Clinical Trials Sponsored by Singapore Institute for Clinical Sciences

Total 2373 results

Singapore Institute for Clinical Sciences

Recruiting

Postbiotic Intervention for Acute Stress Management (PIAS)

Sleep | Stress Response | Cognition | Mood State

Singapore
Singapore Institute for Clinical Sciences

Completed

A Decentralized Study on Dietary Influences on Cognitive Functions

Cognitive Function | Glucose Metabolism

Singapore
Singapore Institute for Clinical Sciences

Completed

Evaluating the Metabolic Effects of Dietary Nitrate Supplementation (NIMMI)

Dietary Nitrate Supplementation

Singapore
Singapore Institute for Clinical Sciences

Completed

Investigating Inter-individual Variability in Glycemic and Insulin Responses

Hyperglycemia | Insulin Sensitivity

Singapore
Singapore Institute for Clinical Sciences

Recruiting

Identifying Molecular Determinants of Infertility in Men (MODIFY)

Male Infertility

Singapore
Singapore Institute for Clinical Sciences

Recruiting

Harnessing Human Potential and Improving Health Span in Women and Their Children (HAPPY)

Type 2 Diabetes | Gestational Diabetes | Healthy Lifestyle Behaviors

Singapore
Clinical Nutrition Research Centre, Singapore
Singapore Institute for Clinical Sciences

Completed

Insulin Modelling Based on Plasma Glucose Measures Via a Minimally-Invasive Glucose Sensor

PreDiabetes

Singapore
Singapore Institute for Clinical Sciences
National University of Singapore

Completed

The Appetite Toolbox for Preschools

Body Weight | Eating Behavior | Self Regulation

Singapore
Nestlé
Singapore Institute for Clinical Sciences; National Heart Centre Singapore

Completed

ARROW:identificAtion of postpRandial biomaRkers tOWards Cardiovascular Prevention

Cardiovascular Diseases

Switzerland
Singapore Institute for Clinical Sciences
National University Polyclinics, Singapore; National University of Singapore

Completed

A Mobile Health-enabled Lifestyle Intervention Among Women With History of Gestational Diabetes(GDM) (Reverse-DM)

Healthy | Diabetes, Gestational | Gestational Diabetes Mellitus in Pregnancy

Singapore
Singapore Institute for Clinical Sciences
OBVIO HEALTH USA, Inc.

Recruiting

Novel Objective Digital Biomarkers for Assessing Sub-clinical Mood Disturbances in the Singaporean Population

Mood

Singapore
Singapore Institute for Clinical Sciences
DSM Nutritional Products, Inc.

Completed

Beta-cryptoxanthin Supplement: Absorption and Function (BETA+)

Beta-cryptoxanthin Supplementation

Singapore
KK Women's and Children's Hospital
Singapore Institute for Clinical Sciences

Unknown

Impact of Perinatal Anaesthesia and Analgesia on Neurocognitive Outcomes in Early Childhood (PANO)

Anaesthesia | Neurodevelopment

Singapore
KK Women's and Children's Hospital
Singapore Institute for Clinical Sciences

Active, not recruiting

Exposure to General Anaesthesia in Infancy and Neurocognitive Development (EGAIN)

Impaired Cognition | Central Nervous System Complications of Anesthesia

Singapore
Duke-NUS Graduate Medical School
Singapore Institute for Clinical Sciences

Completed

Satiety Effects on the Neural Valuation of Food

Fasting | Fed

Singapore
National University Hospital, Singapore
KK Women's and Children's Hospital; Singapore Institute for Clinical Sciences

Active, not recruiting

Growing Up in Singapore Towards Healthy Outcomes (GUSTO)

Metabolic Diseases | Neurological and Mental Health Conditions

Singapore
Singapore Institute for Clinical Sciences
National University Polyclinics, Singapore; Wilmar International Limited; SATA... and other collaborators

Completed

Ectopic Fat in Singaporean Women - the Culprit Leading to Gestational Diabetes, Metabolic Syndrome, and Type 2 Diabetes (TANGO Study) (TANGO)

Non-Alcoholic Fatty Liver Disease

Singapore
Singapore Institute for Clinical Sciences
Almond Board of California; National Medical Research Foundation (NMRC) Singapore

Completed

Asian Indian Prediabetes Study (AIPS)

Pre Diabetes

Singapore
KK Women's and Children's Hospital
Singapore Institute for Clinical Sciences; National University Health System...

Active, not recruiting

Singapore PREconception Study of Long-Term Maternal and Child Outcomes

Metabolic Disease | Neurological and Mental Health Conditions

Singapore
Institute for Clinical Evaluative Sciences

Completed

Invasive Coronary Angiography Early in Ischemic Heart Failure (ICE-HF)

Acute Heart Failure

Canada
Institute for Clinical Evaluative Sciences

Unknown

Ontario Printed Educational Materials (PEMs) for Physician Behaviour Change (OPEMS)

Hypertension | Diabetes Mellitus, Type 2 | Education, Medical, Continuing | Practice Patterns
Institute for Clinical Evaluative Sciences

Completed

Comparison of Outcomes and Access to Care for Heart Failure Trial (COACH)

Heart Failure

Canada
Institute for Clinical Evaluative Sciences

Completed

Acute Congestive Heart Failure Urgent Care Evaluation (ACUTE)

Heart Failure

Canada
Institute for Clinical Evaluative Sciences

Completed

Promoting Blood Pressure Control and Cholesterol Reduction to Prevent Major Complications in Persons With Diabetes

Diabetes

Canada
Singapore General Hospital
Singapore Clinical Research Institute

Unknown

Arteriovenous Fistula: Conventional Angioplasty vs Drug Eluting Balloon-assisted Maturation Intervention Clinical Trial (ACADEMIC)

Stenosis of Arteriovenous Dialysis Fistula
Singapore General Hospital
Singapore Clinical Research Institute

Terminated

Vancomycin Versus Daptomycin for the Treatment of Methicillin Resistant Staphylococcus Aureus (MRSA) Bacteremia

Bacteremia Due to Staphylococcus Aureus

Singapore
Institute of Mental Health, Singapore
Singapore Clinical Research Institute

Completed

Lofexidine for Inpatient Opiate Detox in Singapore

Opiate Dependent Patients Who Are Undergoing Inpatient Detoxification in Singapore

Singapore
Clinical Nutrition Research Centre, Singapore
Institute for Infocomm Research

Completed

BRown Fat Activity Measurement With Infrared imaginG tHermography andThermogenesis - the BRIGHT Study (BRIGHT)

Obesity | Energy Expenditure | Adipose Tissue, Brown
University of Southampton
National University Hospital, Singapore; Singapore Institute for Clinical Sciences and other collaborators

Completed

Nutritional Intervention Preconception and During Pregnancy to Maintain Healthy Glucose Metabolism and Offspring Health (NiPPeR)

Hyperglycemia

Singapore, United Kingdom, New Zealand
National University Hospital, Singapore
Singapore Clinical Research Institute

Active, not recruiting

End-of-Life Management Protocol Offered Within Emergency Room: a Multicentre Study (EMPOWER) (EMPOWER)

Palliative Care | Emergency Department | Cost Effectiveness

Singapore
National Cancer Centre, Singapore
Singapore Clinical Research Institute

Completed

Prospective Cohort Study on the Clinical Trajectory of Resected Hepatocellular Carcinoma (PLANET)

Hepatocellular Carcinoma

Singapore, Malaysia, Philippines, Thailand
National University Hospital, Singapore
Singapore Clinical Research Institute

Completed

Emergency Department Management of Sepsis Patients: A Goal-Oriented Non-Invasive Sepsis Trial (AGONIST)

Sepsis | Shock, Septic

Singapore
Clinical Nutrition Research Centre, Singapore
Agency for Science, Technology and Research

Completed

The Role of Thyroid Status in Regulating Brown Adipose Tissue Activity, White Adipose Tissue Partitioning and Resting Energy Expenditure (TRIBUTE)

Hyperthyroidism

Singapore
Sunnybrook Health Sciences Centre
Institute for Clinical Evaluative Sciences

Completed

Evaluation of a Toolkit to Improve Cardiovascular Disease Screening and Treatment for People With Diabetes

Cardiovascular Disease | Diabetes Mellitus

Canada
University of Auckland, New Zealand
Singapore Institute for Clinical Sciences; Massey University; AgResearch; The Riddet...

Completed

Acute Meat and Alternative Intake (PRotEin DIet SatisfacTION Trial 3) (PREDITION)

Diet, Healthy | Protein; Disease

New Zealand
Duke-NUS Graduate Medical School
Singapore General Hospital; Agency for Science, Technology and Research; Singapore... and other collaborators

Completed

Effectiveness of a Brain-Computer Interface Based System for Cognitive Enhancement in the Normal Elderly (3ECog)

Dementia | Mild Cognitive Impairment | Alzheimer's Disease | Age-Related Cognitive Decline

Singapore
KK Women's and Children's Hospital
Singapore Institute for Clinical Sciences; Duke-NUS Graduate Medical School

Recruiting

Integrated Hyperglycaemia Incentivised Postnatal Surveillance Study (I-HIPS) (I-HIPS)

Glucose Metabolism Disorders | Gestational Diabetes | Metabolic Disease

Singapore
National University Hospital, Singapore
AstraZeneca; Singapore Clinical Research Institute

Unknown

Phase II Study of AZD9291 in Advanced Stage NSCLC With EGFR and T790M Mutations Detected in Plasma Ct-DNA (PLASMA)

Carcinoma, Non-Small-Cell Lung

Taiwan, Hong Kong, Thailand, Singapore, Korea, Republic of
National Healthcare Group, Singapore
Duke-NUS Graduate Medical School; Agency for Science, Technology and Research; Singapore Clinical Research Institute

Completed

Brain-Computer Interface (BCI) Based Intervention for Attention Deficit Hyperactivity Disorder (ADHD)

Attention Deficit Hyperactivity Disorder

Singapore
The Hospital for Sick Children
Institute for Clinical Evaluative Sciences

Completed

Evaluating the Effect of Surgical Safety Checklists on Perioperative Complications in Children

Postoperative Complications | Intraoperative Complications

Canada
Singapore Institute for Clinical Sciences
Duke-NUS Graduate Medical School; Canadian Imaging Research Centre (CIRC); Singapore... and other collaborators

Recruiting

Brown Fat Activation and Browning Efficiency Augmented by Chronic Cold and Nutraceuticals for Brown Adipose Tissue-mediated Effect Against Metabolic Syndrome (BEACON BEAMS Study)

Obesity | Energy Expenditure | Brown Adipose Tissue

Singapore
National Research Foundation, Singapore
Duke University; National University, Singapore; Singapore Clinical Research...

Completed

Study of a Neurocognition Enhancing Agent in Patients With Schizophrenia

Schizophrenia

Singapore
National Cancer Centre, Singapore
Singapore Translational Cancer Consortium; Genome Institute of Singapore; Cancer...

Recruiting

Phase-2 Dacomitinib Study on Patients With EGFR-Driven Advanced Solid Tumours With Low EGFR-AS1 IncRNA Expr or Other Novel Emerging Biomarkers

Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Advanced Solid Tumours

Singapore
University of Southampton
National University Hospital, Singapore; Singapore Institute for Clinical Sciences and other collaborators

Enrolling by invitation

NiPPeR Randomised Trial - Child Follow Up Study (NiPPeR Child)

Neurobehavioral Manifestations | Allergy | Microbial Colonization | Growth Disorders | Atopic Dermatitis | Obesity, Childhood | Metabolic Disturbance | Cognition | Lifestyle | Breastfeeding | Nutrition, Healthy | Atopy

Singapore, United Kingdom, New Zealand
Singapore General Hospital
Whitehead Institute for Biomedical Research; Blood Services Group, Health Sciences...

Terminated

Clinical Ex Vivo Expansion of Human Umbilical Cord Blood Stem and Progenitor Cells

Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Myeloma | Chronic Leukemia

Singapore
National University Hospital, Singapore
The N.1 Institute for Health (N.1); Cancer Science Institute of Singapore

Not yet recruiting

Optimizing and Personalising Azacitidine Combination Therapy for Treating Solid Tumours QPOP and CURATE.AI

Breast Cancer | Solid Tumor | Gastrointestinal Cancer

Singapore
Duke-NUS Graduate Medical School
Singapore General Hospital; Tan Tock Seng Hospital; National University, Singapore and other collaborators

Completed

Brain-Computer Interface System for Training Memory and Attention in Elderly

Dementia | Mild Cognitive Impairment | Alzheimer's Disease | Age-Related Cognitive Decline

Singapore
KK Women's and Children's Hospital
Singapore Institute for Clinical Sciences; Duke-NUS Graduate Medical School; Singhealth...

Completed

Dexmedetomidine Sedation Versus General Anaesthesia for Inguinal Hernia Surgery in Infants (DEGA)

Neurodevelopmental Disorder | Bilateral Inguinal Hernia

Singapore
Sunnybrook Health Sciences Centre
Ottawa Hospital Research Institute; Institute for Clinical Evaluative Sciences

Active, not recruiting

The Link Between Clinical and Physiological Sleep Data and Health-related Outcomes

Cardiovascular Diseases | Sleep Apnea Syndromes | Cancer | Mortality | Sleep Initiation and Maintenance Disorders | Hospitalizations | Nocturnal Myoclonus Syndrome

Canada
Asia Cornea Society
Singapore Clinical Research Institute

Unknown

The Asia Cornea Society Infectious Keratitis Study (ACSIKS)

Corneal Ulcer

Singapore, China, India, Japan, Korea, Republic of, Philippines, Taiwan, Thailand

Clinical Trials Sponsored by Singapore Institute for Clinical Sciences

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kenya

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Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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