Search clinical trials for: CYP 2C19

Total 7343 results

Università degli Studi di Ferrara

Unknown

Effect of Proton Pump Inhibitor on Residual Platelet Reactivity After Clopidogrel in Homogenous Genetic Strata (GENIOUS)

Coronary Stenting

Italy
Eisai Co., Ltd.

Terminated

A Study of E7070 in Patients With Gastric Cancer

Gastric Cancer

Japan
Gyeongsang National University Hospital

Completed

Adjunctive Cilostazol Versus High Maintenance-dose Clopidogrel According to Cytochrome 2C19 Polymorphism (ACCEL-2C19)

Coronary Artery Disease | Percutaneous Coronary Intervention

Korea, Republic of
University Hospital, Geneva

Recruiting

Risk of CYP2C19 Phenoconversion in Healthy Volunteers With Rapid, Normal, and Intermediate Predicted Metabolizers' Status (Switch19)

Healthy

Switzerland
Gangnam Severance Hospital
SAMJIN PHARM

Completed

Clopidogrel Preventive Effect Based on CYP2C19 Genotype in Ischemic Stroke

Acute Ischemic Stroke

Korea, Republic of
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

A Study of ARQ 197 in Healthy Volunteers to Assess the Pharmacokinetic (PK) Profile in Extensive and Poor Metabolizers as Defined by Cytochrome P450 2C19 (CYP 2C19) Genotype

Healthy

United States
dingshifang
Shandong Provincial Hospital; Qianfoshan Hospital; Jinan Military General Hospital and other collaborators

Unknown

CYP 2C19 Polymorphism and Voriconazole Trough Concentration in Chinese Adult Patients

Invasive Pulmonary Aspergillosis

China
Gyeongsang National University Hospital

Completed

Adjunctive Cilostazol Versus High Maintenance-dose ClopidogrEL in Acute Myocardial Infarction (AMI) Patients According to CYP2C19 Polymorphism (ACCELAMI2C19)

Myocardial Infarction

Korea, Republic of
University Hospital, Toulouse

Withdrawn

Impact of Genotyping P450 2C19 on Hospitalization Period (PHARMACOGEN)

Infection
Gesche Jurgens
Bispebjerg Hospital; TrygFonden, Denmark; Research Unit, Psyciatric Centre Bispebjerg and other collaborators

Completed

Effect of Genotyping for CYP450 Polymorphisms Versus Intense Clinical Monitoring on Antipsychotic Drug Treatment

Schizophrenia

Denmark
Indiana University
Sponsor Name Pending

Completed

Rapid Screening Phenotype Test To Evaluate CYP 2C19 Enzyme Activity Using Stable Isotope [13C]Pantoprazole

Healthy

United States
Corcept Therapeutics

Completed

Study to Evaluate the Effects of a Cytochrome P450 2C19 Inhibitor on the Pharmacokinetics of Miricorilant

Non-alcoholic Steatohepatitis (NASH) | Antipsychotic Induced Weight Gain

United States
Lancaster General Hospital
Louise von Hess Medical Research Institute; H G Barsumian MD Memorial Fund

Withdrawn

Pharmacodynamic Study on Efficacy of Clopidogrel With St. John's Wort (INDUCE-it)

Acute Coronary Syndrome

United States
Gyeongsang National University Hospital

Unknown

Comparison of Platelet Inhibition With Adjunctive Cilostazol Versus High Maintenance-Dose Clopidogrel According to Hepatic Cytochrome 2C19 Allele (CYP2C19) Polymorphism (ACCEL2C19)

Coronary Artery Stenosis | Maximal Platelet Aggregation | Late Platelet Aggregation | High Post-Treatment Platelet Reactivity

Korea, Republic of
Chinese Academy of Sciences
LanZhou University

Completed

Cytochrome P450 2C19 Variant is Related to Pharmacokinetics of Glipizide Extended Release Tablet in Chinese Subjects

Pharmacokinetic | Genotype

China
Osaka University

Withdrawn

Randomized Trial for Pharmacogenomics-based Proton Pump Inhibitor Therapy in Children

Gastroesophageal Reflux

Japan
Genelex Corporation
Harding University

Completed

Pharmacogenetic Testing Among Home Health Patients

Drug Interaction Potentiation | Adverse Drug Events | Adverse Drug Reactions | Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant | Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 Enzyme... and other conditions

United States
St. Antonius Hospital

Completed

Antiplatelet Therapy for Patients Undergoing Transcatheter Aortic Valve Implantation (POPular-TAVI)

Myocardial Infarction | Stroke | Bleeding | Aortic Valve Disease

Netherlands, Belgium, Czechia, Luxembourg
University of Nicosia

Recruiting

The Effectiveness of Mixed Reality as Interventional Tool for the Improvement on Quality of Life for People With Parkinson´s Disease.

Parkinson Disease

Cyprus
Istituto Scientifico Romagnolo per lo Studio e...
Charite University, Berlin, Germany; University of Bologna; Hannover Medical... and other collaborators

Not yet recruiting

Master Framework For Relapse or Refractory Acute Myeloid Leukemia (IMPACT STREAM)

Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory

Italy
Bradley Nindl
U.S. Army Medical Research and Development Command

Not yet recruiting

Adaptions and Resiliency to Multi-Stressor OpeRations (ARMOR)

Hypogonadism | Musculoskeletal Injury

United States
University of California, San Diego
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Not yet recruiting

Androgen Effects on the Reproductive Neuroendocrine Axis

Reproductive Issues | Transgenderism

United States
Spyre Therapeutics, Inc.
Altasciences Company Inc.

Recruiting

A Study of SPY001-001 in Healthy Volunteers

Healthy

United States, Canada
University of Miami
Medtronic

Not yet recruiting

STARLITE for Unresectable High-Grade Gliomas (STARLITE)

High Grade Glioma

United States
University Hospital, Ghent

Recruiting

Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO) (PADECMO)

Pharmacokinetics | Vancomycin | Amoxicillin-clavulanate | Piperacillin-tazobactam | Teicoplanin | Meropenem | Ciprofloxacin | Amikacin | Cefazolin

Belgium
Xie Kangjie

Recruiting

Study on Pharmacokinetics of Single Injection of Ciprofol in Patients With Moderate to Severe Hypoproteinemia

Pharmacokinetics | Hypoproteinemia | Ciprofol

China
Gaziosmanpasa Research and Education Hospital

Recruiting

Ultrasonographic Measurement of Diaphragmatic Thickness in Adolescents With Thoracal Hyperkyphosis

Spine Deformity | Diaphragm Issues | Hyperkyphosis

Turkey
Kemal Elyeli

Recruiting

The Effect of Mindfulness Intervention Program on Adolescents' Internet Addiction (Mindfulness)

Internet Addiction Disorder | Adolescent Behavior | Mindfulness

Cyprus
AstraZeneca
Parexel

Recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
Duke University

Not yet recruiting

RECOVER-SLEEP: Platform Protocol, Appendix_A (Hypersomnia)

Long COVID | Long COVID-19 | Hypersomnia
Duke University

Not yet recruiting

RECOVER-SLEEP: Platform Protocol

Sleep Disturbance | Long COVID | Long COVID-19 | Hypersomnia
Chulalongkorn University

Not yet recruiting

"Quick-starting" of a Quadriphasic Contraceptive Pills, 1 - 3 mg Estradiol Valerate/ 2 - 3 mg Dienogest VS 20 mcg Ethinylestradiol/75 mcg Gestodene Focusing on Ovulation Inhibition

Ultrasound Finding: Ovulation Inhibition, Ovarian Activities | Cervical Mucus | Serum Hormonal Profile
Ohio State University

Not yet recruiting

Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)

Preterm Birth | Pregnancy, High Risk | Preterm Premature Rupture of Membrane

United States
Pfizer

Not yet recruiting

A Study on 2 Different Combination Tablets of Nirmatrelvir Plus Ritonavir to Compare Them With Marketed Paxlovid in Healthy Participants

Healthy Participants | Biological Availability
Chiesi Farmaceutici S.p.A.

Recruiting

Effect of Erythromycin on the Absorption, Metabolism and Elimination of CHF6001 in Healthy Volunteers

Chronic Obstructive Pulmonary Disease

Bulgaria
Beni-Suef University

Recruiting

Efficacy of Voriconazole Loaded Spanlastics Gel Versus Clotriamazole Cream on Treating Vulvovaginal Candidasis

Treatment of Vagnial Cabdudasis

Egypt
Takeda

Recruiting

A Study of TAK-853 in Adult Participants With Folate Receptor Alpha-Positive Advanced Ovarian Cancer And Other Solid Tumors

Ovarian Cancer | Solid Tumors

Japan
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1, Open-label Study Evaluating the Pharmacokinetics and Drug-drug Interaction of VX-993 in Healthy Adults

Pain

United Kingdom
Tolmar Inc.
ICON plc

Recruiting

A Phase 4 Study to Evaluate Adrenal Function in Hypogonadal Men Treated With JATENZO® for 12 Months

Hypogonadism

United States
Eli Lilly and Company

Recruiting

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Renal Function in Adults Living With Obesity (TRIUMPH-OUTCOMES)

Overweight and Obesity

United States, Australia, Italy, Hungary, Spain, Canada, Germany, Argentina, Belgium, Czechia, Greece, Israel, Austria, Brazil, Mexico, Netherlands, Romania, India, United Kingdom, Slovakia, Poland, Turkey, Puerto Rico, France, Denmark
University of Bern
Swiss National Science Foundation; University of Zimbabwe

Not yet recruiting

The Friendship Bench Plus Trial (FB+)

Major Depressive Disorder | Severe Depressive Episode Without Psychotic Symptoms

Zimbabwe
Fore Biotherapeutics

Recruiting

A Study of the Effects of Food and Cobicistat on Plixorafenib Pharmacokinetics in Healthy Volunteers.

Healthy Volunteer

United States
Modern Biosciences Ltd

Recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
The University of Texas Health Science Center,...

Recruiting

Study of Injectable Naltrexone and Oral Bupropion Among Cigarette Smokers With Schizophrenia

Smoking Cessation

United States
GlaxoSmithKline

Recruiting

Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma

Asthma

United States, Canada, Argentina, Australia, Japan, Korea, Republic of, Taiwan
Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Not yet recruiting

How Often and What Type of Deformity is Detected in All Spine Radiographs?

Scoliosis | Kyphosis | Radiography
Eli Lilly and Company

Recruiting

A Drug-Drug Interaction (DDI) Study of Orforglipron With Carbamazepine in Healthy Participants

Healthy

United States
Teknimed

Recruiting

SPINE BONE CEMENTS OUTCOMES

Vertebral Fracture | Osteoporotic Fractures | Compression Fracture

Spain, France, Portugal, Ukraine
Boehringer Ingelheim

Recruiting

A Study in Healthy Men and Women to Test Whether BI 1569912 Influences the Amount of Repaglinide, Midazolam and Bupropion in the Blood

Healthy

Belgium
Institute of Liver and Biliary Sciences, India

Recruiting

Prevalence of CYP3A5 Polymorphisms in the Donors and ABCB1 Polymorphisms in the Recipients Undergoing Pediatric Liver Transplant and Their Influence on Tacrolimus Levels and Graft Function.

Pediatric Liver Transplant

India

Search clinical trials for: CYP 2C19

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