Search clinical trials for: Background Factors

Total 31642 results

Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor (AQUA)

Dermatitis Atopic

Chile, United Kingdom, United States, Canada, Turkey, Israel, Korea, Republic of
Peking Union Medical College Hospital
The First Affiliated Hospital of Anhui Medical University; Peking University... and other collaborators

Recruiting

Study of Pomalidomide, Oral Dexamethasone and Ixazomib in Patients With Relapsed MM Who Have Received Lenalidomide

Multiple Myeloma

China
Alexion

Recruiting

Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN) (SANCTUARY)

Lupus Nephritis | Immunoglobulin A Nephropathy

United States, Australia, Canada, France, Germany, Italy, Korea, Republic of, Netherlands, Poland, Singapore, Spain, Sweden, Taiwan, United Kingdom
Melanoma Institute Australia

Recruiting

A Study to Evaluate Neoadjuvant Sonidegib Followed by Surgery or Imiquimod in the Management of Basal Cell Carcinoma (SONIB)

Skin Cancer | Basal Cell Carcinoma | Invasive Carcinoma | Basal Cell Carcinoma of Skin, Site Unspecified

Australia
IRCCS Fondazione Stella Maris

Completed

Quality of Life in Children With Cerebral Palsy

Unilateral and Bilateral Cerebral Palsy

Italy
Amgen

Completed

Efficacy, Safety, and Tolerability Study of Apremilast to Treat Early Oligoarticular Psoriatic Arthritis. (FOREMOST)

Arthritis, Psoriatic

United States, Spain, Netherlands, Canada, France, Russian Federation, Belgium, Austria, Germany, Italy, United Kingdom
Bristol-Myers Squibb

Active, not recruiting

A Study to Compare the Response to Treatment With Abatacept vs Adalimumab, on Background Methotrexate, in Adults With Early, Seropositive, and Shared Epitope-positive Rheumatoid Arthritis and an Inadequate Response to Methotrexate

Rheumatoid Arthritis

Italy, United States, Germany, Argentina, Australia, Czechia, France, Japan, Mexico, Poland, Spain, Switzerland, Taiwan, United Kingdom
Centre Hospitalier Universitaire de Saint Etienne

Terminated

Stress Induced by the COVID-19 Pandemic and Nonconfinement: Study of Anxiety Factors and Potential Effects on Immunity. (SCEI)

Stress Disorder

France, United Kingdom
GlaxoSmithKline
Human Genome Sciences Inc., a GSK Company

Active, not recruiting

Pediatric Lupus Trial of Belimumab Plus Background Standard Therapy (PLUTO)

Systemic Lupus Erythematosus

Peru, United States, Spain, Argentina, United Kingdom, Poland, Canada, Russian Federation, Japan, Mexico
Takeda

Completed

A Study to Evaluate the Efficacy and Safety of Ixazomib in Combination With Lenalidomide and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma Initially Treated With an Injection of Proteasome Inhibitor-Based Therapy

Relapsed and/or Refractory Multiple Myeloma

Japan
Massachusetts General Hospital
Millennium Pharmaceuticals, Inc.

Completed

MLN 9708 in Induction and Consolidation for Adults With AML >= 60 Years of Age

Acute Myeloid Leukemia

United States
Sciensano

Completed

COVID-19 Vaccination Uptake in Belgium : Sociodemographic and Socioeconomic Disparities

COVID-19

Belgium
Mayo Clinic

Completed

Environmental Factors to Increase Patient Comfort During Urodynamics Testing

Urologic Diseases | Lower Urinary Tract Symptoms

United States
University of California, Los Angeles

Withdrawn

Abatacept vs Placebo in RA Patients With Hepatitis B on Entecavir Background (RA)

Rheumatoid Arthritis | Chronic Hepatitis B

United States
University of Ljubljana, Faculty of Medicine

Completed

The Influence of Psychobiological Adversity to Children and Adolescents With Type 1 Diabetes

Stress | Type 1 Diabetes

Slovenia
Takeda

Withdrawn

A Study of Ixazomib, Thalidomide and Dexamethasone in Newly Diagnosed and Treatment-naive Multiple Myeloma (MM) Participants Non-eligible for Autologous Stem-cell Transplantation (IDEALL)

Multiple Myeloma

Brazil
Eli Lilly and Company

Completed

Oral Baricitinib (LY3009104)Treatment in Japanese Participants With Active Rheumatoid Arthritis on Background Methotrexate Therapy

Arthritis, Rheumatoid

Japan
Seattle Children's Hospital
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific

United States
Acerta Pharma BV

Completed

ACP-196 Versus Placebo in Subjects With Rheumatoid Arthritis on Background Methotrexate

Rheumatoid Arthritis

United States
Gilead Sciences

Completed

Safety, Tolerability, and Efficacy of GS-9876 in Participants With Active Rheumatoid Arthritis on Background Therapy With Methotrexate

Rheumatoid Arthritis

United States, Czechia, Bulgaria, Poland, Georgia, Moldova, Republic of, Ukraine
Eli Lilly and Company

Terminated

A Rheumatoid Arthritis Study in Participants on a Background Treatment of Methotrexate (FLEX M)

Rheumatoid Arthritis

Argentina, India, Korea, Republic of, Japan, United States, Hungary, Bulgaria, Russian Federation, Ukraine, Colombia, Mexico, Poland, Croatia, Taiwan, New Zealand, Romania, South Africa, Australia, Brazil, Lithuania, Malaysia, Slo... and more
Genentech, Inc.

Completed

A Study to Evaluate the Effects of Rituximab on Immune Responses in Subjects With Active Rheumatoid Arthritis Receiving Background Methotrexate (SIERRA)

Rheumatoid Arthritis

United States
PD Dr. med. Volker Heinemann
Boehringer Ingelheim

Unknown

Afatinib as Cancer Therapy for Exocrine Pancreatic Tumours (ACCEPT)

Focus of Study Instead

Germany
Eli Lilly and Company
Incyte Corporation

Completed

A Study in Participants With Rheumatoid Arthritis on Background Methotrexate Therapy

Arthritis, Rheumatoid

Hungary, Romania, United States, Czechia, Croatia, Poland, Ukraine, Mexico, India
Bristol-Myers Squibb

Completed

An Exploratory Study of Changes in Synovial Immune Responses Following BMS-188667 Therapy in Subjects With Active Rheumatoid Arthritis on Background DMARDs Who Have Failed Anti-TNF Therapy

Rheumatoid Arthritis

United Kingdom
The First People's Hospital of Hefei
Anhui Provincial Cancer Hospital; Simcere Pharmaceutical Co., Ltd; Anhui Jimin...

Unknown

Application of Two Anti-angiogenesis Drugs Combined With Chemotherapy in Advanced Colorectal Cancer Under the Background of Precision Medical

Colorectal Neoplasms

China
Pfizer

Completed

Study Comparing Etanercept (ETN) Against a Placebo for Etanercept on a Background Nonsteroidal Anti Inflammatory Drug (NSAIDs) in the Treatment of Early Spondyloarthritis (SpA) Patients Who do Not Have X-ray Structural Changes (EMBARK)

Spondylitis, Ankylosing

Belgium, Korea, Republic of, Spain, France, Taiwan, Germany, Argentina, Czech Republic, United Kingdom, Hungary, Russian Federation, Colombia, Finland, Netherlands
National Cancer Institute (NCI)

Completed

Comparing Three Different Combination Chemotherapy Regimens in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States, Israel
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Autologous Peripheral Stem Cell Transplant in Treating Patients With Stage III, Stage IV, or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cavity Cancer
TaiMed Biologics Inc.

Completed

Dose-Response Study of Ibalizumab (Monoclonal Antibody) Plus Optimized Background Regimen in Patients With HIV-1 (TMB-202)

HIV

Puerto Rico, United States
Genentech, Inc.

Completed

A Study of Retreatment With Rituximab in Patients With Rheumatoid Arthritis Receiving Background Methotrexate (SUNRISE)

Rheumatoid Arthritis
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma

Neuroblastoma

United States, Canada
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody, Paclitaxel, and Interferon Alfa in Treating Patients With Recurrent Ovarian Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer

United States
Genentech, Inc.

Completed

A Study of the Effects of RoActemra/Actemra on Vaccination in Patients With Rheumatoid Arthritis on Background Methotrexate (VISARA)

Rheumatoid Arthritis

United States
Bristol-Myers Squibb

Completed

Study of Abatacept (BMS-188667) in Subjects With Active Rheumatoid Arthritis on Background Non-biologic DMARDS (Disease Modifying Antirheumatic Drugs) Who Have an Inadequate Response to Anti-TNF Therapy

Rheumatoid Arthritis

Belgium, Spain, United States, Germany, Italy, Mexico, United Kingdom, France, Czech Republic, Ireland
NYU Langone Health
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Advanced Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition

United States
Bristol-Myers Squibb

Completed

Multiple Ascending Dose Study of BMS-582949 in Patients With Stable Rheumatoid Arthritis on the Methotrexate Background

Rheumatoid Arthritis

United States, Mexico
Medical University of South Carolina

Not yet recruiting

Study of Fingolimod

Non Small Cell Lung Cancer | Small-cell Lung Cancer
Rockefeller University
Cornell University

Not yet recruiting

Thermogenic Silencer Regulatory Factors in Humans

Obesity | Metabolic Disease | Cold Exposure
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of BL-M07D1+PD-1 Monoclonal Antibody and BL-M07D1+PD-1 Monoclonal Antibody+Capecitabine in Patients With Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma

HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma

China
Odense University Hospital

Recruiting

Long Term Effect of AIT in Children

Allergy in Children

Denmark
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Induction Chemoimmunotherapy Combined With Chemoradiotherapy in Esophageal Cancer

Esophageal Cancer | Surgery | Immunotherapy | Chemoradiotherapy | Induction Therapy

China
University of Leipzig
Rhythm Pharmaceuticals, Inc.

Recruiting

INDIcators for Clarifying the bAckground of exTreme Obesity in childRen (INDICATOR)

Child Obesity | Hunger | Gene Abnormality

Germany
Yanyan Liu

Recruiting

Linperlisib Combined With Chidamide in Patients With PTCL

Peripheral T-cell Lymphoma

China
British University In Egypt

Not yet recruiting

Efficacy of Thyme Honey in The Management of Oral Aphthous Ulcers

Treatment Compliance | Aphthous Stomatitis (Major) (Minor)

Egypt
Pfizer

Not yet recruiting

A Study to Understand How Effective is Tofacitinib When Compared to Other Advanced Treatments in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis
Peter MacCallum Cancer Centre, Australia
AbbVie

Not yet recruiting

MRD-Directed Consolidation With Epcor-only or Epcor-R2 Post Anti-CD19 CAR TCell Therapy for Large B-Cell Lymphoma (EpLCART)

Relapsed/Refractory Large B-cell Lymphoma

Australia
Acepodia Biotech, Inc.

Not yet recruiting

ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)

Metastatic Solid Tumor | Locally Advanced Solid Tumor

United States
XRWorkout, Inc
University of Mississippi Medical Center

Recruiting

VR Exercise Intervention in a Workplace Setting (VRW)

Physical Inactivity | Work-Related Stress | Psychological Well-Being

United States
Centre Hospitalier Universitaire de Nīmes

Not yet recruiting

Identification of Limiting Factors in the Locomotor Activity of Individuals With Lower Limb Amputation: (AMPUTEEFACT)

Lower Limb Amputation

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