Search clinical trials for: Airflow Obstruction

Total 2299 results

AstraZeneca
Parexel

Not yet recruiting

A Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C)

Healthy

Germany
St. Joseph's Healthcare Hamilton
Trudell Medical International

Not yet recruiting

Effect of OPEP on Mucus Plugging and Airflow Obstruction in Patients With Moderate-to-severe Asthma (AeroMUC)

Asthma

Canada
University of Birmingham
Salford Royal Foundation Trust

Recruiting

Sputum Colour Charts to Guide Antibiotic Self-treatment of Acute Exacerbation of COPD (Colour COPD)

Pulmonary Disease, Chronic Obstructive

United Kingdom
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Longitudinal Observational Study of Severe Asthma

Asthma

United States
Virginia Hawkins

Completed

Does Severity of Airflow Obstruction Correlate to Static Lung Volumes

Pulmonary Disease, Chronic Obstructive

United Kingdom
University of Nebraska
VA Nebraska Western Iowa Health Care System

Completed

Airway Macrophages and Sputum Milieu in Adult Subjects With Airflow Obstruction

Pulmonary Disease, Chronic Obstructive | Occupational Diseases | Tobacco Use Disorder | Bronchitis, Chronic

United States
Tufts Medical Center
Virginia Commonwealth University

Active, not recruiting

Effects of High Flow Nasal Cannula on Sputum Clearance in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | COPD Exacerbation | Airflow Obstruction

United States
University Hospital Ostrava

Completed

Changes in Nasal Airflow Parameters After Septoplasty and Turbinoplasty

Nasal Obstruction | Nasal Septum; Deviation | Nasal Mucosa Hypertrophy

Czechia
Mesoblast, Inc.

Completed

PROCHYMAL™ (Human Adult Stem Cells) for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive | Pulmonary Emphysema | Chronic Bronchitis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of Fasting on the Asthma Inflammasome

Asthma

United States
Imperial College London

Unknown

Physiology and Structure of the Small Airways in Patients With Chronic Airflow Obstruction or COVID-19 (PASSPORT)

COVID-19 | Asthma | Copd | Small Airways Disease

United Kingdom
Forest Laboratories

Completed

Study To Assess Efficacy and Safety of Oglemilast in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States
New York City Health and Hospitals Corporation

Unknown

Thermal Imaging as a Potential Diagnostic Tool of Nasal Airflow

Nasal Airway Obstruction

United States
GlaxoSmithKline

Completed

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GlaxoSmithkline (GSK) Biologicals' Investigational Vaccine GSK2838504A When Administered to Chronic Obstructive Pulmonary Disease (COPD) Patients With Persistent Airflow Obstruction.

Respiratory Disorders

Sweden, United Kingdom
Queen's University

Completed

Effects of N-acetylcysteine on Cardiorespiratory Control in COPD Patients With Mild-to-moderate Airflow Obstruction

Pulmonary Disease, Chronic Obstructive
University of Cadiz
European Regional Development Fund

Completed

Feel Breathe, Restriction Device Ventilatory Nasal (COPD) (BreatheCOPD)

Chronic Obstructive Pulmonary Disease

Spain
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo; Conselho Nacional de...

Completed

Nasal and Oronasal Mask in Severe OSA Patients With Nasal Free Airflow of Obstruction

Obstructive Sleep Apnea of Newborn

Brazil
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory Asthma

Airway Inflammation | Severe, Refractory Asthma | Airflow Obstruction

United States
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Pioglitazone Hydrochloride (Actos(Registered Trademark)) to Treat Asthma

Asthma | Airway Inflammation | Airflow Obstruction | Airway Hyperactivity

United States
AstraZeneca

Terminated

Comparison of Aclidinium Bromide and Formoterol Fumarate in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States
AstraZeneca

Completed

Safety and Tolerability of Aclidinium Bromide/Formoterol Fumarate Compared With Formoterol Fumarate in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United States
AstraZeneca

Completed

Efficacy, Safety and Tolerability of Two Fixed Dose Combinations of Aclidinium Bromide/Formoterol Fumarate, Aclidinium Bromide, Formoterol Fumarate and Placebo for 28-Weeks Treatment in Patients With Moderate to Severe, Stable Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States, Australia, Canada, New Zealand
AstraZeneca

Completed

Long-term Safety, Tolerability and Efficacy of Aclidinium Bromide in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-35) (LAS-MD-35)

Chronic Obstructive Pulmonary Disease

United States, Canada
AstraZeneca

Completed

Efficacy, Safety and Tolerability of Aclidinium Bromide/Formoterol Fumarate Compared With Aclidinium Bromide and Formoterol Fumarate in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States, Australia, Canada, New Zealand
Ann & Robert H Lurie Children's Hospital of Chicago

Unknown

Early Detection and Management of Bronchiolitis Obliterans Syndrome Following Pediatric Hematopoietic Stem Cell Transplantation

Bronchiolitis Obliterans Syndrome

United States
AstraZeneca

Completed

Efficacy and Safety Study of Two Fixed-dose Combinations of Aclidinium Bromide With Formoterol Fumarate Compared With Aclidinium Bromide, Formoterol Fumarate and Placebo (LAC-MD-27)

Chronic Obstructive Pulmonary Disease

United States
Walter Reed National Military Medical Center

Completed

Airflow Perturbation Device (APD) for the Evaluation of Pulmonary and Sleep Disorders

Airway Obstruction
AstraZeneca

Completed

Pharmacokinetic, Safety and Tolerability Study of Aclidinium/Formoterol Fixed Dose Combination and Formoterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Invion, Inc.

Completed

Efficacy and Safety of Βeta-adrenoceptor Inverse Agonist and Biased Ligand, Nadolol, In Smoking Cessation of Patients With Chronic Cough With or Without Airflow Obstruction

Smoking Cessation

United States
AstraZeneca

Completed

Efficacy, Safety, and Tolerability of Aclidinium Bromide in the Treatment of Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-38) (LAS-MD-38)

Chronic Obstructive Pulmonary Disease

United States, Canada
AstraZeneca

Completed

Efficacy and Safety of Aclidinium Bromide for Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-33)

Chronic Obstructive Pulmonary Disease

United States, Canada
AstraZeneca

Completed

Long-term Extension Study of the Safety, Tolerability, and Efficacy of Aclidinium Bromide in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-36)

Chronic Obstructive Pulmonary Disease

United States, Canada
Mundipharma Research Limited

Terminated

A Study to Compare Fluticasone /Formoterol Breath Actuated Inhaler (BAI) and Ultibro in Subjects With Fixed Airflow Obstruction and Elevated Eosinophils

ACOS (Fixed Airflow Obstruction and Elevated Eosinophils)

Slovakia
Breathe Technologies, Inc.

Completed

Non-invasive Ventilation System in Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) (PRIDE)

Pulmonary Disease, Chronic Obstructive | Chronic Obstructive Lung Disease | Chronic Obstructive Airway Disease | Airflow Obstruction, Chronic

United States
Breathe Technologies, Inc.

Completed

In-home Evaluation of a Noninvasive Open Ventilation System in Patients With Severe Respiratory Insufficiency

Pulmonary Disease, Chronic Obstructive | Chronic Obstructive Lung Disease | Chronic Obstructive Airway Disease | Airflow Obstruction, Chronic

United States
Corporal Michael J. Crescenz VA Medical Center

Completed

Study of Default Options in Advance Directives

Idiopathic Pulmonary Fibrosis | COPD | Congestive Heart Failure | Malignancy | Severe or Very Severe Airflow Obstruction and/or Receiving or Eligible to Receive Long-term Oxygen Therapy | Other Interstitial Lung Disease Without Curative Therapy | NYHA Class IV or NYHA Class III Plus 1 Hospitalization... and other conditions

United States
Imperial College London

Unknown

Cardiopulmonary Exercise Testing to Evaluate Pulmonary AVMs With and Without Airflow Obstruction (ExercisePAVM2)

Asthma | COPD | Hereditary Hemorrhagic Telangiectasia | Pulmonary Arteriovenous Malformations
Arthur F Gelb MD

Completed

Evaluation Inhaled Corticosteroids on Exhaled Nitric Oxide Gas Exchange

COPD

United States
ROX Medical, Inc.

Completed

Study of the Effect of the ROX AC1 on Exercise Capacity and Quality of Life in Chronic Obstructive Pulmonary Disease (COPD) Patients

Chronic Obstructive Pulmonary Disease

Germany
ROX Medical, Inc.

Completed

A Pilot Study to Evaluate the ROX Anastomotic Coupler System in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United States
Paracelsus Medical University

Completed

SCOPE-Study: Salzburg Chronic Obstructive Pulmonary Disease- Exercise and Oxygen Study (SCOPE)

Chronic Obstructive Pulmonary Disease

Austria
St. Joseph's Healthcare Hamilton
GlaxoSmithKline

Withdrawn

How Airway Remodeling and Hyperresponsiveness Contribute to Airflow Obstruction in Asthma

Asthma

Canada
The University of Hong Kong

Unknown

A Study on Smoking-related Lung Function Abnormalities and Correlation With Serum Biomarkers in Chinese

Chronic Airflow Obstruction

Hong Kong
Seattle Children's Hospital
AstraZeneca

Completed

Airflow Obstruction and Biomarkers of Airway Inflammation During and Following Acute Exacerbations of Childhood Asthma

Asthma

United States
Medical Center Alkmaar

Unknown

Expiratory Airflow Limitation in Subjects With Obesity (EFL)

Obesity
Assiut University

Recruiting

Lap Adhesiolysis in Intestinal Obstruction

Adhesions Bowel

Egypt
ENTire Medical Ltd.

Recruiting

Efficacy And Safety of An IRE System For Treatment of Inferior Turbinate Hypertrophy

Nasal Obstruction | Inferior Turbinate Hypertrophy | Turbinate; Hypertrophy Mucous Membrane

Israel, Lithuania
Sun Yat-sen University

Recruiting

The Efficacy of Bevacizumab and Serplulimab Combined With Recombinant Mutant HumanTumor Necrosis Factor(rmhTNF-NC) in the Treatment of Malignant Ascites

Malignant Ascites

China
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy (SOTA-CROSS HCM)

Hypertrophic Cardiomyopathy Without Obstruction
Institut universitaire de cardiologie et de pneumologie...

Not yet recruiting

Valve Performance of the SAPIEN 3 Ultra RESILIA Valve: A Prospective Registry With Central Echocardiography Analysis.

Aortic Valve Stenosis | Transcatheter Aortic Valve Replacement

Canada

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