Clinical Trials Sponsored by Scientis

Total 12643 results

Hovione Scientia Limited

Completed

Study to Evaluate the Safety and Efficacy of Minocycline Ointment in Subjects With Inflamed Meibomian Gland Dysfunction

Meibomian Gland Dysfunction | MGD-Meibomian Gland Dysfunction

United States
Hovione Scientia Limited

Completed

Study to Evaluate the Safety and Efficacy of Topical Minocycline Gel in Patients With Papulopustular Rosacea

Rosacea | Papulopustular Rosacea

United States
Kinevant Sciences GmbH
Roivant Sciences, Inc.

Completed

A Study to Assess the Efficacy and Safety of Gimsilumab in Subjects With Lung Injury or Acute Respiratory Distress Syndrome Secondary to COVID-19 (BREATHE)

COVID-19

United States
BioDelivery Sciences International
PRA Health Sciences

Completed

Single Dose Crossover Study to Compare the Respiratory Drive After Administration of Belbuca, Oxycodone and Placebo.

Respiratory Depression

United States
Dermavant Sciences GmbH

Completed

Safety and Tolerability Study of Cerdulatinib Gel, 0.37% in Adults With Vitiligo

Vitiligo

United States
Dermavant Sciences GmbH

Completed

Study of RVT-501 in Adult and Adolescent Subjects With Atopic Dermatitis

Atopic Dermatitis

Canada, United States
Dermavant Sciences GmbH

Unknown

Open-Label Study of RVT-501 Topical Ointment in Pediatric Patients With Atopic Dermatitis

Atopic Dermatitis

United States
Dermavant Sciences GmbH

Completed

A Phase 1/2 Study of E6005 in Pediatric Subjects With Atopic Dermatitis

Atopic Dermatitis

Japan
Dermavant Sciences GmbH

Completed

A Study of E6005 in Japanese Patients With Atopic Dermatitis

Atopic Dermatitis

Japan
Achieve Life Sciences
PRA Health Sciences

Completed

A Phase 2 Study Comparing Chemotherapy in Combination With OGX-427 or Placebo in Patients With Bladder Cancer

Urologic Neoplasms | Metastatic Bladder Cancer | Urinary Tract Neoplasms

Spain, United States, Canada, Italy, Poland, Germany, France
Light Sciences Oncology

Completed

Tumor Ablation With Talaporfin Sodium and Interstitial Light Emitting Diodes Treating Hepatocellular Carcinoma (HCC)

Carcinoma, Hepatocellular | Liver Neoplasms

Taiwan, Hong Kong, Singapore
Gilead Sciences

Not yet recruiting

A Study to Provide Continued Access to Study Drug to Children and Adolescents Who Have Completed Clinical Studies Involving Gilead HIV Treatments

HIV-1-infection
Gilead Sciences

Recruiting

Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With Biktarvy (ARTISTRY-2)

HIV-1-infection

United States, Puerto Rico
Gilead Sciences

Recruiting

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis (SWIFT)

Ulcerative Colitis

United States
Gilead Sciences

Recruiting

Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors

Solid Tumors

Australia, United States, Canada
Gilead Sciences

Recruiting

Study of Bulevirtide in Participants Who Have Normal or Impaired Liver Function

Chronic Hepatitis D Infection

United States
Gilead Sciences

Recruiting

Study of Bulevirtide in Participants With Chronic Hepatitis D Infection

Chronic Hepatitis D Infection

Austria, Spain, France, Germany, Romania
Gilead Sciences

Recruiting

Study of Novel Antiretrovirals in Participants With HIV-1

HIV-1-infection

United States, Thailand, Dominican Republic
Ad scientiam

Recruiting

Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD (OPTIS)

Neuromyelitis Optica

United States, France
Gilead Sciences

Completed

Study to Evaluate the Pharmacokinetics (PK), Safety, and Efficacy of B/F/TAF in Human Immunodeficiency Virus (HIV)-1 Infected, Virologically Suppressed, Pregnant Women in Their Second and Third Trimesters

HIV-1-infection

United States, Dominican Republic, Thailand
Gilead Sciences

Active, not recruiting

Study of Sacituzumab Govitecan in Participants With Metastatic Solid Tumors (TROPiCS-03)

Metastatic Solid Tumor

United States, Spain, France, Hong Kong, Australia, Belgium, Taiwan, Canada
Gilead Sciences

Active, not recruiting

Study of Magrolimab Given Together With FOLFIRI/BEV in Patients With Previously Treated Advanced Inoperable Metastatic Colorectal Cancer (mCRC) (ELEVATE CRC)

Metastatic Colorectal Cancer

United States, Spain, Australia, Hong Kong, France, Belgium, Canada, Puerto Rico, Germany, Italy
Gilead Sciences

Terminated

Study of Magrolimab Versus Placebo in Combination With Venetoclax and Azacitidine in Participants With Acute Myeloid Leukemia (ENHANCE-3)

Acute Myeloid Leukemia

United States, Spain, Germany, Israel, United Kingdom, Taiwan, Korea, Republic of, Australia, Belgium, Hong Kong, France, Netherlands, Italy, Canada, Austria, Czechia, Hungary, Norway, Poland, Switzerland
Gilead Sciences

Completed

Study of Magrolimab Combinations in Participants With Myeloid Malignancies

Myeloid Malignancies

United States, Australia, United Kingdom
Gilead Sciences

Terminated

Magrolimab + Azacitidine Versus Azacitidine + Placebo in Untreated Participants With Myelodysplastic Syndrome (MDS) (ENHANCE)

Myelodysplastic Syndromes

United States, Spain, Belgium, Australia, France, Hong Kong, Hungary, Finland, New Zealand, Germany, Netherlands, United Kingdom, Italy, Switzerland, Portugal, Canada, Austria, Czechia, Norway, Poland, Turkey
Gilead Sciences

Completed

Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Disoproxil Fumarate in Treatment Naive, HIV-1 and Hepatitis B Co-Infected Adults (Alliance)

HIV-1/HBV Co-Infection

Spain, Taiwan, Korea, Republic of, Thailand, Hong Kong, Japan, France, Turkey, Puerto Rico, Malaysia, United States, China, Dominican Republic, Greece
Gilead Sciences

Active, not recruiting

Study of Magrolimab Combination Therapy in Patients With Non-Surgically Removable Locally Advanced or Metastatic Triple-Negative Breast Cancer (ELEVATE TNBC)

Triple-Negative Breast Cancer

United States, United Kingdom, Australia, Hong Kong, Korea, Republic of, Taiwan
Gilead Sciences

Active, not recruiting

Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Single Tablet Regimen (STR) in HIV-1 Infected Antiretroviral Treatment-Naive Adolescents and Virologically Suppressed Children

HIV Infections | Acquired Immune Deficiency Syndrome (AIDS)

United States, Thailand, Uganda, South Africa, Zimbabwe
Gilead Sciences

Active, not recruiting

Pre-Exposure Prophylaxis Study of Lenacapavir and Emtricitabine/Tenofovir Alafenamide in Adolescent Girls and Young Women at Risk of HIV Infection (PURPOSE 1)

Pre-Exposure Prophylaxis of HIV Infection

South Africa, Uganda
Gilead Sciences

Active, not recruiting

Study to Evaluate the Safety and Efficacy of Lenacapavir (GS-6207) in Combination With an Optimized Background Regimen (OBR) in Heavily Treatment Experienced Participants Living With HIV-1 Infection With Multidrug Resistance (CAPELLA)

HIV-1-infection

United States, Spain, France, Taiwan, Japan, Thailand, Dominican Republic, Germany, Canada, Italy, South Africa
Gilead Sciences

No longer available

US Expanded Access Program for Magrolimab in Patients With Relapsed or Refractory Acute Myeloid Leukemia

Relapsed/Refractory Acute Myeloid Leukemia
Gilead Sciences

Terminated

Study to Evaluate the Safety and Efficacy of KITE-439 in HLA-A*02:01+ Adults With Relapsed/Refractory HPV16+ Cancers

Human Papillomavirus (HPV) 16+ Relapsed/Refractory Cancer

United States
Gilead Sciences

Terminated

Study of Dalutrafusp Alfa (Formerly GS-1423) in Participants With Advanced Solid Tumors

Advanced Solid Tumors

United States
Gilead Sciences

Completed

Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Negative Hepatitis B (China)

HBV | Chronic HBV Infections

China
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Teropavimab and Zinlirvimab in Combination With Lenacapavir (GS-6207) in Virologically Suppressed Adults With HIV-1 Infection

HIV-1 Infection

United States
Gilead Sciences

Active, not recruiting

Study to Assess Efficacy and Safety of Bulevirtide in Participants With Chronic Hepatitis Delta (CHD)

Chronic Hepatitis Delta

Germany, Russian Federation, United States, Italy, Sweden
Gilead Sciences

Terminated

Safety and Tolerability of Cilofexor in Participants With Primary Sclerosing Cholangitis (PSC) and Compensated Cirrhosis

Primary Sclerosing Cholangitis | Compensated Cirrhosis

United States
Alimera Sciences

Active, not recruiting

A Study of Intravitreal ILUVIEN® Implant as Baseline Therapy in Patients With Early Diabetic Macular Edema (DME) (NEW DAY)

Diabetic Macular Edema

United States
Gilead Sciences

Terminated

Study of GS-0189 (Formerly FSI-189) as Monotherapy and in Combination With Rituximab in Participants With Relapsed/Refractory Non-Hodgkin Lymphoma

Non-hodgkin Lymphoma

United States
Gilead Sciences

Completed

Study to Assess Efficacy and Safety of Bulevirtide in Combination With Pegylated Interferon Alfa-2a in Participants With Chronic Hepatitis Delta (CHD)

Chronic Hepatitis Delta

France, Moldova, Republic of, Romania, Russian Federation
Gilead Sciences

Terminated

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of GS-3583 in Participants With Advanced Solid Tumors

Advanced Solid Tumors

United States
Gilead Sciences

Terminated

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Evixapodlin (Formerly GS-4224) in Participants With Advanced Solid Tumors

Advanced Solid Tumors

United States, New Zealand
Gilead Sciences

Terminated

Study to Evaluate the Efficacy and Safety of Tilpisertib in Adults With Moderately to Severely Active Ulcerative Colitis (Falcon)

Ulcerative Colitis

United States, France, Australia, Italy, Poland, Germany, Austria, Canada, Switzerland
Origin Sciences

Completed

Exploratory Study of Rectal Mucus for Diagnosing Disease (ORI-EGI-02)

Bowel Cancer | Bowel Disease | Epigenetic Disorder | Genomic

United Kingdom
Gilead Sciences

Withdrawn

Study to Evaluate Safety, Tolerability, and Efficacy of GS-5718 in Participants With Active Rheumatoid Arthritis Who Have an Inadequate Response to Disease-modifying Antirheumatic Drug(s) (bDMARDs) Treatment

Rheumatoid Arthritis
Gilead Sciences

Completed

Study to Investigate the Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination for 12 Weeks in Adults With Chronic HCV Infection and Compensated Cirrhosis

Hepatitis C Virus Infection

Japan
Gilead Sciences

Completed

Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis (NASH) | Nonalcoholic Fatty Liver Disease (NAFLD)

United States, New Zealand
Gilead Sciences

Completed

Study in Participants With Early Stage Coronavirus Disease 2019 (COVID-19) to Evaluate the Safety, Efficacy, and Pharmacokinetics of Remdesivir Administered by Inhalation

COVID-19

United States
Alimera Sciences

Completed

Phase 4 IOP Signals Associated With ILUVIEN® (PALADIN)

Diabetic Macular Edema (DME)

United States
Gilead Sciences

Completed

Harvoni in Patients With Chronic Hepatitis C Virus (HCV) Infection in Korea

Hepatitis C Virus

Korea, Republic of

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