed

Effect of Itraconazole on the Pharmacokinetics of Bardoxolone Methyl in Healthy Adults

Healthy Volunteers

United States
Reata, a wholly owned subsidiary of Biogen

Completed

Safety and PK/PD of RTA 1701 in Healthy Adults

Healthy

Australia
Reata, a wholly owned subsidiary of Biogen

Completed

A Pharmacokinetic Study of Omaveloxolone in Subjects With Hepatic Impairment and Normal Hepatic Function

Hepatic Impairment

United States
Reata, a wholly owned subsidiary of Biogen

Completed

A Pharmacokinetic Study of Omaveloxolone in Healthy Volunteers

Healthy

United States
Reata, a wholly owned subsidiary of Biogen

Completed

A Single-Dose, Open-Label, Randomized, Food Effect and Blinded, Randomized, Dose Proportionality Study in Healthy Volunteers With Bardoxolone Methyl

Healthy Volunteers

United States
Reata, a wholly owned subsidiary of Biogen

Withdrawn

A Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Effects of Bardoxolone Methyl on Body Composition in Patients With Stage 4 Chronic Kidney Disease and Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2 | Renal Insufficiency, Chronic
Reata, a wholly owned subsidiary of Biogen

Terminated

Study to Assess the Safety, Tolerability, and Pharmacodynamics of RTA 402 in Patients With Hepatic Dysfunction

Liver Disease

United States
Reata, a wholly owned subsidiary of Biogen

Terminated

Bardoxolone Methyl Evaluation in Patients With Chronic Kidney Disease and Type 2 Diabetes (BEACON)

Diabetes Mellitus, Type 2 | Renal Insufficiency, Chronic
Reata, a wholly owned subsidiary of Biogen

Withdrawn

Study of Two Dose Levels of RTA 402 in Patients With Advanced Malignant Melanoma

Malignant Melanoma
Reata, a wholly owned subsidiary of Biogen

Completed

A Phase I Study to Investigate the Absorption, Metabolism and Excretion in Healthy Male Subjects

Healthy

United States
Reata, a wholly owned subsidiary of Biogen

Withdrawn

Pilot Assessment of the Effects of Bardoxolone Methyl on Renal Perfusion, Systemic Haemodynamics and Cardiac Function in Patients With Chronic Kidney Disease and Type 2 Diabetes

Diabetes Mellitus, Type 2 | Renal Insufficiency, Chronic
Reata, a wholly owned subsidiary of Biogen

Completed

Single-Dose, Open-Label Pharmacokinetic Study of Bardoxolone Methyl in Subjects With Mild, Moderate, and Severe Hepatic Impairment and Normal Hepatic Function

Healthy | Hepatic Impairment

United States
NHS Greater Glasgow and Clyde
University of Strathclyde; Microsoft Corporation

Not yet recruiting

Clinical Trial of 3D Telemedicine

Surgery | Telemedicine

United Kingdom
NHS Greater Glasgow and Clyde
University of Glasgow; Lancaster University

Recruiting

BEAT-IT: Behavioural Activation and Severe Learning Disabilities

Depression

United Kingdom
NHS Greater Glasgow and Clyde
The Glasgow School of Art

Recruiting

Augmented Reality (AR): The Future of "Patient Information Leaflets

Sarcoma | Breast Cancer | Cleft Lip and Palate | Surgical Flap

United Kingdom
NHS Greater Glasgow and Clyde
University of Strathclyde; Microsoft Corporation

Completed

3D Telemedicine: A Clinician Feedback Study

Telemedicine | Reconstructive Surgery | 3 Dimensional

United Kingdom
Emory University
Center for Creative Initiatives in Health and Population

Completed

Preventing Sexual Violence in College Men: RealConsent for Use in Vietnam

Sexual Violence

Vietnam
Planned Parenthood of Greater New York
Society of Family Planning

Completed

Laminaria Compared to Dilapan-S for Cervical Preparation Before Dilation and Evacuation at 18-24 Weeks of Gestation

Second Trimester Abortion

United States
University of Edinburgh
NHS Lothian; NHS Greater Glasgow and Clyde

Unknown

High-Sensitivity Cardiac Troponin On Presentation to Rule Out Myocardial Infarction (HiSTORIC)

Myocardial Infarction | Acute Coronary Syndrome
Columbia University
Locks of Love; Alopecia Areata Initiative - Gates Foundation

Completed

Pilot Study to Evaluate the Efficacy of Ruxolitinib in Alopecia Areata

Alopecia Areata

United States
David M. Brown, M.D.
Regeneron Pharmaceuticals

Completed

Study for Recalcitrant Age Related Macular Degeneration (TURF)

Age Related Macular Degeneration

United States
David M. Brown, M.D.
Genentech, Inc.

Terminated

A Study of Intravitreal Injections of 2.0mg Ranibizumab in Subjects With Chronic Fluid On OCT Post Multiple Injections With Ranibizumab (Super-dose Anti-VEgf SAVE Trial) (SAVE)

Macular Degeneration | Age Related Macular Degeneration | Wet Age-Related Macular Degeneration | Choroidal Neovascular Membrane | Subfoveal Neovascular Age-Related Macular Degeneration

United States
Rachel Kearns
NHS Greater Glasgow and Clyde

Completed

Study Comparing a Nerve Block With Spinal Opiate to Provide Pain Relief for Hip Replacement Surgery

Analgesia

United Kingdom
Reata, a wholly owned subsidiary of Biogen

Terminated

A Trial of Bardoxolone Methyl in Patients With ADPKD - FALCON (FALCON)

Autosomal Dominant Polycystic Kidney | ADPKD

United States, Spain, United Kingdom, Australia, France, Japan, Germany, Belgium, Czechia, Italy
Reata, a wholly owned subsidiary of Biogen

Terminated

Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension - CATALYST

Connective Tissue Disease-Associated Pulmonary Arterial Hypertension

United States, Spain, Japan, Australia, United Kingdom, Canada, Germany, Belgium, Argentina, Israel, Mexico, Brazil, Czechia, Netherlands, Philippines
Reata, a wholly owned subsidiary of Biogen

Terminated

Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER (RANGER)

Pulmonary Hypertension

United States, Spain, Australia, United Kingdom, Canada, Belgium, Argentina, Israel, Japan, Philippines, Germany, Mexico, Brazil, Czechia, Netherlands
Reata, a wholly owned subsidiary of Biogen

Completed

A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX (PHOENIX)

Focal Segmental Glomerulosclerosis | IgA Nephropathy | Autosomal Dominant Polycystic Kidney | CKD Associated With Type 1 Diabetes

United States
Reata, a wholly owned subsidiary of Biogen

Completed

A Trial of Bardoxolone Methyl in Patients With CKD at Risk of Rapid Progression (MERLIN) (MERLIN)

Chronic Kidney Diseases

United States
Reata, a wholly owned subsidiary of Biogen

Completed

Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT

Idiopathic Pulmonary Fibrosis | Pulmonary Arterial Hypertension | Pulmonary Hypertension | Interstitial Lung Disease | Sarcoidosis | Idiopathic Interstitial Pneumonia | Cryptogenic Organizing Pneumonia | Desquamative Interstitial Pneumonia | Respiratory Bronchiolitis Associated Interstitial Lung Disease and other conditions

United States, Germany
Reata, a wholly owned subsidiary of Biogen

Terminated

RTA 744 in Breast Cancer Patients With Progression of Previously Irradiated Brain Metastases

Brain Metastases

United States
Reata, a wholly owned subsidiary of Biogen

Completed

A Safety Study of RTA 744 in Patients With Recurrent High-Grade Gliomas

Glioma

United States
Reata, a wholly owned subsidiary of Biogen

Terminated

Pharmacokinetic and Pharmacodynamic Study of Bardoxolone Methyl in Patients With Chronic Kidney Disease and Type 2 Diabetes

Diabetes Mellitus, Type 2 | Renal Insufficiency, Chronic
Reata, a wholly owned subsidiary of Biogen

Completed

A Phase 2/3 Trial of the Efficacy and Safety of Bardoxolone Methyl in Patients With Alport Syndrome - CARDINAL (CARDINAL)

Alport Syndrome

United States, United Kingdom, Japan, Australia, France, Germany, Puerto Rico, Spain

Clinical Trials Sponsored by Create Marketing

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