Search clinical trials for: GCM

Total 111 results

Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

Taiwan, United States, Spain, Argentina, China, Italy, Australia, France, Canada, Japan, Belgium, Denmark, Germany, Hungary, Israel, Austria, Korea, Republic of, Brazil, Mexico, Netherlands, Romania, United Kingdom, Greece, Czechia, India, Slovak... and more
Eli Lilly and Company

Recruiting

Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)

Diabetes Mellitus, Type 2

United States, Canada, Mexico, Argentina, Puerto Rico
University Hospital, Ghent

Recruiting

Characteristics of (Unwanted) Use of Alcohol and Illicit Substances Among Patients Reporting After Sexual Violence in Ghent: a Mono-centric Prospective Observational Study

Drug-facilitated Sexual Assault

Belgium
AbbVie

Recruiting

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata (Up-AA)

Alopecia Areata

United States, Australia, Japan, Puerto Rico, New Zealand, China, Canada, Brazil, United Kingdom, Korea, Republic of, Chile
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome (POETYK SjS-1)

Sjögren's Syndrome

United States, Australia, Germany, Korea, Republic of, Austria, China, Japan, Puerto Rico, Poland, Canada, Hungary, Spain, Argentina, Chile, Denmark, France, Italy, Mexico, Peru, Netherlands, Belgium, Brazil, Colombia, United Kingdom, P... and more
AbbVie

Recruiting

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus (SELECT-SLE)

Systemic Lupus Erythematosus

United States, Japan, Puerto Rico, Switzerland, Israel, Korea, Republic of, Hungary, New Zealand, Bulgaria, Latvia, Taiwan, Slovakia, Croatia, South Africa, Australia, Poland, Portugal, Spain, Estonia, France, Lithuania, Brazil, Ger... and more
AbbVie

Recruiting

Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis (SELECT- SWITCH)

Rheumatoid Arthritis

United States, Japan, United Kingdom, Canada, Korea, Republic of, Puerto Rico, South Africa, Hungary, Bulgaria, Spain, Portugal, Chile, Croatia, France, Belgium, Germany, Greece, Romania, Brazil, Italy, Serbia, China, Colombia, Mexico
Eli Lilly and Company

Recruiting

A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk (ACHIEVE-4)

Cardiovascular Diseases | Obesity | Overweight | Type 2 Diabetes | Chronic Kidney Disease | Overweight or Obesity

United States, Italy, Spain, Korea, Republic of, India, Turkey, Austria, Puerto Rico, Mexico, Romania, Brazil, Germany, Argentina, Czechia, Greece, Slovakia
Kezar Life Sciences, Inc.

Recruiting

A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis (PALIZADE)

Lupus Nephritis

United States, Korea, Republic of, Australia, Malaysia, Taiwan, South Africa, China, Singapore, United Kingdom, Puerto Rico, Croatia, India, Greece, Spain, Brazil, Philippines, Guatemala, Argentina, Portugal, Colombia
Amgen

Recruiting

A Study to Evaluate Rocatinlimab (AMG 451) in Adolescent Subjects With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-ASTRO)

Atopic Dermatitis

United States, Korea, Republic of, Taiwan, Spain, Croatia, China, Greece, Belgium, Thailand, Puerto Rico, Hungary, Poland, Germany, Brazil, Italy, Japan, Canada, France, Romania, Chile
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Effect of Deucravacitinib on Quality of Life in Participants With Plaque Psoriasis in a Community Setting (ARTISTYK)

Psoriasis

United States, Puerto Rico
Idorsia Pharmaceuticals Ltd.

Recruiting

A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus (OPUS-2)

Lupus Erythematosus, Systemic

Spain, United States, Georgia, Serbia, Germany, Portugal, Poland, South Africa, Philippines, Czechia, Puerto Rico, Chile, Japan, Peru
Bristol-Myers Squibb

Recruiting

A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE) (POETYK SLE-1)

Systemic Lupus Erythematosus

United States, Brazil, China, Germany, Italy, France, Mexico, Poland, Puerto Rico, Argentina, Canada, Colombia, Hong Kong, Peru, Romania, Portugal, Korea, Republic of, Turkey, Ireland, India, Lithuania, Bulgaria, Slovakia
Biogen

Recruiting

A Study to Assess the Efficacy and Safety of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) and/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Therapy (AMETHYST)

Subacute Cutaneous Lupus Erythematosus | Chronic Cutaneous Lupus Erythematosus

United States, Italy, Korea, Republic of, Taiwan, Argentina, Chile, Spain, Canada, Serbia, France, Germany, Japan, Brazil, United Kingdom, Bulgaria, Portugal, Switzerland, Philippines, Saudi Arabia, Sweden, Mexico, Poland, Hungary, Puerto... and more
AbbVie

Recruiting

Study of Cariprazine Oral Capsules or Solution to Assess Adverse Events and Change in Irritability Due to Autism Spectrum Disorder (ASD) in Participants Aged 5-17 Years With ASD

Autism Spectrum Disorder

United States, Puerto Rico
Vertex Pharmaceuticals Incorporated

Recruiting

Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease Mediated Proteinuric Kidney Disease (AMPLITUDE)

Proteinuric Kidney Disease

United States, Spain, Ghana, France, United Kingdom, Belgium, Brazil, Colombia, Portugal, Canada, Puerto Rico, Netherlands
AbbVie

Recruiting

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

Migraine

United States, Puerto Rico
Sanofi

Recruiting

Efficacy and Safety of SAR441344 in the Treatment of Systemic Lupus Erythematosus (APATURA)

Systemic Lupus Erythematosus

Chile, Brazil, Greece, Italy, Spain, United States, Argentina, Hungary, Mauritius, Mexico, Russian Federation, Turkey, Ukraine, Puerto Rico, Switzerland
Second Affiliated Hospital of Wenzhou Medical University
First Affiliated Hospital of Wenzhou Medical University; Taizhou Hospital of...

Recruiting

Gastric Cancer Marker Detection and Its Kit Development (GCMDKD)

Gastric Cancer

China
VitalAire

Not yet recruiting

Impact of the Use of a Closed-loop Insulin Therapy on the Burden of the Diabetes and the Quality of Life (IMPLIQUE)

Quality of Life | Burden, Dependency
Janssen Research & Development, LLC

Recruiting

Guselkumab in Active Psoriatic Arthritis Participants With Inadequate Response/Intolerance to One Prior Anti-TNF Alpha Agent (SOLSTICE)

Arthritis, Psoriatic

Israel, Turkey, United States, Hungary, Spain, Australia, Bulgaria, Czechia, Malaysia, Poland, Puerto Rico, Russian Federation, Ukraine, Argentina
Bristol-Myers Squibb

Recruiting

A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus

United States, Taiwan, Japan, Brazil, Colombia, Germany, Poland, Puerto Rico, China, Mexico, Argentina, France, Chile, Australia, India, Spain, United Kingdom, Romania, Ireland
AbbVie

Recruiting

A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

Depression | Bipolar I Disorder

United States, Puerto Rico, Russian Federation
AbbVie

Recruiting

Open-Label, Flexible-dose Study to Evaluate the Long-Term Safety and Tolerability of Cariprazine in the Treatment of Pediatric Participants With Schizophrenia, Bipolar I Disorder, or Autism Spectrum Disorder

Schizophrenia | Bipolar I Disorder | Autism Spectrum Disorder (ASD)

United States, Puerto Rico
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Electrophysiology of Fetal Arrhythmia (fMCG)

Fetal Arrhythmia

United States
Actelion

Active, not recruiting

Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH) (A DUE)

Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)

United States, Japan, Taiwan, Turkey, Canada, China, Germany, Spain, Italy, Malaysia, Hungary, Russian Federation, Brazil, Australia, Bulgaria, Czechia, Mexico, Poland, South Africa
AbbVie

Active, not recruiting

A Study to Evaluate Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis (Level Up)

Atopic Dermatitis

United States, Australia, Belgium, Bulgaria, Canada, China, Denmark, France, Germany, Hungary, Italy, Korea, Republic of, Mexico, Netherlands, Poland, Portugal, Puerto Rico, Romania, Slovakia, South Africa, Spain, Sweden, Switzerland, Taiwa... and more
Eli Lilly and Company

Active, not recruiting

A Study of Peresolimab (LY3462817) in Participants With Moderately-to-Severely Active Rheumatoid Arthritis (RESOLUTION-1)

Immune System Diseases | Autoimmune Diseases | Arthritis | Joint Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Connective Tissue Diseases | Rheumatoid Arthritis

United States, Spain, China, Mexico, Puerto Rico, Japan, Canada, Argentina, Poland, Hungary, Greece
AbbVie

Active, not recruiting

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Upadacitinib in Pediatric Subjects With Polyarticular Course Juvenile Idiopathic Arthritis (SELECT-YOUTH)

Juvenile Idiopathic Arthritis (JIA)

United States, Canada, Germany, Hungary, Israel, Italy, Japan, Puerto Rico, Spain, Sweden
Amgen

Completed

An Efficacy and Safety Study of Apremilast (CC-10004) in Subjects With Moderate to Severe Genital Psoriasis (DISCREET)

Psoriasis

United States, Belgium, Italy, France, Germany, Puerto Rico, Canada
Pfizer

Completed

Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA) (MIRNA)

Nonalcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis With Liver Fibrosis

Hong Kong, United States, Taiwan, Puerto Rico, China, Canada, Korea, Republic of, Bulgaria, Japan, India, Poland, Slovakia
Eli Lilly and Company

Active, not recruiting

A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes (SURPASS-CVOT)

Type 2 Diabetes Mellitus

China, United States, Netherlands, Spain, Australia, Austria, India, Canada, Taiwan, United Kingdom, Belgium, France, Germany, Mexico, Romania, Italy, Argentina, Brazil, Puerto Rico, Ukraine, Hungary, Japan, Czechia, Turkey, Korea, Republic... and more
Nektar Therapeutics
Eli Lilly and Company

Completed

A Study of LY3471851 in Adults With Systemic Lupus Erythematosus (SLE) (ISLAND-SLE)

Systemic Lupus Erythematosus

United States, Spain, Japan, India, Israel, Korea, Republic of, Taiwan, Australia, Puerto Rico, Argentina, Romania, Canada, Germany, Russian Federation, Mexico, Ukraine, Poland, Czechia, Hungary
Eli Lilly and Company
Incyte Corporation

Active, not recruiting

A Study of Baricitinib (LY3009104) in Participants With Severe or Very Severe Alopecia Areata (BRAVE-AA1)

Alopecia Areata

United States, Puerto Rico, Japan, Mexico, Korea, Republic of
Eli Lilly and Company

Active, not recruiting

A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity (SURMOUNT-MMO)

Obesity | Overweight

Spain, United States, Australia, Italy, Hungary, India, Israel, Canada, China, Taiwan, United Kingdom, Belgium, France, Germany, Mexico, Romania, Poland, Argentina, Brazil, Puerto Rico, Austria, Turkey, Japan, Netherlands, Korea, Republic... and more
Eli Lilly and Company

Active, not recruiting

A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight (SURMOUNT-1)

Obesity | Overweight

United States, Taiwan, India, China, Mexico, Brazil, Puerto Rico, Japan, Argentina, Russian Federation
Eli Lilly and Company

Active, not recruiting

A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 2 Diabetes Currently Treated With Basal Insulin

Type 2 Diabetes

United States, Spain, Taiwan, Japan, Poland, Argentina, Hungary, Puerto Rico, Korea, Republic of, Slovakia
Eli Lilly and Company
Incyte Corporation

Active, not recruiting

A Study of Baricitinib (LY3009104) in Participants With Rheumatoid Arthritis (RA-BRIDGE)

Rheumatoid Arthritis

Spain, United States, Hungary, Australia, Turkey, Czechia, Belgium, United Kingdom, Poland, Puerto Rico, Israel, Switzerland, France, South Africa, Romania, Italy, Germany, Netherlands, Austria, Denmark, Lithuania, Russian Federation and more
Eli Lilly and Company

Active, not recruiting

A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes (SURPASS-EARLY)

Type 2 Diabetes

United States, United Kingdom, Germany, Mexico, Romania, Argentina, Canada, Puerto Rico, Israel, Italy, Slovakia
Eli Lilly and Company

Active, not recruiting

A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-1)

Obesity | Overweight | Overweight or Obesity

United States, China, India, Taiwan, Japan, Brazil, Puerto Rico, Spain, Slovakia, Korea, Republic of
AbbVie

Enrolling by invitation

A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis (AD Up)

Atopic Dermatitis

United States, Australia, Austria, Belgium, Canada, China, Czechia, France, Germany, Greece, Hong Kong, Hungary, Ireland, Israel, Italy, Japan, Netherlands, New Zealand, Norway, Puerto Rico, Slovakia, Spain, Sweden, United Kingdom
Rigshospitalet, Denmark

Withdrawn

The Impact of Different Simulator Characteristics on Transfer of Learning

Education, Professional | Ultrasound Simulation | Simulation-based Medical Education
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight (SURMOUNT-2)

Obesity | Overweight | Type 2 Diabetes

United States, Russian Federation, Taiwan, Argentina, Brazil, Japan, Puerto Rico, India
Indigo Diabetes NV

Completed

The SHINE Study: Safety of Implant and Preliminary Performance of the SHINE SYSTEM in Diabetic Subjects

Diabetes Mellitus, Type 2 | Diabetes Mellitus | Hypoglycemia | Diabetes Mellitus, Type 1 | Ketoacidosis, Diabetic | Hyperglycaemia (Diabetic)

Belgium, Slovenia, France
AbbVie
Endo Pharmaceuticals; Allergan Sales, LLC; Acerus Pharmaceuticals Corporation; Upsher-Smith...

Completed

A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men (TRAVERSE)

Cardiovascular Diseases | Hypogonadism

United States, Puerto Rico
Eli Lilly and Company

Completed

A IMMA Master Protocol: A Study of LY3361237 in Participants With at Least Moderately Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States, Puerto Rico, Czechia, Taiwan, Argentina, France, Poland, Mexico
Pfizer

Terminated

Trial to Learn About the Study Medicine (PF-07081532) and Rybelsus in People With Type 2 Diabetes and Separately PF-07081532 in People With Obesity

Obesity | Diabetes Mellitus

United States, Hungary, Canada, Japan, Poland, Puerto Rico, Bulgaria, Czechia
AbbVie

Completed

A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants With Moderately to Severely Active Systemic Lupus Erythematosus to Assess Change in Disease State

Systemic Lupus Erythematosus (SLE)

United States, Argentina, Australia, Bulgaria, China, Colombia, Germany, Hungary, Italy, Japan, Korea, Republic of, Mexico, New Zealand, Poland, Puerto Rico, Spain, Taiwan, United Kingdom
Bristol-Myers Squibb

Active, not recruiting

A Study of Nivolumab and Ipilimumab in Untreated Participants With Stage 3 Non-small Cell Lung Cancer (NSCLC) That is Unable or Not Planned to be Removed by Surgery (CheckMate73L)

Non-Small Cell Lung Cancer (NSCLC)

Russian Federation, United States, Argentina, Australia, Belgium, Brazil, Canada, Chile, China, France, Germany, Greece, Ireland, Italy, Japan, Korea, Republic of, Mexico, Netherlands, Poland, Puerto Rico, Romania, Spain, Sweden, Swit... and more
Universitätsklinikum Hamburg-Eppendorf

Active, not recruiting

Clofarabine or High-Dose Cytarabine and Pegaspargase in Children With ALL

Leukemia

Germany

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