Clinical Trials Sponsored by Sintesi Research S.r.l.

Total 86 results

Mastelli S.r.l
Sintesi Research Srl

Terminated

Efficacy and Safety of PLACENTEX ® i.m. in Patients With Scleroderma Diseases

Scleroderma Disease

Italy
CMR Surgical Ltd
Liverpool University Hospitals NHS Foundation Trust; Sintesi Research S.r.l.

Recruiting

Prospective Clinical Study to Assess the Safety and Efficacy of Versius, in Transoral Robotic Surgery

Squamous Cell Carcinoma of the Oropharynx | Squamous Cell Carcinoma, Unknown Primary

United Kingdom
Alfa Intes Industria Terapeutica Splendore s.r.l.

Not yet recruiting

Idroflog® for Treatment of Dry Eye Disease (IDROFLOG) (IDROFLOG)

Dry Eye Disease

France
Sintetica SA
Sintesi Research Srl

Completed

Observational Study on 2-chloroprocaine Hydrochloride 1% (PASS)

Neurological Complication, in Particular TNS or CES

Belgium
SIFI SpA
Sintesi Research Srl

Completed

Clinical Study to Evaluate the Efficacy and Tolerability of an Anti-inflammatory/Antibiotic Treatment Following Ocular Cataract Extraction

Cataract | Cataract Extraction

Italy, Romania, Germany
Indena S.p.A
Sintesi Research Srl

Withdrawn

Tolerability, Safety and Activity of a Muscle Relaxant Molecule IDN5243 in Patients With Low Back Pain (IDN5243inLBP)

Low Back Pain

Italy
Virility Medical Ltd.
Sintesi Research Srl

Completed

Evaluation of the Safety and Effectiveness of the vPatch Device

Premature Ejaculation

Israel, Italy
Aqueduct Medical Ltd
Sintesi Research Srl

Completed

Effectiveness and Safety Evaluation of Aqueduct -100 Device

Cervix Uteri Dilation

Italy
NicOx Research Institute S.r.l.

Completed

Effect of NCX4016 on Walking Distance in Patients With Peripheral Arterial Occlusive Disease (PAOD)

Intermittent Claudication

Italy
Fondazione Angelo Bianchi Bonomi
Sintesi Research Srl

Active, not recruiting

Type 3 Von Willebrand International Registries Inhibitor Prospective Study (3WINTERSIPSEXT)

Type 3 Von Willebrand's Disease

Finland, France, Germany, Hungary, Iran, Islamic Republic of, Italy, Netherlands, Spain, Sweden, United Kingdom
Fondazione Angelo Bianchi Bonomi
Sintesi Research Srl

Completed

Survey of Inhibitors in Plasma-Product Exposed Toddlers (SIPPET)

Hemophilia A

United States, India, Spain, Argentina, Austria, Brazil, Chile, Egypt, Iran, Islamic Republic of, Italy, Mexico, Saudi Arabia, South Africa, Turkey
Indena S.p.A
Istituto Superiore di Sanità; Sintesi Research Srl

Recruiting

Effect of Nutritional Supplementation With Turmeric on the Cognitive Performance of Subjects With Metabolic Syndrome (EPICURO)

Mild Cognitive Impairment

Italy
Consorzio Oncotech
Clinical Research Technology S.r.l.

Unknown

Safety and Efficacy Study of Eribulin in Combination With Bevacizumab for Second-line Treatment HER2- MBC Patients (GIM11-BERGI)

Metastatic Breast Cancer | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast

Italy
Consorzio Oncotech
Clinical Research Technology S.r.l.

Unknown

Fulvestrant and EVerolimus Plus EXemestane in Metastatic Breast Cancer (FEVEX)

Breast Cancer | Metastatic Breast Cancer | Hormone Receptor Positive Tumor | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Locally Advanced Malignant Neoplasm

Italy
Consorzio Oncotech
Clinical Research Technology S.r.l.

Unknown

Fulvestrant as Maintenance Therapy After First-line Chemotherapy in HER2 - Postmenopausal MBC Patients (FUMANCE)

Metastatic Breast Cancer

Italy
Consorzio Oncotech
Clinical Research Technology S.r.l.

Recruiting

Avelumab Plus Intermittent Axitinib in Previously Untreated Patients With Metastatic Renal Cell Carcinoma (TIDE-A)

Renal Carcinoma Metastatic

Italy
Consorzio Oncotech
Clinical Research Technology S.r.l.

Unknown

Safety and QoL of Trastuzumab With Lapatinib or Chemiotherapy in MBC and HER2+ Patients Refractory to Anti HER2 Therapies

Metastatic Breast Cancer

Italy
Consorzio Oncotech
Clinical Research Technology S.r.l.

Unknown

Observation of Medical Treatments in MBC HER2-negative Patients (AMBRA)

Metastatic Breast Cancer

Italy
Neupharma Srl
Sintesi Research Srl; Pari Pharma GmbH; Aptuit

Completed

Open-label, Dose-escalation Study to Evaluate the Pharmacokinetics of Inhaled Teicoplanin in Cystic Fibrosis Patients

Cystic Fibrosis

Italy
Sealantium Medical Ltd.
Sintesi Research Srl; Home Medics Consulting Ltd.

Completed

A Study Evaluating the Safety and Preliminary Efficacy of sFilm-FS in Controlling Parenchymal Bleeding During Elective Hepatic Surgery

General Surgery | Hemostasis

Austria, United States, Slovenia
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
Sintesi Research Srl

Unknown

Safety/Efficacy Study to Assess Whether FVIII/VWF Concentrate Can Induce Immune Tolerance in Haemophilia A Patients (ITI)

Hemophilia A

India, Egypt
AM-Pharma
CRM Biometrics GmbH; Sintesi Research Srl; Vigilex BV

Completed

Safety/Efficacy Study of Bovine Intestinal Alkaline Phosphatase in Patients With Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

Czech Republic, Italy
Fondazione Melanoma Onlus
Clinical Research Technology S.r.l.

Active, not recruiting

Sequential Combo Immuno and Target Therapy (SECOMBIT) Study (SECOMBIT)

Metastatic Melanoma

Italy, Germany, Spain, Greece, Austria, France, Poland, Sweden, Switzerland, United Kingdom
Fondazione Sandro Pitigliani
Clinical Research Technology S.r.l.

Recruiting

To Identify Primary Resistance to CDK4/6 Inhibitors in Breast Cancer (TIRESIAS)

Metastatic Breast Cancer | HER2-negative Breast Cancer | ER Positive Breast Cancer

Italy
Mario Negri Institute for Pharmacological Research
Fondazione Bruno Kessler; Astir S.r.l.; Orobix Life S.r.l.

Not yet recruiting

Development of a Multipurpose Dashboard to Monitor the Situation of Emergency Departments (eCREAM-UC2)

Emergency Medicine
Fondazione Melanoma Onlus
Clinical Research Technology S.r.l.

Active, not recruiting

Combination or Sequence of Vemurafenib, Cobimetinib, and Atezolizumab in High-risk, Resectable Melanoma (NEO-TIM)

Melanoma

Italy
Fondazione Ricerca Traslazionale
Clinical Research Technology S.r.l.

Unknown

An Open-label, Randomized, Parallel, Non Comparative, Phase II Trial of Nivolumab Plus Ipilimumab Versus Platinum-based Chemotherapy Plus Nivolumab in Chemonaive Metastatic or Recurrent Squamous-Cell Lung Cancer (SqLC) (SQUINT)

Squamous-Cell Lung Cancer

Italy
Laboratorios Ordesa
OPBG Clinical & Research Services S.R.L.

Completed

Study to Assess Hypoallergenicity of a New Amino-acid Based Infant Formula in Children With Cow's Milk Allergy (RAF)

Cow's Milk Allergy

Italy
Mario Negri Institute for Pharmacological Research
Fondazione Bruno Kessler; Astir S.r.l.; Orobix Life S.r.l.

Not yet recruiting

Development of a Natural Language Processing Tool to Enable Clinical Research in Emergency Medicine (NLP-DeVal)

Emergency Medicine

Italy
Toscana Life Sciences Sviluppo s.r.l.
Cross Research S.A.

Completed

Study to Evaluate the Safety and Concentrations of Monoclonal Antibody Against Virus That Causes COVID-19 Disease. (MAD0004J08)

COVID-19 Virus Disease

Italy
Consorzio Oncotech
Quercegen Pharmaceuticals; Clinical Research Technology S.r.l.

Unknown

Isoquercetin as an Adjunct Therapy in Patients With Kidney Cancer Receiving First-line Sunitinib: a Phase I/II Trial (QUASAR)

Kidney Cancer | Renal Cell Carcinoma

Italy
University of Oslo
SINTEF Health Research

Completed

Integrated Treatment to Persons With Mental Disorders and Co-occurring Substance Use Disorders (ROP)

Mood Disorders | Anxiety Disorders | Substance Use Disorders
Mario Negri Institute for Pharmacological Research
Bio3 Research s.r.l. - Milan Italy

Completed

L-Cysteine in Peritoneal Dialysis (CINDY)

Uremia

Italy
Mario Negri Institute for Pharmacological Research
Centre Hospitalier Universitaire Vaudois; Fondazione Bruno Kessler; Astir S.r.l. and other collaborators

Not yet recruiting

Propensity to Hospitalize Patients From the ED in European Centers. (eCREAM-UC1)

Emergency Medicine
Azienda Ospedaliera Città della Salute e della...
Consoft Sistemi S.p.A. Turin, Italy; Caretek S.r.l. Turin, Italy

Unknown

Validation of the ADAMO Watch for the Early Detection of Fall Events in Older Patients (ADAMO)

Accidental Falls | Wearable Electronic Devices

Italy
Norwegian Institute of Public Health
SINTEF Health Research

Active, not recruiting

Air Purifiers in Classrooms for Infection Control - a Pilot Study

Feasibility | Acceptability

Norway
Mario Negri Institute for Pharmacological Research
Otsuka Pharmaceutical Italy S.r.l.

Completed

Tolvaptan-Octreotide LAR Combination in ADPKD (TOOL)

Autosomal Dominant Polycystic Kidney Disease

Italy
Mario Negri Institute for Pharmacological Research
Alexion Pharma Italy s.r.l.

Completed

Eculizumab in Primary MPGN (EAGLE)

Membranoproliferative Glomerulonephritis

Italy
CUTISS AG
University of Zurich; University Hospital, Zürich; Julius Clinical; Sintesi Research... and other collaborators

Active, not recruiting

Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents

Burns

Switzerland, Netherlands, Italy
CUTISS AG
University of Zurich; University Hospital, Zürich; Julius Clinical; Sintesi Research... and other collaborators

Active, not recruiting

Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Full-Thickness Skin Defects in Adults and Children

Skin Wound

Switzerland, Italy, Netherlands
CUTISS AG
University of Zurich; University Hospital, Zürich; Julius Clinical; Sintesi Research... and other collaborators

Recruiting

Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Children

Burns

Switzerland, Italy, Netherlands
Universidade Nova de Lisboa
CINTESIS - Center for Health Technology and Services Research

Recruiting

The Effect of Natural Carbonated Mineral Water Consumption on Gastrointestinal Transit and on Gut Microbiota in Subjects With Functional Constipation: A Randomized, Placebo-Controlled Pilot Trial

Functional Constipation

Portugal
Norwegian University of Science and Technology
St. Olavs Hospital; SINTEF Health Research

Recruiting

Virtual Surgery of the Upper Airways (VirtuOSA)

Sleep Apnea, Obstructive

Norway
Norwegian University of Science and Technology
St. Olavs Hospital; SINTEF Health Research

Completed

Effect of 3 Years of Exercise in Patients With Atrial Fibrillation

Atrial Fibrillation

Norway
Norwegian University of Science and Technology
St. Olavs Hospital; SINTEF Health Research

Terminated

Contrast-enhanced Ultrasound in Follow-up After Endovascular Aneurysm Repair

Abdominal Aortic Aneurysm | Endoleak

Norway
Norwegian University of Science and Technology
St. Olavs Hospital; SINTEF Health Research

Completed

Endoleak Repair Guided by Navigation Technology

Aortic Aneurysm | Endoleak

Norway
Norwegian University of Science and Technology
St. Olavs Hospital; SINTEF Health Research

Completed

Aerobic Interval Training in Patients With Atrial Fibrillation

Atrial Fibrillation

Norway
St. Olavs Hospital
Norwegian University of Science and Technology; SINTEF Health Research

Completed

Navigated EBUS and Functional Imaging in Lung Cancer

Bronchial Neoplasms

Norway
Norwegian University of Science and Technology
St. Olavs Hospital; SINTEF Health Research

Suspended

Evaluation of a New Open Source Virtual Bronchoscope Navigation System

Bronchial Neoplasms

Norway
Norwegian University of Science and Technology
St. Olavs Hospital; SINTEF Health Research

Completed

Manual Compared to Magnetic Navigation in Ablation for Atrial Fibrillation

Atrial Fibrillation

Norway

Clinical Trials Sponsored by Sintesi Research S.r.l.

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