Clinical Trials Sponsored by International Trachoma Initiative

Total 101 results

Johns Hopkins University
International Trachoma Initiative

Completed

Study of Three Alternatives for Mass Treatment in Trachoma Villages of Tanzania

Trachoma

United States, Tanzania
Centre d'Appui à la lutte contre la Maladie
International Trachoma Initiative

Completed

Safety of the Co-administration of Three Drugs for Trachoma and Lymphatic Filariasis Elimination (AZIVAL)

Parasitic Diseases | Bacterial Diseases

Mali
International AIDS Vaccine Initiative

Completed

Safety and Immunogenicity of TBC-M4, a MVA HIV Vaccine Alone or in a Prime-Boost Regimen With ADVAX DNA HIV Vaccine

HIV Infections

United Kingdom
International AIDS Vaccine Initiative

Completed

A Pilot Study of Pre-Exposure Prophylaxis (PrEP) to Evaluate Safety, Acceptability, and Adherence in At-risk Populations in Uganda, Africa

HIV Infection

Uganda
International AIDS Vaccine Initiative

Completed

A Pilot Study of Pre-Exposure Prophylaxis (PrEP) to Evaluate Safety, Acceptability, and Adherence in At-Risk Populations in Kenya, Africa

HIV Infections

Kenya
International AIDS Vaccine Initiative

Completed

A Phase I Trial to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer Vaccine, Adjuvanted

HIV/AIDS

United States
International AIDS Vaccine Initiative

Completed

Safety and Immunogenicity Study of SeV-G(NP) HIV Vaccine Administered Intranasally and Ad35-GRIN HIV Vaccine Given Intramuscularly in Prime-Boost Regimens in HIV-Uninfected Volunteers

HIV Infections

United Kingdom, Kenya, Rwanda
International AIDS Vaccine Initiative
GlaxoSmithKline

Completed

Safety and Immunogenicity Study of 2 Investigational Preventive HIV Vaccines

HIV Infections

Kenya, Zambia, Uganda
International AIDS Vaccine Initiative
Targeted Genetics Corporation

Completed

Safety and Immunogenicity Study of tgAAC09, an HIV Vaccine in an Adeno-associated Virus (AAV) Capsid (TGC14F)

HIV Infections | Human Immunodeficiency Virus Infections

Uganda, South Africa, Zambia
CMV Research Foundation
International AIDS Vaccine Initiative

Completed

Safety Study of Four Chimera Cytomegalovirus (CMV) Vaccines in Healthy Adult Males 30-50 Years of Age

Cytomegalovirus

United States
International AIDS Vaccine Initiative
University of Rochester

Completed

A Trial to Evaluate Ad35-GRIN/ENV HIV Vaccine in Healthy Adult Volunteers

HIV Infections | HIV

United States
International AIDS Vaccine Initiative
Biofabri, S.L; South African Tuberculosis Vaccine Initiative; Universidad de...

Completed

MTBVAC Study in Adults With and Without Latent Tuberculosis Infection in South Africa (A-050)

Tuberculosis

South Africa
International AIDS Vaccine Initiative
Universidad de Zaragoza; Biofabri, SLU

Not yet recruiting

A Study to Evaluate the Efficacy, Safety and Immunogenicity of MTBVAC in IGRA Positive Adolescents and Adults Living in a TB Endemic Region.

Tuberculosis (TB)
International AIDS Vaccine Initiative
Coalition for Epidemic Preparedness Innovations

Recruiting

A Lassa Fever Vaccine Trial in Adults and Children Residing in West Africa

Lassa Fever

Ghana, Liberia, Nigeria
University of California, Davis
Helen Keller International; Micronutrient Initiative

Completed

Assessment of the Nutritional Status of Pregnant Women and Optimization of Prenatal Care Services

Pregnancy

Niger
International AIDS Vaccine Initiative
Biomedical Advanced Research and Development Authority

Active, not recruiting

Evaluation of Safety and Immunogenicity of rVSVΔG-SEBOV-GP Vaccine in Adults With Good General Health

Ebola Sudan Virus Disease

United States
MRC/UVRI and LSHTM Uganda Research Unit
International AIDS Vaccine Initiative

Recruiting

Feasibility of Identifying, Enrolling and Following Acute and Early HIV-1 Infected Individuals. (KILGORIS)

Acute Human Immunodeficiency Virus Type I Infection

Uganda
International AIDS Vaccine Initiative
Auro Vaccines LLC; Ichor Medical Systems Incorporated

Completed

Safety and Immunogenicity Study of HIV-MAG Vaccine +/- IL-12 and Ad35-GRIN/ENV in HIV-uninfected Volunteers

HIV Infections

Rwanda, Uganda, Kenya
International AIDS Vaccine Initiative
University of Nairobi; Medical Research Council-Oxford

Completed

A Phase IIA Trial to Evaluate the Safety and Immunogenicity of a DNA HIV-1 Vaccine Followed by an MVA HIV-1 Vaccine in HIV-uninfected Volunteers

HIV Infections

United Kingdom, Kenya
Emory University
International AIDS Vaccine Initiative; Zambia-Emory HIV Research Project

Completed

Zambia SiVET MMR Tdap-IPV (SiVET)

High Risk for HIV

Zambia
International Food Policy Research Institute
Cornell University; World Vision; Micronutrient Initiative

Completed

Feasibility and Effectiveness of Distributing Micronutrient Sprinkles to Reduce Prevalence of Anemia

Anemia

Haiti
International AIDS Vaccine Initiative
Beth Israel Deaconess Medical Center; University of Rochester

Completed

Trial of the Safety and Immunogenicity of an Oral, Replicating Ad26 Vectored HIV-1 Vaccine

HIV

United States
International AIDS Vaccine Initiative
University of Rochester; Aaron Diamond AIDS Research Center

Completed

Safety and Immunogenicity of a Modified Vaccinia Ankara (MVA) HIV Vaccine in HIV Uninfected Adults

HIV Infection

United States
National Institute of Allergy and Infectious Diseases...
International AIDS Vaccine Initiative

Withdrawn

Safety of and Immune Response to an HIV DNA Plasmid Vaccine Followed by HIV Adenoviral Vector Vaccine in Healthy African Adults

HIV Infections
International AIDS Vaccine Initiative
University of Rochester; Aaron Diamond AIDS Research Center

Completed

Safety and Immunogenicity of a Plasmid HIV Vaccine in HIV Uninfected Adults (C001)

HIV Infection

United States
Harvard School of Public Health (HSPH)
International Initiative for Impact Evaluation; Uganda Health Marketing Group; International Research Consortium

Completed

Impact of HIV Self-testing Among Female Sex Workers in Kampala, Uganda (HSPOT)

HIV Infection
International AIDS Vaccine Initiative
Brigham and Women's Hospital; Fred Hutchinson Cancer Center; Rockefeller University

Active, not recruiting

Safety and Pharmacokinetics of the Combination Broadly Neutralizing Antibodies, 3BNC117-LS-J and 10-1074-LS-J, in Healthy American and African Adults

HIV-1-infection

United States, Uganda, Kenya, Rwanda, South Africa
International AIDS Vaccine Initiative
GlaxoSmithKline; George Washington University; Amsterdam UMC, location VUmc; Rockefeller...

Active, not recruiting

A Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Protein BG505 SOSIP.GT1.1 gp140 Vaccine, Adjuvanted in Healthy, HIV-uninfected Adults

HIV Infections

United States, Netherlands
International AIDS Vaccine Initiative
Children's Hospital of Philadelphia; Nationwide Children's Hospital; Targeted...

Completed

Safety and Immunogenicity Study of tgAAC09, a Gag-PR-RT AAV HIV Vaccine (A001)

HIV Infection

Belgium, Germany, India
International AIDS Vaccine Initiative
3M; Polymun Scientific GmbH; Access to Advanced Health Institute (AAHI)

Not yet recruiting

A Study to Evaluate the Safety and Immunogenicity of 2 Doses of 100µg BG505 SOSIP.664 gp140 Vaccine, Adjuvanted, Given to a Population of Adults Who Have Received 3 Doses of 300µg BG505 SOSIP.GT1.1 gp140 Vaccine, Adjuvanted

Hiv

Netherlands
Harvard School of Public Health (HSPH)
John Snow, Inc.; International Initiative for Impact Evaluation

Completed

Zambian Peer-Educators for HIV Self-Testing Study (ZEST)

HIV Infection

Zambia
International AIDS Vaccine Initiative
ModernaTX, Inc.; AURUM Tembisa Clinical Research; Center for Family Health Research

Active, not recruiting

A Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644)

HIV-1-infection

Rwanda, South Africa
Clinton Health Access Initiative Inc.
Department for International Development, United Kingdom; Ministry of Health...

Completed

Impact of the Safe Childbirth Checklist in Luapula Province of Zambia Province of Zambia

Maternal Death | Newborn Death

Zambia
Duke University
Stanford University; Department for International Development, United Kingdom; International Initiative for Impact Evaluation and other collaborators

Completed

Improving Maternal and Child Health in India: Evaluating Demand and Supply Side Strategies (IMATCHINE) (IMATCHINE)

Sepsis | Obstetric Labor Complications | Pre-eclampsia | Neonatal Mortality | Post-partum Hemorrhage

India
Harvard School of Public Health (HSPH)
Management and Development for Health; International Initiative for Impact...

Completed

The Impact of Home Delivery of Antiretroviral Therapy on Virological Suppression

HIV | Community Health Workers | Antiretroviral Therapy, Highly Active

Tanzania
International AIDS Vaccine Initiative
National Institute of Allergy and Infectious Diseases (NIAID); Children's Hospital...

Unknown

A Phase 1, Randomized, Blinded, Dose-escalation Study of rAAV1-PG9DP Recombinant AAV Vector Coding for PG9 Antibody in Healthy Male Adults.

HIV Infections

United Kingdom
EuroVacc Foundation
Centre Hospitalier Universitaire Vaudois; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Completed

Evaluation of the Effect of Late Boost on HIV-uninfected Vaccines From EV06 Trial

HIV/AIDS

Uganda
International AIDS Vaccine Initiative
Massachusetts General Hospital; GlaxoSmithKline; Fred Hutchinson Cancer Research... and other collaborators

Completed

A Randomized, Double-blinded, Placebo-controlled, Dose-escalation Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV Envelope Protein BG505 SOSIP.664 gp140 Vaccine, Adjuvanted, in Healthy, HIV-1 Uninfected Adults

HIV Infections

United States, Kenya
David Ho
Bill and Melinda Gates Foundation; International AIDS Vaccine Initiative; The...

Completed

10E8.4/iMab Bispecific Antibody in HIV-uninfected and HIV-infected Adults

HIV-1-infection

United States
The Hospital for Sick Children
International Centre for Diarrhoeal Disease Research, Bangladesh; The Sprinkles...

Completed

Delivery Vehicles for Prenatal Calcium Supplementation

Pregnancy

Canada, Bangladesh
University of British Columbia
Canadian Institutes of Health Research (CIHR); Helen Keller International; DSM... and other collaborators

Completed

Is Iron Deficiency the Cause of Anemia Among Women in Cambodia?

Inflammation | Anemia | Iron Deficiency | Infection | Hemoglobin Disorder

Cambodia
International AIDS Vaccine Initiative
National Institute of Allergy and Infectious Diseases (NIAID); Access to Advanced...

Not yet recruiting

A Clinical Trial to Evaluate the Safety and Immunogenicity of a Prophylactic HIV Vaccine Candidate

Hiv
International AIDS Vaccine Initiative
Brigham and Women's Hospital; George Washington University; Redemption Hospital; East-West Medical Research Institute

Active, not recruiting

A Clinical Trial to Evaluate the Safety and Immunogenicity of rVSV∆G-LASV-GPC Vaccine in Adults in Good General Heath

Lassa Fever | Lassa Virus Infection

United States, Liberia
EuroVacc Foundation
Medical Research Council; Centre Hospitalier Universitaire Vaudois; MRC/UVRI... and other collaborators

Completed

Safety and Immunogenicity Study of a DNA Vaccine Combined With Protein Vaccine Against HIV/AIDS (EV06)

HIV/AIDS

Uganda
Lata Medical Research Foundation, Nagpur
International Clinical Epidemiology Network (INCLEN) TRUST; Indira Gandhi Medical... and other collaborators

Completed

IndiaCLEN Multicentre Trial of Home Versus Hospital Oral Amoxicillin for Management of Severe Pneumonia in Children (ISPOT)

Pneumonia

India
University of Oxford
University of Washington; KEMRI-Wellcome Trust Collaborative Research Program; International AIDS Vaccine Initiative and other collaborators

Completed

Targeted Screening of At-Risk Adults for Acute HIV-1 Infection (AHI)

HIV

Kenya
Rockefeller University
Bill and Melinda Gates Foundation; International AIDS Vaccine Initiative; Aaron... and other collaborators

Completed

Study of a Potential Preventive Vaccine Against HIV in Healthy Volunteers (ADVAX-EP)

HIV Infections

United States
U.S. Army Medical Research and Development Command
GlaxoSmithKline; United States Agency for International Development (USAID); The...

Completed

A Study to Determine Whether 2 Investigational Malaria Vaccines Are Safe, Protective Against Malaria in Adults

Malaria

United States
Helen Keller International
London School of Hygiene and Tropical Medicine; University College, London; United... and other collaborators

Completed

SMS Messages to Increase Child Egg Consumption, a C-rct in Nepal

Dietary Habits

Nepal
Harvard School of Public Health (HSPH)
Ethiopian Public Health Institute; CIMMYT International Maize and Wheat Improvement... and other collaborators

Completed

Translating Adoption of Improved Varieties Into Nutritional Impact (QPM)

Malnutrition

Clinical Trials Sponsored by International Trachoma Initiative

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mali

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations