Search clinical trials for: AHR inhibitor

Total 68408 results

Johns Hopkins University
United States Agency for International Development (USAID)

Not yet recruiting

Shortened Regimen for Drug-susceptible TB in Children (SMILE-TB)

Tuberculosis | Tuberculosis, Pulmonary | Mycobacterium Tuberculosis | Tuberculosis, Lymph Node

Uganda, South Africa, Mozambique, Indonesia, Zambia
Pfizer

Recruiting

First-line Palbociclib and Endocrine Therapy for Patients With HR+/HER2- Advanced Breast Cancer in the Real-world Setting. (PERFORM)

Breast Neoplasms

Austria, Germany
Philogen S.p.A.

Recruiting

A Study Comparing the Efficacy of L19TNF+Doxorubicin vs Doxorubicin Alone as First-line Therapy in Patients With Advanced or Metastatic Soft Tissue Sarcoma (FIBROSARC)

Soft Tissue Sarcoma

Spain, Germany, France, Italy, Poland
QuantumLeap Healthcare Collaborative
M.D. Anderson Cancer Center; University of Colorado, Denver; University of Pennsylvania and other collaborators

Recruiting

I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients (I-SPY_COVID)

COVID-19

United States
Harry H Yoon
Mayo Clinic; Merck Sharp & Dohme LLC

Recruiting

Novel SEQUEnced Immunotherapy With Anti-angiogenesis and Chemotherapy in Advanced gastroesophageaL Adenocarcinoma (SEQUEL)

Adenocarcinoma | Gastric Cancer | GastroEsophageal Cancer

United States
Veronika Bachanova
Bristol-Myers Squibb; Incyte Corporation

Recruiting

Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma

Hodgkin Lymphoma

United States
Kari Wisinski
Novartis; University of Wisconsin, Madison; Big Ten Cancer Research Consortium

Recruiting

Ribociclib and Bicalutamide in AR+ TNBC

Triple Negative Breast Cancer

United States
Bayer

Active, not recruiting

A Study to Learn How Safe the Study Drug BAY 2416964 (AhR Inhibitor) in Combination With the Treatment Pembrolizumab is, How This Combination Affects the Body, the Maximum Amount That Can be Given, How it Moves Into, Through and Out of the Body and Its Action Against Advanced Solid Cancers in Adults

Advanced Solid Tumors

United States, Singapore, Italy, United Kingdom
University of Wisconsin, Madison
Agency for Healthcare Research and Quality (AHRQ)

Enrolling by invitation

FQ Restriction for the Prevention of CDI (FIRST)

Clostridium Difficile Infection | Clostridium Difficile | C Difficile Colitis

United States
Ikena Oncology
Bristol-Myers Squibb

Withdrawn

Oral AHR Antagonist in Combination With Nivolumab in Patients With PD-1 Resistant Metastatic or Recurrent Head and Neck Cancer

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Head Cancer | Neck Cancer | Head Cancer Neck | Neck Carcinoma

United States
Ikena Oncology
Bristol-Myers Squibb

Completed

A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma

Neoplasms | Neoplasm Metastasis | Solid Tumor | Metastatic Cancer | Bladder Cancer | Advanced Solid Tumor | Advanced Cancer | Urothelial Carcinoma Bladder | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Solid Tumor, Adult | Bladder Disease | Solid Carcinoma | Neoplasm Malignant | Neoplasm, Bladder | Locally Advanced... and other conditions

United States
Bayer

Completed

A First-in-Humans Dose Finding Study for an Aryl Hydrocarbon Receptor Inhibitor (AhRi) in Patients With Advanced Cancer

Advanced Solid Tumors

Spain, United States, United Kingdom, Germany, Canada
Jeffrey Clarke
Merck Sharp & Dohme LLC; Grid Therapeutics

Suspended

Study of GT103 in Combination With Pembrolizumab in Refractory, Metastatic Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer | Metastatic NSCLC | Recurrent Non Small Cell Lung Cancer

United States
Salma Sabbour
Bristol-Myers Squibb; Rutgers Cancer Institute of New Jersey; BeyondSpring Pharmaceuticals...

Active, not recruiting

A Phase I/II Study of Nivolumab, Ipilimumab and Plinabulin in Patients With Recurrent Small Cell Lung Cancer

Lung Cancer | SCLC

United States
Ain Shams University
Ahram Canadian University

Completed

The Impact of Sitagliptin as an Add on Therapy With Closed Loop Control in Adolescents With Diabetic Nephropathy

Type 1 Diabetic Nephropathy

Egypt
Indiana University
Agency for Healthcare Research and Quality (AHRQ)

Completed

Short Stay Unit vs Hospitalization in Acute Heart Failure (SSU-AHF)

Acute Heart Failure

United States
Daiichi Sankyo, Inc.

Completed

Edoxaban Treatment in Routine Clinical Practice for Patients With Non Valvular Atrial Fibrillation (ETNA-AF-EU)

Atrial Fibrillation

Spain, Italy, Germany, Switzerland, Portugal, Belgium, Austria, Ireland, Netherlands, United Kingdom
Johns Hopkins University
Agency for Healthcare Research and Quality (AHRQ)

Completed

Treating Parents to Reduce NICU Transmission of Staphylococcus Aureus Trial (TREAT PARENTS)

Staph Aureus Colonization | Staph Aureus Infection

United States
UCB Pharma SA

Completed

Noninterventional Examination of Subcutaneous (sc) Tumor Necrosis Factor (TNF) Inhibitors (NexT)

Rheumatoid Arthritis

Germany
Beni-Suef University
Ahram Canadian University

Unknown

The Effect of Metformin on Breast Cancer Patients

Breast Cancer

Egypt
NorthShore University HealthSystem
Agency for Healthcare Research and Quality (AHRQ)

Completed

Detection, Education, Research and Decolonization Without Isolation in Long-term Care Facilities (DERAIL_MRSA)

Methicillin Resistant Staphylococcus Aureus

United States
Paolo Goffredo

Unknown

Antibiotic Irrigations for Intra-Abdominal Drains (AID)

Abdominal Abscess

United States
Northwestern University
University of Chicago; Purdue University; Agency for Healthcare Research and... and other collaborators

Completed

Healthy Hearts in the Heartland (H3)

Cardiovascular Diseases

United States
NYU Langone Health
Agency for Healthcare Research and Quality (AHRQ)

Completed

Using Practice Facilitation in Primary Care Settings to Reduce Risk Factors for Cardiovascular Disease

Cardiovascular Disease | High Blood Pressure

United States
University of Colorado, Denver
Agency for Healthcare Research and Quality (AHRQ)

Completed

Medication Management and Culture of Safety (MM)

Cardiovascular Disease

United States
AstraZeneca

Completed

Efficacy and Safety of Dapagliflozin and Dapagliflozin Plus Saxagliptin in Combination With Metformin in Type 2 Diabetes Patients Compared With Sulphonylurea

Type 2 Diabetes Mellitus | Inadequate Glycaemic Control

Germany, Slovakia, Czechia, Hungary, Poland
Postgraduate Institute of Medical Education and...

Completed

Trial of Aggressive Hydration Versus Rectal Indomethacin for Prevention of Post-ERCP Pancreatitis (AHRI-PEP)

Post-ERCP Acute Pancreatitis

India
Harvard Pilgrim Health Care
Centers for Disease Control and Prevention; University of California, Irvine; Agency for Healthcare Research and Quality (AHRQ) and other collaborators

Completed

Cluster Randomized Trial of Hospitals to Assess Impact of Targeted Versus Universal Strategies to Reduce Methicillin-resistant Staphylococcus Aureus (MRSA) in Intensive Care Units (ICUs) (REDUCE-MRSA)

Methicillin-resistant Staphylococcus Aureus

United States
Kaiser Permanente
Johns Hopkins University; Agency for Healthcare Research and Quality (AHRQ); Kaiser...

Completed

Promoting Adherence to Improve Effectiveness of Cardiovascular Disease Therapies (PATIENT)

Cardiovascular Disease | Diabetes Mellitus

United States
Indiana University
Agency for Healthcare Research and Quality (AHRQ)

Terminated

Comparative Research of Alzheimer's Disease Drugs (COMET-AD)

Dementia | Alzheimer's Disease

United States
GlaxoSmithKline

Completed

"REDUCE" - A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased Risk (REDUCE)

Neoplasms, Prostate

United States, Australia, France, Germany, Spain, Bulgaria, Estonia, Italy, Poland, Netherlands, Belgium, United Kingdom, Canada, Denmark, Ukraine, Finland, Latvia, Russian Federation, Greece, Slovenia, Brazil, Mexico, Slovakia, Japan, Puerto... and more
M.D. Anderson Cancer Center
Agency for Healthcare Research and Quality (AHRQ)

Completed

Diabetic Treatment Adherence

Endocrine System Diseases

United States
Novartis Pharmaceuticals

Terminated

This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart Failure (PARADIGM-HF)

Heart Failure With Reduced Ejection Fraction

China, Germany, United States, Colombia, Korea, Republic of, Romania, South Africa, Canada, Belgium, Estonia, Hungary, Italy, Russian Federation, Taiwan, Turkey, United Kingdom, Spain, France, Netherlands, Hong Kong, Bulgaria, Israel and more
Novartis Pharmaceuticals

Completed

Efficacy and Safety Study of Methylphenidate Hydrochloride Extended Release in Adults With Childhood-onset Attention Deficit/Hyperactivity Disorder (ADHD)

Attention Deficit/Hyperactivity Disorder

United States, Germany, Singapore, Colombia, Sweden, Belgium, South Africa, Denmark, Norway
Charite University, Berlin, Germany

Completed

Effects of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) on RAdiographic Damage in Ankylosing Spondylitis (ENRADAS)

Ankylosing Spondylitis

Germany
Eli Lilly and Company

Completed

A Long Term Study of a Medication for Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)

Attention Deficit Hyperactivity Disorder

Spain, France, Austria, Germany, Belgium, Finland, Italy, Netherlands, Portugal, Sweden, Switzerland, United Kingdom
Janssen-Cilag International NV

Completed

A Study to Evaluate Effectiveness and Safety of Prolonged Release OROS Methylphenidate in Adults With Attention Deficit Hyperactivity Disorder

Attention Deficit/ Hyperactivity Disorder

France, Belgium, Germany, Spain, Switzerland, Denmark, Finland, Netherlands, Norway, Sweden, United Kingdom
Janssen-Cilag International NV

Completed

Open Label, Multicentre Extension Study of Protocol 42603ATT3002 to Evaluate Safety of Prolonged Release OROS Methlyphenidate in Adults With Attention Deficit Hyperactivity Disorder (ADHD)

Attention Deficit Disorder With Hyperactivity

France, Germany, Spain, Switzerland, Netherlands, Portugal, Norway
Agency for Healthcare Research and Quality (AHRQ)

Completed

Management of Vaginal Complaints: A Pilot Study Within a Practice-Based Research Network (VCAT)

Vaginitis

United States
Duke University
Pfizer; Agency for Healthcare Research and Quality (AHRQ)

Completed

Study of an Intervention to Improve Use of Life-saving Medications for Heart Disease (PILOT-EBM)

Cardiovascular Disease

United States
Mego Afek Ltd.

Completed

Safety and Efficacy Study of a New Intermittent Pneumatic Compression Device to Treat Patients With Peripheral Arterial Disease (PAD) Stage II

Peripheral Arterial Disease

Israel, Germany
Nycomed

Completed

Efficacy of Pantoprazole in Patients Older Than 12 Years With Reflux Associated Sleep Disorders (PULS) (PULS)

Erosive Gastroesophageal Reflux Disease | Non-Erosive Reflux Disease

Germany
Nycomed

Completed

Efficacy of Pantoprazole in Patients Older Than 12 Years Who Have Symptoms of Non-Erosive Reflux Disease (NERD) or Erosive Gastroesophageal Reflux Disease (eGERD) (PANTHER)

Gastroesophageal Reflux Disease

Germany
Nycomed

Completed

Pantoprazole 20/40 mg in the Treatment of Symptomatic Reflux Disease With Focus on Sleep Disorders (PANDA)

Gastroesophageal Reflux Disease | Sleep Disorders | Non-Erosive Reflux Disease

Germany
Nycomed

Completed

Efficacy of Pantoprazole 20/40 mg Once Daily (od) in Patients Older Than 12 Years Who Have Gastrointestinal Symptoms of Reflux Disease (PARADE)

Gastroesophageal Reflux Disease

Germany
Geisinger Clinic
Agency for Healthcare Research and Quality (AHRQ)

Completed

Improving Aspirin Use Among Adults at Risk for Cardiovascular Disease (CVD)

Cardiovascular Disease

United States
Zhejiang Cancer Hospital

Not yet recruiting

Phase II Study of Liposomal Irinotecan for Advanced Refractory Gastric Cancer

Gastric Cancer

China
Wuhan Union Hospital, China

Recruiting

Efficacy and Safety of Ganciclovir Capsules in the Treatment of Refractory Moderate-to-severe Allergic Rhinitis

Rhinitis, Allergic

China
Beijing Tongren Hospital
The First Affiliated Hospital with Nanjing Medical University

Not yet recruiting

Efficacy and Safety of Sugammadex in Thoracoscopy Thymectomy for Chinese Adults With Myasthenia Gravis

Reversal of Neuromuscular Blockade

China
First Affiliated Hospital of Zhejiang University
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.

Recruiting

Mitoxantrone Hydrochloride Liposome Injection, Cytarabine Combined With Venetoclax in the Treatment of R/R AML

Myeloid Malignancy | Relapsed/Refractory Acute Myeloid Leukaemia

China

Search clinical trials for: AHR inhibitor

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