Search clinical trials for: Early Antiviral Therapy

Total 69730 results

New York Medical College

Recruiting

Chemoradiotherapy With Targeted Immunotherapy in Pediatric Lymphoma (RADICAL)

Hodgkin Lymphoma | Non-hodgkin Lymphoma

United States
University of Oxford

Recruiting

Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV) (PLATCOV)

COVID-19

Lao People's Democratic Republic, Thailand, Brazil, Pakistan
National Cancer Institute (NCI)

Recruiting

Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung Cancer

Lung Non-Small Cell Carcinoma | Stage II Lung Cancer AJCC v8 | Stage I Lung Cancer AJCC v8

United States
CCTU- Cancer Theme
AstraZeneca

Recruiting

AZD6738 & Gemcitabine as Combination Therapy (ATRiUM)

Cancer

United Kingdom
Johns Hopkins University
Patient-Centered Outcomes Research Institute; National Multiple Sclerosis Society

Recruiting

Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial (TREAT-MS)

Multiple Sclerosis, Relapsing-Remitting

United States
Hospital JP Garrahan
Hospital Pereyra Rosell, Montevideo, Uruguay

Recruiting

Pediatric Hodgkin Lymphoma Treatment Trial With Low Cumulative Doses of Chemotherapy Agents and Reduced Radiation. (LHGALOP2017)

Pediatric Hodgkin's Disease

Argentina
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

FDG PET/CT in Monitoring Very Early Therapy Response in Patients With Glioblastoma

Glioblastoma

United States
National Cancer Institute (NCI)
NRG Oncology

Suspended

De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer

Oropharyngeal Squamous Cell Carcinoma | Squamous Cell Carcinoma | Basaloid Squamous Cell Carcinoma | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Papillary Squamous Cell Carcinoma | Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC... and other conditions

United States, Canada
Advancing Clinical Therapeutics Globally for HIV...
National Institute of Allergy and Infectious Diseases (NIAID)

Active, not recruiting

Early ART to Limit Infection and Establishment of Reservoir (EARLIER)

HIV-1 Infection

United States, Brazil, Malawi, Zimbabwe, Thailand, Peru
University of Minnesota
National Health and Medical Research Council, Australia; Bristol-Myers Squibb; National Institutes of Health Clinical Center (CC) and other collaborators

Completed

Strategic Timing of Antiretroviral Treatment (START)

HIV Infection

Spain, United States, United Kingdom, Ireland, Australia, Argentina, Denmark, Sweden, Israel, Switzerland, Germany, Brazil, Norway, Chile, Thailand, Peru, Portugal, Greece, Luxembourg, Uganda, Austria, Belgium, Czechia, Estonia, Finland, ... and more
National Institute of Allergy and Infectious Diseases...
Eli Lilly and Company; National Heart, Lung, and Blood Institute (NHLBI); University... and other collaborators

Completed

LY3819253 (LY-CoV555) for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)

COVID-19

United States, Denmark, Singapore, Spain
Harvard School of Public Health (HSPH)
University of California, San Diego; Brigham and Women's Hospital; Ragon Institute...

Active, not recruiting

Early Infant HIV Treatment in Botswana (EIT)

HIV | Pediatric AIDS

Botswana
Imperial College London
Medical Research Council; University of Oxford; Guy's and St Thomas' NHS Foundation... and other collaborators

Completed

Research In Viral Eradication of HIV Reservoirs (RIVER)

HIV

United Kingdom
Johns Hopkins Bloomberg School of Public Health
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Anti-HIV Medications for People Recently Infected With HIV

HIV Infections

United States, Canada
Roswell Park Cancer Institute
National Center for Advancing Translational Sciences (NCATS)

Completed

Chemokine Modulation Therapy and Standard Chemotherapy Before Surgery for the Treatment of Early Stage Triple Negative Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Prognostic Stage I Breast Cancer AJCC v8 | Prognostic... and other conditions

United States
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
Bess Frost, PhD
Owens Medical Research Foundation

Active, not recruiting

Pilot Study to Investigate the Safety and Feasibility of AntiRetroviral Therapy for Alzheimer's Disease (ART-AD)

Alzheimer Disease, Early Onset

United States
H. Lee Moffitt Cancer Center and Research Institute
Horizon Pharma Ireland, Ltd., Dublin Ireland

Completed

Phase I-II Study of Interferon-gamma in Patients With HER-2 Positive Breast Cancer

Breast Cancer | Breast Cancer, Male | HER2-positive Breast Cancer | Breast Cancer Female

United States
West German Study Group
Celgene

Active, not recruiting

Adjuvant Dynamic Marker-Adjusted Personalized Therapy Trial Optimizing Risk Assessment and Therapy Response Prediction in Early Breast Cancer - Triple Negative Breast Cancer (ADAPT)

Breast Cancer

Germany
Coordinación de Investigación en Salud, Mexico
University College, London; Centro de Investigacion y Estudios Avanzados del... and other collaborators

Completed

Favipiravir +/- Nitazoxanide: Early Antivirals Combination Therapy in COVID-19 (FANTAZE)

Covid19

Mexico
National Institute of Allergy and Infectious Diseases...

Completed

Clinical Outcomes of People Who Acquired HIV in Early Life

HIV

United States
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France

Completed

National Multicenter Trial Evaluating Two Treatments in Patients With Primary Human Immunodeficiency Virus (HIV-1) Infection (OPTIPRIM-2)

HIV-1 Infection

France
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Virologic Effect of a Human Monoclonal Antibody (VRC01) Administered Intravenously to Adults During Early Acute HIV Infection

HIV Infections

Uganda, Kenya, Tanzania, Thailand
National Institute of Allergy and Infectious Diseases...
Chiron Corporation

Completed

An International Study to Evaluate Recombinant Interleukin-2 in HIV Positive Patients Taking Anti-retroviral Therapy (ESPRIT)

HIV Infections

United States, Brazil, Australia, Argentina, Austria, Belgium, Canada, Denmark, France, Germany, Ireland, Israel, Italy, Japan, Morocco, Netherlands, Norway, Poland, Portugal, Singapore, Spain, Sweden, Switzerland, Thailand, United Kingdom
National Institute of Allergy and Infectious Diseases...

Withdrawn

Safety and Effectiveness of an Anti-HIV Drug Combination With and Without Hydroxyurea in Patients With Early HIV Infection

HIV Infections
National Institute of Allergy and Infectious Diseases...

Withdrawn

Effectiveness of Early or Delayed Addition of Hydroxyurea to a Three-Drug Anti-HIV Drug Combination Including Didanosine, in Advanced HIV Patients Who Failed a First or Second Anti-HIV Triple-Drug Therapy

HIV Infections
National Institute of Allergy and Infectious Diseases...

Completed

A Randomized Trial of the Efficacy and Safety of a Strategy of Starting With Nelfinavir Versus Ritonavir Added to Background Antiretroviral (AR) Nucleoside Therapy in HIV-Infected Individuals With CD4+ Cell Counts Less Than or Equal to 200/mm3

HIV Infections

United States, Canada
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

A Study to Compare Two Different Anti-HIV Drug Regimens

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Multicenter Phase II Double-Blind Exploratory Study to Evaluate Differences Among Various Zidovudine/Didanosine Regimens on Quantitative Measures of Viral Burden in Relatively Early HIV-1 Infection

HIV Infections

United States
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

MRD/Risk-oriented Therapy of Adult Ph- ALL Including Pegylated Asparaginase and Lineage-targeted Methotrexate (LAL1913)

Secondary | De Novo | Untreated Philadelphia Positive Acute Lymphoblastic Leukemia | Low-dose Corticosteroids Pretreatment

Italy
Columbia University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Latency and Early Neonatal Provision of Antiretroviral Drugs Clinical Trial (LEOPARD)

HIV

South Africa
University of Zurich

Unknown

Early Simplified: A Trial to Compare the Efficacy of Standard of Care Combination Antiretroviral Therapy With a Simplified Dolutegravir Monotherapy in Patients With a Primary HIV-1 Infection

Treatment Efficacy | Monotherapy | Dolutegravir | Primary HIV Infection

Switzerland
Kirby Institute

Completed

DAA-based Therapy for Recently Acquired Hepatitis C II (DAA = Directly Acting Antiviral) (DARE-C II)

Hepatitis C

Australia, New Zealand
Renmin Hospital of Wuhan University

Unknown

Effect of Early Antiviral Therapy on Duration of Cough in Flu Patients

Influenza Virus Infection

China
Nanfang Hospital of Southern Medical University

Unknown

Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult ETP-ALL

Leukemia, Acute | Leukemia, Lymphoblastic | Leukemia, T Cell

China
Sun Yat-sen University

Terminated

Efficacy and Safety Study of P-Gemox vs.EPOCH as First-line Chemotherapy to Treat NK/T-cell Lymphoma With Early Stage

Lymphoma, Extranodal NK-T-Cell

China
Yongtao Sun, MD, PhD
China Medical University, China; Beijing YouAn Hospital; Zhejiang University; Tang-Du... and other collaborators

Unknown

Early cART and cART in Combination With Autologous HIV-1 Specific Cytotoxic T Lymphocyte (CTL) Infusion in The Treatment of Acute HIV-1 Infected Adults

Acute HIV Infection

China
Hospital Nossa Senhora da Conceicao

Completed

Early Antiviral Therapy for Critically Ill HIV Infected Patients

HIV Infection

Brazil
CHU de Quebec-Universite Laval
Johns Hopkins University; Gilead Sciences; Imperial College London; Bill and Melinda... and other collaborators

Completed

Early Antiretroviral Therapy and Pre-exposure Prophylaxis for HIV Prevention Among Female Sex Workers in Cotonou, Benin (TasP/PrEP)

Adherence to Medication Regime

Benin
Global Emerging Infections Surveillance and Response...
Walter Reed Army Institute of Research (WRAIR); United States Army Medical...

Completed

In Vivo and In Vitro Efficacy of Artemisinin Combination Therapy

Malaria

Kenya
Heidelberg University
Verein für Krebsforschung, Arlesheim, Swizzerland; Weleda AG, D-73525 Schwäbisch...

Completed

Mistletoe Extract in Early or Advanced Breast Cancer, A Feasibility Study

Metastatic Breast Cancer

Germany
Ain Shams University

Completed

Early Treatment of Recurrent HCV- Infection Post Liver Transplantation in the Era of DAAs

Liver Transplantation
University of North Carolina, Chapel Hill
National Institute on Drug Abuse (NIDA); National Institute of Mental Health... and other collaborators

Completed

Preservation and Expansion of T-cell Subsets Following HAART De-intensification to Atazanavir/Ritonavir (ATV/r)

HIV Infections

United States, Puerto Rico
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Terminated

Chemotherapy or Observation in Treating Patients With Early Stage Non-Small Cell Lung Cancer

Lung Cancer

United States, Australia
David A Wohl, MD
Merck Sharp & Dohme LLC

Completed

Raltegravir as Early Therapy in African-Americans Living With HIV Study (REAL)

HIV Infections

United States
David Garcia Cinca
Fundacion Clinic per a la Recerca Biomédica

Unknown

Impact of Extremely Early Antiretroviral Therapy to Reduce VIral REservoir and Induce Functional CURE of HIV-1 Infection (VIRECURE)

HIV Infections

Spain
University of Zimbabwe
AIDS Care Research in Africa

Completed

Early Versus Delayed Antiretroviral Therapy (ART) in the Treatment of Cryptococcal Meningitis in Africa

HIV Infections | Cryptococcal Meningitis

Zimbabwe
Merck Sharp & Dohme LLC

Approved for marketing

Early Access of MK0518 in Combination With an Optimized Background Antiretroviral Therapy (0518-023)

HIV Infections
Anna Griffiths, MRC
Medical Research Council; Wellcome Trust; Department for International Development... and other collaborators

Completed

Reduction of EArly mortaLITY in HIV-infected Adults and Children Starting Antiretroviral Therapy (REALITY)

Human Immunodeficiency Virus

Malawi, Zimbabwe, Kenya, Uganda
University of California, San Francisco
Makerere University; Infectious Diseases Research Collaboration, Uganda; Makerere...

Completed

Early HIV Therapy in Patients With High CD4 Cell Counts (EARLI)

HIV

Uganda

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