Clinical Trials Sponsored by Leiden Academic Center for Drug Research, the Netherlands

Total 80 results

Centre for Human Drug Research, Netherlands
Leiden University Medical Center; Leiden Academic Center for Drug Research,...

Completed

Adalimumab Microneedles in Healthy Volunteers

Pain | Injection Site

Netherlands
Centre for Human Drug Research, Netherlands
Leiden University Medical Center; Micreos

Enrolling by invitation

Skin Barrier and Microbiome of CTCL Patients

Lymphoma, T-Cell, Cutaneous

Netherlands
Leiden University Medical Center
GlaxoSmithKline; Academisch Ziekenhuis Groningen; Netherlands Organisation for... and other collaborators

Terminated

Modification Of Disease Outcome In COPD

Chronic Obstructive Pulmonary Disease

Netherlands
The European Uro-Oncology Group
Centre for Human Drug Research, Netherlands

Completed

PET/CT and WB MRI for Staging and Response in CRPC Patients Receiving Enzalutamide

Prostate Cancer Metastatic

Netherlands
Surgimab
Erasmus Medical Center; Catharina Ziekenhuis Eindhoven; Leiden University Medical... and other collaborators

Completed

Phase I of SGM-101 in Patients With Cancer of the Colon, Rectum or Pancreas

Metastatic Colorectal Cancer | Colon Cancer | Pancreas Cancer | Recurrent Colorectal Carcinoma | Rectum Cancer

Netherlands
The European Uro-Oncology Group
Centre for Human Drug Research, Netherlands

Recruiting

Feasibility of Neo-adjuvant Versus Adjuvant Chemotherapy in Upper Tract Urothelial Carcinoma (URANUS)

Upper Tract Urothelial Carcinoma

Norway, Spain, Netherlands
The European Uro-Oncology Group
Centre for Human Drug Research, Netherlands

Completed

Imaging Staging and Response Prediction in Metastatic Hormono-Sensitive Prostate Cancer Patients Receiving Enzalutamide

Prostate Cancer Metastatic

Netherlands
Sinno H.P. Simons
Radboud University Medical Center; ZonMw: The Netherlands Organisation for... and other collaborators

Completed

Population PK/PD of Off Label Drugs in Premature Neonates (DINO)

Premature Birth

Netherlands
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Leids...

Completed

Pan-European Study on Geriatric Rehabilitation After COVID-19 Disease (EU-COGER)

COVID-19

Ireland, United Kingdom, Germany, Netherlands, Spain, Czechia, Israel, Italy, Malta, Russian Federation
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Terminated

TIME ASPIRIN: Chronotherapy With Aspirin for Reduction of Cardiovascular Disease (TImE ASPIRIN)

Cardiovascular Diseases

Netherlands
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Unknown

Stem Cell Therapy to Improve the Muscle Function of Patients With Partly Denervated Muscles of the Arm

Brachial Plexus Injury

Netherlands
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Unknown

The Efficacy of a Cognitive-Behavioural Intervention in Deliberate Self-Harm Patients

Self-Injurious Behavior

Netherlands
Lioe-Fee de Geus-Oei, MD PhD
Amsterdam UMC, location VUmc; The Netherlands Cancer Institute; Centre for Human...

Terminated

[18F]Fluoro-PEG-folate PET/CT Imaging in Epithelial Ovarian Cancer

Epithelial Ovarian Cancer

Netherlands
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Repeated GON Injections in CCH (REGON)

Cluster Headache

Netherlands
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Enrolling by invitation

"Adding DNA-test for Screening of HLA-DQ2 and DQ8 to Improve Early Diagnosis of Celiac Disease" (GLUTEN-GEN)

Celiac Disease in Children

Netherlands
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Active, not recruiting

REduction of LEvothyroxine in Adults; a SElf Controlled Study (RELEASE)

Hypothyroidism

Netherlands
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

A Mouth Education Program for Dry Mouth (MEP)

Frailty | Xerostomia | End of Life | Dry Mouth

Netherlands
Academisch Ziekenhuis Maastricht
The Netherlands Cancer Institute; ZonMw: The Netherlands Organisation for Health...

Completed

Pharmacokinetic Boosting of Osimertinib (OSIBOOST)

Non Small Cell Lung Cancer

Netherlands
PsyQ
Leiden University Medical Center; ZonMw: The Netherlands Organisation for Health...

Completed

Attentional Bias Modification in Patients With Posttraumatic Stress Disorder

Posttraumatic Stress Disorder

Netherlands
Leiden University Medical Center
Erasmus Medical Center; ZonMw: The Netherlands Organisation for Health Research... and other collaborators

Recruiting

Oral Contraceptive Pill Compared With Vitamin E in Women With Migraine (WHATT)

Migraine | Migraine;Menstrual

Netherlands
Leiden University
Radboud University Medical Center; ZonMw: The Netherlands Organisation for... and other collaborators

Completed

Improving PTSD Treatments for Adults With Childhood Trauma (IMPACT)

Post Traumatic Stress Disorder

Netherlands
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Dutch...

Completed

Synergetic B-cell Immodulation in SLE (SYNBIoSe)

Lupus Erythematosus, Systemic

Netherlands
Erasmus Medical Center
Leiden University Medical Center; ZonMw: The Netherlands Organisation for Health... and other collaborators

Terminated

Early Convalescent Plasma Therapy for High-risk Patients With COVID-19 in Primary Care (the CoV-Early Study) (CoV-Early)

Covid19

Netherlands
UMC Utrecht
Leiden University Medical Center; The Interuniversity Cardiology Institute... and other collaborators

Terminated

The Dutch Asymptomatic Mitral Regurgitation Trial (Dutch AMR)

Mitral Valve Insufficiency | Diseases of Mitral Valve | Heart; Disease, Mitral(Valve)

Netherlands
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Horizon...

Recruiting

Phase I/II Clinical Trial Stem Cell Gene Therapy in RAG1-Deficient SCID (RAG1-SCID)

Severe Combined Immunodeficiency Due to RAG1 Deficiency

Spain, Netherlands, Italy, Poland, Australia, Turkey, United Kingdom
Maxima Medical Center
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Leiden University... and other collaborators

Not yet recruiting

Optimal Postoperative Chest Tube and Pain Management in Patients Surgically Treated for Primary Spontaneous Pneumothorax (Pneumotrial)

Pain, Postoperative | VATS | Locoregional Anaesthesia | Thoracic Epidural | Pneumothorax, Primary Spontaneous | Chest Tube Drainage
Leiden University Medical Center
Erasmus Medical Center; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Active, not recruiting

Aeration, Breathing, Clamping Study 3 (ABC3)

Preterm Infant | Birth, Preterm

Netherlands
Suzanne C. Cannegieter, MD PhD
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Pot-Cast: Thrombosis Prophylaxis During Plaster Cast Lower Leg Immobilisation (Pot-Cast)

Pulmonary Embolism | Deep Venous Thrombosis

Netherlands
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; VieCuri... and other collaborators

Active, not recruiting

Rule Out of ACS in Primary Care Using a Decision Rule for Chest Pain Including Hs-troponin I POCT (POB HELP)

Myocardial Infarction | Chest Pain | Acute Coronary Syndrome

Netherlands
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; University...

Unknown

The (Cost-) Effectiveness of Mindfulness-training and Cognitive Behavioural Therapy in Adolescents and Young Adults With Deliberate Self Harm (DSH)

Self-Injurious Behavior

Netherlands
Radboud University Medical Center
Leiden University Medical Center; ZonMw: The Netherlands Organisation for Health... and other collaborators

Not yet recruiting

LSD to Improve Cluster Headache Impact Trial (LICIT)

Chronic Cluster Headache
Suzanne C. Cannegieter, MD PhD
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Pot-Kast: Thrombosis Prophylaxis After Knee Arthroscopy (Pot-Kast)

Pulmonary Embolism | Deep Venous Thrombosis

Netherlands
Bispebjerg Hospital
University of Copenhagen; Duke University; The Ministry of Science, Technology... and other collaborators

Completed

Impact of CES1 Genotype on Metabolism of Methylphenidate

Carboxylesterase 1 (CES1) Genotype | CES1 Activity

Denmark
Leiden University Medical Center
Maastricht University Medical Center; FrieslandCampina; ZonMw: The Netherlands... and other collaborators

Recruiting

The VOILA Intervention Study (VOILA)

Aging

Netherlands
Bispebjerg Hospital
University of Copenhagen; Duke University; The Ministry of Science, Technology... and other collaborators

Completed

Metabolism of Methylphenidate and Enalapril Based on CES1 Genotype

Carboxylesterase 1 (CES1) Genotype | CES1 Activity

Denmark
Leiden University Medical Center
Erasmus Medical Center; Catharina Ziekenhuis Eindhoven; Amsterdam UMC, location... and other collaborators

Recruiting

SGM-101 in Locally Advanced and Recurrent Rectal Cancer (SGM-LARRC)

Rectal Cancer | Recurrent Rectal Cancer

Netherlands
Radboud University Medical Center
Universitaire Ziekenhuizen KU Leuven; ZonMw: The Netherlands Organisation for...

Not yet recruiting

Perioperative SDD to Prevent Infectious Complications After Esophagectomy (PERSuaDER)

Esophageal Cancer
Erasmus Medical Center
University Medical Center Groningen; Academisch Medisch Centrum - Universiteit... and other collaborators

Active, not recruiting

SWITCH ON: Analysing the Immunogenicity of Additional Booster Vaccinations in HCW (SWITCHON)

Covid-19 Vaccination

Netherlands
University Medical Center Groningen
Leiden University Medical Center; ZonMw: The Netherlands Organisation for Health... and other collaborators

Recruiting

Self-management Compared to Care-as-usual for Men With Lower Urinary Tract Symptoms

Lower Urinary Tract Symptoms

Netherlands
Leiden University Medical Center
University Medical Center Groningen; UMC Utrecht; Academisch Medisch Centrum... and other collaborators

Recruiting

Genetic Risk Factors for Multi-system Inflammatory Syndrome in Children and Pediatric Post COVID Condition (GRIP)

COVID-19 | Post-Acute COVID19 Syndrome | Post-COVID-19 Syndrome | Post-Acute COVID-19 | Post COVID-19 Condition | Multi-System Inflammatory Syndrome in Children | Pediatric Inflammatory Multisystem Syndrome

Netherlands
Parnassia Addiction Research Centre
Radboud University Medical Center; Columbia University; Academisch Medisch Centrum... and other collaborators

Not yet recruiting

Efficacy and Safety of Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder

Cocaine Use Disorder
Academisch Medisch Centrum - Universiteit van Amsterdam...
KU Leuven; ZonMw: The Netherlands Organisation for Health Research and Development and other collaborators

Recruiting

(Cost)-Effectiveness of ABFT for Suicidal Youth. (REPAIR)

Suicidal Ideation

Netherlands
ZonMw: The Netherlands Organisation for Health...
Cardiff University; University Medical Center Groningen; Erasmus Medical Center; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) and other collaborators

Unknown

Implementation of Guidelines on Hereditary or Familial Colorectal Cancer (RISCO)

Colorectal Neoplasms, Hereditary Nonpolyposis
Leiden University Medical Center
Maastricht University Medical Center; ZonMw: The Netherlands Organisation for... and other collaborators

Recruiting

The Effecttiveness of Intratympanic Methylprednisolon Injections Compared to Placebo in the Treatment of Vertigo Attacks in Meniere's Disease (PREDMEN)

Meniere Disease

Netherlands
Leiden University Medical Center
Medtronic; ZonMw: The Netherlands Organisation for Health Research and Development and other collaborators

Completed

Holmium Radioembolization as Adjuvant Treatment to RFA for Early Stage HCC: Dose Finding Study (HORA EST HCC)

HCC | Early Stage HCC

Netherlands
Erasmus Medical Center
Universitaire Ziekenhuizen KU Leuven; Academisch Medisch Centrum - Universiteit... and other collaborators

Recruiting

Doxapram Therapy in Preterm Infants (DOXA Trial)

Respiratory Insufficiency | Apnea of Prematurity

Belgium, Netherlands, Canada
Rijnstate Hospital
University Medical Center Groningen; Maastricht University Medical Center; Leiden... and other collaborators

Recruiting

Effects of Preoperative Multidisciplinary Team Meetings for High-risk, Adult, Noncardiac Surgical Patients (PREPARATION)

Postoperative Complications | Interdisciplinary Communication | Surgical Procedures, Operative | Preoperative Care | Cost-Benefit Analysis | Noncardiac Surgery | Comorbidities and Coexisting Conditions | Patient Care Team

Netherlands
Erasmus Medical Center
Universitaire Ziekenhuizen KU Leuven; ZonMw: The Netherlands Organisation for... and other collaborators

Terminated

Effect of Lamotrigine on Cognition in NF1 (NF1-EXCEL)

Neurofibromatosis Type 1

Spain, Belgium, Netherlands
Maxima Medical Center
Radboud University Medical Center; Academisch Medisch Centrum - Universiteit... and other collaborators

Completed

Optimal Postoperative Pain Management After Lung Surgery (OPtriAL)

Pain, Postoperative | Lung Cancer | VATS | Locoregional Anaesthesia | Thoracic Epidural

Netherlands
University Medical Center Groningen
Radboud University Medical Center; Erasmus Medical Center; Academisch Medisch... and other collaborators

Recruiting

Reduced Anticoagulation Targets in ECLS (RATE) (RATE)

Heart Failure | Thrombosis | Respiratory Failure | Bleeding | Extracorporeal Membrane Oxygenation

Netherlands

Clinical Trials Sponsored by Leiden Academic Center for Drug Research, the Netherlands

Sponsors and Collaborators

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