Clinical Trials Sponsored by Royal Brompton & Harefield NHS Foundation Trust

Total 829 results

Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Completed

Nebulised Hypertonic Saline in Children and Young People With Neuromuscular Disease and Cerebral Palsy

Neuromuscular Diseases

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Completed

Exhaled Hydrogen Sulphide as a Biomarker of Airways Disease in Asthma

Asthma

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Withdrawn

Inhaled Corticosteroids on Airway Smooth Muscle in Asthma

Asthma

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Baylis Medical Company

Unknown

Non-fluoroscopy Ablation of AF/AT (ZERO-AF)

Atrial Tachycardia | AF - Atrial Fibrillation

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council

Completed

Is the Short Physical Performance Battery a Useful Outcome Measure in Chronic Obstructive Pulmonary Disease

Lung Diseases | Disease Progression | Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive | Pulmonary Emphysema | Bronchitis, Chronic

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Imperial College London

Completed

Minimally Invasive Endoscopy in Diffuse Lung Disease

Lung Cancer | Lung Disease
Royal Brompton & Harefield NHS Foundation Trust
Boston Scientific Corporation

Suspended

The Effect of CRT on the Hypercapnic Ventilatory Response

Heart Failure | Sleep Disordered Breathing

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Withdrawn

Macrophages in Smokers' Lung

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
University of Oxford

Unknown

Collaborative Systematic Overview of Randomised Controlled Trials of Beta-Blockers in the Treatment of Heart Failure (BB-META-HF)

Heart Failure

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council

Completed

Is Gait Speed and Sarcopenia Prognostic in Chronic Respiratory Disease?

Chronic Obstructive Pulmonary Disease and Allied Conditions

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council

Completed

Is the 4MGS a Useful Outcome Measure Post-PPCI

Acute Myocardial Infarction

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Completed

Exacerbations in Severe Asthma Patients: Mechanisms and Biomarkers

Asthma

United Kingdom
University of Cincinnati
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Pirfenidone for Progressive Fibrotic Sarcoidosis (PirFS)

Sarcoidosis, Pulmonary

United States
East and North Hertfordshire NHS Trust
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Assessment of Thrombotic Status in Patients With Atrial Fibrillation

Atrial Fibrillation
Guy's and St Thomas' NHS Foundation Trust
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

Optimisation of Mechanical Insufflation:Exsufflation (MIE2)

Neuromuscular Diseases

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Royal Brompton & Harefield NHS Foundation Trust

Unknown

FIBRotic Interstitial Lung Disease and Nocturnal OXygen (FIBRINOX)

Obstructive Sleep Apnea | Idiopathic Pulmonary Fibrosis | Sleep Disturbance | Sleep Hypoventilation

United Kingdom
East and North Hertfordshire NHS Trust
Royal Brompton & Harefield NHS Foundation Trust

Not yet recruiting

Avr Thrombosis OutcoMe Study (ATOM)

Aortic Stenosis

United Kingdom
London South Bank University
Royal Brompton & Harefield NHS Foundation Trust

Completed

Cystic Fibrosis- Children and Adults Tai Chi Study (CFCATS2)

Cystic Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Universitaire Ziekenhuizen KU Leuven

Terminated

Partial Left Ventricular Support in Advanced Heart Failure

Heart Failure | Heart-Assist Devices

Belgium, United Kingdom
ResMed
Imperial College London; Royal Brompton & Harefield NHS Foundation Trust

Completed

Mechanisms of Action of Adaptive Servoventilation

Heart Failure | Sleep Apnea Syndromes

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Bristol-Myers Squibb; Sanofi

Completed

Prospective Registry of Outcomes and Management of Acute Ischaemic Syndromes

Coronary Artery Disease | Acute Coronary Syndromes

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Kings Clinical Trials Unit

Completed

Muscle Stimulation in Advanced Idiopathic Pulmonary Fibrosis (MUST-IPF)

Idiopathic Pulmonary Fibrosis

United Kingdom
University of East Anglia
Royal Brompton & Harefield NHS Foundation Trust

Completed

The Nitrite and Coronary Flow Study

Cardiovascular Diseases | Hypoxia | Vasodilation

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Genzyme, a Sanofi Company

Unknown

Prevalence of Pompe's Disease in Respiratory Clinics (PURF)

Pompe's Disease
Royal Brompton & Harefield NHS Foundation Trust
Heidelberg University; Chelsea and Westminster NHS Foundation Trust

Withdrawn

EBUS-TBNA Versus EBUS-TBNB

Lymphoma | Carcinoma | Sarcoidosis | Mediastinal Lymphadenopathy | Hilar Lymphadenopathy | Mycobacterial Disease

United Kingdom, Germany
Chelsea and Westminster NHS Foundation Trust
Royal Brompton & Harefield NHS Foundation Trust; British Heart Foundation

Unknown

Early Cardiac Computed Tomography (CT) In Patients Admitted With Acute Chest Pain (EXACCT)

Acute Chest Pain

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Chelsea and Westminster NHS Foundation Trust; Imperial College Healthcare NHS...

Unknown

Oral Verses Patch Trial In Menopausal Women - Individualisation of Oestrogen Therapy (OPTIMISE)

Venous Thrombosis | Insulin Resistance

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Oxford University Hospitals NHS Trust; Sherwood Forest Hospitals NHS Foundation...

Unknown

Ballooned Intercostal Drain Trial

Pneumothorax | Pleural Effusion

United Kingdom
Imperial College Healthcare NHS Trust
Chelsea and Westminster NHS Foundation Trust; Royal Brompton & Harefield NHS...

Completed

Testosterone Patch's Effects on the Cardiovascular System and Libido

Hypoactive Sexual Desire Disorder

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council; The Hillingdon Hospitals NHS Foundation Trust

Terminated

Post-hospitalisation Nutritional Support and Gait Speed in COPD

Respiratory Tract Diseases | Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive | Pulmonary Emphysema | Bronchitis, Chronic

United Kingdom
Michelle Ramsay
Royal Brompton & Harefield NHS Foundation Trust

Completed

Patient -Ventilator Interaction in Chronic Respiratory Failure

Chronic Obstructive Pulmonary Disease | Obesity Hypoventilation Syndrome | Neuromuscular Disease | Chronic Hypercapnic Respiratory Failure

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College London; Royal Brompton & Harefield NHS Foundation Trust; Royal...

Recruiting

'Lung Health Check' Biomarker Study

Cancer | Lung Cancer

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; British Heart Foundation

Recruiting

Defining the Genetics, Biomarkers and Outcomes for Dilated Cardiomyopathy (Go-DCM)

Cardiovascular Diseases | Dilated Cardiomyopathy

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Imperial College London; Edwards Lifesciences

Not yet recruiting

Computational Assessment of Bioprosthetic Aortic Valve Function

Valve Heart Disease | CFD
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; Asthma UK

Completed

Airway Smooth Muscle and Asthma Severity

Asthma

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; Hill-Rom

Completed

High Frequency Chest Wall Oscillation and Cystic Fibrosis

Cystic Fibrosis

United Kingdom
National Heart and Lung Institute
Royal Brompton & Harefield NHS Foundation Trust

Completed

The Impact of Cardiac Rehabilitation Participation on Cardiac Syndrome X

Microvascular Angina

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
GlaxoSmithKline; CORDA, The Heart Charity

Unknown

Rosiglitazone Plaque Study

Vascular Diseases | Hypertension | Diabetes Mellitus, Type 2

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
King's College Hospital NHS Trust; Imperial College London

Completed

A Study of Web and Tablet-based Interactive Audiometry in Adults With CF

Cystic Fibrosis | Hearing Loss, Sensorineural

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; Royal College of Physicians

Completed

Modulation of Lung Injury Complicating Lung Resection

Acute Lung Injury

United Kingdom
Imperial College London
Swiss National Science Foundation; Royal Brompton & Harefield NHS Foundation...

Completed

Fluctuation of Airway Function in Children With Asthma

Asthma

United Kingdom
Imperial College London
Medical Research Council; Royal Brompton & Harefield NHS Foundation Trust

Completed

p38 Mitogen-Activated Protein Kinase (MAPK) and Steroid Insensitivity in Asthma

Asthma

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medtronic; British Heart Foundation; Guidant Corporation; Schneider

Completed

The Stent or Surgery (SoS) Trial

Coronary Artery Disease
Barts & The London NHS Trust
University College London Hospitals; Royal Brompton & Harefield NHS Foundation...

Completed

Bone Marrow Derived Adult Stem Cells for Dilated Cardiomyopathy (REGEN-DCM)

Dilated Cardiomyopathy

United Kingdom
Imperial College London
Medical Research Council; Royal Brompton & Harefield NHS Foundation Trust

Terminated

Transforming Growth Factor Beta Signalling in the Development of Muscle Weakness in Pulmonary Arterial Hypertension

Muscle Weakness | Pulmonary Arterial Hypertension

United Kingdom
University of Bristol
University of Oxford; Royal Brompton & Harefield NHS Foundation Trust

Completed

VIdeo Assisted Thoracoscopic Lobectomy Versus Conventional Open LobEcTomy for Lung Cancer (VIOLET)

Lung Neoplasms

United Kingdom
Monash University
Royal Brompton & Harefield NHS Foundation Trust; IM Medical Ltd, Melbourne

Completed

Alternative Risk Markers in Coronary Artery Disease (ARMCAD)

Coronary Artery Disease

Australia
Imperial College London
Novartis; Boehringer Ingelheim; Royal Brompton & Harefield NHS Foundation Trust

Completed

Regulation of the Release of Inflammatory Mediators From Lung Macrophages.

Emphysema | COPD | Chronic Bronchitis

United Kingdom
Imperial College London
Medical Research Council; Royal Brompton & Harefield NHS Foundation Trust

Completed

Investigation of the Role of FHL-1 and Myostatin in Intensive Care Unit Acquired Paresis (ICUAP)

Muscle Wasting | Intensive Care Unit Acquired Paresis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
University College London Hospitals; Guy's and St Thomas' NHS Foundation Trust

Recruiting

Connecting Breath and Mind for CYP With Long COVID

Anxiety | Post-COVID-19 Syndrome | Breathlessness

United Kingdom

Clinical Trials Sponsored by Royal Brompton & Harefield NHS Foundation Trust

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