Search clinical trials for: Adults, not adequately controlled, pre-dose morning PEF

Total 16195 results

Chiesi Farmaceutici S.p.A.

Completed

Efficacy and Safety of CHF 1535 200/6µg in Not Adequately Controlled Asthmatic Patients

Asthma

Italy
RenJi Hospital

Not yet recruiting

The Effect of Morning vs Evening Aerobic Exercise Training on Cardiac Remodeling and Function Improvement in Patients After ST Elevation Myocardial Infarction

ST-segment Elevation Myocardial Infarction (STEMI)
Alnylam Pharmaceuticals

Recruiting

Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3) (KARDIA-3)

Hypertension | High Cardiovascular Risk

United States
USDA Grand Forks Human Nutrition Research Center

Recruiting

Exercise for Better Bones - Day or Night?

Overweight

United States
Universidad Complutense de Madrid
McGill University

Not yet recruiting

Dexketoprofen Dosage According to Chronotherapy

Pain | Inflammatory Response | Trismus | Tooth, Impacted
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Timing Intervention of Morning Versus Evening Exercise (TIMEX)

Overweight and Obesity

United States
University of Pittsburgh
National Institute on Drug Abuse (NIDA)

Recruiting

Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens (CARRS-P2)

Delayed Sleep Phase Syndrome

United States
Federal University of Minas Gerais

Recruiting

Chronic Effect of Fasting

Overweight and Obesity

Brazil
University of British Columbia
Laval University; Université de Montréal

Recruiting

Determinants of Tooth Movement in Oral Appliance Treatment of OSA. (TACO)

Obstructive Sleep Apnea

Canada
Almirall, S.A.

Active, not recruiting

A Study of Lebrikizumab in Combination With Topical Corticosteroids in Participants Having Atopic Dermatitis (AD) That Are Not Adequately Controlled or Non-eligible for Cyclosporine

Eczema | Dermatitis, Atopic

Austria, Belgium, France, Germany, Netherlands, Poland, Spain, United Kingdom
University of Pittsburgh
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Delayed Sleep Timing in Teens Study

Delayed Sleep Phase

United States
Astellas Pharma China, Inc.

Completed

A Study to Assess Safety and Efficacy of ASP015K in Participants With Rheumatoid Arthritis (RA) Who Had an Inadequate Response or Intolerance to Methotrexate (MTX)

Rheumatoid Arthritis (RA)

China, Korea, Republic of, Taiwan
Alnylam Pharmaceuticals

Active, not recruiting

Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2) (KARDIA-2)

Hypertension

United States, Canada, Latvia, Poland, United Kingdom, Germany, Lithuania, Estonia, Puerto Rico
Mansoura University

Completed

The Association Between Obstructive Sleep Apnea Severity and Red Blood Cells Indices

Obstructive Sleep Apnea

Egypt
Applied Cognition
University of Florida Health

Completed

Applied Cognition Benchmarking Study (BRAIN3)

Healthy

United States
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

To Compare the Efficacy and Safety of INS068 and Insulin Glargine in Subjects With Type 2 Diabetes Mellitus Not Adequately Controlled With Oral Antidiabetic Drugs

Type 2 Diabetes

China
Novartis

Completed

VALORY Study of Valsartan/Hydrochlorizide for Patients Who do Not Respond Adequately to Olmesartan Medoxomil

Hypertension

Switzerland, Germany
Eli Lilly and Company

Available

Named Patient Use Program to Provide Abemaciclib (LY2835219) for the Treatment of Metastatic Breast Cancer

Metastatic Breast Cancer

Australia, Canada, Egypt, India, Italy, Korea, Republic of, Malaysia, Singapore, South Africa, Spain, Switzerland, Taiwan, Thailand, United Kingdom
Hennepin Healthcare Research Institute

Completed

Peak Expiratory Flow Rate for Emergency Department Management of Acute Asthma Exacerbation

Asthma

United States
Ottawa Hospital Research Institute

Completed

Evaluating the Dose Timing (Morning vs Evening) of Endocrine Therapy and Its Effects on Tolerability and Compliance

Breast Cancer

Canada
Rush University Medical Center

Completed

Chronotherapy in Inflammatory Bowel Disease

Inflammatory Bowel Diseases

United States
HK inno.N Corporation

Completed

A Study to Evaluate the Efficacy and Safety of Amlodipine Besylate and Candesartan Cilexetil in Essential Hypertension Patient Who Are Not Adequately Controlled With Candesartan Cilexetil Monotherapy

Essential Hypertension

Korea, Republic of
HK inno.N Corporation

Completed

A Study to Evaluate the Efficacy and Safety of Amlodipine Besylate and Candesartan Cilexetil in Essential Hypertension Patient Who Are Not Adequately Controlled With Amlodipine Besylate Monotherapy

Essential Hypertension

Korea, Republic of
Tasnem Abo-elouon
Assiut University

Completed

Use of the Modified PUQE Score on Admitted Cases of Hyperemesis Gravidarum (HG) to Guide Response to Treatment

Hyperemesis Gravidarum

Egypt
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Trial of INS068 in Patients With Type 2 Diabetes Not Adequately Controlled With One or Two Oral Antidiabetics

Type 2 Diabetes

Australia, China, United States
Ionis Pharmaceuticals, Inc.

Completed

Addition of ISIS 14803 to Therapy With Peginterferon and Ribavirin for Chronic Hepatitis C (HCV) Patients Not Responding Adequately to the Two Drugs

Hepatitis C, Chronic

United States
Janssen Pharmaceutical K.K.

Terminated

A Study of Ustekinumab in Participants With Active Polymyositis and Dermatomyositis Who Have Not Adequately Responded to One or More Standard-of-care Treatments

Dermatomyositis | Polymyositis

Japan
University of Cincinnati
Gilead Sciences; Abbott

Completed

Immune Reconstitution as a Determinant of Adverse Effects to New Antiretroviral Therapy in Persons With Advanced HIV Infection

HIV Infections

United States
Kowa Company, Ltd.

Completed

A Phase III Long Term Study of K-877 Extended Release Tablet

Dyslipidemias

Japan
Sanofi

Completed

A Study to Evaluate the Efficacy and the Safety of Single Pill Combination (SPC) Ezetimibe/Rosuvastatin in Chinese Adult Patients With Primary Hypercholesterolemia Not Adequately Controlled on Statin Therapy (ROZEL)

Hypercholesterolemia

China
Sanofi

Terminated

Efficacy and Safety of Sotagliflozin Versus Placebo in Chinese Patients With Type 2 Diabetes Mellitus Not Adequately Controlled by Metformin With or Without Sulfonylurea

Type 2 Diabetes Mellitus

China
Sanofi

Terminated

Efficacy and Safety of Sotagliflozin Versus Placebo in Chinese Patients With Type 2 Diabetes Mellitus Not Adequately Controlled by Diet and Exercise

Type 2 Diabetes Mellitus

China
Nottingham Trent University
Loughborough University

Completed

Acute Time-Restricted Eating in Young Healthy Males

Obesity Prevention

United Kingdom
Sanofi
Regeneron Pharmaceuticals

Completed

Safety, Tolerability, and Effect of Alirocumab in High Cardiovascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With Conventional Lipid-modifying Therapies (ODYSSEY APPRISE)

Hypercholesterolemia

France, Belgium, Austria, Canada, Czechia, Denmark, Finland, Germany, Greece, Hungary, Poland, Romania, Slovakia, Slovenia, Spain, Switzerland
Organon and Co

Completed

MK-0954A in Japanese Patients With Essential Hypertension Not Adequately Controlled With Losartan (MK-0954A-352)

Hypertension
Amgen

Completed

A Phase 3B, Open-label, Single-arm Study of the Efficacy and Safety of Apremilast, in Subjects With Plaque Psoriasis That is Not Adequately Controlled by Topical Therapy

Plaque Psoriasis

Japan, Germany
Istanbul Medipol University Hospital

Completed

The Effect of Exercises Performed According to Circadian Rhythm in Type 2 Diabetes (Circadian)

Type 2 Diabetes

Turkey
University of Missouri-Columbia

Completed

Lowering Impaired Fasting Glucose Levels With Exercise (LIFE)

Type2 Diabetes

United States
Nottingham Trent University
Loughborough University

Completed

Fasted Evening Exercise: Performance and Compensatory Eating

Obesity

United Kingdom
Boryung Pharmaceutical Co., Ltd

Completed

BR1010 in Patients With Essential Hypertension Patients Who do Not Adequately Respond to Fimasartan/Amlodipine Combination (FINAL)

Essential Hypertension

Korea, Republic of
ResMed

Terminated

Adherence to ASV Therapy in Heart Failure With Preserved Ejection Fraction Feasibility Study (CAT-PEF)

Sleep Apnea | Heart Failure With Normal Ejection Fraction

United States, Germany
European Organisation for Research and Treatment...
NCIC Clinical Trials Group; Stichting Hemato-Oncologie voor Volwassenen Nederland and other collaborators

Completed

Combination Chemotherapy With or Without Rituximab in Treating Patients With Relapsed Non-Hodgkin's Lymphoma

Lymphoma

France, Netherlands, United Kingdom, Australia, Canada, Norway, Poland, Belgium, Italy, New Zealand, Denmark, Egypt, Hungary, Portugal, Slovakia, Slovenia, South Africa, Sweden
Collegium Medicum w Bydgoszczy

Completed

Effectiveness of Treatment of Hypercholesterolemia With Rosuvastatin and Ezetimibe (ROSEZE)

Hypercholesterolemia

Poland
Novartis Pharmaceuticals

Completed

Assess Bronchodilator Effect QVM149 Dosed Either in the Morning or Evening Compared to Placebo in Patients With Asthma (QVM149)

Asthma

Germany, Netherlands, United Kingdom
Aristotle University Of Thessaloniki
Santen Oy

Completed

Preservative-free Tafluprost/Timolol Fixed Combination: Morning vs Evening Dosing (TTFC)

Glaucoma, Open-Angle

Greece
Shengjing Hospital

Completed

Comparison of Morning Operation and Evening Operation on Postoperative Sleep Quality and Pain Under General Anesthesia

Sleep Quality | General Anesthesia | Circadian Rhythm Sleep Disorder | Morning Operation | Evening Operation

China
Pfizer

Completed

Study to Assess Pharmacokinetics, Safety and Tolerability of PF-04965842 in Chinese Healthy Participants

HEALTHY

China
Hospital de Clinicas de Porto Alegre
Federal University of Rio Grande do Sul

Unknown

Evaluation of Evening Versus Morning Levothyroxine Intake in Elderly (MONIALE)

Aging | Interaction Drug Food | Primary Hypothyroidism

Brazil
Julie Pendergast

Completed

Timed Exercise Study

Circadian Timing - Exercise

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Usability Study of the Commercial Auto-injector Device and the New Auto-injector Device (SYDNEY) in Patients With High or Very High CV Risk With Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Hypercholesterolaemia

United States

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