Search clinical trials for: Blood donor

Total 110384 results

Duke University
University of Pennsylvania; National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes (PROMISE)

Lung Transplant Rejection | Lung Transplant Failure | Lung Transplant; Complications | Lung Transplant; Infection or Inflammation
Sidney Kimmel Comprehensive Cancer Center at Johns...
Janssen Research & Development, LLC

Not yet recruiting

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Lymphoma | Multiple Myeloma | Hodgkin Lymphoma | Myelofibrosis | Non Hodgkin Lymphoma | Chronic Myeloid Leukemia | Hematologic Malignancy | Aplastic Anemia | Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML) | Bone Marrow Transplant Rejection | Acute Lymphoblastic Leukemia (ALL), Adult
Peking University People's Hospital

Not yet recruiting

Kinectics of Donor-specific Anti-HLA Antibody After HLA-incompatible Allogeneic Haematopoietic Stem Cell Transplantation

Haematological Malignancy
Nutricia Foundation

Recruiting

Is Feeding During Therapeutic Hypothermia Safe and Can Improve Outcomes in Infants With Hypoxic-ischaemic Encephalopathy

Newborn Asphyxia

Poland
Ciusss de L'Est de l'Île de Montréal

Recruiting

Donor-Derived EBV-Specific T Cells for Life Threatening EBV-lymphoma (OLIP-EBV-TCL-01-HMR01)

EBV Associated Lymphoma

Canada
Catharina Ziekenhuis Eindhoven
Maastricht University

Not yet recruiting

The Contractile Response of the Thoracic Aorta to Vasoactive Substances (AorticContract)

Human Thoracic Aorta Contractility

Netherlands
Children's National Research Institute
The Hospital for Sick Children; Ann & Robert H Lurie Children's Hospital of... and other collaborators

Recruiting

Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell AntibodY (SUN-RAY)

Sickle Cell Disease

United States
Suping ZHANG

Recruiting

Blinatumomab for Relapsed Acute B Lymphoblastic Leukemia After Transplantation

Acute B-cell Lymphoblastic Leukemia

China
Beijing GoBroad Hospital

Recruiting

Optimised CD33 (FL-33) CAR T Therapy for Refractory/Relapsed Acute Myeloid Leukaemia

Refractory/Relapsed Acute Myeloid Leukaemia

China
Beijing GoBroad Hospital

Not yet recruiting

Safety, Tolerability, and Pharmacokinetics of Donor-derived CD19 CAR Therapy Bridged Allo-HSCT and Sequential Donor-derived CD22 CAR Therapy for r/r B-ALL: a Clinical Trial

Acute Lymphoblastic Leukemia, in Relapse | B-cell Acute Lymphoblastic Leukemia
Beijing GoBroad Hospital

Not yet recruiting

CD5 Chimeric Antigen Receptor (CAR) T Cells in Subjects With Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia, in Relapse | Refractory Acute Lymphoblastic Leukemia | T-Cell Acute Lymphocytic Leukemia
Beijing GoBroad Hospital

Recruiting

Autologous and Donor-derived CD7 CAR-T Therapy in Refractory or Relapsed T-cell Acute Lymphoblastic Leukemia/Lymphoma

Acute Lymphoblastic Leukemia, in Relapse | Refractory Acute Lymphoblastic Leukemia | T-cell Acute Lymphoblastic Leukemia

China
M.D. Anderson Cancer Center
Astex Pharmaceuticals, Inc.

Not yet recruiting

A Phase I/II Trial to Assess the Efficacy and Toxicity of ASTX727 (Oral Decitabine/Cedazuridine) for the Treatment of Hematological Neoplasms After Allogeneic Stem Cell Transplantation

Allogeneic Stem Cell Transplantation

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
Nantes University Hospital

Not yet recruiting

Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation (CY-MET-RIC)

Hematologic Malignancy | Graft Versus Host Disease
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Upfront Related Donor Transplantation in Patients With Myelodisplatic Syndrome : a Phase 2 Trial (FIRST ALLO MDS)

Myelodysplastic Syndromes
Heart Center Research, LLC
Boston Scientific Corporation

Recruiting

Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts (DART-HA)

Heart Failure, Congestive

United States
Elvira Umyarova
Sanofi

Recruiting

Donor Immune Cells (TGFbi NK Cells) and Isatuximab for the Treatment of Relapsed or Refractory Multiple Myeloma

Refractory Multiple Myeloma | Recurrent Multiple Myeloma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
Centre Hospitalier Universitaire Dijon

Recruiting

Lipid Characterisation of Plasma Microparticles in a Large Population of Healthy Donors (MicroLipids)

Healthy Donor

France
Buddhist Tzu Chi General Hospital

Not yet recruiting

The Effects of Jing Si Herbal Tea on Physical and Psychological Symptoms in Peripheral Blood Hematopoietic Stem Cell Donors

Emotional Stress | Pain Syndrome
Nationwide Children's Hospital

Recruiting

αβT Cell/CD19+ B Cell Depletion for Alternative Donor Allogeneic Hematopoietic Cell Transplantation (HSCT) (TB19DHCT)

Hematologic Malignancy | Hematopoietic Stem Cell Transplantation

United States
Peking University People's Hospital

Recruiting

The Optimization of Conditioning Regimen for HLA Matched HSCT in SAA

Severe Aplastic Anemia

China
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

Acute Myeloid Leukemia | Hodgkin Lymphoma | Myelofibrosis | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Hematopoietic and Lymphoid System Neoplasm | Myeloproliferative Neoplasm | Chronic Myeloid Leukemia, BCR-ABL1 Positive

United States
Hospices Civils de Lyon

Not yet recruiting

Multi-parametric MRI Evaluation of Renal Graft Performance After Living Donor Donation. (DOVIMIR)

Renal Insufficiency, Chronic
Assistance Publique - Hôpitaux de Paris
Etablissement Français du Sang (Nouvelle Aquitaine)

Recruiting

Obstetrical History and Anti-HLA Antibodies Level (OBS-HLA)

Blood Donors | Anti-HLA Antibody

France
Hospices Civils de Lyon

Not yet recruiting

Prevention of Vasovagal Reactions in First-time Blood Donors Using a Combined PSYchological and Physiological Approach (PREDONPSY)

Vasovagal Reaction

France
Center for International Blood and Marrow Transplant...
National Marrow Donor Program

Recruiting

HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis (OPTIMIZE)

Lymphoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myelofibrosis | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Acute Leukemia | Myeloproliferative Neoplasm | Pro-Lymphocytic Leukemia

United States
Vor Biopharma

Recruiting

Donor-Derived Anti-CD33 CAR T Cell Therapy (VCAR33) in Patients With Relapsed or Refractory AML After Allogeneic Hematopoietic Cell Transplant

Leukemia, Myeloid, Acute

United States
University of Minnesota
National Heart, Lung, and Blood Institute (NHLBI); Syracuse University; Liverpool... and other collaborators

Recruiting

Community-based Communication for Blood Donation in Ghana (C-CAD)

Increase Repeat Blood Donation Attempts Among First-time Donors

United States
University Hospital Tuebingen

Recruiting

CD45RA Depleted DLI After TCRα/β Depleted Haploidentical HCT (CD45RADLIHaplo)

Hematologic Malignancy

Germany
Nicox Ophthalmics, Inc.

Recruiting

Aqueous Humor Dynamics of NCX 470 Ophthalmic Solution (Whistler)

Open Angle Glaucoma

United States
Children's Hospital Los Angeles

Not yet recruiting

Iron Deficiency Anemia (IDA) (IDA)

Anemia | Iron Deficiency Anemia | Anemia, Iron Deficiency | IDA - Iron Deficiency Anemia

United States
New York Medical College

Recruiting

Chemoreflex and Baroreflex Alterations Causing Postural Tachycardia Syndrome With Orthostatic Hyperpnea and Hypocapnia

Hyperventilation | Postural Orthostatic Tachycardia Syndrome | Hypocapnia

United States
University of Copenhagen
Clinical Immunological Department, Rigshospitalet; The Danish Blood Donor Study

Recruiting

Characterization of Natural IL-6 Inhibition in Healthy Individuals (FIDI)

Autoantibodies | Interleukin-6

Denmark
San Camillo Hospital, Rome
Azienda Ospedaliero Universitaria, Santa Maria della Misericordia di Udine...

Recruiting

Predictive Value of Vasodilator Challenge for Right Heart Failure After LVAD Implantation (PREVV-RHF-LVAD)

Right Heart Failure

Italy
University of Alberta
Natera, Inc.; One Lambda

Recruiting

Trifecta-Lung cfDNA-MMDx Study

Lung Transplantation

Canada, Australia, Austria, Czechia
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Blood Salvage From Liver Donors: a Feasibility Pilot Study (BLEED)

Liver Transplantation | Erythrocyte Transfusion

Italy
Sanjay Mohan
National Comprehensive Cancer Network; Taiho Oncology, Inc.

Recruiting

Decitabine and Cedazuridine in Combination With Venetoclax for the Treatment of Patients Who Have Relapsed Acute Myeloid Leukemia After Donor Stem Cell Transplant

Recurrent Acute Myeloid Leukemia

United States
Karolinska University Hospital
Nordic MDS Group

Recruiting

A Study Using Subject-specific MRD to Adopt Treatment After HSCT for Subjects With MDS

Myelodysplastic Syndromes | Acute Myeloid Leukemia With Myelodysplasia Related Disease and < 30% Blasts | Mixed Myelodysplastic/Myeloproliferative Disease

Sweden
University of Texas Southwestern Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Multicomponent Intervention Study- Blood Donors With High Cholesterol (DONATE-FH)

Lipid Metabolism Disorder

United States
University Hospital, Basel, Switzerland

Not yet recruiting

EBV-Tscm Cytotoxic T Cells (CTLs) for EBV- Driven Lymphomas/ Diseases (ESPECT)

EBV Lymphoma | Post-transplant Lymphoproliferative Disease (PTLD)

Switzerland
Simon Fraser University
University of British Columbia

Not yet recruiting

NO AD: Use of Nitric Oxide (NO) Donors for the Prevention of Autonomic Dysreflexia (AD) During Bowel Care Following SCI (NO AD)

Spinal Cord Injuries | Autonomic Dysreflexia
The Cleveland Clinic
National Institutes of Health (NIH)

Recruiting

Normal Donor Blood Draws for Platelet Studies and Biomarker Evaluation (ND-PLT) (ND-PLT)

Healthy

United States
University of Edinburgh
Travere Therapeutics, Inc.

Recruiting

ETA and AT1 Antagonism in ANCA-vasculitis (SPARVASC) (SPARVASC)

Cardiovascular Diseases | Kidney Diseases | ANCA Associated Vasculitis

United Kingdom
Hospital Clinic of Barcelona
Institut d'Investigacions Biomèdiques August Pi i Sunyer; Banc de Sang i Teixits

Not yet recruiting

Red Blood Cells From Umbilical Cord for Transfusion of Preterm Infants

Infant, Extremely Premature | Erythrocyte Transfusion | Umbilical Cord Issue
National Institute of Allergy and Infectious Diseases...

Recruiting

Study to Assess the Use of JSP191 in Matched Unrelated Donor Transplantation for Chronic Granulomatous Disease (CGD)

Chronic Granulomatous Disease | CGD

United States
Boston Children's Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Recruiting

A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202) (TransIT)

Severe Aplastic Anemia

United States
Ossium Health, Inc.
Center for International Blood and Marrow Transplant Research

Recruiting

A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Acute Leukemia | Acute Undifferentiated Leukemia | Acute Biphenotypic Leukemia

United States
University Health Network, Toronto

Recruiting

A2 to O Lung Transplants

Lung Transplant | ABO Incompatibility

Canada

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