Clinical Trials Sponsored by Quell Therapeutics Limited

Total 131 results

Iterum Therapeutics, International Limited

Completed

Efficacy of Ciprofloxacin for the Treatment of Uncomplicated Urinary Tract Infection (uUTI)

Antibiotic Resistant Infection | UTI - Lower Urinary Tract Infection

United States
Cyto Therapeutics Pty Limited

Unknown

A Study to Evaluate the Safety of Neural Stem Cells in Patients With Parkinson's Disease

Parkinson Disease

Australia
Everstar Medicines (Shanghai) Limited

Completed

A Study of Ralinepag in Healthy Chinese Adult Subjects

Healthy Volunteer | Pharmacokinetic Study

China
Ignis Therapeutics (Suzhou) Limited

Recruiting

A Twelve-week, Double-blind, Placebo-controlled, Randomized, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Solriamfetol in the Treatment of Excessive Daytime Sleepiness (EDS) in Patients With Obstructive Sleep Apnea (OSA)

Excessive Daytime Sleepiness Associated With Obstructive Sleep Apnea

China
Achilles Therapeutics UK Limited

Recruiting

ATL001 in Patients With Metastatic or Recurrent Melanoma

Melanoma

Spain, United Kingdom
Iterum Therapeutics, International Limited

Completed

Oral Sulopenem Versus Amoxicillin/Clavulanate for Uncomplicated Urinary Tract Infection in Adult Women (REASSURE)

Cystitis | Urinary Tract Infections

United States
Zentera Therapeutics HK Limited

Completed

A PHASE 1B STUDY OF ZN-C5 IN CHINESE SUBJECTS

Breast Neoplasms

China
Iterum Therapeutics, International Limited

Withdrawn

Safety, Tolerability, and Pharmacokinetics of Sulopenem in Adolescents

Intraabdominal Infections | Urinary Tract Infections | Pyelonephritis Acute

United States
Iterum Therapeutics, International Limited

Completed

Sulopenem Versus Ertapenem for Complicated Intra-abdominal Infection (cIAI)

Intra Abdominal Infections

United States, Bulgaria, Estonia, Georgia, Hungary, Latvia, Poland
Heptares Therapeutics Limited
Allergan

Completed

A Two Part Study to Assess Safety, PK, PD, and Food Effect of Oral HTL0016878

Healthy

United Kingdom
TenNor Therapeutics (Suzhou) Limited

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of TNP-2198 Capsules in Asymptomatic Participants With Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
AffaMed Therapeutics (US) Inc.

Recruiting

Safety and Efficacy of AM712 in Patients With nAMD

Neovascular Age-related Macular Degeneration

United States
TenNor Therapeutics (Suzhou) Limited

Completed

Efficacy and Safety of Rifasutenizol (TNP 2198) in Participants With H. Pylori Infection

H.Pylori Infection

China
TenNor Therapeutics (Suzhou) Limited

Completed

A Phase 1, Single-center, Double-blind, Placebo-controlled Study of TNP-2092 Capsules, and the Food Effect Study After Single-dose Oral Administration of TNP-2092 Capsules

Hyperammonemia

China
TenNor Therapeutics (Suzhou) Limited

Completed

Efficacy and Safety After Multiple Doses of TNP-2198 Capsules, Rabeprazole Sodium Enteric-coated Tablets and Amoxicillin Capsules in Helicobacter Pylori Infected-positive Participants

Helicobacter Pylori Infection

China
TenNor Therapeutics (Suzhou) Limited

Completed

A Study to Evaluate Preliminary Helicobacter Pylori Eradication After Multiple Doses of TNP-2198 Capsules Combined With Rabeprazole Sodium Enteric-coated Tablets, or Rabeprazole Sodium Enteric-coated Tablets and Amoxicillin Capsules

Helicobacter Pylori Infection

China
TenNor Therapeutics (Suzhou) Limited

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Food Effect of TNP-2198 Capsules After Single Oral Dose in Healthy Participants

Helicobacter Pylori Infection

China
TenNor Therapeutics (Suzhou) Limited

Completed

Human Mass Balance and Biotransformation Study of [14C]TNP-2198

Helicobacter Pylori Infection

China
TenNor Therapeutics (Suzhou) Limited

Completed

Safety, Tolerability, Pharmacokinetic Characteristics and Preliminary Efficacy of TNP-2092 Capsules in Liver Cirrhosis Patients With Hyperammonemia

Hyperammonemia

China
ABM Therapeutics Shanghai Company Limited

Recruiting

A Study of ABM-1310 in Patients With BRAF V600-Mutant Relapsed and Drug Resistant Primary Malignant Brain Tumors

Primary Malignant Brain Tumor

China
ABM Therapeutics Shanghai Company Limited

Recruiting

A Study of ABM-1310 in Patients With BRAF V600-Mutant Advanced Solid Tumors

Advanced Solid Tumor | BRAF V600 Mutation

China
Antengene Therapeutics Limited

Terminated

A Study of Evaluating Dual Inhibitor of PAK4 and NAMPT ATG-019 in Advanced Solid Tumors or Non-Hodgkin's Lymphoma (TEACH)

Solid Tumor, Non-Hodgkin's Lymphoma

China, Taiwan
Gyroscope Therapeutics Limited
Novartis Pharmaceuticals

Active, not recruiting

HORIZON: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005

Dry Age-related Macular Degeneration

United States, Germany, United Kingdom, France, Spain, Australia, Poland
Gyroscope Therapeutics Limited
Novartis Pharmaceuticals

Active, not recruiting

FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMD

Eye Diseases | Macular Degeneration | Retinal Degeneration | Geographic Atrophy | Dry Age-related Macular Degeneration | Retinal Disease | Macular Atrophy

United States, United Kingdom
Gyroscope Therapeutics Limited
Novartis Pharmaceuticals

Active, not recruiting

GTSCOPE - To Evaluate the Natural Progression of Dry Age-related Macular Degeneration (AMD)

Macular Degeneration | Retinal Degeneration | Geographic Atrophy | Dry Age-related Macular Degeneration | Retinal Disease | Macular Atrophy

United States, Spain, United Kingdom, France, Germany, Australia, Netherlands, Poland
Monument Therapeutics Limited
ICON plc

Completed

Safety & PK of Single Doses of MT1980

Neuroinflammatory Response

Netherlands
Heptares Therapeutics Limited
Quotient Clinical

Completed

Relative Bioavailability Study in Healthy Subjects to Evaluate the Pharmacokinetics of HTL0009936 After One Dose of Prototype Formulation

Alzheimer's Disease

United Kingdom
Gyroscope Therapeutics Limited
Novartis Pharmaceuticals

Enrolling by invitation

ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent Study (ORACLE)

Age Related Macular Degeneration (AMD)

United States, Germany, Spain, France, Australia, United Kingdom
Gyroscope Therapeutics Limited
Novartis Pharmaceuticals

Active, not recruiting

EXPLORE: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005 (EXPLORE)

Dry Age-related Macular Degeneration

United States, Germany, United Kingdom, Spain, Poland, Australia, France, Netherlands
Antengene Therapeutics Limited

Terminated

Dual TORC1/TORC2 Inhibitor ATG-008 (CC-223) in HBV Positive Advanced Hepatocellular Carcinoma (HCC) Subjects

Hepatocellular Carcinoma

Korea, Republic of, Taiwan, China
Boston Therapeutics
Sugardown Company Limited

Completed

Multicenter Study to Evaluate the Effect of BTI320 on Glycemic Control in Type 2 Diabetes

Type2 Diabetes Mellitus

United States
Kazia Therapeutics Limited
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile, and Metabolite Identification of [14C]-Paxalisib in Healthy Male Subjects

Healthy

United Kingdom
ATXA Therapeutics Limited
Hammersmith Medicines Research

Recruiting

Safety, Pharmacokinetics (PK) and Relative Bioavailability of NTP42:KVA4 as a Solid Oral Dose

Healthy

United Kingdom
Cynata Therapeutics Limited
Cerebral Palsy Alliance

Completed

The MEseNchymal coviD-19 Trial: MSCs in Adults With Respiratory Failure Due to COVID-19 or Another Underlying Cause (MEND)

Covid19 | Acute Respiratory Distress Syndrome

Australia
Iterum Therapeutics, International Limited
Waterbury Hospital

Withdrawn

Azithromycin Plus Hydroxychloroquine for COVID-19 Infection

Respiratory Tract Infection Viral

United States
Visirna Therapeutics HK Limited
Arrowhead Pharmaceuticals

Not yet recruiting

Study of VSA001 Injection in Chinese Healthy Adult Volunteers

Healthy Adult Volunteers

China
Mateon Therapeutics
Windlas Biotech Private Limited

Completed

A Study to Evaluate the Safety and Efficacy of Artemisinin- a Herbal Supplement on COVID-19 Subjects

Covid19

India
Autifony Therapeutics Limited
King's College London

Completed

Safety, Tolerability and Pharmacokinetics of AUT00206 in Patients With Schizophrenia, and Also Explores the Effects of AUT00206 on Relevant Central Biomarkers.

Schizophrenia

United Kingdom
Autifony Therapeutics Limited
University of Manchester

Completed

A Study to Assess the pharmacoMRI Effects of AUT00206 in Healthy Males

Schizophrenia

United Kingdom
Somnus Therapeutics, Inc.
INC Research Limited

Completed

Study of Sleep-maintenance Activity of 3 Doses of SKP-1041

Sleep Disorder | Primary Insomnia
Fralex Therapeutics
PharmaNet; McDougall Scientific Limited

Terminated

Pain Relief Investigation of Neuromodulation Therapy in an Adult Fibromyalgia Population

Pain | Fibromyalgia

United States, Canada
Cancer Research UK
Heptares Therapeutics Limited

Recruiting

HTL0039732 in Participants With Advanced Solid Tumours

Sarcoma | Neoplasms | Kidney Neoplasms | Uterine Cervical Neoplasms | Stomach Neoplasms | Head and Neck Neoplasms | Lung Neoplasms | Urinary Bladder Neoplasms | Colorectal Neoplasms | Pancreatic Neoplasms | Esophageal Neoplasms | Mesothelioma, Malignant | Prostatic Neoplasms, Castration-Resistant | Pheochromocytomas

United Kingdom
ATXA Therapeutics Limited
Hammersmith Medicines Research

Completed

Safety, Tolerability and Pharmacokinetics of NTP42:KVA4

Healthy

United Kingdom
Karus Therapeutics Limited
University College, London

Withdrawn

A Study of Selective HDAC6 Inhibition With KA2507 in Advanced Biliary Tract Cancer

Biliary Tract Cancer

United Kingdom
Autifony Therapeutics Limited
University of Nottingham

Completed

Evaluating Possible Improvement in Tinnitus Severity After 28 Days Dosing of the Study Drug AUT00063 Compared to Placebo (QUIET-1)

Tinnitus, Subjective

United Kingdom
Helperby Therapeutics Ltd
Richmond Pharmacology Limited

Completed

Effect of Minocycline & Amoxicillin on Antibiotic Resistant Bacteria and Indigenous Microbiotas (ANTIRESDEV)

Antibiotic Resistant Bacteria

United Kingdom
ImmunoBiology Limited
Simbec Research; ORION Clinical Services; Oxford Therapeutics Consulting Limited

Completed

A Phase I Study to Evaluate the Safety and Immunogenicity of PnuBioVax

Pneumococcal Infection

United Kingdom
Hoth Therapeutics, Inc.
Novotech (Australia) Pty Limited

Completed

Safety, Tolerability, Pharmacokinetics and Efficacy of Twice Daily Application of Topical BioLexa in Adult Healthy Subjects and Patients With Mild to Moderate Atopic Dermatitis

Atopic Dermatitis

Australia
AceLink Therapeutics, Inc.
Novotech (Australia) Pty Limited

Completed

To Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AL01211 in Healthy Volunteers

Autosomal Dominant Polycystic Kidney

Australia
DiaMedica Therapeutics Inc
Novotech (Australia) Pty Limited

Completed

An Open Label, Phase 1b, Ascending Dose Study of DM199

Stroke

Australia

Clinical Trials Sponsored by Quell Therapeutics Limited

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