Clinical Trials Sponsored by Roche S.p.a

Total 3680 results

Alfasigma S.p.A.

Active, not recruiting

Velusetrag for the Treatment of Chronic Intestinal Pseudo-Obstruction (CIPO).

Chronic Intestinal Pseudo-obstruction

Belgium, Italy, Spain
Probiotical S.p.A.

Completed

Probiotics in Paediatric Asthma Management (ProPAM)

Asthma in Children

Italy
Kedrion S.p.A.

Completed

Clinical Assessment of Pharmacokinetics, Efficacy, and Safety of 10% IVIg in PID Patients (CARES10)

Primary Immunodeficiency Disease

United States
Alfasigma S.p.A.

Terminated

Rifaximin Delayed Release for the Prevention of Recurrent Acute Diverticulitis and Diverticular Complications. (ROAD)

Diverticulitis

France, Germany, Italy, Netherlands, Spain, United Kingdom
Limacorporate S.p.a

Active, not recruiting

MASTER SL Clinical Study

Patients Requiring Hip Replacement

United Kingdom
Alfasigma S.p.A.

Terminated

AvidinOX + [177Lu]DOTA-biotin (or 177Lu-ST2210) Complex in Patients With Liver Metastases From Colorectal Cancer

Liver Metastases

Austria, Italy
Alfasigma S.p.A.

Terminated

Safety, Tolerability, PK, Dosimetry, MTD and Preliminary Efficacy of Intra-lesionally Injected AvidinOX, Followed by IV Escalating Doses of [177Lu]DOTA-biotin in Pts With Injectable Solid Tumors or Lymphomas

Inoperable Solid Tumors or Lymphomas

United States
Philogen S.p.A.

Completed

Combination Therapy of F8IL10 and Methotrexate in Rheumatoid Arthritis Patients

Rheumatoid Arthritis

Italy
Chemi S.p.A.

Completed

Extended-release of Octreotide (LF-PB) for the Treatment of Seroma

Seroma

Italy
Habilita S.p.A.

Unknown

Impact of a New Technology to Functional Recovery Upper Limb in Post Stroke Patients.

Stroke

Italy
CID S.p.A.

Unknown

Safety and Efficacy of the CRE8 Sirolimus-Eluting Stent for the Treatment of De Novo Coronary Artery Lesions

Coronary Artery Disease

China
Chemi S.p.A.

Completed

Extended-release of Octreotide (LF-PB) for the Treatment of Lymphorrhea

Lymphorrhea

Italy
Philogen S.p.A.

Terminated

Combination Therapy of F16IL2 and Doxorubicin in Solid Tumour Patients

Breast Cancer | Advanced Solid Tumor

Italy
RostaQuo S.p.A.

Unknown

Antihypertensive Effect of Rostafuroxin Compared With Losartan in Hypertensive Patients Bearing Specified Gene Mutations

Essential Hypertension

Ireland, Italy, Poland
Alfasigma S.p.A.

Completed

Placebo Controlled Study of 3 Doses of Rifaximin-EIR Tablet to Treat Moderate, Active Crohn's Disease

Crohn's Disease

Israel, Italy, Russian Federation, Poland, Germany, France, Hungary
Limacorporate S.p.a

Not yet recruiting

Physica TT Tibial Plate Follow up Study

Knee Arthropathy

Italy
Philogen S.p.A.

Recruiting

A Study to Evaluate the Safety and Dosimetry of 68Ga-labelled OncoFAP Derivatives in Solid Tumors (FAPrimo)

Breast Cancer | Colorectal Cancer | Pancreas Adenocarcinoma | Oesophageal Cancer

Italy
Philogen S.p.A.

Not yet recruiting

Safety and Preliminary Signs of Efficacy of F8IL10 for Intra-articular Treatment (DekaJoint)

Rheumatoid Arthritis
Guna S.p.a

Recruiting

Performance and Safety Evaluation of MD-Shoulder Collagen Medical Device in the Treatment of Rotator Cuff Syndrome (ROPIRAMED)

Rotator Cuff Injuries | Tendinopathy | Rotator Cuff Tendinitis | Syndrome Rotator Cuff | Tendinoses, Rotator Cuff

Italy
Guna S.p.a

Recruiting

Evaluation of Collagen-based Medical Device Treatment Combined With Physiotherapy in Subjects With Achilles Tendinopathy. (AKITENMED)

Tendinopathy | Achilles Tendinopathy | Insertional Achilles Tendinopathy | Peritendinitis

Italy
Philogen S.p.A.

Recruiting

L19IL2/L19TNF in Skin Cancer Patients (IntriNSiC)

Kaposi Sarcoma | Merkel Cell Carcinoma | BCC - Basal Cell Carcinoma | SCC - Squamous Cell Carcinoma | Keratoacanthoma of Skin | Malignant Adnexal Tumors of the Skin (MATS) | Tumors From Cutaneous T-cell Lymphoma (CTCL)

Spain, France, Italy
XSpline S.p.A.

Recruiting

Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment (CRT-DRIVE)

Left Bundle-Branch Block | Chronic Heart Failure | Cardiac Resynchronization Therapy

United States, Switzerland, Italy, Hungary, Netherlands, Austria, Spain
Limacorporate S.p.a

Recruiting

H-28 DELTA ST-C and Minima Retrospective Study.

Osteoarthritis, Hip

Greece
Limacorporate S.p.a

Not yet recruiting

Multigen Plus H Study

Arthroplasty, Replacement, Knee
Philogen S.p.A.

Recruiting

A Study to Evaluate Safety and Efficacy of L19TNF Plus Lomustine in Patients With Glioblastoma at First Progression (GLIOSTAR)

Glioblastoma

France, Germany, Italy, Switzerland
Philogen S.p.A.

Recruiting

Safety and Early Signs of Efficacy of IL12-L19L19. (DODEKA)

Advanced Solid Tumor | Metastatic Solid Tumor

Italy, Germany, Switzerland
Philogen S.p.A.

Recruiting

Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed Glioblastoma (GLIOSUN)

Glioblastoma

Switzerland
Philogen S.p.A.

Recruiting

Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C Melanoma Patients (NeoDREAM)

Melanoma Stage IIIB/C

Spain, United States, Switzerland
Philogen S.p.A.

Withdrawn

Safety and Efficacy of Different Administration Sequences of L19TNF With Lomustine in Glioblastoma at First Progression (GLIOASTRA)

Glioblastoma
Limacorporate S.p.a

Active, not recruiting

SMR Stemless Shoulder Arthroplasty Clinical Study

Rheumatoid Arthritis | Post-traumatic; Arthrosis | Primary Osteoarthritis | Secondary Osteoarthritis | Rotator Cuff Tear Arthropathy | Avascular Necrosis of the Head of Humerus

Germany, Netherlands, United Kingdom
Limacorporate S.p.a

Completed

Hip Arthroplasty With SL Cementless

Hip Replacement

Czechia
Philogen S.p.A.

Terminated

A Phase I/II Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Rituximab in Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Diffuse Large B-cell Lymphoma (DLBCL)

Germany
Philogen S.p.A.

Terminated

A Study of the Tumor-targeting Human F16IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Very Low-dose Cytarabine in Patients With AML Relapse After Allogeneic Hematopoietic Stem Cell Transplantation

Acute Myeloid Leukemia, Relapsed, Adult

Germany
SOFAR S.p.A.

Completed

Multicentre Observational Study on the Wound Pain Relief Properties of ORTODERMINA®

Wound Healing Disorder

Italy
Kedrion S.p.A.

Completed

Efficacy/Safety of Human Plasminogen Eye Drop in Ligneous Conjunctivitis Patients

Ligneous Conjunctivitis

United States, Italy
SOFAR S.p.A.

Completed

Effect of a Combination of Hyaluronic Acid, Chondroitin Sulphate and Magnesium Trisilicate on Subjects With GastroEsophageal Reflux Disease

Gastro Esophageal Reflux

Belgium
Philogen S.p.A.

Active, not recruiting

A Phase I/II Dose Escalation Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Dacarbazine for Patients With Metastatic Melanoma

Metastatic Melanoma Stage IV

Italy, Germany
Philogen S.p.A.

Completed

L19TNFα in Combination With Doxorubicin in Patients With Advanced Solid Tumours

Advanced Solid Tumors Amenable to Anthracycline Therapy | Sarcoma, Breast Cancer, Lung Carcinomas, and Gynecological Cancer Amenable to Anthracycline Therapy

Germany, Italy
Limacorporate S.p.a

Completed

Prospective Observational Case Series of Primary Hip Arthroplasty With a Short Cemented Stem (Friendly Short)

Total Hip Arthroplasty

Italy
Limacorporate S.p.a

Active, not recruiting

Clinical Study Evaluating the Outcomes of a New Knee System With a Physiological Rollback Mechanism (K-06)

Primary Total Knee Replacement

United Kingdom, Italy
Limacorporate S.p.a

Completed

Physica KR Fluoroscopy Study

Total Knee Replacement

United Kingdom
SOFAR S.p.A.

Completed

Evaluation of GERDOFF Efficacy in Combination With Proton Pump Inhibitor

Gastro-oesophageal Reflux Disease

Italy
Alfasigma S.p.A.

Unknown

A Trial to Evaluate the Efficacy and Safety of PMF104 Compared to a Conventional PEG-electrolyte Solution in Children

Bowel Preparation Before Colonoscopy

Italy, Belgium, France
Limacorporate S.p.a

Completed

Fluoroscopic Analysis of Total Knee Replacement With a Kinematic Retaining or a Posterior Stabilized Design

Total Knee Replacement

Italy
SOFAR S.p.A.

Completed

Chemopreventive Action of Mesalazine on Colorectal Cancer: a Pilot Study for an "in Vivo" Evaluation of the Molecular Effects on β-catenin Signaling Pathway.

Colorectal Cancer

Italy
SOFAR S.p.A.

Completed

Efficacy Evaluation of a Commercial Preparation Containing Lactobacillus Casei DG on the Reduction of the Painful Symptoms Related to the Irritable Bowel Syndrome (IBS). A Pilot Clinical Study

Irritable Bowel Syndrome

Italy
Philogen S.p.A.

Completed

Intratumoral Application of L19IL2 in Patients With Malignant Melanoma

Malignant Melanoma

Austria, Germany
Philogen S.p.A.

Completed

131I-L19SIP Radioimmunotherapy (RIT) in Combination With External Beam Radiation in Patients With Multiple Brain Metastases From Solid Tumors

Brain Metastases From Solid Tumors

Italy, United Kingdom
SOFAR S.p.A.

Completed

Evaluation of Efficacy of Mesalamine in the Long-term Prevention of Diverticulitis Flares (DIV-01/04)

Diverticular Disease

Italy
SOFAR S.p.A.

Completed

Mesalazine Therapy in Patients With Irritable Bowel Syndrome (IBS-02/07)

Irritable Bowel Syndrome

Italy

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