Search clinical trials for: Diabetic macular edema, DME, ranibizumab, wait and extend

Total 472784 results

Novartis Pharmaceuticals

Completed

Compare Safety/Efficacy of Labeled vs Wait-Extend Regimen of Lucentis in Turkish Patients With VI Due to DME (SALUTE-D)

Diabetic Macular Edema

Turkey
McMaster University
Hoffmann-La Roche

Recruiting

Treat & Extend Versus Fixed Dosing With Faricimab for Management of Diabetic Macular Edema: A Pragmatic, Multi-center, Open-label, Randomized, Controlled Trial (INSITE-DME)

Diabetic Macular Edema

Australia, United States, Canada, United Kingdom
Palmetto Retina Center, LLC

Completed

A Safety and Efficacy Trial of a Treat and Extend Protocol Using Ranibizumab With and Without Laser Photocoagulation for Diabetic Macular Edema (TREX-DME)

Diabetic Macular Edema

United States
Taipei Veterans General Hospital, Taiwan
National Taiwan University Hospital; Chang Gung Memorial Hospital; Kaohsiung...

Completed

Efficacy and Safety of Aflibercept as Mono-therapy in Treat and Extend Regimen for DME Patients in Taiwan

Center-involved Diabetic Macular Edema
Novartis Pharmaceuticals

Completed

An Open-label Extended Clinical Protocol of Ranibizumab to Evaluate Safety and Efficacy in Rare VEGF Driven Ocular Diseases. (ECLIPSE)

Diabetic Retinopathy | Macular Edema | Choroidal Neovascularization | Glaucoma, Neovascular

France
Pusan National University Hospital
Novartis

Unknown

Treat-and-extend Regimen of Aflibercept in Diabetic Macular Edema (VIBIM Study) (VIBIM)

Macular Edema, Diabetic

Korea, Republic of
Hadassah Medical Organization
Bayer

Completed

Multicenter Study to Evaluate the Efficacy of Treat and Extend Regimen of Aflibercept (EYLEA) as a Second Line Treatment for Diabetic Macular Edema

Diabetic Macular Edema (DME)
Novartis Pharmaceuticals

Completed

Ranibizumab "Treat and Extend" in Diabetic Macular Edma (OPTIMAL)

Diabetic Macular Edema

Norway
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab in Two "Treat and Extend" Treatment Algorithms Versus Ranibizumab As Needed in Patients With Macular Edema and Visual Impairment Secondary to Diabetes Mellitus (RETAIN)

Diabetic Macular Edema

Belgium, United Kingdom, Netherlands, Ireland, Switzerland, Italy, Hungary, France, Spain, Portugal, Poland, Czech Republic, Greece
Hoffmann-La Roche
Shanghai Roche Pharmaceutical Co., Ltd

Recruiting

Real World Evidence in China: Faricimab Use in Diabetic Macular Edema, Retinal Vein Occlusion, and Neovascular Age-Related Macular Degeneration (The Farseeing Study)

Diabetic Macular Edema | Retinal Vein Occlusion | Neovascular Age-related Macular Degeneration

China
Bayer
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Learn More About How Well 8 Milligram Aflibercept Works and How Safe it is in Chinese Participants With Diabetic Macular Edema (PHOTONiC)

Diabetic Macular Edema
Zhejiang University

Not yet recruiting

Comparing Artificial Intelligence for Assisted Diagnosis of Diabetic Retinopathy

Diabetic Retinopathy | Diabetic Macular Edema

China
Regeneron Pharmaceuticals

Not yet recruiting

An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting (SPECTRUM-US)

Visual Impairment | Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (nAMD) | Wet Age-related Macular Degeneration (AMD)
Eli Lilly and Company

Recruiting

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Renal Function in Adults Living With Obesity (TRIUMPH-OUTCOMES)

Overweight and Obesity

United States, Australia, Italy, Hungary, Spain, Canada, Germany, Argentina, Belgium, Czechia, Greece, Israel, Austria, Brazil, Mexico, Netherlands, Romania, India, United Kingdom, Slovakia, Poland, Turkey, Puerto Rico, France, Denmark
IRCCS Multimedica
AbbVie

Recruiting

OCT and OCT-Angiography Biomarkers of Treatment Response to Dexamethasone Implant in Macular Edema Due to Retinal Vascular Diseases - DME and RVO

Diabetic Macular Edema | Retinal Vein Occlusion | Macular Edema Due to Diabetes Mellitus

Italy
Rehab Azzam

Not yet recruiting

Outcomes After Vitrectomy in Eyes With Tractional Diabetic Macular Edema

Diabetic Macular Edema
Everads Therapy

Recruiting

Everads Injector in Suprachoroidal Administration of TA Suspension, for Treatment of Patients With DME

Diabetic Macular Edema

Israel
Shanghai Eye Disease Prevention and Treatment Center
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Recruiting

Efficacy and Safety of Conbercept for Diabetic Macular Edema Combined With Severe Non-proliferative Diabetic Retinopathy

Diabetic Macular Edema

China
Incepta Pharmaceuticals Ltd
Institute for Developing Science and Health Initiatives, Bangladesh

Recruiting

A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema

Macular Degeneration | Retinal Degeneration | Diabetic Retinopathy | Diabetic Macular Edema | Macular Edema | Retinal Disease

Bangladesh
Zhongshan Ophthalmic Center, Sun Yat-sen University

Not yet recruiting

Exploring the Interaction Between Metabolic Disorders and NLPR3 Inflammasome Activation in DR Inflammatory Damage (DR)

Diabetic Retinopathy | Diabetic Macular Edema | Anti-vascular Endothelial Growth Factor

China
Kodiak Sciences Inc

Recruiting

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR) (GLOW2)

Non-proliferative Diabetic Retinopathy

United States, Puerto Rico
Ain Shams University

Recruiting

Effect of PPV+ILM Peeling +/- Subretinal Injection of Ringer Lactate in Management of Nontractional Refractory DME

Efficacy | Safety

Egypt
University Hospital, Clermont-Ferrand

Recruiting

Single-center Study Measuring OSDI Dry Eye Score in Patients Undergoing an Anti-VEGF Induction Protocol (PISO)

Macular Degeneration | Diabetic Macular Edema | Retinal Vein Occlusion

France
The University of Texas Health Science Center at...
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes

Type 2 Diabetes (Adult Onset)

United States
Wang Min
Lanyue Biotech (Hangzhou) Co., Ltd.

Recruiting

A Clinical Study Evaluating the Safety, Tolerability and Initial Efficacy of SKG0106 Intravitreal Injection in Diabetic Macular Edema (DME) Patients

Diabetic Macular Edema

China
Sohag University

Recruiting

Relationship Between Dyslipidemia and The Response of Diabetic Macular Edema to Intravitreal Injection of Anti Vascular Endothelial Growth Factor Agents

Diabetic Macular Edema

Egypt
Digital Diagnostics, Inc.

Recruiting

Assessment of Retinal Fundus Imaging Camera

Diabetic Retinopathy | Diabetic Macular Edema

United States
Oculis
ICON plc

Recruiting

Study of the Efficacy and Safety of OCS-01 Eye Drops in Subjects With Diabetic Macular Edema (DIAMOND-2)

Diabetic Macular Edema

United States
Kyowa Kirin, Inc.

Recruiting

Study to Assess the Efficacy & Safety of KHK4951 in Patients With Diabetic Macular Edema

Diabetic Macular Edema (DME)

Australia, United States, Japan, Korea, Republic of
EyePoint Pharmaceuticals, Inc.

Not yet recruiting

Study of EYP-1901 in Patients With Diabetic Macular Edema (DME) (VERONA)

Diabetic Macular Edema
Zhongshan Ophthalmic Center, Sun Yat-sen University

Not yet recruiting

Evaluation of New Head-mounted Visual Aids Among Patients With Low Vision

Glaucoma | Diabetic Retinopathy | Age-related Macular Degeneration | Retinitis Pigmentosa

China
Johannes Kepler University of Linz

Recruiting

Diagnostic Possibilities in Ophthalmological Diseases Using Swept Source Optical Coherence Tomography

Macular Degeneration | Diabetic Retinopathy | Retinal Disease

Austria
Bayer

Recruiting

The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema

Visual Impairment | Neovascular Age-related Macular Degeneration (nAMD) | Diabetic Macula Edema (DME)

Germany, Canada, Denmark, France, Italy, Saudi Arabia, Switzerland, Australia, Finland, Netherlands, Sweden, Norway, United Arab Emirates, Japan, United Kingdom
Unity Biotechnology, Inc.

Recruiting

Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE) (ASPIRE)

Eye Diseases | Diabetes Mellitus | Retinal Degeneration | Retinal Diseases | Edema | Diabetic Retinopathy | Diabetic Macular Edema | Macular Edema | Retinal Disease

United States
Tianjin Medical University Eye Hospital
Abbvie Pharmaceutical Trading (Shanghai) Co., Ltd.

Recruiting

Compare the Efficacy of VItrectomy Combined With DExamethasone Implant Versus With Aflibercept in DME Patients Diagnosed by Intraoperative OCT (the VIDEO Study): Study Protocol for a Randomized Controlled Trial

Diabetic Macular Edema | Pars Plana Vitrectomy | Dexamethasone Intravitreal Implant | Intraoperative Optical Coherence Tomography

China
AbbVie

Recruiting

Observational Study of Adult Participants With Diabetic Macular Edema and Suboptimal Response to Anti-Vascular Endothelial Growth Factor Treated With Dexamethasone Intravitreal Implant

Diabetic Macular Edema

Greece, Portugal, Belgium, United Kingdom, Italy, Israel, China, Germany
Novartis Pharmaceuticals

Not yet recruiting

Post Marketing Study to Evaluate the Safety and Effectiveness of Brolucizumab in Patients With Diabetic Macular Edema.

Diabetic Macular Edema
AskGene Pharma, Inc.
Suzhou Aosaikang Biopharmaceutical Co., Ltd.

Not yet recruiting

A Study of ASKG712 in Patients With Diabetic Macular Edema

Diabetic Macular Edema

China
4D Molecular Therapeutics

Recruiting

4D-150 in Patients With Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

United States, Puerto Rico
EyeBiotech Ltd.

Recruiting

A 2-part Study Consisting of Multiple Ascending Dose (MAD) Safety Study, and a Dose-finding Masked Study to Assess the Safety and Efficacy of Intravitreal (IVT) EYE103 in Patients With Diabetic Macular Edema (DME) or Neovascular Age-related Macular Degeneration (NVAMD) (AMARONE)

Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (NVAMD)

United States, Argentina, Puerto Rico, United Kingdom
Frontera Therapeutics
Peking Union Medical College Hospital; The First Affiliated Hospital of Zhengzhou... and other collaborators

Recruiting

Gene Therapy for Diabetic Macular Edema

Diabetic Macular Edema

China
Jaeb Center for Health Research
Juvenile Diabetes Research Foundation; National Eye Institute (NEI); National...

Recruiting

Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD (AO)

Neovascular Age-related Macular Degeneration

United States
RemeGen Co., Ltd.

Recruiting

Efficacy and Safety of RC28-E Versus Aflibercept in Diabetic Macular Edema

Diabetic Macular Edema

China
Ain Shams University

Recruiting

Comparative Study Between IVI of Ranibizumab With and Without Prior ACP in Patients With DME Using OCT-A

Diabetic Macular Edema

Egypt
Ocugen

Not yet recruiting

Phase I Study to Assess the Safety and Efficacy of OCU200 for Center-Involved Diabetic Macular Edema (DME) (DME)

Diabetic Macular Edema | Center Involved Diabetic Macular Edema
The Netherlands Cancer Institute
Catharina Ziekenhuis Eindhoven; ZonMw: The Netherlands Organisation for Health...

Recruiting

Organ Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local Excision (OPAXX)

Quality of Life | Rectal Cancer | Organ Preservation | Locally Advanced Rectal Carcinoma

Netherlands
Evolucare Technologies
Assistance Publique - Hôpitaux de Paris; Slb Pharma; BPIfrance

Recruiting

OphtAI Diagnostic Performance Validation for Automated Screening of Eye Diseases (OPHTAI-EVAL)

Glaucoma | Age-Related Macular Degeneration | Diabetic Retinopathy | Diabetic Macular Edema | Age-related Maculopathy

France
Notal Vision Inc.

Recruiting

Evaluation of Repeated, In-Clinic, Self-Imaging by DME Patients Using the Notal Vision Home OCT

Diabetic Macular Edema

United States
Tianjin Medical University Eye Hospital

Recruiting

Microinvasive Pars Plana Vitrectomy Combined ILM Peeling Versus Anti-VEGF Intravitreal Injection for Treatment-naïve Diabetic Macular Edema

Diabetic Macular Edema | Pars Plana Vitrectomy | Conbercept

China
Jaeb Center for Health Research
Juvenile Diabetes Research Foundation; National Eye Institute (NEI); National...

Recruiting

Evaluation of Tonabersat for DME (AN)

Diabetic Macular Edema

United States

Search clinical trials for: Diabetic macular edema, DME, ranibizumab, wait and extend

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