Clinical Trials Sponsored by Merck Serono Co., Ltd.

Total 215 results

Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd.

Terminated

Efficacy and Safety of Crinone Versus Combination Medication (ACCESS)

Infertility

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Terminated

Efficacy Study of Oral Nicorandil on Improving Microvascular Function in Female Non-obstructive Coronary Artery Disease (CAD) Participants (SPET)

Non-obstructive Coronary Artery Disease

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Terminated

Efficacy of Oral Bisoprolol on Heart Rate Reduction in Chinese Chronic Heart Failure Participants (Biso-CHF)

Heart Failure

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

A Randomized Controlled Study to Assess the Effects of Bisoprolol and Atenolol on Resting Heart Rate and Sympathetic Nervous System's Activity in Subjects With Essential Hypertension

Hypertension

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Terminated

Colposeptine for the Treatment of Bacterial Vaginosis

Vaginosis, Bacterial

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

A Study to Explore Correlation Between Symptoms and Signs of Polycystic Ovarian Syndrome (PCOS) and Risk of Over-response to Ovarian Stimulation (ARTIST)

Polycystic Ovary Syndrome

Germany
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ Electromechanical Device for Growth Hormone Treatment (ECOS CHN)

Growth Disorders

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., Japan

Terminated

A Multicentre, Open Label, Phase 1 Trial in Japan of the Mitogen Activated Protein Extracellular Signal Regulated Kinase (MEK) Inhibitor Pimasertib Given Orally to Subjects With Solid Tumors as Monotherapy

Hepatocellular Carcinoma | Advanced Solid Tumors

Japan
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

Comparison of Bisoprolol With Metoprolol Succinate Sustained-release on Heart Rate and Blood Pressure in Hypertensive Patients (CREATIVE)

Hypertension

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

Predictive Markers in Chinese Growth Hormone Deficiency (GHD) Children Treated With Saizen®

Dwarfism, Pituitary
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

Retrospective Study to Estimate the Current Status of Patients With Non-Obstructive coroNary Artery Disease (RESPOND)

Non-Obstructive Coronary Artery Disease

Germany
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

Research on Nicorandil Treatment of Patients Diagnosed as CHD (Coronary Heart Disease) With Stable Angina (SIGMART)

Coronary Disease | Stable Angina

China
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., Japan

Completed

Trial to Assess the Clinical Efficacy and Safety of MSJ-0011 in Inducing Ovulation in Anovulatory or Oligo-ovulatory Japanese Women

Polycystic Ovarian Syndrome | Anovulation | Oligo-ovulation | Hypothalamic-pituitary Dysfunction

Japan
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., Japan

Completed

Study of Tecemotide (L-BLP25) in Participants With Stage III Unresectable Non-small Cell Lung Cancer (NSCLC) Following Primary Chemoradiotherapy

Non-small Cell Lung Cancer

Germany
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., Japan

Completed

SJ-0021 (Gonalef®) Versus Purified Pituitary Gonadotropin (Fertinorm-P®) for Ovulation Induction in Japanese Infertile Women

Infertility | Ovulation Induction

Japan
EMD Serono
Merck KGaA, Darmstadt, Germany; Ono Pharmaceutical Co. Ltd

Terminated

Phase 2 Extension Trial in Patients With Relapsing-Remitting Multiple Sclerosis (RRMS) (DreaMS)

Multiple Sclerosis

United States, Belgium, Canada, Czech Republic, Germany, Japan, Poland, Russian Federation, Spain, Ukraine, Greece
EMD Serono
Merck Pte. Ltd., Singapore

Completed

A Multicenter Phase 3 Study of Interferon-beta-1a for the Treatment of Chronic Hepatitis C in Asian Subjects

Hepatitis C
Merck KGaA, Darmstadt, Germany
Merck Serono Australia Pty Ltd

Completed

Post Marketing Surveillance Study to Evaluate the Tolerability of Rebif® New Formulation in Patients With Relapsing Multiple Sclerosis in an Australian Clinical Setting. (ReNew)

Multiple Sclerosis

Australia
Merck KGaA, Darmstadt, Germany
Merck Serono Australia Pty Ltd

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Australia (ECOS AUS)

Growth Disorders

Australia
Sewon Cellontech Co., Ltd.

Unknown

the Safety and Efficacy of Collagen Injection in Patients With Plantar Fasciitis

Plantar Fasciitis

Korea, Republic of
Sewon Cellontech Co., Ltd.

Unknown

The Post-marketing Surveillance to Evaluate the Efficacy of CHONDRON (Autologous Cultured Chondrocyte) by Arthroscopy

Osteoarthritis | Traumatic Arthritis

Korea, Republic of
Sewon Cellontech Co., Ltd.

Unknown

Efficacy and Safety of Chondron (Autologus Chondrocyte) in Patients With Cartilage Defects in Their Ankle

Defect of Articular Cartilage | Degenerative Joint Disease of Ankle and/or Foot | Ankle (Ligaments); Instability, Familial

Korea, Republic of
Sewon Cellontech Co., Ltd.

Unknown

the Efficacy and Safety of a Modified Microfracture Using Collagen Compared to Those of a Simple Microfracture in Ankle

Defect of Articular Cartilage

Korea, Republic of
Sewon Cellontech Co., Ltd.

Completed

Effects of CHONDRON (Autologous Chondrocytes) With Ankle Cartilage Defect

Articular Cartilage Defects of Ankle Joint

Korea, Republic of
Sewon Cellontech Co., Ltd.

Unknown

Comparison of Efficacy and Safety of Microfracture and Modified Microfracture

Osteoarthritis | Defect of Articular Cartilage | Traumatic Arthritis

Korea, Republic of
Sewon Cellontech Co., Ltd.

Unknown

Efficacy of Intra-articular Collagen Injection in Patients With Knee Joint Pain Compared to Normal Saline Injection

Osteoarthritis | Traumatic Arthritis | Chondromalacia

Korea, Republic of
Sewon Cellontech Co., Ltd.

Unknown

the Safety and Efficacy Evaluation of Chondron Compared With Mircrofracture of Knee

Defect of Articular Cartilage | Articular Cartilage Disorder of Knee | Degeneration; Articular Cartilage, Knee

Korea, Republic of
Sewon Cellontech Co., Ltd.

Unknown

Efficacy and Safety of SurgiFill™ on Spinal Fusion

Spinal Fusion Acquired | Fusion of Spine (Disease)

Korea, Republic of
Sewon Cellontech Co., Ltd.

Completed

Observation of the Result After Chondron (Autologous Chondrocytes) Treatment

Articular Cartilage Defects of Knee

Korea, Republic of
Sewon Cellontech Co., Ltd.

Unknown

The Post-marketing Surveillance to Evaluate the Efficacy and Safety of a CHONDRON (Autologous Cultured Chondrocyte)

Osteoarthritis | Traumatic Arthritis

Korea, Republic of
Sewon Cellontech Co., Ltd.

Completed

An Efficacy and Safety Study of TheraFill® Versus KOKEN for 3 Months on Nasolabial Folds

Nasolabial Folds

Korea, Republic of
TiumBio Co., Ltd.
Merck Sharp & Dohme LLC

Recruiting

Study of TU2218 in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Solid Tumor

United States
Qurient Co., Ltd.
Merck Sharp & Dohme LLC

Recruiting

Oral Axl/Mer/CSF1R Selective Tyrosine Kinase Inhibitor Q702 in Combination With Pembrolizumab in Patients With Selected Advanced Solid Tumors

Cervical Cancer | Gastric Cancer | Esophageal Cancer | Hepatocellular Cancer

Korea, Republic of, United States
InventisBio Co., Ltd
Merck Sharp & Dohme LLC

Active, not recruiting

Study to Evaluate D-1553 in Subjects With Solid Tumors

NSCLC | Solid Tumor, Adult | CRC

United States, Taiwan, Australia, Korea, Republic of
Qurient Co., Ltd.
Merck Sharp & Dohme LLC

Recruiting

Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors

Metastatic Cancer | Advanced Cancer

United States, Korea, Republic of
Merck KGaA, Darmstadt, Germany
Merck Serono GmbH, Germany; Merck B.V., Netherlands; Merck A.E., Greece; Merck... and other collaborators

Completed

PERgoveriS In Stratified Treatment for Assisted Reproductive Technique (PERSIST)

Assisted Reproductive Techniques | Reproductive Technology, Assisted

Italy, Russian Federation, United Kingdom, Germany, Poland, Finland, Slovakia, Netherlands, Denmark, France, Greece
Organon and Co
Merck Frosst Canada Ltd.

Terminated

Ezetimibe Plus Simvastatin Versus Simvastatin in Patients With Hypercholesterolemia and Coronary Risk Factors (P03405)

Atherosclerosis | Hypercholesterolemia
Bayer
Novartis Pharmaceuticals; Biogen; EPID Research; Merck Serono Europe Ltd

Completed

EPID Multiple Sclerosis Pregnancy Study

Multiple Sclerosis

Finland
Jacobio Pharmaceuticals Co., Ltd.
Merck Sharp & Dohme LLC

Recruiting

JAB-BX102 Monotherapy and Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors

Solid Tumor

China
Peking University Third Hospital
Merck Serono GmbH, Germany; Fountain Medical Development Co., Ltd.; Guangzhou...

Unknown

To Investigate the Cumulative Live Birth Rates Using GnRH Antagonist or Agonist Protocol for COS in ART Treatment (CLBR)

Sterility

China
Seagen Inc.
Merck Sharp & Dohme LLC; RemeGen Co., Ltd.

Recruiting

Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2

Urothelial Carcinoma

United States, Canada, Australia, Singapore
Eisai Co., Ltd.
Merck Sharp & Dohme LLC

Completed

A Trial of Lenvatinib Plus Pembrolizumab in Participants With Hepatocellular Carcinoma

Hepatocellular Carcinoma

United States, Spain, France, Italy, Japan, Russian Federation, United Kingdom
Eisai Co., Ltd.
Merck Sharp & Dohme LLC

Completed

Phase 1b Trial of Lenvatinib Plus Pembrolizumab in Participants With Selected Solid Tumors

Solid Tumors

Japan
Adlai Nortye Biopharma Co., Ltd.
Merck Sharp & Dohme LLC

Active, not recruiting

AN0025 and Pembrolizumab Combination in Advanced Solid Tumors

Cervical Cancer | Triple-negative Breast Cancer | NSCLC, Squamous or Non-Squamous | Urothelial Carcinoma of the Bladder | Microsatellite Stable (MSS) Colorectal Cancer (CRC)

United States, France
Korea University Guro Hospital
Sewoon Medical Co., Ltd

Unknown

Efficacy and Safety of Electric Stimulation-guided Epidural Anesthesia for Cesarean Section

Epidural Anesthesia

Korea, Republic of
Keio University
Merck Sharp & Dohme LLC; Ohara Pharmaceutical Co., Ltd.

Recruiting

Imatinib Mesylate in Combination With Pembrolizumab in Patients With Melanoma

Melanoma

Japan
Shenzhen Ionova Life Sciences Co., Ltd.
Merck Sharp & Dohme LLC

Recruiting

An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors

Cancer | Solid Tumor, Adult | Solid Carcinoma | Solid Tumor, Unspecified, Adult | Cancer Metastatic | Tumor, Solid

United States
Jichi Medical University
Merck Sharp & Dohme LLC; Satt Co.,Ltd

Completed

To Compare the Effectiveness of Suvorexant vs Placebo on Sleep Pressure in Hypertensives With Insomnia (Super1)

Hypertension | Insomnia

Japan
Benhealth Biopharmaceutical (Shenzhen) Co., Ltd.
Shenzhen Second People's Hospital

Unknown

Targeted T-cell Therapy in Solid Tumors

Malignant Solid Tumor

China
Zai Lab (Hong Kong), Ltd.
Merck Sharp & Dohme LLC; Zai Biopharmaceutical (Shanghai) Co., Ltd.

Recruiting

A Phase 1 Study of ZL-1218 in Subjects With Advanced Solid Tumors

Malignant Solid Tumor

United States, Spain

Clinical Trials Sponsored by Merck Serono Co., Ltd.

Sponsors and Collaborators

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