Search clinical trials for: Adult Macular Degeneration

Total 29132 results

Regeneron Pharmaceuticals

Not yet recruiting

An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting (SPECTRUM-US)

Visual Impairment | Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (nAMD) | Wet Age-related Macular Degeneration (AMD)
AbbVie

Recruiting

Observational Study of Adult Participants With Diabetic Macular Edema and Suboptimal Response to Anti-Vascular Endothelial Growth Factor Treated With Dexamethasone Intravitreal Implant

Diabetic Macular Edema

Greece, Portugal, Belgium, United Kingdom, Italy, Israel, China, Germany
The University of Texas Medical Branch, Galveston
National Institute on Aging (NIA)

Recruiting

Comparative Effectiveness of Initial OAB Treatment Options Among Older Women at High Risk of Falls

Urinary Bladder, Overactive | Urinary Incontinence | Accidental Falls

United States
The University of Hong Kong
The Hong Kong Polytechnic University; The Hong Kong Society for the Blind

Recruiting

Expressive Arts-based Intervention for Adults With Age-related Visual Impairment

Age-Related Macular Degeneration

Hong Kong
Quan Dong Nguyen
Oculis; Global Ophthalmic Research Center (GORC)

Recruiting

Multicenter Study on the Efficacy and Safety of OCS-01 in Subjects With Uveitis Related and Post Surgical Macular Edema (LEOPARD)

Uveitis Related Cystoid Macular Edema | Cystoid Macular Edema, Postoperative

United States
The Foundation for Orthopaedics and Regenerative...

Recruiting

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Eye Diseases

Glaucoma | Eye Diseases | Macular Degeneration | Diabetic Retinopathy | Retinitis Pigmentosa | Optic Atrophy | Traumatic Optic Neuropathy

Antigua and Barbuda, Argentina, Mexico
Paul A Knepper, MD PhD

Recruiting

A Study to Evaluate the Safety and Efficacy of RQC for AMD

Age-related Macular Degeneration

United States
Centre Hospitalier Universitaire Dijon

Recruiting

Medico Economic Evaluation of Fluocinolone Acetonide Implant Versus Dexametheasone Implant in Resistant Diabetic Macular Oedema (EMMA)

Diabetic Macular Edema

France
University of Waterloo
The Hong Kong Polytechnic University

Recruiting

Learning Study: Improving Vision in Adults With Macular Degeneration

Macular Degeneration

Hong Kong, Canada
Hospices Civils de Lyon

Recruiting

Pilot and Phase 2 Study of the Efficacy of a Treatment Protocol With Dexamethasone Implant Loading Dose in Patients With Diabetic Macular Edema (LOADEX) (LOADEX)

Diabetic Macular Edema

France
Astellas Institute for Regenerative Medicine

Recruiting

A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration

Age-Related Macular Degeneration

United States
Millennium Pharmaceuticals, Inc.

Terminated

Study of Dexamethasone Plus IXAZOMIB (MLN9708) or Physicians Choice of Treatment in Relapsed or Refractory Systemic Light Chain (AL) Amyloidosis

Relapsed or Refractory Systemic Light Chain Amyloidosis

United States, Canada, Spain, Israel, France, Australia, Denmark, Germany, Korea, Republic of, Greece, Netherlands, Brazil, Czechia, Italy, United Kingdom
Texas Retina Associates
The Emmes Company, LLC

Completed

One Year Trial Evaluating Safety of Ozurdex With Eylea (COED)

Diabetic Macular Edema

United States
Oxular Limited

Active, not recruiting

Suprachoroidal Sustained-Release OXU-001 Compared to Intravitreal Ozurdex® in the Treatment of Diabetic Macular Edema (OXEYE)

Diabetic Macular Edema

United States, Puerto Rico
National University of Singapore
National University Hospital, Singapore; Ministry of Education, Singapore

Active, not recruiting

Impact of Regular Consumption of Grapes on Eye Health in Singapore Older Adults

Age-related Macular Degeneration | Eye Health

Singapore
Assiut University

Active, not recruiting

Functional and Anatomical Outcomes of Dexamethasone Intra-vitreal Implant in Patients With Resistant Macular Edema Secondary to Retinal Vein Occlusion After Intravitreal Anti-VEGF Injection

Macular Edema | Retinal Vein Occlusion

Egypt
Alvotech Swiss AG
Iqvia Pty Ltd

Completed

A Study to Investigate the PK, Safety, and Tolerability Between AVT05, US and EU Simponi® in Healthy Adult Participants

Healthy Adult Subjects

New Zealand, United Kingdom
Novartis Pharmaceuticals

Completed

Study of Brolucizumab in Adult Patients With Suboptimal Anatomically Controlled Neovascular Age-related Macular Degeneration (SWIFT)

Neovascular Age-Related Macular Degeneration

France
AbbVie

Completed

A Study to Evaluate an Updated Dexamethasone Intravitreal (Into the Eye) Applicator in Adult Participants With Macular Edema Due to Diseases of the Retina

Macular Edema

United States
Novartis Pharmaceuticals

Completed

A Study to Assess the Effects of Brolucizumab in Adult Patients With Neovascular Age Related Macular Degeneration (OCTOPUS)

Neovascular Age Related Macular Degeneration

France
Mayo Clinic
National Eye Institute (NEI)

Completed

Stem Cell Models of Best Disease and Other Retinal Degenerative Diseases.

Retinal Disease | Best Vitelliform Macular Dystrophy | Bestrophinopathy | Adult Onset Vitelliform Macular Dystrophy | Autosomal Dominant Vitreoretinalchoroidopathy

United States
University of Waterloo
The Hong Kong Polytechnic University

Completed

Improving Vision in Adults With Macular Degeneration

Macular Degeneration

Canada, Hong Kong
Smilebiotek Zhuhai Limited

Completed

QA102 Phase 1 Study in Healthy Young and Older Adult Subjects

Age-related Macular Degeneration

United States
Sucampo Pharma Americas, LLC
Sucampo Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Ocular Blood Flow Effects of Unoprostone Isopropyl in Adults With Dry Age-related Macular Degeneration

Dry Age-related Macular Degeneration

Austria
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

Sorafenib, Epirubicin, Ifosfamide, and Radiation Therapy Followed By Surgery in Treating Patients With High-Risk Stage II or Stage III Soft Tissue Sarcoma

Sarcoma

United States
GlaxoSmithKline

Completed

To Evaluate the Pharmacodynamics, Safety, and Pharmacokinetics of Pazopanib Drops in Adult Subjects With Neovascular AMD

Macular Degeneration

Italy, United States, Belgium, Australia
GlaxoSmithKline

Completed

Clinical Study to Investigate Safety and Efficacy of GSK933776 in Adult Patients With Geographic Atrophy Secondary to Age-related Macular Degeneration

Atrophy, Geographic

United States, Canada
Pfizer

Terminated

A Phase 2, Multi-Center Study To Compare The Efficacy And Safety Of A Chemokine CCR2/5 Receptor Antagonist With Ranibizumab In Adults With Diabetic Macular Edema

Macular Edema, Diabetic

United States, Israel, Germany, Hungary, Bulgaria, Czech Republic, Moldova, Republic of, Poland, Romania
Al-Azhar University
Hassan , Hosny , M.D. M.Sc; Samour , Hany M.D. M.Sc; Ismail , Mahmoud M.D. M.Sc; Higazy , Hasan M.D. M.Sc and other collaborators

Unknown

Safety Study of Use of Autologous Bone Marrow Derived Stem Cell in Treatment of Age Related Macular Degeneration

Age Related Macular Degeneration

Egypt
Unity Health Toronto

Completed

Efficacy and Safety Study to Evaluate Two Doses of Oral DMI-5207 in Adult Subjects With Diabetic Macular Edema

Diabetic Macular Edema
GlaxoSmithKline

Completed

A Study To Evaluate The Safety, Tolerability And Pk Of Pazopanib Eye Drops In Healthy Adult And Elderly Subjects.

Macular Degeneration | Age-related Macular Degeneration

United States
Centre Oscar Lambret

Unknown

Sorafenib in Treating Patients With Angiosarcoma That is Locally Advanced, Metastatic, or Unable to Be Removed by Surgery

Sarcoma

France
Eyestem Research Pvt. Ltd.

Not yet recruiting

Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.

Eye Diseases | Age-Related Macular Degeneration | Macular Degeneration | Geographic Atrophy | Retinal Disease
Belite Bio, Inc

Not yet recruiting

A Phase 2/3 Study to Evaluate the Efficacy and Safety of Tinlarebant in Subjects With Stargardt Disease (DRAGON II)

Stargardt Disease 1 | STGD1

United States
University of Wisconsin, Madison

Recruiting

Retinal Fundus Flavoprotein Fluorescence in Age Related Macular Degeneration (FPF in AMD)

Age-Related Macular Degeneration | Geographic Atrophy

United States
Stealth BioTherapeutics Inc.

Not yet recruiting

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD) (ReNEW)

Age-Related Macular Degeneration
Potsawat Surabotsopon

Not yet recruiting

Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF : Double Blinded, Randomized Control Trial (MIS-TLIF)

Surgery | Disc Degeneration | Spinal Stenosis Lumbar | Fusion of Spine | Disc Disease
Universidade Nova de Lisboa
iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM,... and other collaborators

Recruiting

Intermediate Age-related Macular Degeneration - Multimodal Analysis and Longitudinal Study (Imaging4iAMD)

Age-Related Macular Degeneration

Portugal
Medical University of Vienna
University of Zurich; Centre Hospitalier Universitaire Dijon; Fundacion Clinic... and other collaborators

Not yet recruiting

Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression (APENNINES)

Age-Related Macular Degeneration | Geographic Atrophy
LumiThera, Inc.

Recruiting

A Registry Study to Assess Photobiomodulation in Dry Age-Related Macular Degeneration (EUROLIGHT) (EUROLIGHT)

Dry Age-related Macular Degeneration

Norway
Medical University of Vienna
University of Zurich; Centre Hospitalier Universitaire Dijon; Fundacion Clinic... and other collaborators

Not yet recruiting

Personalised Monitoring of Early and Intermediate Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression (SUDETES)

Age-Related Macular Degeneration
National University of Singapore
California Table Grape Commission

Not yet recruiting

Impact of Grape Powder Consumption on Eye Health and Glycemic Status in Singapore Older Adults

Aging | Macula; Degeneration | Advanced Glycation End Products
Universitaire Ziekenhuizen KU Leuven
DORC Dutch Ophthalmic Research Center International BV

Recruiting

Robotic Subretinal tPA Injection Study (RoTIS)

Age-Related Macular Degeneration | Subretinal Hemorrhage

Belgium
Skyline Therapeutics

Recruiting

A Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients With nAMD

Neovascular (Wet) Age-related Macular Degeneration

China, United States
Centre Hospitalier National d'Ophtalmologie des...

Not yet recruiting

Impact of Age-related Macular Degeneration on Daily Living Activitie (AMDAY)

Age-Related Macular Degeneration
IRCCS Multimedica
AbbVie

Recruiting

OCT and OCT-Angiography Biomarkers of Treatment Response to Dexamethasone Implant in Macular Edema Due to Retinal Vascular Diseases - DME and RVO

Diabetic Macular Edema | Retinal Vein Occlusion | Macular Edema Due to Diabetes Mellitus

Italy
University of Rochester

Not yet recruiting

The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration

Age-Related Macular Degeneration | Retinitis Pigmentosa | Retinal Dystrophies | Alcohol Use Disorder | Stargardt Disease

United States
Rehab Azzam

Not yet recruiting

Outcomes After Vitrectomy in Eyes With Tractional Diabetic Macular Edema

Diabetic Macular Edema
Everads Therapy

Recruiting

Everads Injector in Suprachoroidal Administration of TA Suspension, for Treatment of Patients With DME

Diabetic Macular Edema

Israel
Shanghai Eye Disease Prevention and Treatment Center
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Recruiting

Efficacy and Safety of Conbercept for Diabetic Macular Edema Combined With Severe Non-proliferative Diabetic Retinopathy

Diabetic Macular Edema

China

Search clinical trials for: Adult Macular Degeneration

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