Clinical Trials Sponsored by Wellcome Trust

Total 6213 results

Solent NHS Trust

Unknown

Parent-based Intervention for Language Delayed 2 to 3 Year Olds

Speech and Language Therapy
Solent NHS Trust

Completed

Respiratory Monitoring of Intrathecal Baclofen- a Feasibility Study

Multiple Sclerosis | Cerebral Palsy | Respiratory System | Intrathecal Baclofen

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
King's College Hospital NHS Trust; Portsmouth Hospitals NHS Trust; North Bristol... and other collaborators

Recruiting

Day-case Endourology; Patient Experience

Bladder Cancer | Bladder Outflow Obstruction

United Kingdom
P1vital Products Limited
Wellcome Trust (Funder); Uppsala University (Department of Psychology); Intensive... and other collaborators

Completed

A Brief Cognitive Task Intervention for NHS Staff Affected by COVID-19 Trauma (GAINS-2 Study) (GAINS-2)

Intrusive Memories of Traumatic Event(s)

United Kingdom
University of Oxford
Kinshasa School of Public Health; Wellcome Sanger Institute

Completed

Monitoring Pregnant Women for Antimalarial Drug Resistance (MIRANDA)

Malaria

Congo, The Democratic Republic of the
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome; Miles

Completed

Randomized, Double-Blind, Placebo-Controlled Trial of Nimodipine for the Neurological Manifestations of HIV-1

HIV Infections | AIDS Dementia Complex

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome; Upjohn

Completed

A Phase I, Dose-Escalating Safety and Tolerance Study of sCD4-PE40 in HIV-Infected Persons

HIV Infections

United States
University of California, Berkeley
University of British Columbia; University College, London; Wellcome Trust; Salk... and other collaborators

Not yet recruiting

Healthy Lifestyles for Bipolar Disorder (HL)

Time Restricted Eating | Diet, Mediterranean

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome; Upjohn

Completed

A Phase I Concentration-Controlled Trial to Assess the Safety, Tolerance, Pharmacokinetics and Development of Decreased HIV-1 Susceptibility to the Combination of Atevirdine Mesylate (U-87201E), Zidovudine (AZT), and Didanosine (ddI)

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome; Upjohn

Completed

A Phase I Concentration-Targeted Multidose Study of Atevirdine Mesylate ( U-87201E ), AZT, and ddI or ddC

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Abbott; Glaxo Wellcome

Terminated

The Safety and Effectiveness of Hyperimmune Anti-HIV Intravenous Immunoglobulin (HVIG) Plus Zidovudine in HIV-Infected Infants

HIV Infections
Papworth Hospital NHS Foundation Trust
Hinchingbrooke Healthcare NHS Trust

Completed

PAIR Study-PAP And IOP Relationship: Study 2 (PAIR2)

Primary Open-angle Glaucoma | Obstructive Sleep Apnoea

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Ben Williams Trust

Unknown

Families' Experiences of Paediatric ICC Diagnosis (FEPICCD)

Inherited Cardiac Conditions
London School of Hygiene and Tropical Medicine
Liverpool School of Tropical Medicine; Kamuzu University of Health Sciences; Malawi-Liverpool-Wellcome...

Completed

Computer Aided Screening for Tuberculosis in Low Resource Environments (CASTLE)

HIV Infections | Tuberculosis Infection

Malawi
University of Alabama at Birmingham
National Cancer Institute (NCI); Glaxo Wellcome

Completed

Eniluracil and Surgery in Treating Patients With Primary or Metastatic Colorectal Cancer

Colorectal Cancer
University of Pennsylvania
Burroughs Wellcome; Bayer Droegemueller Award in Clinical Research

Completed

Direct Measurements of Cervical Remodeling for Predicting Preterm Birth

Preterm Birth

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome; Upjohn

Completed

A Pilot Study of Oral Clindamycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDS

HIV Infections | Toxoplasmosis, Cerebral

United States
Fred Hutchinson Cancer Center
National Institutes of Health (NIH); Burroughs Wellcome

Completed

Long-Term Oral Acyclovir Usage to Prevent Herpes Zoster Virus Infection After Bone Marrow Transplant

VZV Infection After Bone Marrow Transplantation

United States
University of Manchester
Manchester University NHS Foundation Trust; Hull University Teaching Hospitals... and other collaborators

Completed

Saving Babies' Lives Project Impact and Results Evaluation: a Mixed Methodology Study (SPiRE)

Stillbirth

United Kingdom
Papworth Hospital NHS Foundation Trust
LifeArc; Cystic Fibrosis Trust

Recruiting

ANNE Sensor Monitoring in Cystic Fibrosis (ASM in CF)

Cystic Fibrosis

United Kingdom
University Hospital Southampton NHS Foundation...
Solent NHS Trust

Unknown

Paediatric Post Pneumococcal Conjugate Vaccine Nasopharyngeal Carriage Study

Pneumococcal Conjugate Vaccine | S. Pneumoniae

United Kingdom
Papworth Hospital NHS Foundation Trust
Hinchingbrooke Hospital NHS Trust

Terminated

PAIR Study-PAP And IOP Relationship: Study 1 (PAIR)

Primary Open Angle Glaucoma | Obstructive Sleep Apnoea

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Imperial College Healthcare NHS Trust; Royal Cornwall Hospitals Trust

Unknown

Assessment of Olfactory Dysfunction in SARS CoV-2 (COVID-19) Infection (ODYSSI)

Quality of Life | Anosmia | SARS-CoV-2 | COVID19 | Olfactory Disorder | Microsomia | Smell Disorder

United Kingdom
Liverpool University Hospitals NHS Foundation Trust
University Hospital Plymouth NHS Trust; Medway NHS Foundation Trust; Maidstone... and other collaborators

Completed

CPET in Colorectal Surgery

Colorectal Cancer | Surgery

United Kingdom
Norwegian University of Science and Technology
Vestre Viken Hospital Trust; University of Oslo; University of Bergen; University... and other collaborators

Enrolling by invitation

The Norwegian Trial of Physical Exercise After Myocardial Infarction (NorEx)

Myocardial Infarction

Norway
University Hospital Southampton NHS Foundation...
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust; Portsmouth... and other collaborators

Unknown

The Wessex Fit-4-Cancer Surgery Trial (WesFit)

Cancer

United Kingdom
University of California, San Diego
Stanford University; Cornell University; Wellcome Leap Organization

Recruiting

Individualized Neuromodulation for Anhedonic Depression

Anhedonia | MDD

United States
London School of Hygiene and Tropical Medicine
King's College London; Wellcome Trust; University of Cambridge; National Nutrition... and other collaborators

Completed

A Novel Nano-iron Supplement to Safely Combat Iron Deficiency and Anaemia in Young Children: a Doubleblind Randomised Controlled Trial (IHAT-Gut)

Iron Deficiency, Anaemia in Children

Gambia
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Nottingham University Hospitals NHS Trust; Barts & The London NHS Trust and other collaborators

Recruiting

The BARCODE 2 Study - The Use of Genetic Profiling to Guide Prostate Cancer Treatment (BARCODE2)

Hormone Refractory Prostate Cancer

United Kingdom
University of Nottingham
Northern Care Alliance NHS Foundation Trust; Cambridge University Hospitals... and other collaborators

Recruiting

Pseudo-obstruction Assessment With MRI (POM)

Chronic Intestinal Pseudo-Obstruction

United Kingdom
University of Surrey
The Leeds Teaching Hospitals NHS Trust; University Hospital Birmingham NHS... and other collaborators

Recruiting

The National Transition Evaluation Study (NTES)

Young People With All Long-term Health Conditions

United Kingdom
Nottingham University Hospitals NHS Trust
Northern Care Alliance NHS Foundation Trust; Barts & The London NHS Trust; University... and other collaborators

Not yet recruiting

Neurological Recovery Following NOS-SACD

Paresthesia | Neurologic Symptoms | B12 Deficiency Vitamin | Nitrous Oxide Abuse | Subacute Combined Cord Degeneration
The Christie NHS Foundation Trust
Manchester University NHS Foundation Trust

Completed

PDAC Peripheral and Portal Vein Sampling

Pancreatic Adenocarcinoma

United Kingdom
Oslo University Hospital
Vestre Viken Hospital Trust; Ostfold Hospital Trust

Active, not recruiting

Intramedullary Nailing Versus Plate Fixation of Ankle Fractures. A Prospective, Randomized Controlled Trial.

Ankle Fractures

Norway
University of Southampton
Salisbury NHS Foundation Trust; Solent NHS Trust

Completed

Optimising Community Resources and Support to Enhance Living With Parkinson's Disease (OPTIM-PARKII)

Parkinson Disease

United Kingdom, Spain
Barts & The London NHS Trust
King's College Hospital NHS Trust

Withdrawn

MyIBD Care - Feasibility Study

Inflammatory Bowel Diseases
Guy's and St Thomas' NHS Foundation Trust
Velindre NHS Trust

Completed

18F-FDG-PET Guided Dose-Painting With Intensity Modulated Radiotherapy in Oropharyngeal Tumours (FiGaRO)

Oropharyngeal Cancer

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust
Insulin Dependant Diabetes Trust

Completed

Retinal Laser by Multi-spot Photocoagulator and Driving Eligibility

Proliferative Diabetic Retinopathy

United Kingdom
Barts & The London NHS Trust
London Ambulance Service NHS Trust

Unknown

Safety and Efficacy of Paramedic Treatment of Regular Supraventricular Tachycardia (Para-SVT)

Supraventricular Tachycardia

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Novartis; Barts & The London NHS Trust; The Christie NHS Foundation Trust; Oxford...

Terminated

Pasireotide Therapy in Patients With Nelson's Syndrome

Nelson Syndrome

United Kingdom
University of Nottingham
Burdett Trust for Nursing; Nottinghamshire Healthcare NHS Trust; Nottingham City... and other collaborators

Completed

Promoting Wellbeing for Women With Depression: A Pragmatic Randomised Controlled Trial (RCT) of an Exercise Programme

Depression

United Kingdom
The Griffin Institute
Medtronic; Wellcome/EPSRC for Interventional and Surgical Sciences (WEISS)

Recruiting

Video Analysis of Errors and Technical Performance Within Minimally Invasive Surgery Short Title: Video Analysis in Minimally Invasive Surgery (VAMIS) (VAMIS)

Rectal Cancer | Prostate Cancer

United Kingdom
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.; Glaxo Wellcome

Completed

A Phase I/II Trial of Vaccine Therapy of HIV-1 Infected Individuals With 50-500 CD4 Cells/mm3

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Jacobus Pharmaceutical; Glaxo Wellcome

Completed

A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Royal Marsden NHS Foundation Trust
Cambridge University Hospitals NHS Foundation Trust; University Hospital Plymouth...

Unknown

Tissue Collection for Biomarkers Determining Resistance to Ibrutinib (CLARITY)

Mantle Cell Lymphoma | Chronic Lymphocytic Leukaemia

United Kingdom
University of Oxford
King's College Hospital NHS Trust; Nottingham University Hospitals NHS Trust; Guy's and St Thomas' NHS Foundation Trust and other collaborators

Enrolling by invitation

Echocardiography: Value and Accuracy at REst and STress (EVAREST)

Coronary Artery Disease | Angina Pectoris | Ischaemic Heart Disease
King's College London
King's College Hospital NHS Trust; Guy's and St Thomas' NHS Foundation Trust; Imperial College Healthcare NHS Trust and other collaborators

Completed

Mental Wellbeing and Quality of Life in Prostate Cancer (MIND-P)

Prostate Cancer

United Kingdom
King's College Hospital NHS Trust
Barts & The London NHS Trust

Recruiting

Effect of Premedicant Oral Paracetamol on Gastric Volume and pH

Fasting

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College Healthcare NHS Trust

Completed

Primary Radiotherapy And DIEP flAp Reconstruction Trial (PRADA)

Breast Cancer

United Kingdom
Vestre Viken Hospital Trust
Oslo University Hospital; Ostfold Hospital Trust

Completed

Ziptight or Tricortical Screw Fixation of Acute Tibiofibular Syndesmotic Injury (S16)

Ankle Fractures

Norway

Clinical Trials Sponsored by Wellcome Trust

Sponsors and Collaborators

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Drug Interventions

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CROs in Belarus

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