Clinical Trials Sponsored by HighLife SAS

Total 11246 results

HighLife SAS

Recruiting

HighFLO Study - HighLife Trans-septal Mitral Valve Replacement (TSMVR) Feasibility Study of the Open Cell CLARITY Valve (HighFLO)

Mitral Regurgitation

Belgium, France, Poland, Germany, Australia, United Kingdom
HighLife SAS

Recruiting

An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System

Mitral Regurgitation

United States
HighLife SAS
ICON plc

Recruiting

Expanded Study of the HighLife 28mm Trans-septal Trans-catheter Mitral Valve in Patients With Moderate-severe or Severe Mitral Regurgitation and at High Surgical Risk

Mitral Regurgitation

Belgium, France, Germany, Australia, United Kingdom, Poland
HighLife SAS
MedPass International; ICON plc

Active, not recruiting

HighLife™ Transcatheter Mitral Valve Replacement System Study

Mitral Valve Insufficiency | Mitral Valve Regurgitation

France, Germany
HighTide Biopharma Pty Ltd

Completed

A Study of HTD1801 in Adults With Nonalcoholic Steatohepatitis (NASH) and Type 2 Diabetes Mellitus (T2DM)

Digestive System Diseases | NAFLD | Nonalcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis | Type 2 Diabetes Mellitus (T2DM) | Fatty Liver, Nonalcoholic

United States
HighTide Biopharma Pty Ltd

Recruiting

Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes

T2DM (Type 2 Diabetes Mellitus)

China
HighTide Biopharma Pty Ltd

Withdrawn

A Study of HTD1801 in Adolescents With Primary Sclerosing Cholangitis (PSC)

Adolescent | Digestive System Diseases | Biliary Tract Diseases | Primary Sclerosing Cholangitis | Cholangitis | Cholangitis, Sclerosing | Bile Duct Diseases
HighTide Biopharma Pty Ltd

Completed

Study of HTD4010 in Healthy Volunteers

Type 2 Diabetes Mellitus

Australia
HighTide Biopharma Pty Ltd

Completed

A Study of HTD1801 in Healthy Subjects

Primary Sclerosing Cholangitis

Australia
HighTide Biopharma Pty Ltd

Recruiting

Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

Type 2 Diabetes Mellitus

China
HighTide Biopharma Pty Ltd

Completed

Open-Label Study of HTD1801 in Adult Subjects With Primary Biliary Cholangitis (PRONTO-PBC)

Biliary Tract Diseases | Cholangitis | Cholestasis | Primary Biliary Cholangitis | Primary Biliary Cirrhosis | Bile Duct Stricture

United States
HighTide Biopharma Pty Ltd

Active, not recruiting

HTD1801 in Adults With Nonalcoholic Steatohepatitis and Liver Fibrosis Who Have Type 2 Diabetes or Pre-Diabetes (CENTRICITY)

Type 2 Diabetes | Nonalcoholic Steatohepatitis (NASH)

United States, China, Hong Kong
HighTide Biopharma Pty Ltd

Completed

A Multiple Ascending Dose Study of HTD1801 in Adults With Hypercholesterolemia

Hypercholesterolemia

Australia
HighTide Biopharma Pty Ltd

Completed

A POC and Dose-Ranging Study of HTD1801 in PSC Patients

Primary Sclerosing Cholangitis (PSC)

United States, Canada
GeNeuro Innovation SAS

Completed

Longitudinal Therapeutically Non-interventional Study of MSRV-Env Burden in Patients With Multiple Sclerosis Disease (LOMBARD)

Multiple Sclerosis (MS) | Clinically Isolated Syndrome (CIS) | Secondary Progressive MS | Primary Progressive MS | Relapsing-Remitting MS

France, Spain, Switzerland
GeNeuro Innovation SAS

Completed

Longitudinal Therapeutically Non-interventional Study of MSRV-Env Burden in Normal Population (CONTROL)

Multiple Sclerosis

France
GeNeuro Innovation SAS

Completed

First-in-Human Study With GNbAC1 in Healthy Volunteers

Multiple Sclerosis
GeNeuro Innovation SAS

Completed

Safety Study of GNbAC1 Monoclonal Antibody in Healthy Male Volunteers

Healthy Volunteers

Germany
GeNeuro Innovation SAS

Completed

Clinical Trial Assessing Temelimab Following Rituximab Treatment in Patients With Relapsing Forms of Multiple Sclerosis (ProTEct-MS)

Multiple Sclerosis

Sweden
GeNeuro Innovation SAS

Completed

Safety Study of GNbAC1 in Multiple Sclerosis Patients

Multiple Sclerosis

Switzerland
GeNeuro Innovation SAS

Terminated

A Long-term Extension of Study GNC-401

Multiple Sclerosis

Sweden
RegenLab France SAS

Recruiting

Combination of PRP and XLHA Prepared With RegenMatrix Medical Device To Treat Moderate to Severe Knee Osteoarthritis

Knee Osteoarthritis

France
Advesya SAS

Not yet recruiting

An Adaptive Open-label Multicentre Phase 1/2 Trial, to Determine the Recommended Phase 2 Dose of CCTx-001, and to Assess Safety, Tolerability, and Clinical Activity in Patients With Relapsed/Refractory Acute Myeloid Leukaemia (RESOLVE AML001)

Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory

France, Sweden, Spain, Germany
Larena SAS

Not yet recruiting

The Benefits of Dietary and Micro-nutritional Management for Well-being at Work (MEDEIS)

Well-Being, Psychological

France
Larena SAS

Recruiting

Kinetic of Compounds of a Melatonin-based Formulation in Healthy Subjects

Melatonin Bioavailability

France
Peptinov SAS

Recruiting

Dose Escalation Study Assessing the Safety and Immune Response of PPV-06 Vaccine

Knee Osteoarthritis

France
Santen SAS

Completed

Effect of IKERVIS® Eye Drops Once Daily on the Quality of Vision in Dry Eye Disease Patients With Severe Keratitis (FAST)

Keratitis

France
Larena SAS

Completed

Management of Occasional or Anticipatory Stress by Consumers of a Food Supplement (MELIM)

Stress

France
Provepharm SAS

Completed

MEthylene Blue In Patients With Acquired Methemoglobinemia (MEBIPAM)

Acquired Methaemoglobinaemia

France
Santen SAS

Active, not recruiting

A Phase III Multinational Multicenter Investigator-Masked Randomised Active-Controlled Trial Comparing the Efficacy and Safety of DE-130A With Xalatan® in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Surface Disease | Open-Angle Glaucoma or Ocular Hypertension

France
Santen SAS

Completed

Efficacy and Tolerance of Nova22007 Versus Vehicle in Patients With Vernal Keratoconjunctivitis (VKC)

Conjunctivitis, Vernal

France
Larena SAS

Completed

Effect of Lactibiane Tolerance® to Treat Leaky Gut in Irritable Bowel Syndrome With Predominant Diarrhea (IBS-D)Patients

IBS - Irritable Bowel Syndrome

Italy
DTAMedical SAS

Completed

VistaCare® in the Treatment of Wounds of the Lower Extremity

Wound Heal

France
AzurRx SAS

Completed

A Phase IIa Study With Escalating Dose of MS1819-SD

Chronic Pancreatitis | Distal Pancreatectomy

Australia, New Zealand, France
Santen SAS

Completed

NOVA22007 0.05% and 0.1% Cyclosporine Versus Vehicle for the Treatment of Dry Eye

Dry Eye

United States
Santen SAS

Completed

Safety and Tolerability of NOVA63035 "Corticosteroid" in Patients With Diabetic Macular Edema Secondary to Diabetic Retinopathy

Diabetic Macular Edema

United States
Meditor SAS

Completed

Effects of Hemoperfusion With a Polymyxin B Membrane in Peritonitis With Septic Shock (ABDO-MIX)

Septic Shock | Peritonitis

France
Santen SAS

Completed

Double-Masked Trial of NOVA22007 (Ciclosporin 0.1%) Versus Vehicle in Patients With Moderate to Severe Dry Eye Syndrome

Moderate to Severe Dry Eye Syndrome

France
Almirall, SAS

Completed

ARTIST: ARThrose Intervention STandardisée (ARTIST)

Knee Osteoarthritis

France
Gelscom SAS

Not yet recruiting

Evaluation of Efficacy and Safety of Intradiscal Gelified Ethanol in Refractory Cervical Discogenic Pain (DISCERV)

Discogenic Pain | Pain, Cervical

Italy
UroMems SAS

Recruiting

Clinical Investigation to Assess a New Artificial Urinary Sphincter to Treat Urinary Incontinence in Women (TRANSITION)

Urinary Incontinence,Stress

France
Xenothera SAS

Terminated

Efficacy and Safety of XAV-19 for the Treatment of Moderate-to-severe COVID-19

COVID-19

Spain, Bulgaria, Greece, Romania, Turkey
Santen SAS

Completed

Double-Masked Trial of NOVA22007 (1mg/mL Ciclosporin/Cyclosporine) Versus Vehicle in Pediatric Patients With Active Severe Vernal Keratoconjunctivitis

Vernal Keratoconjunctivitis

United States, Croatia, France, Germany, Greece, Hungary, India, Israel, Italy, Portugal, Spain
Alaxia SAS

Terminated

Dose Escalation Study of ALX-009 in Healthy Men and Cystic Fibrosis (CF) and Non-CF Bronchiectasis Patients

Bronchiectasis | Cystic Fibrosis

France
Santen SAS

Completed

Safety and Efficacy Study of Catioprost® (Unpreserved Latanoprost 0.005% Emulsion) Compared to Travatan Z® to Treat Glaucoma and Ocular Surface Disease

Ocular Hypertension | Glaucoma | Ocular Surface Disease

United States
Arthrex SAS

Completed

Treatment of Epicondylitis by Ultrasound-guided Local Injections of PRP (Platelet Rich Plasma)

Epicondylitis

France
Lallemand SAS

Completed

Lactobacillus Farciminis and Hyperalgesia

Pain | Inflammation

France
SAV-IOL SA
CEISO

Recruiting

Evaluation of Efficacy and Long-term Safety for Lucidis Instant Focus© - PMCF Study Protocol

Cataract

Switzerland
Maxivax SA
CATO-SMS

Withdrawn

MVX-ONCO-2 in Advanced Solid Tumors

Solid Tumor, Adult

Switzerland
Xenothera SAS

Recruiting

FIH XON7 in Advanced/Metastatic Solid Tumors (FIPO23)

Metastatic Cancer | Advanced Solid Tumor

France, Belgium

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