Search clinical trials for: Calcineurine inhibitor

Total 67789 results

Peking Union Medical College Hospital

Not yet recruiting

Luspatercept Plus CsA vs CsA for the Treatment of Newly Diagnosed Non-Transfusion-Dependent NSAA

Aplastic Anemia

China
Masonic Cancer Center, University of Minnesota

Not yet recruiting

MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

Acquired Pure Red Cell Aplasia | Paroxysmal Nocturnal Hemoglobinuria | Severe Aplastic Anemia | Acquired Amegakaryocytic Thrombocytopenia
Air Force Military Medical University, China
First Affiliated Hospital Xi'an Jiaotong University; Shaanxi Provincial People... and other collaborators

Not yet recruiting

Efficacy and Safety of Tacrolimus in Combination With Ripertamab in the Initial Treatment of Patients With MCD

Minimal Change Disease
Famy Life Sciences, a Viatris Company

Recruiting

A Phase 3 Study to Evaluate the Efficacy and Safety of Pimecrolimus 0.3% Ophthalmic Ointment

Blepharitis

United States
Eyestem Research Pvt. Ltd.

Not yet recruiting

Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.

Eye Diseases | Age-Related Macular Degeneration | Macular Degeneration | Geographic Atrophy | Retinal Disease
Université de Sherbrooke

Recruiting

Cyclosporine and Intense Pulsed Light for Dry Eye in Contact Lens Users (CycliP)

Dry Eye | Contact Lens Complication

Canada
Peking University People's Hospital

Not yet recruiting

Efficacy and Safety of Anti-CD25 rhMAb in the Treatment of Steroid-Refractory cGVHD

cGVHD
ITB-Med LLC

Recruiting

A Dose Escalation Study of TCD601 Compared to ATG in de Novo Renal Transplantation

Kidney Transplantation

Spain, Sweden, Austria
University Hospital, Limoges

Not yet recruiting

Evaluation of the Benefits of Administering Immunosuppressive Drugs as Single Daily Doses Over the First Year After Liver Transplantation (EASY) (EASY)

Liver Transplantation | Immunosuppression

France
Hospital Universitario Dr. Jose E. Gonzalez

Recruiting

Evaluation of Safety & Efficacy for the Prevention of Ocular GVHD With Ophthalmic Tacrolimus vs Cyclosporine in Allo-HSCT

Ocular Graft-versus-host Disease

Mexico
M.D. Anderson Cancer Center
Incyte Corporation

Not yet recruiting

High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With Splenomegaly

Myelofibrosis | Splenomegaly

United States
Fondazione IRCCS Policlinico San Matteo di Pavia

Recruiting

Tacrolimus and Personalized Therapy to Prevent Acute Rejection Episodes

Heart Transplant Failure

Italy
Novaliq GmbH

Recruiting

A Clinical Trial to Evaluate the Corneal Endothelial Health of DED Subjects Treated With Cyclosporine

Dry Eye Disease

United States
University of Alabama at Birmingham

Not yet recruiting

Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant

Myelodysplastic Syndromes | Myeloproliferative Disorders | Acute Leukemia | GVHD,Acute

United States
University Hospital, Grenoble
National Agency for Research on AIDS and Viral Hepatitis (ANRS)

Not yet recruiting

Viral Immunity in Solid Organ Transplant Recipients: Monitoring Of The Response To Hepatitis B Booster Vaccination (VITAMIN)

Liver Transplantation | Kidney Transplantation | HBV

France
Odense University Hospital

Not yet recruiting

Topical Tacrolimus for Breast Cancer-related Lymphedema

Lymphedema

Denmark
University Hospital, Rouen

Not yet recruiting

Screening for Subclinical Antibody Mediated Rejection and Efficacy of Belatacept in the Context of de Novo Donor Specific Antibody After Kidney Transplantation (BELA-M-R) (BELA-M-R)

Kidney Transplant Rejection
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

Expanding Liver Transplant Immunosuppression Minimization Via Everolimus (ELIMINATE)

Liver Transplant

United States
Peking University People's Hospital

Not yet recruiting

Sirolimus+Abatacept+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to Calcineurin Inhibitors

Myelodysplastic Syndromes | Acute Leukemia | Severe Aplastic Anemia
Edward Geissler
Chiesi Pharmaceuticals GmbH

Recruiting

Tacrolimus C:D Ratio Measured in Renal Transplant Recipients Treated With Once-daily Prolonged-release Drugs (TaC:Drop)

Immunosuppression

Germany
University of Alabama at Birmingham

Not yet recruiting

Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant

Myeloproliferative Disorders | Acute Leukemia | Myelodysplastic Syndrome

United States
Virginia G. Kaklamani

Not yet recruiting

Breast/Cyclosporin A/TNBC (Triple Negative Breast Cancer)

Triple Negative Breast Cancer | DNA Damage Repair Deficiency

United States
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor (AQUA)

Dermatitis Atopic

Chile, United Kingdom, United States, Canada, Turkey, Israel, Korea, Republic of
Nantes University Hospital

Not yet recruiting

Tacrolimus Minimization in Kidney Transplant Recipients Selected According to the AGORA Algorithm for Their Low Immunological Risk and Medium-term Graft Failure (AGORAC)

Organ Grafts

Norway, Spain, France
Lipella Pharmaceuticals, Inc.

Not yet recruiting

Evaluating LP-10 in Subjects With OLP

Oral Lichen Planus
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis on Background Topical Corticosteroids (SHORE)

Dermatitis Atopic

Japan, Chile, Canada, Argentina, United States, Turkey, China
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
RenJi Hospital

Not yet recruiting

Prospective, Multicenter Clinical Study of Prolonged-release Tacrolimus in Stable Pediatric Liver Transplant Recipients

Liver Transplant

China
Jun Wang

Recruiting

Thymosin Alpha-1 for irAE Secondary to ICIs

IrAE

China
Wei Gao

Not yet recruiting

Efficacy and Safety of Immunosuppressive Withdrawal After Pediatric Liver Transplantation

Liver Transplant; Complications | Immunosuppression | Immune Tolerance

China
Beijing Tsinghua Chang Gung Hospital

Not yet recruiting

Early Conversion of Prolonged-release Tacrolimus in Liver Transplantation.

Liver Transplantation
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 1)

Dermatitis Atopic

Israel, Chile, Australia, United States, Canada, Korea, Republic of, Taiwan, China
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
National University Hospital, Singapore
Agency for Science, Technology and Research

Recruiting

Real-time Early Detection of Nephrotoxicity by Urinary Biomarker Analysis With SeroFlow Technology (RenaFAST)

Acute Kidney Injury

Singapore
Case Comprehensive Cancer Center

Not yet recruiting

Intestinal & Multivisceral Transplantation for Unresectable Mucinous Carcinoma Peritonei (TRANSCAPE) (TRANSCAPE)

Pseudomyxoma Peritonei | Secondary Malignant Neoplasm of Peritoneum | Secondary Malignant Neoplasm of Retroperitoneum

United States
University of Pisa

Recruiting

Tacrolimus Blood Concentration and Transplant-related Outcomes in Pediatric HSCT Recipients

Graft Vs Host Disease | Stem Cell Transplant Complications | Transplant Failure

Italy
University Hospital, Essen

Recruiting

Pharmacokinetics, Effectiveness and Tolerability of Prolonged-release Tacrolimus After Paediatric Kidney Transplantation (Pro-Tac)

Pediatric Kidney Disease

Germany
National Institute of Allergy and Infectious Diseases...

Recruiting

Advancing Transplantation Outcomes in Children (ADVANTage)

Kidney Transplant

United States
MEDA PHARMA SPA, a Viatris company

Not yet recruiting

Observational Study to Evaluate Use of Elidel® in South and East Asian Pediatric Patients With Atopic Dermatitis. (Elidel-SEA)

Mild to Moderate Atopic Dermatitis
Peking University Third Hospital

Recruiting

The Effect of 0.05% CsA Eye Drops on Post-refractive Surgery Dry Eye

Dry Eye

China
ITB-Med LLC

Recruiting

A Study of TCD601 in the Induction of Tolerance in de Novo Liver Transplantation

Liver Transplantation

Sweden
Fred Hutchinson Cancer Center
National Cord Blood Network

Recruiting

Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Hematopoietic and Lymphoid System Neoplasm | Blastic Plasmacytoid Dendritic Cell Neoplasm | Myeloproliferative Neoplasm | Acute Leukemia of Ambiguous Lineage | Mixed Phenotype Acute Leukemia | Chronic...

United States
Peking Union Medical College Hospital

Not yet recruiting

Romiplostim in Combination With CsA vs. CsA in the Treatment of Newly Diagnosed NSAA

Non Severe Aplastic Anemia

China
Peking Union Medical College Hospital

Recruiting

Efficacy and Safety of CsA+AVA in the Treatment of NSAA in the Elderly

Aplastic Anemia

China
Center for International Blood and Marrow Transplant...
National Marrow Donor Program

Recruiting

HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis (OPTIMIZE)

Lymphoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myelofibrosis | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Acute Leukemia | Myeloproliferative Neoplasm | Pro-Lymphocytic Leukemia

United States
Peking Union Medical College Hospital

Not yet recruiting

CsA+ATG+AVA vs. CsA+AVA for the Treatment of Newly-diagnosed SAA in the Elderly

Aplastic Anemia

China
Eledon Pharmaceuticals

Recruiting

Safety and Efficacy of Tegoprubart in Patients Undergoing Kidney Transplantation

Kidney Transplant Rejection

United States, Spain, Australia, Germany, France, Brazil
Aurinia Pharmaceuticals Inc.
Labcorp Corporation of America Holdings, Inc

Not yet recruiting

Long-Term Voclosporin Treatment in Adolescent Subjects With Lupus Nephritis (VOCAL-EXT)

Adolescent Lupus Nephritis

United States
University of Waterloo
Sun Pharmaceutical Industries Limited

Recruiting

Improving Drop Instillation Comfort of a Cyclosporine A Solution

Dry Eye Disease

Canada

Search clinical trials for: Calcineurine inhibitor

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