Clinical Trials Sponsored by Roche Pharma AG

Total 593 results

TME Pharma AG

Completed

First-in-human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NOX-H94

Inflammation | Anemia | Chronic Diseases

United Kingdom
Azad Pharma AG

Completed

Bioequivalence Study With Pharmacokinetic Endpoints, Comparing a Single Dose of Iron Sucrose Azad Injection of Azad Pharma Corporation (AG), With a Single Dose of Venofer® Injection of Vifor Corporation (AG) in Healthy Adult Volunteers

Healthy Volunteers

Austria
Tillotts Pharma AG

Completed

TP0501 - Pharmaco-Scintigraphic-Study

Ulcerative Colitis
Tillotts Pharma AG

Completed

TP0502-Pharmaco-Scintigraphic-Study and Amendment

Ulcerative Colitis
TME Pharma AG

Completed

NOX-A12 Multiple Ascending Dose Study in Healthy Volunteers (SNOXA12C101)

Hematopoietic Stem Cell Transplantation

Germany
TME Pharma AG

Completed

NOX-E36 First-in-Human (FIH) Study

Type 2 Diabetes Mellitus | Systemic Lupus Erythematosus | Chronic Inflammatory Diseases
Axxonis Pharma AG

Completed

Continuous Application of Lisuride in Parkinson's Disease by Subcutaneous Infusion

Parkinson's Disease

Germany
Axxonis Pharma AG

Completed

Transdermal Lisuride: a Trial for the Treatment of Patients With Restless Legs Syndrome (RLS)

Restless Legs Syndrome

Germany
S.L.A. Pharma AG

Completed

Evaluation of the Pharmacokinetics of Metronidazole 10% Ointment Applied Peri Anally in Healthy Volunteers and Patients With Perianal Crohn's Disease

Perianal Crohns'

United Kingdom
S.L.A. Pharma AG

Completed

Effect of 2 Doses of EPA on Apoptosis and Cell Proliferation on Colon Mucosa

Adenomatous Polyps

Italy, United Kingdom
The Netherlands Cancer Institute
Roche Pharma AG; Borstkanker Onderzoek Groep

Active, not recruiting

Neoadjuvant Chemotherapy in HER2 Positive Breast Cancer, TRAIN-2 (TRAIN-2)

Breast Cancer | HER2 Positive

Netherlands
Rennes University Hospital
Roche Pharma AG; National Research Agency, France

Completed

BMS_PD-L1_onco : Assessment of the PD-L1 Protein as a Biomarker in Oncology and Hematology (BMS_PD-L1)

Hodgkin Lymphoma | Non-small Cell Lung Cancer | Diffuse Large B-cell Lymphoma | Metastatic Breastcancer

France
University Hospital Inselspital, Berne
Roche Pharma AG; University of Bern

Completed

Tocilizumab for Patients With Giant Cell Arteritis

Giant Cell Arteritis

Switzerland
Jinming Yu
Roche Pharma AG

Unknown

Phase II Study of Erlotinib With Concurrent Radiotherapy in Unresectable NSCLC With Activating Mutation of EGFR in Exon 19 or 21 (RECEL)

Non-small Cell Lung Cancer

China
National Bone Health Alliance
Roche Pharma AG; National Osteoporosis Foundation

Unknown

Changes in Biochemical Markers of Bone Turnover (Serum CTX and PlNP) After Initiation of a "Drug Holiday" From Bisphosphonates

Osteoporosis

United States
Aktion Bronchialkarzinom e.V.
Eli Lilly and Company; Roche Pharma AG

Withdrawn

TS Stratified Chemotherapy and VEGF Inhibition in Non-Squamous Non-Small Cell Lung Cancer - Stage IV (SELECT-A)

Carcinoma, Non-Small-Cell Lung
University of Minnesota
Juvenile Diabetes Research Foundation; Roche Pharma AG

Completed

Delayed Mycophenolate Mofetil in Single-Donor Islet Allotransplantation in Type 1 Diabetes

Hypoglycemia | Type 1 Diabetes

United States
Salvador Gil-Vernet
Roche Pharma AG

Completed

Valganciclovir for Treatment of Cytomegalovirus Infection in Solid Organ Transplant Patients

Cytomegalovirus Infection

Spain
Canadian Cancer Trials Group
AbbVie; Roche Pharma AG; Incyte Corporation

Recruiting

Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma

Lymphoma, B-Cell

Canada
The Netherlands Cancer Institute
Roche Pharma AG; Borstkanker Onderzoek Groep

Active, not recruiting

Triple-B Study;Carboplatin-cyclophosphamide Versus Paclitaxel With or Without Atezolizumab as First-line Treatment in Advanced Triple Negative Breast Cancer (Triple-B)

Breast Cancer

Netherlands
Se-Hoon Lee
Roche Pharma AG; AstraZeneca

Completed

Olaparib and Bevacizumab in Relapsed Small Cell Lung Cancer Subjects (SUKSES-B2)

Lung Cancer

Korea, Republic of
Institut Bergonié
Roche Pharma AG; Ligue contre le cancer, France

Completed

Evaluation of Response to the Neoadjuvant Chemotherapy for Advanced Ovarian Cancer by Multimodal Functional Imaging (IMOVA)

Ovarian Cancer

France
French Innovative Leukemia Organisation
Roche Pharma AG; Janssen-Cilag Ltd.

Completed

Phase II Trial GA101 Inbrutinib B CLL (ICLL07GAI)

Leukemia, Lymphocytic, Chronic, B-Cell

France
Birmingham Women's and Children's NHS Foundation...
Roche Pharma AG

Terminated

A Pilot Trial of Pediatric Liver Transplantation Without Steroids

Evidence of Liver Transplantation

United Kingdom
Tianjin Medical University Cancer Institute and...
Roche Pharma AG

Unknown

Erlotinib in Post Radical Operation NSCLC Patients With EGFR Mutation

Non-small Cell Lung Cancer Stage III

China
University of Chicago
Roche Pharma AG; Breast Cancer Research Foundation

Terminated

Capecitabine as NeoAdjuvant Therapy in Locally Advanced Breast Cancer

Breast Cancer

United States, Nigeria
Yale University
Roche Pharma AG; National Comprehensive Cancer Network; PhytoCeutica

Completed

A Phase I/II, Multi-Center, Open-Label, Dose-Escalation, Safety and Efficacy Study of PHY906 Plus Capecitabine in Patients With Advanced Pancreatic Carcinoma

Pancreatic Cancer

United States
National Center for Tumor Diseases, Heidelberg
Pfizer; Roche Pharma AG

Terminated

Curative Resectability of Not Optimally Resectable Liver and/or Lung Metastases From Colorectal Carcinoma (CRC) Under Intensified Chemotherapy (APRIORI)

Colorectal Carcinoma

Germany
Deok-Hwan Yang
Roche Pharma AG

Unknown

A Prospective Cohort of Obinutuzumab and Chlorambucil (GC) Chemotherapy for the Treatment of Elderly Patients With Chronic Lymphocytic Leukemia Including Next- Generation Sequencing (NGS)-Based Assessment

Chronic Lymphocytic Leukemia

Korea, Republic of
German CLL Study Group
Mundipharma Pte Ltd.; Roche Pharma AG

Completed

FCR or BR in Patients With Previously Untreated B-Cell Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Germany
Lund University Hospital
Mundipharma Pte Ltd.; Roche Pharma AG; Celgene

Completed

Lenalidomide, Bendamustine and Rituximab as First-line Therapy for Patients Over 65 Years With Mantle Cell Lymphoma. (LENA-BERIT)

Mantle Cell Lymphoma

Finland, Denmark, Norway, Sweden
University Hospital, Tours
Roche Pharma AG; French Innovative Leukemia Organisation

Completed

Rituximab Maintenance Versus Observation After First-line Immunochemotherapy by FCR in Older Patients With Chronic Lymphocytic Leukemia (LLC2007SA)

Leukemia

France
German Breast Group
GlaxoSmithKline; Roche Pharma AG; Teva Pharmaceuticals USA

Completed

Addition of Carboplatin to Neoadjuvant Therapy for Triple-negative and HER2-positive Early Breast Cancer (GeparSixto)

Inflammatory Breast Cancer | HER-2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III | Inflammatory Breast Cancer Stage IV

Germany
University of Texas Southwestern Medical Center
Roche Pharma AG; Biogen

Completed

Safety Study of Combination Therapy With Intramuscular Avonex and Oral Cellcept in Patients With Multiple Sclerosis

Multiple Sclerosis

United States
Jean-Luc Van Laethem
Roche Pharma AG

Unknown

Effect on Tumor Perfusion of a Chemotherapy Combining Gemcitabine and Vismodegib Before Surgery in Pancreatic Cancer (NEOPACHI-001)

Pancreatic Adenocarcinoma Resectable

Belgium
The HIV Netherlands Australia Thailand Research...
Roche Pharma AG

Completed

Study of Genetic Polymorphisms in Thai HIV-1 Infected Patients on SQV/r

HIV Infections

Thailand
Association Aquitaine de Recherche Clinique en...
Roche Pharma AG; Chugai Pharma France

Completed

Characterization of the Effect of Tocilizumab in Vivo and in Vitro on T Follicular Helper Cells in Rheumatoid Arthritis Patients and Consequence on B Cells Maturation (Tocihelper)

Arthritis, Rheumatoid | Tocilizumab | T-Lymphocytes, Helper-Inducer

France
University Hospital Freiburg
Roche Pharma AG; Genzyme, a Sanofi Company; Astellas Pharma GmbH

Completed

Phase IV Study to Evaluate Calcineurin Inhibitor Reduced, Steroid Free Immunosuppression After Renal Transplantation (Harmony)

Disorder Related to Renal Transplantation

Germany
Bazell Pharma AG

Not yet recruiting

Pharmacokinetics, Efficacy, Tolerability and Safety of Different Budesonide Oral Gel Doses in Adults' Subjects of Both Genders With Eosinophilic Esophagitis (EoE) (BESIDE)

Eosinophilic Esophagitis
Cinclus Pharma AG
Parexel

Completed

A Study in Patients With Erosive Esophagitis to Investigate Safety, Tolerability, and Healing Rates After 4 Weeks Treatment of X842 or Lansoprazole and Symptom Pattern During Subsequent 4 Weeks Treatment With Lansoprazole

Erosive Esophagitis

Poland, Bulgaria, Serbia, Georgia, United States, Czechia, Hungary, Ukraine
Develco Pharma Schweiz AG

Unknown

Naloxone HCl PR Tablets in Patients With Opioid Induced Constipation (Naxos)

Opioid-Induced Constipation

United Kingdom, Bulgaria, Czechia, Germany, Poland, Portugal, Serbia, Slovakia, Spain
Fundacio Clinic Barcelona
Roche Pharma AG; SOLTI Breast Cancer Research Group

Recruiting

Omission of Surgery in Clinically Low-risk HER2positive Breast Cancer With High HER2 Addiction and a Complete Response Following Standard Anti-HER2-based Neoadjuvant Therapy (ELPIS)

Stage I Breast Cancer | HER2-positive Breast Cancer

Spain
Centre Antoine Lacassagne
Roche Pharma AG; Centre Hospitalier Universitaire de Caen

Recruiting

Stereotaxic Body Irradiation of Oligometastase in Sarcoma (Stereosarc) (Stereosarc)

Sarcoma | Radiosurgery

France
German Breast Group
Sanofi; Roche Pharma AG; Amgen; University Hospital Frankfurt

Completed

Docetaxel, Doxorubicin and Cyclophosphamide Versus Vinorelbine and Capecitabine in Patients Not Sufficiently / Sufficiently Responding as Preoperative Treatment of Locally Advanced or Operable Primary Breast Cancer (GeparTrio)

Breast Cancer
Poitiers University Hospital
Novartis; Roche Pharma AG; Ministry of Health, France

Completed

STI571 ProspectIve RandomIzed Trial: SPIRIT (SPIRIT)

Chronic Myeloid Leukemia

France
University of Alberta
Roche Pharma AG; Institute of Health Economics, Canada

Completed

Using Health-related Quality of Life (HRQL) in Routine Clinical Care

Chronic Obstructive Pulmonary Disease | Pulmonary Fibrosis | Cystic Fibrosis | Pulmonary Hypertension

Canada
Dutch Colorectal Cancer Group
Roche Pharma AG; The Netherlands Cancer Institute

Active, not recruiting

Randomized Phase III Trial of Adjuvant Chemotherapy or Chemoradiotherapy in Resectable Gastric Cancer (CRITICS)

Gastric Cancer

Netherlands
Dr. Yoo-Joung Ko
Roche Pharma AG

Completed

Radiosensitization of AVASTIN® (Bevacizumab) With Stereotactic Body Radiotherapy for Colorectal Liver Metastasis (SBRT-Avastin)

Colorectal Cancer.

Canada
H. Lee Moffitt Cancer Center and Research Institute
Roche Pharma AG

Completed

Study of Capecitabine With Irinotecan and Oxaliplatin (Eloxatin) in Advanced Colorectal Cancer

Colorectal Cancer

United States, Puerto Rico
Grupo Español de Investigación en Cáncer de Ovario
Roche Pharma AG

Terminated

Neoadjuvant Therapy in Advanced Ovarian Cancer With Avastin (NOVA)

Cancer, Ovarian

Spain

Clinical Trials Sponsored by Roche Pharma AG

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bulgaria

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations