Clinical Trials Sponsored by Great Ormond Street Hospital Charity

Total 138 results

Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Improving Phosphate Control in Children With CKD (IMPACT)

Chronic Kidney Diseases | Hyperphosphatemia | Chronic Kidney Disease-Mineral and Bone Disorder | Pediatric Kidney Disease | CKD-MBD

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

90Y-labelled Anti-CD66 ab in Childhood High Risk Leukaemia (RITII)

Leukemia

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Methods of Providing Information Prior to an Alveolar Bone Graft

Cleft Lip and Palate

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Correlation of Nasopharyngeal (NP) and Lower Oesophageal (LO) Temperatures in Ventilated Children

Child

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Differences in Access to Emergency Paediatric Intensive Care and Care During Transport (DEPICT)

Access and Transport to Paediatric Intensive Care

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Terminated

Therapeutic Controlled Hypothermia in the Treatment of Neonates With Severe Necrotizing Enterocolitis (CoolNEC)

Necrotizing Enterocolitis

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Withdrawn

Investigating Prevalence of Disordered Eating in Children With GI Disorders

Disordered Eating

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Advanced MRI for Posterior Fossa Tumours

Cerebellar Mutism | Posterior Fossa Syndrome

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Terminated

Measuring the Metabolic Cost of Fever (IGUANA)

Critical Illness | Child | Fever
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Yttrium-90 Anti CD66 Monoclonal Antibody in Childhood Relapsed/Refractory Leukaemia

Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Acute Myeloblastic Leukemia

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Unknown

Role of Immune and Inflammatory Response in Recipients of Allogeneic Haematopoietic Stem Cell Transplantation (SCT) Affected by Severe COVID19 ((COVID19_BMT))

COVID19

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Unknown

The Management of Systemic-Pulmonary Collateral Blood Flow in Cyanotic Children During Cardiopulmonary Bypass - Pilot Study

Heart Defects, Congenital

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Gene Therapy ADA Deficiency

Adenosine Deaminase Deficiency

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Infant and Child European Cryoablation Project ICECaP

Therapy | Pediatric | Cryoablation | Soft Tissue Lesion

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Lentiviral Gene Therapy for X-linked Severe Combined Immunodeficiency

Severe Combined Immunodeficiency, X-Linked

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Gait Analysis in Idiopathic Clubfoot Patients Treated by the Ponseti Method

Congenital Talipes Equino Varus

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

How Easy is it to Identify the Cricothyroid Membrane in Children? Can Ultrasound Imagine be Used to Aid Identification?

Cricothyroidotomy

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Withdrawn

Pathophysiology of Dilated Cardiomyopathy

Dilated Cardiomyopathy

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Characteristics and Outcomes of Childhood Moyamoya in the UK

Moyamoya

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

INSPIRE-CF: an Alternative Physiotherapy Model for Children With Cystic Fibrosis (INSPIRE-CF)

Cystic Fibrosis

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Unknown

Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID-X1)

X-linked Severe Combined Immunodeficiency

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

The iStep Study: Development and Validation of an Incremental Exercise Step Test for Children With Cystic Fibrosis

Cystic Fibrosis

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Quality of Postoperative Recovery in Children and Young People

Quality of Recovery
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Blood Propofol Concentrations in Children During Spinal Surgery

Idiopathic Scoliosis | Spine Deformities | Neuromuscular Dystrophy

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Unknown

Outcome Study of Endoscopically Inserted Gastrostomy (PEG)Versus Radiologically-guided Insertion of Gastrostomy (RIG)in Children (PEG Vs RIG)

Two Interventions (PEG and RIG) Compared Against Each Other

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Not yet recruiting

First-in-human Experience Using Novel Ultraflexible Low-impedance Electrode Arrays: an IDEAL Stage 1 Study

Epilepsy | Focal Cortical Dysplasia

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Lentiviral Gene Therapy for p47 AR-CGD

P47-Phox, Deficiency of

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

MELD as an Adjunct for SEEG Trajectories (MAST)

Epilepsy | Epilepsy, Focal | Epilepsy, Refractory

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Improving Standards of Care and Translational Research in Spinal Muscular Atrophy (SMA) (SMA-REACH)

Spinal Muscular Atrophy

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

COVID-19 Staff Testing of Antibody Responses Study (Co-Stars) (Co-Stars)

SARS-CoV-2 Infection

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Open or Keyhole Surgery Through the Chest for Newborn Babies: Effect on Blood Gases (CO2)

Congenital Diaphragmatic Hernia | Esophageal Atresia With Tracheo-esophageal Fistula

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Newborn Screening for Spinal Muscular Atrophy (SMA) - a Proof of Principle Study Using Anonymised Blood Spots.

Spinal Muscular Atrophy

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Monitor Faecal Calprotectin Concentration in Infants With Heart Defects

Calprotectin | Cyanotic Heart Disease

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Suspended

NIRS to Evaluate Haemodynamic Reserve in Paediatric Moyamoya (NIRS moyamoya)

Moyamoya

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Prevalence of Autistic Spectrum Disorder (ASD) in Children With Haemophilia

Autism Spectrum Disorder | Attention Deficit Hyperactivity Disorder | Social Communication Disorder | Haemophilia
Great Ormond Street Hospital for Children NHS Foundation...

Active, not recruiting

Novel Network Analysis of Intracranial Stereoelectroencephalography (NNAIS)

Epilepsies, Partial | Intractable Epilepsy | Focal Epilepsy | Refractory Epilepsy | Epilepsy Intractable | Epilepsy in Children | Epilepsy, Focal

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Unknown

Haemodiafiltration vs Conventional Haemodialysis in Children (3H)

Children | Haemodialysis | Haemodiafiltration

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Kidney Transplant Monitoring Using Near Infra-red Spectroscopy

Kidney Transplant; Complications

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Unknown

Gene Therapy for Netherton Syndrome

Netherton Syndrome

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Completed

A Trial of Autologous Bone Marrow Derived Stem Cells in Paediatric Heart Failure

Dilated Cardiomyopathy
Great Ormond Street Hospital for Children NHS Foundation...

Terminated

Suicide Gene Therapy Trial

Haploidentical Stem Cell Transplantation

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Withdrawn

Lentiviral Gene Therapy for X-Linked Chronic Granulomatous Disease (X-CGD)

Granulomatous Disease, Chronic, X-linked, Variant

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
Medical Research Council; UCL Great Ormond Street Institute of Child Health

Recruiting

Base Edited CAR7 T Cells to Treat T Cell Malignancies (TvT CAR7) (TvT CAR7)

Relapsed/Refractory T-cell Acute Lymphoid Leukaemia

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
GOSHCC

Completed

Measuring Normal and Impaired Walking in Children Using the GAITRite Walkway

Typically Developing Children | Talipes Equino Varus | Paediatric Orthopaedic | Paediatric Neurological

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
AstraZeneca

Completed

Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours (INSPECT)

Neurofibromatosis Type 1 | Optic Nerve Glioma | Plexiform Neurofibroma

United Kingdom
Nestlé
Great Ormond Street Hospital for Children NHS Foundation Trust

Completed

Study in Children Who Have Switched to Isosource Junior Mix Formula

Cerebral Palsy

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
Wellcome Trust

Recruiting

Base Edited CAR T Cells Against AML: Deep Conditioning Ahead of Allogeneic Stem Cell Transplantation (CARAML)

Relapsed Acute Myeloid Leukaemia

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
Orchard Therapeutics

Completed

Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID

Severe Combined Immunodeficiency Due to ADA Deficiency

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
Orchard Therapeutics

Completed

Lentiviral (LV) Gene Therapy for Adenosine Deaminase (ADA) Deficiency

Adenosine Deaminase Deficiency | Severe Combined Immunodeficiencies (SCID)

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
University College, London

Not yet recruiting

Optical Coherence Tomography Angiography (OCTA) in Children's Cardiac Surgery (OCTA)

Congenital Heart Disease | Children, Only

United Kingdom

Clinical Trials Sponsored by Great Ormond Street Hospital Charity

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