Clinical Trials Sponsored by Sylentis, S.A

Total 3168 results

Sylentis, S.A.

Completed

SYL040012. Tolerance and Effect on Intraocular Pressure in Subjects With Intraocular Pressure (IOP) >= 21 mm Hg

Ocular Hypertension | Glaucoma

Spain
Sylentis, S.A.

Completed

Tolerance and Effect on Intraocular Pressure After Administration of SYL040012

Ocular Hypertension | Glaucoma

Spain
Sylentis, S.A.

Completed

Safety Study of Tivanisiran to Treat Dry Eye (FYDES)

Dry Eye Disease

United States
Sylentis, S.A.

Completed

Dose Finding Clinical Trial With SYL040012 to Evaluate the Tolerability and Effect on Intraocular Pressure in Subjects With Ocular Hypertension or Open Angle Glaucoma

Ocular Hypertension | Open Angle Glaucoma

Spain, Germany, Estonia
Sylentis, S.A.

Completed

Study to Evaluate the Ocular Tolerance of SYL1001 in Healthy Volunteers

Dry Eye | Ocular Pain

Spain
Sylentis, S.A.

Recruiting

A Randomized, Double Masked, Parallel Group, Dose-finding Study to Evaluate SYL1801 in Patients With Neovascular Age-related Macular Degeneration (AMD)

Macular Degeneration | Wet Macular Degeneration | Neovascular Age-related Macular Degeneration

Czechia, Slovakia, Poland
Sylentis, S.A.

Completed

Tivanisiran for Dry Eye in Subjects With Sjögren's Syndrome

Dry Eye Disease | Sjögren Syndrome

United States, Spain
Sylentis, S.A.

Completed

Safety, Tolerability and Pharmacokinetic Profile of SYL1801 Eye Drops

Choroidal Neovascularization | Safety, Tolerability and Pharmacokinetic Profile in Healthy Volunteers

Spain
Sylentis, S.A.

Completed

SYL040012, Treatment for Open Angle Glaucoma (SYLTAG)

Ocular Hypertension | Open Angle Glaucoma

Spain, Germany, United States, Estonia
Sylentis, S.A.

Completed

HELIX, a Double-masked Study of SYL1001 in Patients With Moderate to Severe Dry Eye Disease (DED)

Dry Eye Disease

Spain, Portugal, Italy, Estonia, Germany, Slovakia
Sylentis, S.A.

Completed

Dose-finding Study to Assess the Safety and Effect of SYL1001 in Patients With Ocular Pain

Ocular Pain | Dry Eye Syndrome

Spain, Estonia
Sylentis, S.A.

Completed

Pilot Study to Evaluate SYL1001 Safety and Effect in Patients With Ocular Pain

Ocular Pain | Dry Eye Syndrome

Spain
Valentis

Completed

Trial of VLTS-934 in Subjects With Intermittent Claudication Secondary to Peripheral Arterial Disease

Peripheral Vascular Disease

United States
Ceric Sàrl
Symetis SA

Completed

Safety and Efficacy Comparison Of Two TAVI Systems in a Prospective Randomized Evaluation II (SCOPE II)

Aortic Valve Stenosis

Germany, France, Spain, United Kingdom, Denmark, Italy
Symetis SA

Completed

ACURATE Neo™ TA Delivery System in Patient With Severe Aortic Stenosis

Aortic Stenosis

Germany
Symetis SA

Completed

ACURATE Neo™ Aortic Bioprosthesis for Implantation Using the ACURATE TA™ LP Transapical Delivery System in Patients With Severe Aortic Stenosis (TALP-FIM)

Aortic Stenosis

Germany
Symetis SA

Completed

ACURATE TA™ Valve Implantation: SAVI Registry (Surveillance Plan #2011-02) (TA-SAVI)

Symptomatic Aortic Stenosis

Germany, Italy, Argentina, Switzerland
M.A. Med Alliance S.A.

Recruiting

SELUTION 4 De Novo Small Vessel IDE Trial

Coronary Artery Disease

United States
M.A. Med Alliance S.A.

Recruiting

The SELUTION DeNovo Study

Coronary Artery Disease

France, Czechia, United Kingdom, Germany, Italy, Switzerland, Austria, Finland, Poland
M.A. Med Alliance S.A.

Active, not recruiting

SAVE Trial - Use of the Selution Sirolimus Eluting Balloon for Dysfunctional AV accEss Treatment Indications (SAVE)

AV Fistula

Greece, Singapore
M.A. Med Alliance S.A.

Active, not recruiting

SUCCESS (SelUtion, Safety, effiCaCy, hEalth economicS and promS) PTA Study (SUCCESS PTA)

Peripheral Artery Disease

Germany
Valentis

Completed

Trial of VLTS-589 in Subjects With Intermittent Claudication

Intermittent Claudication | Peripheral Vascular Disease

United States
M.A. Med Alliance S.A.

Completed

First-in-human Evaluation of the SELUTION DCB, a Novel Sirolimus Coated Balloon in Peripheral Arteries

Patients With Peripheral Artery Disease in the SFA or PA

Germany
Symetis SA

Completed

ACURATE™ Transapical Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis (2010-01) (TA-PILOT)

Aortic Symptomatic Stenosis

Germany
Symetis SA

Terminated

CHANGE Neo™ TA Registry With ACURATE Neo™ Aortic Bioprosthesis and ACURATE Neo™ TA Transapical Delivery System

Aortic Stenosis

Germany
Symetis SA

Completed

ACURATE TA™ Valve Implantation Registry: SAVI 2 (TA-SAVI2)

Aortic Stenosis

Germany, Austria, Italy, Switzerland
Symetis SA

Completed

ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis (2011-03) (2011-03)

Aortic Stenosis Symptomatic

Germany, Brazil
Symetis SA

Completed

ACURATE Neo™ AS Aortic Bioprosthesis for Implantation Using the ACURATE neoTM AS TF Transfemoral Delivery System in Patients With Severe Aortic Stenosis

Aortic Stenosis

Germany, Denmark, Switzerland
Symetis SA

Completed

PRospective Observation of Aortic reGuRgitation aftEr TAVI and progreSS Over Time: PROGRESS PVL Registry (PROGRESS)

Aortic Stenosis

Germany, Canada, Italy, United Kingdom
Symetis SA

Completed

ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis:CE-approval Cohort

Symptomatic Aortic Stenosis

Germany, Japan, Brazil
Symetis SA

Completed

Feasibility Trial on ACURATE™ Transapical Implantation in Patients With Severe Symptomatic Aortic Stenosis (2009-01) (TA-FIM)

Aortic Stenosis Symptomatic

Germany
Symetis SA

Completed

Symetis ACURATE Neo™ Valve Implantation SAVI TF Registry (SAVI TF)

Aortic Stenosis
Ferrer Internacional S.A.
Histocell, S.L.

Recruiting

Safety and Preliminary Efficacy of FAB117-HC in Patients With Acute Traumatic Spinal Cord Injury (SPINE)

Acute Traumatic Spinal Cord Injury

Spain
Cross Research S.A.
Zambon SpA

Completed

Riluzole Orodispersible Film Replicate Bioavailability

Bioequivalence

Switzerland
Zambon SpA
Cross Research S.A.

Completed

Drug Interaction Study of Safinamide and a BCRP Substrate, Diclofenac, Concomitantly Administered to Healthy Volunteers

Healthy

Switzerland
Cross Research S.A.
Zambon SpA

Completed

Safinamide Steady State Interaction With Rosuvastatin

Healthy

Switzerland
Sintetica SA
Cross S.A.

Completed

Chloroprocaine 2% vs Ropivacaine 0.75% in Ultrasound-guided Axillary Nerve Block

Axillary Nerve Block

Switzerland
Tilman S.A.
Bioxtract SA

Completed

Exploratory Non Comparative Study to Evaluate the Efficacy of Highly Bioavailable Curcumin (Flexofytol) in Patients With Knee Osteoarthritis

Knee Osteoarthritis

Belgium
Sintetica SA
Cross S.A.

Completed

Spinal Anaesthesia With Chloroprocaine HCl 1% for Elective Lower Limb Procedures of Short Duration.

Short Duration Lower Limb Surgery Via Spinal Anaesthesia

Italy
Serentis Ltd.

Completed

Phase IIa Safety and Efficacy Study of SRD174 Cream in Patients With AD-associated Pruritus

Pruritus, Atopic Dermatitis

United States
Serentis Ltd.

Completed

Safety and Efficacy of SRD441 Ointment in Patients With Atopic Dermatitis

Atopic Dermatitis

Germany, Bulgaria, Finland
Sintetica SA
Cross S.A.

Completed

Dose-finding Study of Intrathecal Paracetamol Administered Immediately Before Spinal Anaesthesia

Phase 1: Pain Management | Phase 2: Pain Management

Switzerland
Faes Farma, S.A.
Dynamic Science S.L.

Completed

Study to Assess the Safety, Tolerability and Efficacy of Bilastine Ophthalmic Solution 0.6% in Children

Allergic Conjunctivitis

Spain
Faes Farma, S.A.
Dynamic Science S.L.

Terminated

Efficacy and Safety of Hemorrane Plus Versus Hemorrane and Versus Placebo in Patients With Uncomplicated Haemorrhoids

Haemorrhoids Without Complication

Spain
Team Foods Colombia S.A.
Biopolis S.L.

Unknown

Study to Evaluate the Effect of a Vegetal Oil on Cognitive Impairment

Alzheimer Disease | Cognitive Impairments

Spain
Chang Gung Memorial Hospital
Scientis Pharma SA

Recruiting

Efficacy and Safety of Topical Cysteamine for Postinflammatory Hyperpigmentation

Hyperpigmentation; Postinflammatory

Taiwan
Alentis Therapeutics AG

Recruiting

Rescue of Nephrons With ALE.F02 (RENAL-F02) (RENAL-F02)

Glomerulonephritis Rapidly Progressive

Czechia, Spain, Germany, Denmark, Italy, United Kingdom, France, Switzerland, Sweden, Turkey
Alentis Therapeutics AG

Recruiting

A Clinical Trial of ALE.F02 in Patients With Advanced Liver Fibrosis and/or With Mild Cirrhosis (FEGATO-01)

Liver Cirrhosis | Advanced Liver Fibrosis

Germany, Romania, Slovakia
Sintetica SA
Cross Research S.A.

Terminated

Chloroprocaine 3% - Epidural Anesthesia in Unplanned Caesarean Section

Unplanned Caesarean Section

Belgium
Sintetica SA
Cross Research S.A.

Completed

Intrathecal Paracetamol Before Spinal Anaesthesia With Chloroprocaine HCl 1% for Short Knee Procedures

Pain, Postoperative

Switzerland

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