Clinical Trials Sponsored by Diacon Hospital

Total 100676 results

Medios Technologies Pte. Ltd
Diacon Hospital

Unknown

Simple, Mobile-based Artificial Intelligence AlgoRithms in the Detection of Diabetic ReTinopathy (SMART) Study (SMART)

Diabetic Retinopathy

India
Viacor

Completed

Aachen Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Device to Reduce Mitral Regurgitation (PTOLEMY)

Heart Failure | Mitral Regurgitation

Germany
Viacor

Completed

Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Device to Reduce Mitral Regurgitation (PTOLEMY)

Heart Failure | Mitral Regurgitation

Germany
Viacor

Completed

Montreal Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Device (PTOLEMY)

Heart Failure | Mitral Regurgitation

Canada
Biocon Biologics UK Ltd

Active, not recruiting

Comparison of Efficacy, Pharmacodynamics, Safety, and Immunogenicity Between Bmab 1000 and Prolia® in Postmenopausal Women With Osteoporosis (DEVOTE)

Postmenopausal Women With Osteoporosis

United Kingdom
Beacon Therapeutics

Recruiting

A Clinical Trial Evaluating the Safety and Efficacy of a Single Subretinal Injection of AGTC-501 in Participants With XLRP

X-Linked Retinitis Pigmentosa

United States
Ersta Diakoni
Göteborg University; Sundsvall Hospital

Recruiting

Gastropexy in the Repair of Patients With Paraesophageal Hernias (PEH3)

Paraesophageal Hernia

Sweden
Biocon Biologics UK Ltd

Not yet recruiting

Efficacy and Safety of the Proposed Biosimilar Pertuzumab (PERT-IJS) Versus EU-Perjeta® Along With Trastuzumab and Chemotherapy (Carboplatin and Docetaxel) as Neoadjuvant Treatment in Chemotherapy naïve Patients With Early Stage or Locally Advanced HR Negative and HER2 Positive Breast Cancer

HR Negative HER2 Positive Early Breast Cancer or Locally Advanced Breast Cancer Patients
Biocon Biologics UK Ltd

Active, not recruiting

Comparing Efficacy and Safety of Bmab 1200 and Stelara in Patients With Moderate to Severe Chronic Plaque Psoriasis (STELLAR-2)

Moderate to Severe Chronic Plaque Psoriasis

United States
Beacon Therapeutics

Active, not recruiting

A Study Comparing Two Doses of AGTC-501 in Male Subjects With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (SKYLINE)

X-Linked Retinitis Pigmentosa

United States
Beacon Therapeutics

Enrolling by invitation

A Study Comparing Two Doses of AGTC-501 in Male Participants With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (DAWN)

X-Linked Retinitis Pigmentosa

United States
Beacon Therapeutics

Active, not recruiting

Safety and Efficacy of rAAV2tYF-GRK1-RPGR in Subjects With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (HORIZON)

X-Linked Retinitis Pigmentosa

United States
Biocon Limited

Completed

Efficacy and Safety of Itolizumab in COVID-19 Complications

Covid19 | Acute Respiratory Distress Syndrome | Cytokine Release Syndrome

India
Biocon Limited

Completed

Comparison of Insulin Tregopil (IN-105) With Insulin Aspart in Type 2 Diabetes Mellitus Patients

Type2 Diabetes Mellitus

India
Biocon Limited

Completed

Effect of Dosing Time and Meal on IN-105 (Insulin Tregopil) PK and PD

Type 2 Diabetes Mellitus
Biocon Limited

Terminated

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Insulin (IN-105) in Type 1 Diabetes Patients

Type 1 Diabetes Mellitus

India
Diakron Pharmaceuticals

Completed

A Healthy Volunteer Study to Evaluate for a Single Dose of 4 Different Tablets of DPOC-4088 the Absorption and Elimination From the Body and the Potential Effect on Blood Clotting

Deep Vein Thrombosis Leg

Belgium
Placon Therapeutics

Unknown

A Study to Determine the Safety of BTP-114 for Treatment in Patients With Advanced Solid Tumors With BRCA Mutations

Breast Neoplasms | Prostatic Neoplasms | Pancreatic Neoplasms | Ovarian Neoplasms

United States
Deacon Biosciences, Inc.
ORA, Inc.

Completed

A Phase 2, Open-Label, Randomized, Parallel Group, Placebo-Controlled, Single-Center Study to Assess Anti-microbial Efficacy and Safety of DCN01 Compared to Unisol® Following Topical Periocular Administration in Healthy Volunteers

Ocular Infection

United States
Biocon Biologics UK Ltd
Biotrial

Completed

Comparison of Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Bmab 1000 and Prolia® in Normal Healthy Volunteers: DENARIUS: DENosumab Pharmacokinetic equivAlence tRIal in Healthy volUnteerS (DENARIUS)

Healthy Volunteers

United States
Universiti Putra Malaysia
Beacon Hospital Sdn Bhd

Not yet recruiting

The Role of Plant-Based Omega-3 Fatty Acids and Molecular Characterisation in Individuals With Cardiovascular(CVD) Risk

Cardiovascular Risk

Malaysia
Iacob Czihac Emergency Military Clinical Hospital

Completed

Risk Factor Involved in Knee Osteoarthritis (KOA)

Knee Osteoarthritis

Romania
Tracon Pharmaceuticals Inc.

Active, not recruiting

YH001 Plus Envafolimab With or Without Doxorubicin in Patients With Advanced or Metastatic Sarcoma

Soft Tissue Sarcoma | Advanced Sarcoma | Metastatic Sarcoma

United States
Epividian
Theratechnologies; FIECON

Completed

External Comparison of Ibalizumab in Trials vs. Other Regimens in OPERA

HIV-1-infection

United States
Tracon Pharmaceuticals Inc.

No longer available

Open Label Continuation Study of TRC105 for Patients Who Have Completed a Prior TRC105 Trial

Solid Tumors

United States
Tracon Pharmaceuticals Inc.

Completed

Study of TRC102 in Combination With Pemetrexed in Cancer Patients

Neoplasm

United States
Equillium
Biocon Limited

Recruiting

A Study of Itolizumab in Combination With Corticosteroids for the First-Line Treatment of Acute Graft Versus Host Disease (EQUATOR)

Graft Versus Host Disease | GVHD | aGVHD | Acute-graft-versus-host Disease | Acute GVHD

United States, Korea, Republic of, Israel, Spain, Germany, Belgium, Italy, Australia, France, Canada, Portugal
Tracon Pharmaceuticals Inc.

Recruiting

ENVASARC: Envafolimab And Envafolimab With Ipilimumab In Patients With Undifferentiated Pleomorphic Sarcoma Or Myxofibrosarcoma (ENVASARC)

Undifferentiated Pleomorphic Sarcoma | Myxofibrosarcoma

United States, United Kingdom
Dialco Medical Inc.

Withdrawn

The Evaluation of the DIMI RRT System In-Center to Demonstrate Safety and Usability in the Home Environment

Hemodialysis | ESRD
Diamond Headache Clinic

Terminated

Tandem OnabotulinumtoxinA Galcanezumab Emerging Therapeutic Headache Elimination Research Study (TOGETHER)

Migraine

United States
Dracen Pharmaceuticals, Inc.

Terminated

Study to Investigate DRP-104 in Adults With Advanced Solid Tumors

Advanced Solid Tumor | Non Small Cell Lung Cancer Metastatic

United States, Taiwan, Germany, Singapore, Spain
Equillium
Biocon Limited

Withdrawn

A Study to Evaluate the Efficacy and Safety of Itolizumab in Subjects Hospitalized With COVID-19 (EQUINOX)

Coronavirus

Colombia
Tracon Pharmaceuticals Inc.

Terminated

Randomized Phase 2 Trial of Axitinib and TRC105 Versus Axitinib Alone in Patients Renal Cell Carcinoma

Renal Cell Carcinoma

United States, Hungary, Czechia, United Kingdom
Tracon Pharmaceuticals Inc.

Completed

Trial of TRC105 and Pazopanib Versus Pazopanib Alone in Patients With Advanced Angiosarcoma (TAPPAS)

Advanced Angiosarcoma

United States, France, Italy, Austria, Germany, Poland, Spain, United Kingdom
Tracon Pharmaceuticals Inc.

Completed

TRC105 Combined With Standard-dose Bevacizumab for Two Patients With Metastatic And Refractory Choriocarcinoma

Choriocarcinoma

United States
Tracon Pharmaceuticals Inc.

Completed

Open Label Phase 1 Dose Finding Study of TRC105 in Patients With Solid Cancer

Cancer | Neoplasm Metastasis

United States
Tracon Pharmaceuticals Inc.

Completed

Phase 1, Open-label, Dose Escalation Study of TRC093, in Patients With Locally Advanced or Metastatic Solid Tumors

Cancer | Neoplasm Metastasis

United States
Equillium
Biocon Limited

Recruiting

A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD (EQUATE)

GVHD | GVHD, Acute | aGVHD | Acute-graft-versus-host Disease

United States
Equillium
Biocon Limited

Completed

Study of EQ001 (Itolizumab) in Systemic Lupus Erythematosus With or Without Active Proliferative Nephritis (EQUALISE)

Lupus Nephritis | Lupus Erythematosus

United States, India, Poland
Tracon Pharmaceuticals Inc.

Active, not recruiting

Study of TJ004309 in Combination With Atezolizumab (Tecentriq®) in Patients With Advanced or Metastatic Cancer

Solid Tumor | Metastatic Cancer

United States
Tracon Pharmaceuticals Inc.

Completed

Trial of TRC105 and Sorafenib in Patients With HCC

Hepatocellular Carcinoma

United States
Tracon Pharmaceuticals Inc.

Completed

Study of Carotuximab (TRC105) Plus Nivolumab in Patients With Metastatic NSCLC

Carcinoma, Non-Small-Cell Lung

United States
Tracon Pharmaceuticals Inc.

Completed

A Phase 1B Dose-escalation and Phase 2a Study of Carotuximab (TRC105) in Combination With Pazopanib in Patients With Advanced Soft Tissue Sarcoma

Advanced Soft Tissue Sarcoma

United States
Tracon Pharmaceuticals Inc.

Terminated

Study of TRC105 and Bevacizumab in Patients With Refractory Gestational Trophoblastic Neoplasia (GTN)

Gestational Trophoblastic Neoplasia | Choriocarcinoma | Placental Site Trophoblastic Tumor | Epithelioid Trophoblastic Tumor

United States
Tracon Pharmaceuticals Inc.

Completed

Evaluation of TRC105 in the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma

Fallopian Tube Carcinoma | Primary Peritoneal Carcinoma | Recurrent Ovarian Cancer

United States
Tracon Pharmaceuticals Inc.

Completed

Study of TRC105 Combined With Standard-Dose Bevacizumab for Advanced Solid Tumors for Which Bevacizumab is Indicated

Adult Solid Tumor

United States
Dicot AB

Active, not recruiting

A Phase 1 Trial of LIB-01 in Healthy Participants.

Erectile Dysfunction

Sweden
Fondation Hôpital Saint-Joseph
Centre Hospitalier Universitaire Dijon; St Vincent's Hospital, Sydney; Hopital...

Active, not recruiting

UltraSound for Accurate Decisions in Chest PhysioTherapy (US-ADEPT)

Critical Illness | Respiratory Disease

France, Australia
Beacon Health System
Beacon Health Foundation; Coach Me Health

Active, not recruiting

Pilot of Virtual Health Coaching Utilizing Lifestyle for Under-Resourced Patients With Type II Diabetes

Type2 Diabetes

United States
PulseAI Ltd
Beacon Hospital Research Institute, Dublin, Ireland

Recruiting

Automated Diagnostic Performance of Smartwatch ECG for Arrhythmia Detection Using the PulseAI Neural Network.

Arrhythmias, Cardiac

Ireland

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