Search clinical trials for: Anakinra

Total 176 results

Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Bayesian Basket Trial (PALETTE)

Sepsis
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Randomized Controlled Trial in Patients on Long-term Colchicine With Colchicine-resistant Familial Mediterranean Fever (FMF) to Evaluate the Efficacy of On-demand Anakinra Treatment for Painful Attacks in Patients Who Refuse Continuous Daily Therapy (KIN-ATTACK-FMF)

FMF

France
Azienda Ospedaliero, Universitaria Ospedali Riuniti

Recruiting

Therapy Management in Patients Treated With Anakinra Due to Recurrent Pericarditis

Recurrent Pericarditis

Italy
Virginia Commonwealth University

Recruiting

The Effects of IL-1 Blockade on Inotrope Sensitivity in Patients With Heart Failure (AID-HEART) (AID-HEART)

Heart Failure

United States
Sydney Local Health District

Not yet recruiting

BivaLirudin versUS Heparin in Extracorporeal Membrane Oxygenation (BLUSH)

Extracorporeal Membrane Oxygenation Complication

Australia
Hellenic Institute for the Study of Sepsis

Recruiting

Safety and Efficacy of Anakinra Treatment for Patients With Post Acute Covid Syndrome (PRECISION)

Long COVID | Post-Acute COVID-19 | Post-Acute COVID-19 Syndrome

Germany, Greece, Italy, Spain
Azienda Sanitaria-Universitaria Integrata di Udine
University of Udine

Recruiting

Efficacy and Safety of Anakinra in Acute Respiratory Distress Syndrome (ESKA)

Acute Respiratory Distress Syndrome

Italy
University Hospital, Basel, Switzerland

Recruiting

Hyperinsulinemia in Prediabetes Mediated by Interleukin-1β (Hyper-PreDIL)

PreDiabetes | Hyperinsulinemia

Switzerland
Swedish Orphan Biovitrum
CMIC Co, Ltd. Japan

Recruiting

A Study of Anakinra in Japanese Patients With Still's Disease (SJIA and AOSD)

Still's Disease, Adult-Onset | Still's Disease, Juvenile Onset

Japan
Istituto Giannina Gaslini

Not yet recruiting

Therapeutic Approach in Colchicine-resistant Recurrent pEricarditis in Children (CREATE)

Pericarditis
Oxford University Clinical Research Unit, Vietnam
Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam

Recruiting

Anakinra in Dengue With Hyperinflammation ( AnaDen )

Cytokine Storm | Dengue | Severe Dengue | Macrophage Activation Syndrome | Anakinra | Dengue With Warning Signs | Anti-inflammatory Agents | Hyperinflammatory Syndrome | Immuno-modulation

Vietnam
Herlev and Gentofte Hospital

Not yet recruiting

The Role of Interleukin-1 Beta Targeted Therapy for Patients Suffering From Allergic Contact Dermatitis

Allergic Contact Dermatitis
Monash Medical Centre
Monash University; University of Auckland, New Zealand; Hudson Institute of Medical... and other collaborators

Recruiting

Anakinra for Preterm Infants Pilot

Inflammation | Prematurity; Extreme

Australia, New Zealand
Democritus University of Thrace

Recruiting

Combination of Inhaled DNase, Baricitinib and Tocilizumab in Severe COVID-19

COVID-19 Severe Respiratory Failure

Greece
Nationwide Children's Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS (TRIPS)

Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)

United States
Virginia Commonwealth University
National Institute on Aging (NIA); University of Virginia

Recruiting

Interleukin-1 Blockade in Acute Myocardial Infarction to Prevent Heart Failure (Virginia-ART4)

Heart Failure

United States
Medical University of Vienna
Medical University of Graz; Medical University Innsbruck; Hospital Hietzing; Krankenhaus...

Not yet recruiting

Screening for Flare After b/tsDMARD Discontinuation in Rheumatoid Arthritis

Rheumatoid Arthritis
Alan Prossin
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Discovery and Analytical Validation of Inflammatory Bio-signatures of the Human Pain Experience

Pain

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Astex Pharmaceuticals, Inc.

Recruiting

ASTX727 and Dasatinib for the Treatment of Newly Diagnosed Philadelphia Chromosome or BCR-ABL Positive Chronic Myeloid Leukemia in Chronic Phase

Chronic Phase Chronic Myelogenous Leukemia | Philadelphia Chromosome Positive | BCR-ABL1 Positive Chronic Myelogenous Leukemia | BCR-ABL1 Positive

United States
Baylor Research Institute

Not yet recruiting

Chemotherapy + Anakinra in Patients With Pancreatic Adenocarcinoma (PDAC)

Pancreatic Adenocarcinoma

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Anakinra vs Prednisone to Treat Gout Flare in Patients With Chronic Kidney Disease Stage 4/5 or Renal Transplantation (Ana4CKD)

Chronic Kidney Disease | Gout | Renal Transplantation

France
Radboud University Medical Center
Dutch Heart Foundation

Recruiting

Studying Anakinra to Reduce Secondary Brain Damage After Spontaneous Haemorrhagic Stroke (ACTION)

Intracerebral Hemorrhage

Netherlands
Assistance Publique - Hôpitaux de Paris
Swedish Orphan Biovitrum

Recruiting

A Trial Comparing the Efficacy and Safety of Anakinra Versus Intravenous Immunoglobulin (IVIG) Retreatment, in Patients With Kawasaki Disease Who Failed to Respond to Initial Standard IVIG Treatment (ANACOMP)

Kawasaki Disease

France
Karolinska University Hospital
Karolinska Institutet

Recruiting

A Study in Patients With COVID-19 and Respiratory Distress Not Requiring Mechanical Ventilation, to Compare Standard-of-care With Anakinra and Tocilizumab Treatment The Immunomodulation-CoV Assessment (ImmCoVA) Study

Covid-19

Sweden
Guy's and St Thomas' NHS Foundation Trust
Monash University; Australian and New Zealand Intensive Care Research Centre; Royal Surrey County Hospital NHS Foundation Trust

Recruiting

Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome (ACES)

COVID | Acute Respiratory Distress Syndrome

United Kingdom
University of Oxford
Bill and Melinda Gates Foundation; Department for International Development... and other collaborators

Recruiting

Randomised Evaluation of COVID-19 Therapy (RECOVERY)

Severe Acute Respiratory Syndrome

Ghana, Indonesia, Nepal, South Africa, United Kingdom, Vietnam, India
Fred Hutchinson Cancer Center
Swedish Orphan Biovitrum

Recruiting

Anakinra for the Prevention of Cytokine Release Syndrome and Neurotoxicity in Patients With B-Cell Non-Hodgkin Lymphoma Receiving CD19-Targeted CAR-T Cell Therapy

B-Cell Non-Hodgkin Lymphoma

United States
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditions

United States, Canada
University Hospital, Basel, Switzerland

Recruiting

IL-1-receptor Antagonist During Cephalic Phase of Insulin Secretion in Health and Type 2 Diabetes (Cephalira)

Inflammation | Metabolic Disease | Diabetes Mellitus Type 2 in Obese | Glucose Metabolism Disorders (Including Diabetes Mellitus)

Switzerland
Jonsson Comprehensive Cancer Center

Recruiting

Anakinra in Preventing Severe Chimeric Antigen Receptor T-Cell Related Encephalopathy Syndrome in Patients With Recurrent or Refractory Large B-cell Lymphoma

Progressive Disease | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma | Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma | Refractory High Grade B-Cell Lymphoma | Refractory Transformed Follicular... and other conditions

United States
Virginia Commonwealth University
American Heart Association; National Center for Advancing Translational Sciences...

Recruiting

Interleukin-1 Blockade for Treatment of Cardiac Sarcoidosis (MAGiC-ART)

Cardiac Sarcoidosis

United States
University of California, San Diego

Recruiting

Pilot Study of the IL-1 Antagonist Anakinra for the Treatment of Endometriosis Related Symptoms

Endometriosis | Anakinra | Markers of Inflammation

United States
University of California, Los Angeles
Orthopedic Research and Education Foundation

Recruiting

Biologic Therapy to Prevent Osteoarthritis After ACL Injury

Anterior Cruciate Ligament Injuries

United States
Heidelberg University

Recruiting

A Study to Evaluate Safety and Efficacy of Subcutaneous Administration of Anakinra in Patients With CF (ANAKIN)

Cystic Fibrosis, 10011762

Germany
Virginia Commonwealth University

Recruiting

Interleukin-1 Blockade In Recently Decompensated Heart Failure - 2 (REDHART2)

Inflammation | Heart Failure, Systolic

United States
Northwell Health
Swedish Orphan Biovitrum

Recruiting

Effects of Anakinra in Subjects With Corticosteroid-resistant/Intolerant Meniere's Disease and Autoimmune Inner Ear Disease

Meniere's Disease | Autoimmune Inner Ear Disease

United States
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Lactating Women on Select DOI | Breastfed Infants of Mothers on Select DOI

United States, Canada
Russell Richardson

Recruiting

: Vascular Function in Health and Disease

Heart Failure | Hypertension | Chronic Obstructive Pulmonary Disease | Pulmonary Artery Hypertension

United States
UMC Utrecht
National University Hospital, Singapore; Berry Consultants; University of Pittsburgh... and other collaborators

Recruiting

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia (REMAP-CAP)

Community-acquired Pneumonia, Influenza, COVID-19

United Kingdom, United States, Canada, Australia, Netherlands, Croatia, Germany, Belgium, New Zealand, Ireland, Spain, Japan, Hungary, Colombia, India, Nepal, Pakistan, Portugal, Romania, Saudi Arabia
Marcela V. Maus, M.D.,Ph.D.
Kite, A Gilead Company

Active, not recruiting

A Phase 2 Trial of Anakinra for the Prevention of CAR-T Cell Mediated Neurotoxicity

Non Hodgkin Lymphoma | Neurotoxicity | Neurotoxicity Syndromes | Cytokine Release Syndrome | Refractory Non-Hodgkin Lymphoma | Relapsed Non Hodgkin Lymphoma

United States
Sheba Medical Center

Completed

Kineret (Anakinra), in Adult Patients With Colchicine-Resistant Familial Mediterranean Fever (FMF)

Familial Mediterranean Fever

Israel
Hellenic Institute for the Study of Sepsis

Active, not recruiting

Use of Presepsin as a Marker for Immunotherapy Administration in Pneumonia (INSPIRE)

Hospital-acquired Pneumonia | Community-acquired Pneumonia

Greece
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Anakinra for the Reduction of CAR-T Toxicity in Patients With Relapsed or Refractory Large B-cell Lymphoma

Hematopoietic and Lymphoid Cell Neoplasm | Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma | Recurrent... and other conditions

United States
Assistance Publique - Hôpitaux de Paris

Completed

Anakinra Versus Placebo for the Treatment of Acute MyocarditIS (ARAMIS)

Acute Myocarditis

France
University of California, San Diego
Boston Children's Hospital; Cedars-Sinai Medical Center

Completed

Anakinra in Infants and Children With Coronary Artery Abnormalities in Acute Kawasaki Disease

Kawasaki Disease

United States
University of Alabama at Birmingham

Active, not recruiting

Treatment of Macrophage Activation Syndrome (MAS) With Anakinra (MAS)

Macrophage Activation Syndrome

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

A Study of Anakinra to Prevent or Treat Severe Side Effects for Patients Receiving CAR-T Cell Therapy

B-Cell Lymphoma | B-cell Non Hodgkin Lymphoma | B Cell ALL

United States
Lundquist Institute for Biomedical Innovation at...
Swedish Orphan Biovitrum; Cure Sanfilippo Foundation

Completed

Open-label Study of Anakinra in MPS III

Mucopolysaccharidosis III

United States
University Hospital, Basel, Switzerland

Active, not recruiting

Empagliflozin and Anakinra for the Treatment of Postprandial Hypoglycemia in Patients With Prediabetes (Hypo-PrEA)

Postprandial Hypoglycemia

Switzerland
Charite University, Berlin, Germany
Max Planck Institute for Infection Biology

Completed

Safety and Tolerability of Anakinra in Combination With Riluzol in Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS)

Germany

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