Search clinical trials for: Drug Targeting

Total 259428 results

Fudan University

Not yet recruiting

QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk TNBC Breast Cancer (QUEEN-Dream)

Neoadjuvant Therapy | Early Breast Cancer | TNBC, Triple Negative Breast Cancer

China
Fudan University

Not yet recruiting

QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk ER+/HER2- Breast Cancer (QUEEN-Neo)

Neoadjuvant Therapy | Early Breast Cancer | HR+HER2- Breast Cancer
Petra Zimmermann
ETH Zurich; University of Luzern

Not yet recruiting

NapBiome: Targeting Gut Microbiota and Sleep Rhythm to Improve Developmental and Behavioral Outcomes in Early Childhood (NapBiome)

Neurobehavioral Manifestations | Sleep Problem

Switzerland
Tianjin Medical University Cancer Institute and...
Nanjing Legend Biotech Co.

Not yet recruiting

Targeting CD19/CD20 Dual-targeted Cell in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

B-Cell Non-Hodgkin Lymphoma-Recurrent | B-Cell Non-Hodgkin Lymphoma-Refractory

China
Wuhan Union Hospital, China

Recruiting

Study on the Clinical Application Value of PET Imaging Targeting GPC3 in Hepatocellular Carcinoma

Malignant Neoplasm of Liver

China
M.D. Anderson Cancer Center

Not yet recruiting

Phase I/II Study of Engineered T Cell Receptor-Modified NK Cells Targeting PRAME in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Myeloid Malignancies

Myeloid Malignancies | Lymphodepleting Chemotherapy

United States
Pyramid Biosciences

Not yet recruiting

A Phase 1/2 Study of PBI-410 in Advanced Solid Tumors

Solid Tumor

United States
University of Kansas Medical Center

Not yet recruiting

Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis.

Cystic Fibrosis

United States
Essen Biotech

Not yet recruiting

Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE) (BAH242)

Autoimmune Diseases | Systemic Lupus Erythematosus | Systemic Sclerosis | Lupus Nephritis | Microscopic Polyangiitis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Sjogren's Syndrome | Idiopathic Inflammatory Myopathies | Granulomatous Polyangiitis

China
UNC Lineberger Comprehensive Cancer Center
Bellicum Pharmaceuticals

Not yet recruiting

Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells

Breast Cancer | Triple Negative Breast Cancer | Relapse | Resistant Cancer

United States
Centre Hospitalier Universitaire de Nice

Recruiting

Vitiligo Treatment by Targeting TYK2 Mediated Responses (ViTYK)

Vitiligo, Generalized

France
Chinese PLA General Hospital

Recruiting

TCR Reserved and Power3 Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B Cell Lymphoma

Non-hodgkin Lymphoma

China
Chinese PLA General Hospital

Recruiting

Allogeneic TRAC Locus-inserted CD19-targeting STAR T Cell Therapy in r/r B-NHL

Non-hodgkin Lymphoma,B Cell

China
LMU Klinikum

Not yet recruiting

Combining Clemastine and Aerobic Exercise to Treat Cognitive Dysfunction in Schizophrenia by Targeting Myelin Plasticity (OligoTreat)

Schizophrenia
UNC Lineberger Comprehensive Cancer Center

Not yet recruiting

Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells

Ovarian Cancer | Epithelial Ovarian Cancer | Ovary Neoplasm | Recurrent

United States
Lebanese University
Haykel Hospital

Recruiting

Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA (PTST_PALBEVA)

Cancer | Breast Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Chemotherapy | Solid Tumor | Immunotherapy | Targeted Therapy | Precision Therapy

Lebanon
Karolinska Institutet
Karolinska University Hospital

Not yet recruiting

Internet-based Behavioral Intervention Following ACS (ACS-CBT)

Acute Coronary Syndrome | Online CBT Targeting Cardiac Anxiety

Sweden
China Medical University Hospital

Not yet recruiting

Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep Apnea

Obstructive Sleep Apnea of Adult
The First Affiliated Hospital with Nanjing Medical...
Nanjing Legend Biotech Co.

Recruiting

Targeting CD19/CD20 Dual-targeted Cell in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

Relapsed and Refractory B-cell Non-Hodgkin Lymphoma

China
Wellbeing Services County of Pirkanmaa
University of Helsinki; Tampere University; Metropolia University of Applied...

Recruiting

Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases (LumoPrevent)

Periodontitis | Dental Caries in Children | Dental Plaque | Tooth Decay

Finland
China Medical University, China
Beijing Bio-Targeting Therapeutics Technology Co., Ltd

Not yet recruiting

A Clinical Study of BioTTT001 in Combination With Toripalimab and Regorafenib in Patients With Colorectal Cancer

Colorectal Cancer Metastatic
China Medical University, China
Beijing Bio-Targeting Therapeutics Technology Co., Ltd

Not yet recruiting

A Clinical Study of BioTTT001 in Combination With SOX and Toripalimab in Patients With Gastric Cancer

Gastric Cancer, Metastatic
Clinica Alemana de Santiago

Not yet recruiting

Acetazolamide or Metolazone in Acute Heart Failure (ACME-AHF)

Decompensated Heart Failure | Heart Failure Acute
Jiangsu Province Nanjing Brain Hospital

Recruiting

Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets Versus Desvenlafaxine Succinate Sustained-release Tablets Targeting Anhedonia in Patients With Major Depression Disorder

Anhedonia

China
SparX Biotech(Jiangsu) Co., Ltd.

Recruiting

A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors (SPX-303)

Solid Tumor | CRC | HNSCC | RCC

United States
National Cancer Institute (NCI)

Recruiting

Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancer

Endometrial Cancer | Endometrial Carcinoma | Cancer of Endometrium | Carcinoma of Endometrium

United States
Fred Hutchinson Cancer Center
PromiCell Therapeutics, Inc.

Not yet recruiting

Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma

United States
Finn, Olivera, PhD
Breast Cancer Research Foundation; A Glimmer of Hope Foundation

Recruiting

Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In Situ

Ductal Carcinoma in Situ

United States
Wuhan Union Hospital, China
CSPC Pharmaceutical Group Limited

Recruiting

Mitoxantrone Hydrochloride Liposome Injection-containing Bridging Regimen and CD19-targeting CAR-T Therapies

B-cell Acute Lymphoblastic Leukemia | B-cell Lymphoma Refractory

China
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

Targeting ODC as an Immunotherapeutic Target in STK11 (LKB1) Pathway-Deficient NSCLC (DFMO)

Lung Cancer | Non Small Cell Lung Cancer

United States
Neogene Therapeutics, Inc.

Recruiting

A Study of NT-112 in HLA-C*08:02-Positive Adult Subjects With Unresectable, Advanced, and/ or Metastatic Solid Tumors Positive for the KRAS G12D Mutation

Endometrial Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma | Colorectal Carcinoma | Solid Tumor, Adult | KRAS G12D

United States
Beijing Bio-Targeting Therapeutics Technology Co...

Not yet recruiting

A Clinical Study Evaluating the Safety and Efficacy of BioTTT001 in Patients With Malignant Solid Tumors

Solid Tumor

China
Essen Biotech

Not yet recruiting

Fourth-gen CAR T Cells Targeting CD19/CD22 for Highly Resistant B-cell Lymphoma/Leukemia (PMBCL/CNS-BCL). (BAH241)

Lymphoma, Follicular | Diffuse Large B Cell Lymphoma | Acute Lymphoblastic Leukemia, in Relapse | MCL | Central Nervous System Lymphoma | Acute Lymphoblastic Leukemia, Adult B-Cell | Non-Hodgkin Lymphoma, B-cell

China
British Columbia Cancer Agency

Not yet recruiting

CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies

B-cell Lymphoma | Non-Hodgkin's Lymphoma | Mantle Cell Lymphoma | Diffuse Large B Cell Lymphoma | B-Cell Leukemia | B-cell Acute Lymphoblastic Leukemia | Primary Mediastinal Large B-cell Lymphoma (PMBCL) | High-grade B-cell Lymphoma

Canada
Pfizer
Arvinas Estrogen Receptor, Inc.

Recruiting

A Study to Learn About Vepdegestrant When Given With PF-07220060 to People With Advanced or Metastatic Breast Cancer.

Breast Cancer

United States, Japan, Puerto Rico
Siriraj Hospital

Recruiting

The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial

Critical Illness | Respiratory Failure | Lung Injury | Respiratory Distress Syndrome, Adult | Mechanical Ventilation Complication

Thailand
Children's Hospital of Fudan University
Adfontes (Shanghai) Bio-technology Co.,Ltd.

Recruiting

Intervention for Children With Type 1 Diabetes Targeting Gut Microbes (TRIM1)

Type 1 Diabetes

China
Mayo Clinic

Recruiting

B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies

Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | B-Cell Non-Hodgkin Lymphoma | Recurrent Small Lymphocytic Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Chronic Lymphocytic Leukemia | Refractory Mantle Cell Lymphoma | Recurrent... and other conditions

United States
The First Affiliated Hospital of Xiamen University

Recruiting

ImmunoPET Targeting Trophoblast Cell-surface Antigen 2 (Trop-2) in Solid Tumors

Solid Tumor | Tumor | Positron-Emission Tomography

China
Guangdong Provincial People's Hospital
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Recruiting

A Novel 68Ga Labeled FAP Ligand PET/CT in Patients With Various Malignant Tumors (68Ga-GPFAPI)

Cancer | Metastatic Cancer | Malignant Neoplasm | Tumors

China
IRCCS National Neurological Institute "C. Mondino...

Recruiting

HD-EEG Connectivity Changes in Migraine Patients Undergoing Treatment With Anti-CGRP mAbs

Migraine Disorders | Chronic Migraine | Episodic Migraine

Italy
Juno Therapeutics, Inc., a Bristol-Myers Squibb...

Recruiting

A Study to Assess BMS-986453 in Participants With Relapsed and/or Refractory Multiple Myeloma

Relapsed and/or Refractory Multiple Myeloma

United States, France, Spain, Germany
Chulalongkorn University
King Chulalongkorn Memorial Hospital; Health Systems Research Institute

Recruiting

Safety of PiggyBac Transposon CAR T-cells Targeting CD-19 in Refractory Lupus.

SLE (Systemic Lupus)

Thailand
ModernaTX, Inc.

Recruiting

A Study of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus in Pregnant Women and in Infants Born to Vaccinated Mothers

Respiratory Syncytial Virus

Canada, United Kingdom, Japan, United States, Chile, Denmark, Panama, South Africa
Charlotte Lemech
The University of New South Wales

Not yet recruiting

Immunotherapy Targeting of Cytomegalovirus Antigens in Glioblastoma

Glioblastoma
Guangzhou JOYO Pharma Co., Ltd

Recruiting

Study of Oral JYP0322 in Patients With Locally Advanced or Metastatic Cancer Targeting ROS1 Molecular Fusion.

Lung Neoplasms | Brain Neoplasms | Protein Kinase Inhibitors | Other Protocol Specified Criteria

China
Chongqing Precision Biotech Co., Ltd
First Affiliated Hospital of Wannan Medical College

Recruiting

Clinical Study of CEA Targeting Chimeric Antigen Receptor T Lymphocytes（CAR-T） for CEA Positive Advanced Malignant Solid Tumors

Breast Cancer | Gastric Cancer | Lung Cancer | Rectal Cancer | Cholangiocarcinoma | Colon Cancer | Pancreas Cancer | Esophagus Cancer

China
Harvard School of Public Health (HSPH)
Addis Continental Institute of Public Health; George Mason University

Recruiting

BEP Targeting Strategies in Ethiopia (BEP)

Preterm Birth | Birth Weight | Perinatal Death | Gestational Weight Gain | Stillbirth | Neonatal Death | Small for Gestational Age at Delivery | Maternal Anemia in Pregnancy, Before Birth

Ethiopia
UNC Lineberger Comprehensive Cancer Center
Bellicum Pharmaceuticals; University Cancer Research Fund at Lineberger Comprehensive...

Recruiting

Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC

Head and Neck Cancer | Relapse | Refractory Cancer | Recurrent

United States
OncoResponse, Inc.

Recruiting

A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents

Cancer | Metastatic Cancer | Advanced Solid Tumor | Platinum-resistant Ovarian Cancer | Malignant Neoplasm | Tumor, Solid | Cutaneous Squamous Cell Carcinoma

United States

Search clinical trials for: Drug Targeting

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