Clinical Trials Sponsored by Optos, PLC.

Total 11327 results

Padagis LLC
Impax Laboratories, LLC

Completed

Comparative Safety and Efficacy of Two Treatments in the Treatment of Vulvar and Vaginal Atrophy

Atrophy

United States
Saptalis Pharmaceuticals LLC
bioRASI, LLC

Completed

A Bioequivalence Study With Clinical Endpoints to Evaluate the Safety and Therapeutic Equivalence of Permethrin Cream 5% & Elimite™ in Subjects With Scabies

Scabies

United States
Nearmedic Plus LLC
OCT LLC

Terminated

Phase 2a Study of PBTZ169

Tuberculosis
Pure Purr LLC
Pharmaxi LLC

Completed

Study of the Effect of the VR Technology on Recovery of the Autonomic Nervous System in Volunteers Affected by Stress

Stress

Ukraine
Monsanto Company, LLC
Solae, LLC

Completed

Efficacy Study of Stearidonic Acid (SDA) Soybean Oil-containing Foods on Red Blood Cell Fatty Acid Content

Healthy Volunteers | Markers of Cardiovascular Risk

United States
Cassava Sciences, Inc.
Premier Research Group plc

Active, not recruiting

Simufilam 50 mg or 100 mg for Mild-to-Moderate Alzheimer's Disease (REFOCUS-ALZ)

Alzheimer Disease

United States, Korea, Republic of, Canada, Puerto Rico
Tonix Pharmaceuticals, Inc.
Premier Research Group plc

Active, not recruiting

Assessment of Delayed-type Hypersensitivity Reactions to SARS-CoV-2 Peptide Antigens (COVID-19 DTH)

Detection of Delayed-type Hypersensitivity Reactions to SARS-CoV-2 in Individuals Exposed to SARS-CoV-2

United States
Innocoll
Duke University; Premier Research Group plc

Completed

Safety and Efficacy of an Antibiotic Implant in Cardiac Surgical Subjects at Higher Risk for Sternal Wound Infection

Cardiac Surgery | Sternal Wound Infection

United States
Innocoll
Duke University; Premier Research Group plc

Completed

A Study of an Antibiotic Implant in General Surgical Subjects at Higher Risk for Surgical Wound Infection

Surgical Wound Infection | Colorectal Surgery

United States
Naurex, Inc, an affiliate of Allergan plc

Terminated

Study of Monotherapy Rapastinel in the Prevention of Relapse in Patients With Major Depressive Disorder (MDD)

Depressive Disorder, Major

United States, Poland, Hungary, Japan, Slovakia
Naurex, Inc, an affiliate of Allergan plc

Terminated

Study of Rapastinel as Monotherapy in Patients With MDD

Depressive Disorder, Major

United States
Naurex, Inc, an affiliate of Allergan plc

Terminated

A Study of Rapastinel for Rapid Treatment of Depression and Suicidality in Major Depressive Disorder

Depressive Disorder, Major

United States
Naurex, Inc, an affiliate of Allergan plc

Completed

A Study of Rapastinel as Adjunctive Therapy in the Prevention of Relapse in Patients With Major Depressive Disorder

Depressive Disorder, Major

United States
Naurex, Inc, an affiliate of Allergan plc

Completed

A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-01)

Depressive Disorder, Major

United States
West-Ward Pharmaceutical
Premier Research Group plc

Completed

Study of Oral Morphine Sulfate Administration in Pediatric Subjects

Pain, Postoperative

United States
Naurex, Inc, an affiliate of Allergan plc

Completed

Assessment of Effect of Rapastinel on Driving Performance

Driving Performance

United States, Canada
Paion UK Ltd.
Premier Research Group plc

Completed

Multiple Dose Safety and Efficacy Study Evaluating CNS 7056 Versus Midazolam in Patients Undergoing Colonoscopy

Sedation

United States
Wex Pharmaceuticals Inc.
Premier Research Group plc

Terminated

The Purpose of This Study is to Determine if Tetrodotoxin (TTX) is Effective in the Treatment of Pain Resulting From Chemotherapy Treatment (TTX-CINP-201)

Pain | Neuropathic Pain | Peripheral Neuropathy

United States
FrieslandCampina WAMCO Nigeria PLC
Lagos State University

Unknown

The Effect of Fortified Growing-up Milk on Growth and Micronutrient Status of Nigerian Toddlers (GaGA)

Enterobacteriaceae Infections | Nutritional Deficiency | Iron-deficiency Anemia | Nutritional Stunting | Nutritional Wasting | Malnutrition; Mild
Naurex, Inc, an affiliate of Allergan plc

Completed

Study of Intravenous NRX-1074 in Patients With Major Depressive Disorder

Major Depressive Disorder

United States
Naurex, Inc, an affiliate of Allergan plc

Completed

Study of Safety, Tolerability and Pharmacokinetics of NRX-1074 in Normal Healthy Volunteers (NRX-1074)

Major Depressive Disorder

United States
CellMed AG, a subsidiary of BTG plc.

Completed

First in Man Clinical Study to Investigate Safety, Tolerability and Pharmacokinetics of Single Ascending Doses of CM3.1-AC100

Healthy

Germany
Intensity Therapeutics, Inc.
Premier Research Group plc

Not yet recruiting

A Study to Investigate Efficacy & Safety of INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3) (INVINCIBLE-3)

Sarcoma,Soft Tissue
HEM Pharma Inc.
Premier Research Group plc

Not yet recruiting

HEM1036 Phase 2 Study in Low Anterior Resection Syndrome

LARS - Low Anterior Resection Syndrome
Guardant Health, Inc.
Premier Research Group plc

Active, not recruiting

Evaluation of the ctDNA LUNAR Test in an Average Patient Screening Episode (ECLIPSE)

Colorectal Cancer

United States
Cassava Sciences, Inc.
Premier Research Group plc

Active, not recruiting

Simufilam 100 mg for Mild-to-Moderate Alzheimer's Disease (RETHINK-ALZ)

Alzheimer Disease

United States, Australia, Canada
Tris Pharma, Inc.
Premier Research Group plc

Completed

Amphetamine Extended-Release Tablets in the Treatment of Adults With ADHD

ADHD

United States
Vyne Therapeutics Inc.
Premier Research Group plc

Completed

A Study (Study 1) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea

Facial Papulopustular Rosacea

United States
Vyne Therapeutics Inc.
Premier Research Group plc

Completed

A Study (Study 2) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea

Facial Papulopustular Rosacea

United States
Paion UK Ltd.
Premier Research Group plc

Completed

A Phase III Study of the Efficacy and Safety of Remimazolam Compared to Placebo and Midazolam in Colonoscopy Patients

Colonoscopy

United States
Paion UK Ltd.
Premier Research Group plc

Completed

Safety and Efficacy of Remimazolam in ASA III and IV Patients Undergoing Colonoscopy

Colonoscopy

United States
Naurex, Inc, an affiliate of Allergan plc

Terminated

Study of Rapastinel as Monotherapy in Patients With Major Depressive Disorder (MDD)

Depressive Disorder, Major

Slovakia, Poland, Hungary, Japan, Russian Federation
Tonix Pharmaceuticals, Inc.
Premier Research Group plc

Terminated

Safety and Efficacy Study of TNX-102 SL in Patients With Military-related PTSD (HONOR)

PTSD

United States
Tonix Pharmaceuticals, Inc.
Premier Research Group plc

Terminated

12-Week Open-Label Extension Study of TNX-102 SL in PTSD Patients

PTSD

United States
Rex Bionics Plc
Generic Devices Consulting, Inc.

Completed

Safety and Feasibility Evaluation of Robot Assisted Physiotherapy Exercises With REX (RAPPER II)

Spinal Cord Injury

Australia, United Kingdom, New Zealand
Naurex, Inc, an affiliate of Allergan plc

Completed

Assessment of Abuse Potential of Rapastinel in Humans

Human Abuse Potential

United States
Paion UK Ltd.
Premier Research Group plc

Completed

Dose-Finding Safety Study Evaluating Remimazolam (CNS 7056) in Patients Undergoing Diagnostic Upper GI Endoscopy

Endoscopy | Procedural Sedation

United States
Naurex, Inc, an affiliate of Allergan plc

Completed

Safety and Pharmacokinetics of NRX-1074 in Normal Volunteers

Healthy

United States
Genuine Research Center, Egypt
Pharmacare PLC, Palestine

Completed

A Bioequivalence Study of Amlodipine / Valsartan From Amlodipine/Valsartan 10/160 Tablets (Pharmacare, Palestine) and Exforge Tablets (Novartis Pharma, USA)

Healthy

Egypt
CellMed AG, a subsidiary of BTG plc.

Completed

Single-centre, Randomised, Double-blind, Placebo-controlled, Four-way Crossover Clinical Study to Investigate Safety and Tolerability and Pharmacokinetics of Single Doses of CM3.1-AC100 in Patients With Type 2 Diabetes

Type II Diabetes Mellitus

Germany
AIDS Malignancy Consortium
National Cancer Institute (NCI); The Emmes Company, LLC; PTC Therapeutics

Terminated

PTC299 in Treating Patients With HIV-Related Kaposi Sarcoma

Kaposi's Sarcoma

United States
ResApp Health Limited
Strategy Health LLC; Ascada Health PC DBA

Active, not recruiting

A Pilot Study for the Collection Of Vocalized, Individual Digital Cough Sound Recordings to Screen for COVID-19 (COVID-Cough)

Covid19

United States
Inception Fertility, LLC
GeneScreen Counseling, LLC

Active, not recruiting

Oocyte Donor Application Discrepancies

Infertility

United States
Alliance Foundation Trials, LLC.
Pharmacyclics LLC.

Active, not recruiting

Study of Ibrutinib in Combination With Revlimid/Dexamethasone in Relapsed/Refractory Multiple Myeloma

Multiple Myeloma | Refractory Multiple Myeloma | Multiple Myeloma in Relapse

United States
Janssen Research & Development, LLC
Pharmacyclics LLC.

Completed

A Study of PCI-32765 (Ibrutinib) in Combination With Either Bendamustine and Rituximab or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Participants With Previously Treated Indolent Non-Hodgkin Lymphoma (SELENE)

Lymphoma

United States, France, Ukraine, United Kingdom, China, Germany, Spain, Argentina, Belgium, Israel, Russian Federation, Turkey, Japan, Australia, Sweden, Korea, Republic of, Brazil, Puerto Rico, Poland
Pharmtechnology LLC
X7 Clinical Research LLC

Completed

Bioequivalence Study of Two Formulations of Tablets Aceclofenac 100 mg in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
SGX Procura LLC

Completed

Observational, Post Market Study in Treating Chronic Upper Extremity Limb Pain (PROC2020PM)

Pain | Upper Limb

United States
Pharmacyclics LLC.
Janssen Research & Development, LLC

Completed

Ibrutinib in Combination With Corticosteroids vs Placebo in Combination With Corticosteroids in Participants With New Onset Chronic Graft Versus Host Disease (cGVHD) (iNTEGRATE)

Chronic Graft Versus Host Disease

United States, Australia, Austria, Canada, China, Croatia, France, Germany, Hungary, Italy, Japan, Korea, Republic of, Singapore, Spain, Taiwan
Janssen Research & Development, LLC
Pharmacyclics LLC.

Terminated

A Safety and Efficacy Study of Ibrutinib in Pediatric and Young Adult Participants With Relapsed or Refractory Mature B-cell Non-Hodgkin Lymphoma

Lymphoma, Non-Hodgkin

United States, France, Poland, United Kingdom, Germany, Taiwan, Spain, Bulgaria, Romania, Turkey, Ukraine, Canada, Korea, Republic of, Netherlands, Russian Federation, Belgium, Brazil, Hungary, Czechia, Sweden
Pharmacyclics LLC.
Janssen Research & Development, LLC

Completed

Safety and Tolerability Study of PCI-32765 in B Cell Lymphoma and Chronic Lymphocytic Leukemia

Follicular Lymphoma | B Cell Lymphoma | Non-Hodgkin's Lymphoma | Burkitt Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | B-cell Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | Diffuse Well-differentiated Lymphocytic Lymphoma | B-Cell Diffuse Lymphoma

United States

Clinical Trials Sponsored by Optos, PLC.

Sponsors and Collaborators

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CROs in Congo

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