Search clinical trials for: Alveolar Macrophage

Total 1383 results

Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI); University of South Florida

Recruiting

Safety and Efficacy of PMT Therapy of hPAP

Hereditary Pulmonary Alveolar Proteinosis

United States
University of Edinburgh

Recruiting

Innate Immunity in COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Southeast University, China

Recruiting

Study on the Correlation Between Alveolar Macrophage-derived Autophagosomes and the Severity of Lung Injury in ARDS

ARDS

China
Assistance Publique - Hôpitaux de Paris

Recruiting

Macrophages, GM-CSF and MARS Proteinosis (MacroMARS)

Genetic Mutation | Pulmonary Alveolar Proteinosis (PAP) | MARS

France
National Jewish Health

Recruiting

Alveolar Macrophage Programming Following Endotoxin Exposure

ARDS, Human

United States
National Institute of Allergy and Infectious Diseases...

Completed

Rituximab for Anti-cytokine Autoantibody-Associated Diseases

Pulmonary Alveolar Proteinosis (PAP) | Severe Mucocutaneous Candidiasis

United States
Spero Therapeutics

Completed

A Study to Assess the Intrapulmonary Pharmacokinetics (PK) of SPR719 by Comparing the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations Following the Oral Administration of Multiple Doses of SPR720 in Healthy Volunteers.

Healthy Volunteer

United States
Rempex Pharmaceuticals (a wholly owned subsidiary...
Innovative Medicines Initiative; Universitätsklinikum Köln

Withdrawn

Safety and PK Trial Evaluating the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations of Minocin IV

Normal Healthy Volunteers

Austria
Children's Hospital Medical Center, Cincinnati
Genzyme, a Sanofi Company; Virginia Commonwealth University

Completed

Inhaled Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) in Hereditary Pulmonary Alveolar Proteinosis (PAP) (FAMPAP)

Hereditary Pulmonary Alveolar Proteinosis

United States
Prof. Dr. Jens Hohlfeld

Completed

Activation of Apoptosis-related Receptors on Alveolar Macrophages

Chronic Obstructive Pulmonary Disease

Germany
Savara Inc.

Active, not recruiting

Clinical Trial of Inhaled Molgramostim Nebulizer Solution in Autoimmune Pulmonary Alveolar Proteinosis (aPAP) (IMPALA-2)

Autoimmune Pulmonary Alveolar Proteinosis

United States, Korea, Republic of, United Kingdom, Netherlands, Australia, Romania, Japan, Portugal, Canada, Greece, Spain, Italy, Poland, Belgium, France, Germany, Ireland, Turkey
IRCCS Policlinico S. Matteo
Agenzia Italiana del Farmaco

Completed

Inhaled GM-CSF Therapy of Autoimmune PAP

Autoimmune Pulmonary Alveolar Proteinosis

Italy
University Hospital, Ghent
Flanders Institute of Biotechnology

Completed

Sargramostim in Patients With Acute Hypoxic Respiratory Failure Due to COVID-19 (SARPAC) (SARPAC)

COVID-19

Belgium
VA Ann Arbor Healthcare System
University of Michigan

Completed

Modulation of Steroid Immunosuppression by Alveolar Efferocytosis

Pulmonary Disease, Chronic Obstructive | Pneumonia, Bacterial

United States
Spero Therapeutics
United States Department of Defense

Completed

Study to Assess the Intrapulmonary Pharmacokinetics of SPR206 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Ohio State University

Completed

Functional Proteomics of Alveolar Macrophages

COPD

United States
Philip Diaz
National Institutes of Health (NIH)

Completed

Alveolar Macrophage Proteomics in HIV-associated Emphysema (HIVE)

HIV Infections | Emphysema | HIV

United States
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

HIV+ Alveolar Macrophage Oxidant-mediated Apoptosis of Pulmonary Endothelium

Smoking | Emphysema | HIV | COPD

United States
VA Office of Research and Development

Completed

Examination of Zinc, S-adenosylmethionine, and Combination Therapy Versus Placebo in Alcoholics (ExZACTO)

Alcoholism

United States
Spero Therapeutics
Clinartis

Completed

Study to Assess the Intrapulmonary Pharmacokinetics of SPR859 by Comparing the Plasma, Epithelial Lining Fluid (ELF), and Alveolar Macrophages (AM) Concentrations Following the Oral Administration of Five Doses of SPR994 in Healthy, Nonsmoking Volunteers

Healthy Volunteers

United States
National Jewish Health

Completed

The Role of JAK2 in Alveolar Macrophages (AM's) in Chronic Beryllium Disease (CBD)

Chronic Beryllium Disease (CBD) | Beryllium Sensitization (BeS)

United States
University Hospital, Clermont-Ferrand

Completed

A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study

Acute Respiratory Distress Syndrome | Mechanical Ventilation

France
Emory University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Researching Alveolar Macrophage Improvements With Supplements in HIV (RAISe)

HIV-1 Infection

United States
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

Evaluating the Plasma, Epithelial Lining, and Alveolar Macrophage Concentrations of Intravenous Carbavance™ (RPX2014/RPX7009) in Healthy Adult Subjects

Healthy Subjects

United States
Entasis Therapeutics
Clinartis

Completed

Study to Determine and Compare Plasma and Intrapulmonary Concentrations of ETX2514 and Sulbactam in Healthy Subjects

Healthy

United States
Dai Huaping

Unknown

Sequential Therapy With WLL/Inhaling GM-CSF for Autoimmune Pulmonary Alveolar Proteinosis

Treatment | Pulmonary Alveolar Proteinosis

China
Rennes University Hospital

Unknown

Phenotypic Characterization of Alveolar Macrophages 2016 (Caract-Aires-2016) (Caract-Aires)

Lung Diseases

France
Savara Inc.
Celerion

Completed

Inhaled Molgramostim (rhGM-CSF) in Healthy Adult Subjects

Bronchiectasis | Cystic Fibrosis | Acute Respiratory Distress Syndrome | Pulmonary Alveolar Proteinosis

United Kingdom
West China Hospital

Unknown

Changes in Alveolar Macrophage Function During Acute Lung Injury

Acute Lung Injury
VA Office of Research and Development

Completed

Apoptotic Cell (AC) Uptake by Human Alveolar Macrophages (AM)

Chronic Obstructive Pulmonary Disease

United States
The Cleveland Clinic

Terminated

GM-CSF in Patients With Pulmonary Alveolar Proteinosis

Pulmonary Alveolar Proteinosis

United States
University of Michigan
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Comparison of Alveolar Macrophages in Individuals With COPD Versus Smokers With Normal Pulmonary Function

Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive

United States
Peking Union Medical College Hospital
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical...

Unknown

Inhalation of Granulocyte-macrophage Colony-stimulating Factor (GM-CSF) for Autoimmune Pulmonary Alveolar Proteinosis (PAP)

Autoimmune Pulmonary Alveolar Proteinosis

China
Shanghai Pulmonary Hospital, Shanghai, China

Unknown

Study of Subcutaneous Injection of Low-dose rhGM-CSF +/- WLL in PAP. (PAP)

Pulmonary Alveolar Proteinosis

China
University of Michigan
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Comparison of Alveolar Macrophages in Healthy Individuals Versus Individuals With COPD

Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive

United States
Keith A. Rodvold
Pulmonary Associates, PA

Completed

Doripenem Intrapulmonary Pharmacokinetics in Healthy Adult Subjects

Healthy

United States
Nanjing Medical University
HRSA/Maternal and Child Health Bureau

Completed

Influence of Propofol on Alveolar Macrophage in Asthmatic Patients (PAMAP)

Asthma

China
University of Bari Aldo Moro

Not yet recruiting

Tunnel Access for Horizontal Alveolar Ridge Augmentation

Bone Loss | Bone Resorption | Alveolar Bone Loss | Bone Atrophy, Alveolar | Alveolar Bone Resorption

Italy
University of Sao Paulo General Hospital

Recruiting

Respiratory Mechanics Assessment at Different Head of the Bed Elevations in Mechanically Ventilated Patients

Respiratory Failure | Pulmonary Disease

Brazil
Swedish Orphan Biovitrum

Recruiting

Assessment of Macrophage Activation syndromE in STill's Disease (AMETHYST)

Still's Disease, Adult-Onset | Macrophage Activation Syndrome | Stills Disease, Juvenile-Onset

United States, Canada, France, Germany, Italy, Netherlands, Spain
NYU Langone Health

Recruiting

ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer

Prostate Cancer

United States
Southeast University, China

Not yet recruiting

Epidemiology and Treatment Strategy of Open Respiratory Phenotype in Critically Ill Patients

Critical Illness | Mechanical Ventilation Pressure High

China
Mansoura University

Not yet recruiting

Immediate Dental Implants in The Upper Anterior Region

Alveolar Bone Resorption | Teeth Loss

Egypt
Universidad de Granada

Recruiting

Extraction Socket Augmentation. A Clinical Study (GTO)

Edentulous Alveolar Ridge With Labial Resorption

Spain
Cairo University

Not yet recruiting

Autogenous Demineralized Dentin Graft Combined With Injectable PRF + Metronidazole Versus Autogenous Demineralized Dentin Graft Combined With Injectable PRF Versus Autogenous Demineralized Dentin Graft Alone for Alveolar Ridge Preservation

Alveolar Bone Loss

Egypt
Esraa Salem Kamal

Recruiting

OSSEODENSIFICATION BY DENSAH BURS WITH ACTIVATED PLASMA ALBUMIN GEL FOR SINUS LIFTING WITH SIMULTANEOUS IMPLANT PLACEMENT

Bone Loss, Alveolar

Egypt
Cairo University

Not yet recruiting

Alveolar Cleft Reconstruction Using Bone Marrow Aspirate Concentrate and Allograft vs Iliac Cancellous Bone. (BMAC)

Alveolar Cleft Grafting

Egypt
Ain Shams University
British University In Egypt

Recruiting

Soft Tissue Volume, Dimensions and Tomographic Alveolar Ridge Classification System for Dental Implant Treatment.

Soft Tissue Volume

Egypt
Cairo University

Not yet recruiting

Clinical Evaluation of Anaesthetic Efficacy of 4% Articaine Buccal Infiltration Versus Inferior Alveolar Nerve Block

Restorative Dental Treatment by Buccal Infiltration Anaesthesia
Second Affiliated Hospital of Soochow University

Not yet recruiting

PRaG Therapy in Combination With Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC) (NeoPRAG Study)

Pancreatic Ductal Adenocarcinoma

Search clinical trials for: Alveolar Macrophage

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