Search clinical trials for: Adverse drug event

Total 260947 results

The First Affiliated Hospital of Xinxiang Medical...

Not yet recruiting

Pharmacovigilance Assessment of Reporting of Cardiovascular Adverse Events With Antineoplastic Agents (PARCA) (PARCA)

Cardiovascular Diseases | Vascular Diseases | Cancer | Cardiac Diseases
Brazilian Clinical Research Institute
Alliança Diagnostic

Not yet recruiting

Anti-inflammatory and Anti-thrombotic Therapy With colcHicine and Low Dose Rivaroxaban for Major Adverse Cardiovascular Events Reduction in Ischemic Stroke (ARCHIMEDES)

Ischemic Stroke
Takeda

Not yet recruiting

A Study to Monitor the Adverse Events of QDENGA Vaccine in Participants in Malaysia (PRIME-Q)

Dengue Fever

Malaysia
Eli Lilly and Company

Not yet recruiting

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Renal Function in Adults Living With Obesity (TRIUMPH-OUTCOMES)

Overweight and Obesity

United States, Canada, Australia, Germany, Mexico, Argentina, Brazil, Hungary, Austria, India, Poland, Slovakia, Spain, Netherlands, Turkey, Czechia, United Kingdom, Denmark, Puerto Rico, France, Israel
Fondazione IRCCS Istituto Nazionale dei Tumori,...
Politecnico di Milano

Recruiting

Improving the Success Rate for Thoracic Radiotherapy Through Specific Cardiac Substructure Dosimetry: Location Matters. (LOCATION MATTERS) (LM)

Locally Advanced Lung Non-Small Cell Carcinoma

Italy
Sohag University

Not yet recruiting

Predictive Value of Serum Uric Acid to HDL Cholesterol Ratio for Diabetic Kidney Injury in Type 2 Diabetes

Diabetic Kidney Injury
Seoul National University Hospital
Astellas Pharma Inc

Recruiting

Tacrolimus Exposure in Kidney Transplantation

Kidney Transplant Rejection

Korea, Republic of
Centre Hospitalier Universitaire, Amiens

Recruiting

Predictive Value of Systolic Rise Time of the Plantar Arch on the Risk of Major Adverse Limb Events (MALE) and Major Adverse Cardiovascular Events (MACE) in Peripheral Artery Disease (PAD) at Critical Ischaemia Stage (TAMIS)

Peripheral Artery Disease | Critical Limb Ischemia | Major Adverse Cardiovascular Events | Major Adverse Limb Events | Hemodynamic Measure

France
Zhujiang Hospital

Not yet recruiting

Effectiveness of Atorvastatin in Preventing Cerebrovascular Events After Flow Diverter Implantation

Efficacy Endpoint: no New Cerebrovascular Adverse Events Within 1 Year | Safety Endpoint: no New Moderate or Serious Adverse Events Within 1 Year | All-cause Mortality Events (Within 1 Year) | Incident Ischemic Stroke Events (Within 1 Year) | New Hemorrhagic Stroke Events (Within 1 Year) | New... and other conditions
Guangzhou FineImmune Biotechnology Co., LTD.

Recruiting

Phase I Clinical Study of Tumor-associated Lymph Node T Cell Therapy for Advanced Solid Tumors (TAL-T)

Advanced Solid Tumor | Immunotherapy | Tumor Associated Lymph Node T Cell

China
AbbVie

Not yet recruiting

A Study Assessing Adverse Event and How Oral ABBV-453 Moves Through the Body in Adult Participants With Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma
Shandong Linglong Yingcheng Hospital

Recruiting

Protective Effect of Indocyanine Green Fluorescence Imaging Technology on Parathyroid Glands During Total Thyroidectomy

Indocyanine Green | Total Thyroidectomy | Parathyroid Function Low Adverse Event | Parathyroid Glands--Diseases

China
Jasper Gerritsen
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302) (RECSUR)

Glioblastoma | Glioblastoma Multiforme | Recurrent Glioblastoma | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult | Glioblastoma Multiforme of Brain | Astrocytoma of Brain | Astrocytoma, Malignant

United States, Germany, Netherlands, Switzerland, Belgium
Queensland Centre for Gynaecological Cancer
GlaxoSmithKline Research & Development Limited

Not yet recruiting

SATELLITE Study (feaSibility sAfeTy Efficacy dostarLimab earLy-stage defIcient endomeTrial cancEr) (SATELLITE)

Mmr Deficiency | Endometrial Cancer Stage I | Immune-related Adverse Event | Endometrioid Endometrial Adenocarcinoma

Australia
Insel Gruppe AG, University Hospital Bern
Swiss Cancer League

Not yet recruiting

Safety of Biliary Intraductal Radiofrequency Ablation in Patients With Unresectable Extrahepatic Biliary Tract Cancer (Ablatio)

Bile Duct Cancer

Switzerland
Beckman Coulter, Inc.

Recruiting

MACE CDS Software Master Enrollment Protocol

Cardiac Events

United States
AbbVie

Recruiting

A Study to Assess Adverse Events and Change in Disease Activity From Intravenous (IV) and Subcutaneous (SC) Lutikizumab in Adult Participants With Active Ulcerative Colitis

Ulcerative Colitis

United States
Chang Gung Memorial Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Hyperpolarized 13C-MRI and Metabolomics for Immune-related Adverse Events (DNP_irAE)

Immune-related Adverse Event

Taiwan
Université Catholique de Louvain
Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Not yet recruiting

QSPainRelief-STRAT (QSPR-STRAT)

Chronic Pain | Analgesia | Adverse Drug Event | Drug Interaction
Azienda Unità Sanitaria Locale Reggio Emilia

Recruiting

Rehabilitation Intervention to Prevent Adverse Events Related to Androgen-deprivation Therapy (ADT) in Patients With Metastatic Prostate Cancer (PCa): a Single Arm Feasibility Study (ReCaP Study) (ReCaP)

Rehabilitation | Metastatic Prostate Cancer (PCa) in ADT

Italy
AbbVie

Recruiting

Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (LIVIGNO-4)

Non-Small Cell Lung Cancer

United States, Israel, Japan
Jonsson Comprehensive Cancer Center

Not yet recruiting

Phase 2 Randomized Trial of Flexible Dosing Schedule of 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer (FLEX-MRT)

Prostate Carcinoma | Stage IVB Prostate Cancer American Joint Committee on Cancer (AJCC) v8

United States
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Safety Assessment of Concurrent Radiotherapy and Novel Systemic Therapy for Breast Cancer (RADIOCOM)

Chemotherapeutic Toxicity | Radiotherapy; Complications | PARP Inhibitor | Immune Checkpoint Inhibitor | Trastuzumab | Breast Cancer, Familial Male | CDK4/6 Inhibitor | Pertuzumab

China
AbbVie
Genmab

Recruiting

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma (EPCORE™FL-2)

Follicular Lymphoma (FL)

United States, Puerto Rico
Jun Wang

Recruiting

Thymosin Alpha-1 for irAE Secondary to ICIs

IrAE

China
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Recruiting

Effects of Diet and Osteopathy on Quality of Life and Inflammation in Breast Cancer Patients Under Hormonal Therapy (SECCO)

Breast Cancer

Italy
AbbVie

Recruiting

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving ABBV-383 as an Intravenous (IV) Infusion

Immunoglobulin Light Chain (AL) Amyloidosis

Japan, United States
Henrik Lindman

Recruiting

Effect of Salovum™ and SPC-Flakes™ on Abemaciclib-induced Gastrointestinal Toxicity in Early Breast Cancer (ASF-BC)

Diarrhea | Adverse Drug Event | Early-stage Breast Cancer

Sweden
Mayo Clinic

Recruiting

Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study

Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Hematopoietic and Lymphoid System Neoplasm

United States
First Affiliated Hospital Xi'an Jiaotong University
Shaanxi Provincial People's Hospital; Henan Provincial People's Hospital; 521... and other collaborators

Not yet recruiting

Response of Intracardiac Thrombus to Anticoagulants in Patients With Non-valvular Atrial Fibrillation (LYSIS) (LYSIS)

Atrial Fibrillation | Intracardiac Thrombus

China
AbbVie

Recruiting

A Study to Assess Adverse Events and Change of Masseter Muscle Prominence Using BOTOX Injections in Adult Participants

Masseter Muscle Prominence

Japan
Dana-Farber Cancer Institute
EMD Serono; National Comprehensive Cancer Network

Recruiting

Management of Cisplatin-Ineligible Patients With Metastatic Bladder Cancer and The Role of Geriatric Assessments

Bladder Cancer | Urothelial Carcinoma | Metastatic Bladder Cancer | Unresectable Bladder Carcinoma

United States
Kasr El Aini Hospital

Recruiting

Effect of Intranasal Midazolam Versus Ketamine Midazolam Combination as a Premedication on the Occurrence of Postoperative Respiratory Adverse Events

Tonsillectomy | Adenoidectomy | Drug-Related Side Effects and Adverse Reaction

Egypt
Shanghai Juncell Therapeutics

Recruiting

A Phase Ⅰb Study on Autologous GC101 TIL Injection for the Treatment of Advanced Melanoma (MIZAR-002) (MIZAR-002)

Melanoma | Efficacy | Adverse Drug Event | Safety | Tumor Infiltrating Lymphocytes

China
Insel Gruppe AG, University Hospital Bern
Charite University, Berlin, Germany; Kantonsspital Aarau; University of Lausanne... and other collaborators

Not yet recruiting

Prospective Assessment Project of AirwaY Management-related Incidents in Adult Anaesthesia Care PAPAYA III (PAPAYA-III)

Airway Complication of Anesthesia | Adverse Events

Germany, Switzerland
China National Center for Cardiovascular Diseases

Not yet recruiting

Low-dose Versus Standard-dose Rivaroxaban in Elderly Patients With Atrial Fibrillation

Stroke | Atrial Fibrillation | Major Adverse Cardiac Events | Anticoagulant Adverse Reaction
AbbVie

Recruiting

A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC) (LIVIGNO-2)

Hepatocellular Carcinoma

United States, Taiwan, Spain
AbbVie

Recruiting

Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab

Unresectable Metastatic Colorectal Cancer

Israel, United States, Japan, Korea, Republic of, Taiwan
Centro di Riferimento Oncologico - Aviano

Not yet recruiting

The Impact of Adverse Events, Produced by Antibodies Conjugates, on Quality of Life in Patients With Metastatic Breast Cancer: Multicentric, Observational Study (EVA). (EVA)

Metastatic Breast Cancer

Italy
AbbVie

Recruiting

A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab

Juvenile Psoriatic Arthritis

United States, Spain, Poland, Italy
Currax Pharmaceuticals

Recruiting

Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE) (INFORMUS)

Obesity

United States
AbbVie

Recruiting

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

Hepatocellular Carcinoma | Triple Negative Breast Cancer | Pancreatic Ductal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Biliary Tract Cancers | Hormone Receptor+/Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer | Head and Neck Squamous-Cell Carcinoma

United States, Israel, Japan, Puerto Rico
Xijing Hospital of Digestive Diseases
Ankang Central Hospital; Xi'an International Medical Center Hospital; The First... and other collaborators

Recruiting

High-concentration Small-volume Versus Low-concentration Large-volume Iodine Solution for Esophageal Chromoendoscopy

Esophageal Squamous Cell Carcinoma

China
AbbVie

Recruiting

A Study to Assess Adverse Events and Change in Disease Activity of Risankizumab Subcutaneous Induction Treatment for Moderately to Severely Active Crohn's Disease.

Crohn's Disease

United States, Canada, Israel, Taiwan, Japan, Korea, Republic of
Academisch Medisch Centrum - Universiteit van Amsterdam...
Celltrion

Recruiting

inDuctIon tREatment With subCuTaneous Infliximab for Crohn's Disease (DIRECTCD)

Bowel Disease | Inflammatory Disease | Disease Crohn

Netherlands
Tom Appleton
Western University; Canadian Research Group in Immuno-Oncology

Not yet recruiting

Early Adalimumab Induction for Immune Checkpoint Inhibitor Associated Inflammatory Arthritis

Inflammatory Arthritis | Immune-related Adverse Event
AbbVie

Recruiting

A Study to Assess Change in Disease Activity, Adverse Events, and How the Drug Moves Through the Body in Adult Participants Living With Human Immunodeficiency Virus (HIV) Receiving Intravenous (IV) Infusion of Budigalimab and/or ABBV-382

Human Immuno-deficiency Virus (HIV) Disease

United States, Puerto Rico, Japan, Spain, Germany, Canada, Belgium, France, Poland, South Africa
AbbVie

Recruiting

An Observational Study to Assess Change in Disease Activity and Adverse Events in Adolescent and Adult Participants With Moderate to Severe Active Crohn's Disease (CD) in Japan

Crohn's Disease

Japan
AbbVie

Recruiting

A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease

United States, Korea, Republic of, Taiwan, Israel, Switzerland, United Kingdom, Puerto Rico
Hospices Civils de Lyon

Recruiting

Investigational Biomarkers for Neurological Immune-related Adverse Events (NFL-ICI)

Neurological Disease

France

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