Clinical Trials Sponsored by Hoffmann-La Roche

Total 2457 results

Hoffmann-La Roche

Completed

A Study of the Relative Bioavailability of Single Dose RO4917838 and the Effect of Food in Healthy Volunteers

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A Study of the Effect of RO4917838 on the QTcF Interval in Healthy Volunteers

Healthy Volunteer

United States, France
Hoffmann-La Roche

Completed

A Study of RO5045337 in Patients With Liposarcomas Prior to Debulking Surgery

Sarcoma

France
Hoffmann-La Roche

Completed

An Observational Study To Assess Liver Fibrosis Stages in Patients With Chronic Hepatitis C Infection

Hepatitis C, Chronic

Brazil
Hoffmann-La Roche

Completed

A Screening Study To Assess The Cognition Status in Healthy Volunteers

Healthy Volunteer

United States, Germany, Poland
Hoffmann-La Roche

Completed

A Multiple Ascending Dose Study of R1530 in Patients With Advanced Solid Tumors.

Neoplasms

United States
Hoffmann-La Roche

Completed

A Study of the Effect of RG1662 on Metformin in Healthy Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Study of Bitopertin (RO4917838) in Healthy Male Volunteers

Healthy Volunteer

New Zealand
Hoffmann-La Roche

Completed

A Non-Interventional Study of the Occurrence Rate of Non-Small Cell Lung Cancer, Colon Cancer, Breast Cancer, Gastric Cancer and Malignant Melanoma in Turkey, and Diagnosis and Treatment Characteristics

Cancer

Turkey
Hoffmann-La Roche

Completed

A Study to Assess the Effect of Tocilizumab + Methotrexate on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis Currently on Methotrexate Therapy

Rheumatoid Arthritis

France, Germany, Italy, Australia, United States, Canada, Mexico, United Kingdom, Sweden, Belgium, Switzerland, Netherlands, Puerto Rico, Iceland
Hoffmann-La Roche

Completed

An Observational Study in Rheumatoid Arthritis Patients Treated With RoActemra/Actemra (Tocilizumab)

Rheumatoid Arthritis

Finland
Hoffmann-La Roche

Completed

A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers

Healthy Volunteer, Alzheimer's Disease

Sweden
Hoffmann-La Roche

Completed

An Observational Study of RoActemra/Actemra (Tocilizumab) in Smoking Versus Non-Smoking Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Norway, Sweden
Hoffmann-La Roche

Completed

A Study to Evaluate the Biological Activity of R1507 in Women With Operable Breast Cancer

Breast Cancer

United Kingdom
Hoffmann-La Roche

Completed

An Observational Study of Dosage Patterns in Routine Clinical Practice in Patients With Rheumatoid Arthritis (ACT-LIFE)

Rheumatoid Arthritis

Spain, United States
Hoffmann-La Roche

Completed

Local, Non-Interventional Study of RoActemra (Tocilizumab) in Poland (ACT-POL): First-Line Treatment in Routine Clinical Practice of Participants With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Poland
Hoffmann-La Roche

Completed

Ability of Muscle Imaging and Motor Function Measure (MFM) to Detect Changes in Disease Progression in Ambulant Spinal Muscular Atrophy Patients Compared to Healthy Volunteers.

Healthy Volunteer, Muscular Atrophy, Spinal

Switzerland
Hoffmann-La Roche

Completed

An Observational Study on Fatigue in Patients With Rheumatoid Arthritis Treated With RoActemra/Actemra (Tocilizumab)

Rheumatoid Arthritis

Belgium, Luxembourg
Hoffmann-La Roche

Completed

A Study on The Effect of Hepatic Impairment on The Pharmacokinetics of RO4917838

Healthy Volunteer

France, Russian Federation
Hoffmann-La Roche

Completed

A Multiple Ascending Dose Study of R4733 in Patients With Advanced Solid Tumors.

Neoplasms

United States
Hoffmann-La Roche

Completed

A Study of RO5024048 in Combination With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin) in Patients With Chronic Hepatitis C Genotype 1 or 4

Hepatitis C, Chronic

United States, Canada
Hoffmann-La Roche

Completed

A Study of Xeloda (Capecitabine) as First-Line Chemotherapy in Patients With Advanced or Metastatic Gastric Cancer.

Gastric Cancer

Taiwan
Hoffmann-La Roche

Completed

A Study of the Safety, Tolerability and Pharmacokientics of RO5545965 in Patients With Schizophrenia on Risperidone

Schizophrenia

United States
Hoffmann-La Roche

Completed

A Study of Avastin (Bevacizumab) in Combination With mFOLFOX-6 or FOLFOXIRI in Patients With Metastatic Colorectal Cancer.

Colorectal Cancer

France, Spain, Austria, United Kingdom
Hoffmann-La Roche

Completed

A Dose-Escalation Study of RO5083945 in Patients With Metastatic and/or Locally Advanced Malignant Epidermal Growth Factor Receptor (EGFR)+ Solid Tumors.

Neoplasms

Spain, France
Hoffmann-La Roche

Completed

An Observational Study of RoActemra/Actemra in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Greece
Hoffmann-La Roche

Completed

A Study of Subcutaneously Administered Tocilizumab in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Canada, New Zealand, Spain
Hoffmann-La Roche

Withdrawn

A Study of Alegitazar in Patients With Type 2 Diabetes And Chronic Kidney Disease (Alerenal Study)

Diabetes Mellitus Type 2, Kidney Disease, Chronic
Hoffmann-La Roche

Completed

Effectiveness, Safety & Nurse Management Study of MabThera SC in Patients With Non-Hodgkin's Lymphoma: Real-Life Setting

Non-Hodgkin's Lymphoma

Sweden
Hoffmann-La Roche

Completed

A Study of RO4998452 in Type 2 Diabetes Patients With Varying Degrees of Renal Impairment

Diabetes Mellitus Type 2

United States, Russian Federation
Hoffmann-La Roche

Completed

A Study of Beta-Lactam in Hospitalized Patients With Skin and Skin Structure Infections

Soft Tissue Infections

United States, Estonia, Peru, Germany, Bulgaria, South Africa, Latvia, Lithuania, Argentina, Hungary, Romania
Hoffmann-La Roche

Completed

A Study of Peginterferon Alfa-2a (Pegasys) in Participants With Hepatitis B E-Antigen (HBeAg)-Positive Chronic Hepatitis B Virus (HBV)

Hepatitis B, Chronic

China
Hoffmann-La Roche

Completed

A Safety And Pharmacokinetic Study of Setrobuvir Alone and In Combination With Ritonavir-Boosted Danoprevir in Subjects With Mild Hepatic Impairment Compared to Healthy Controls

Healthy Volunteer

Poland, Hungary
Hoffmann-La Roche

Completed

A Study of Prophylactic Treatment for Hand-Foot Syndrome in Patients Treated With Oral Xeloda (Capecitabine).

Breast Cancer

Brazil
Hoffmann-La Roche

Completed

An Observational Study on The Health Related Quality of Life in Patients With Chronic Lymphocytic Leukaemia

Lymphocytic Leukemia, Chronic

United Kingdom
Hoffmann-La Roche

Completed

A Study of Epoetin Beta (NeoRecormon) in Predialysis Patients With Renal Anemia

Anemia

Bulgaria
Hoffmann-La Roche

Completed

A Study on the Effect of Food on the Pharmacokinetics of RO5428029 in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study to Compare the Bioavailability of Copegus and Vilona® in Healthy Volunteers

Healthy Volunteer

Mexico
Hoffmann-La Roche

Completed

A Study of Subcutaneous Mircera Once Monthly in the Treatment of Anemia in Participants With Chronic Kidney Disease Not on Dialysis

Renal Anemia, Chronic

Italy, Spain, Hong Kong, Taiwan, Hungary, Korea, Republic of, Australia, Canada, France, Germany, Greece, Belgium, Thailand, Poland, Russian Federation, Israel
Hoffmann-La Roche

Completed

An Observational Study on Infusion-related Adverse Events at Administration of MabThera (Rituximab) in Patients With Chronic Lymphocytic Leukemia

Lymphocytic Leukemia, Chronic

Sweden
Hoffmann-La Roche

Completed

A Study of Trastuzumab Emtansine Versus Capecitabine + Lapatinib in Participants With HER2-positive Locally Advanced or Metastatic Breast Cancer (EMILIA)

Breast Cancer

France, Italy, Spain, Hong Kong, United States, Canada, Mexico, Denmark, Germany, Portugal, Taiwan, Switzerland, Bulgaria, Korea, Republic of, Singapore, United Kingdom, Slovenia, Bosnia and Herzegovina, Russian Federation, Br... and more
Hoffmann-La Roche

Completed

A Prospective Observational Study of Tocilizumab (RoActemra/Actemra) in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

Spain
Hoffmann-La Roche

Completed

BONCURE Study: A Study of Monthly Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis on Bisphosphonate Therapy.

Post-Menopausal Osteoporosis

Turkey, Albania, Bosnia and Herzegovina, Croatia, Macedonia, The Former Yugoslav Republic of, Serbia
Hoffmann-La Roche

Completed

A Pharmacokinetics, Pharmacodynamics and Safety Study of Warfarin in Combination With Tamiflu (Oseltamivir)

Drug Therapy, Combination

United Kingdom
Hoffmann-La Roche

Completed

An Observational Study of MabThera in Participants With Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

Greece
Hoffmann-La Roche

Completed

A Non-Interventional Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Indonesia
Hoffmann-La Roche

Completed

Use of Tocilizumab for Rheumatoid Arthritis (RA) in Daily Routine

Rheumatoid Arthritis

Germany
Hoffmann-La Roche

Completed

A Study of Trastuzumab Emtansine in Comparison With Treatment of Physician's Choice in Participants With HER2-positive Breast Cancer Who Have Received at Least Two Prior Regimens of HER2-directed Therapy (TH3RESA)

Breast Cancer

Belgium, Israel, Spain, Sweden, United States, Switzerland, Russian Federation, Czech Republic, France, Canada, Germany, Korea, Republic of, Australia, Hungary, Thailand, United Kingdom, Italy, Brazil, Slovakia, Poland, India, Norway
Hoffmann-La Roche

Completed

An Observational Study on Renal Function in Kidney Transplant Participants on Immunosuppressive Therapy Containing Mycophenolate Mofetil (ORANGE)

Kidney Transplantation

Hungary
Hoffmann-La Roche

Completed

A Study Investigating the Effect of Food and Esomeprazole on the Single Oral Dose Pharmacokinetics of Alectinib (RO5424802) in Healthy Volunteers.

Healthy Volunteer

United States

3

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