The Effects of Jing Si Herbal Tea on Physical and Psychological Symptoms in Peripheral Blood Hematopoietic Stem Cell Donors

This study aim to explore the impact of Jing Si Herbal Tea on pain and emotional stress in peripheral blood stem cell donors.

Study Overview

• Status: Enrolling by invitation
• Conditions: Emotional Stress; Pain Syndrome
• Intervention / Treatment: Other: Jing Si Herbal Drink

• Study Type: Interventional
• Enrollment (Estimated): 80
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Taiwan
  • Hualien City, Taiwan, 970
    • Hualiien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• health Men or women aged 20 to 55 years old
• willing to take Jing Si Herbal Drink

Exclusion Criteria:

• no willing to take Jing Si Herbal Drink;
• Previously already take Jing Si Herbal Drink daily

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Supportive Care
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Other: NORMAL; daily diet	Other: Jing Si Herbal Drink; Jing Si Herbal Drink
No Intervention: Take Jing Si Herbal Drink; Take Jing Si Herbal Drink daily

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Changes in pain assessed by questionnaires	For each of the pain sites includes: headache、bone、joint & muscle, indicate the severity of present using the following scale (baseline vs. follow-up). grade 0: fully active, able to carry on all pre-disease performance without restriction grade 1: restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g. light housework, office work grade 2: ambulatory and capable of all self-care but unable to carry out any work activities, up and about more than 50% of waking hours grade 3: capable of only limited self-care, confined to bed or chair more than 50% of waking hours grade 4: completely disabled, cannot carry on any self-care, totally confined to bed or chair grade 5: dead	5 day

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Changes in anxiety assessed by questionnaires	Difference in donor Health State Trait Anxiety Index (STAI) scores (baseline vs. follow-up). The STAI questionnaire consists of 20 items for assessing "state anxiety" and 20 items for assessing "trait anxiety," with a raw score of 20 to 60 points for each scale. The state anxiety scale evaluates the current state of anxiety associated with a special situation, measuring subjective feelings of apprehension, tension, nervousness, worry, and activation of the autonomic nervous system, whereas the trait anxiety scale evaluates proneness to anxiety . The level of anxiety was determined according to the percentile rank obtained using the raw score of each questionnaire and was classified as low anxiety (1st-23th percentile), moderate anxiety (25th75th percentile) and high anxiety (77th-99th percentile).	21 days

Collaborators and Investigators

• Sponsor: Buddhist Tzu Chi General Hospital

Study record dates

Study Major Dates

• Study Start (Estimated): September 18, 2025
• Primary Completion (Estimated): December 31, 2027
• Study Completion (Estimated): December 31, 2027

Study Registration Dates

• First Submitted: November 5, 2023
• First Submitted That Met QC Criteria: November 15, 2023
• First Posted (Actual): November 21, 2023

Study Record Updates

• Last Update Posted (Estimated): September 19, 2025
• Last Update Submitted That Met QC Criteria: September 15, 2025
• Last Verified: October 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Mental Disorders; Behavioral Symptoms; Behavior; Somatoform Disorders; Stress, Psychological
• Other Study ID Numbers: IRB111-125-A; IMAR-111-01-17 (Other Grant/Funding Number: BuddhistTCGH)

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No