Search clinical trials for: GH/IGF-1 axis

Total 47454 results

Herlev Hospital

Unknown

The Relationship Between the Growth Hormone (GH)- Insulin Like Growth Factor I (IGF-I) System and the Inflammatory System in Healthy Normal Persons

Interaction Between the GH/IGF-I System and the Immune-system

Denmark
Federico II University

Completed

Growth Factor/Insulin-like Growth Factor (GH/IGF)-1 Axis in Obese Subjects in Treatment With Orlistat

Obesity
Rabin Medical Center
Pfizer

Completed

Growth and Metabolic Response to GH and GnRHa Treatment Versus GH Alone in Boys Born SGA.

SGA and Growth

Israel
Maimonides Medical Center

Withdrawn

The Role of Igf-1 Generation Test in Diagnosis and Treatment of Short Stature

Short Stature

United States
Novartis Pharmaceuticals

Completed

An Extension Study to Assess the Long-Term Safety and Efficacy of Pasireotide in Participants With Acromegaly

Acromegaly

Italy, Australia, Belgium, Germany, Switzerland, United States, France
Johann Wolfgang Goethe University Hospital

Unknown

Status of Growth Hormone/ Insulin-like Growth Factor-1 (GH/IGF-1) Axis and Growth Failure in Ataxia Telangiectasia (AT) (GHAT)

Growth Failure | Ataxia Telangiectasia

Germany
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Evaluation the Growth Factors(IGF-1,IGFBP-3and HGH)in Patients With Chronic Liver Disease

Liver Cirrhosis | Hepatitis | Hepatocellular Carcinoma

Taiwan
Ipsen

Terminated

IGF-1, IGFBP3, ALS Normative Ranges in Healthy Pediatric Spanish Population (EDISON)

IGF-1 Deficiency

Spain
Karolinska University Hospital

Completed

Metabolic Effects of GH and IGF-I in Growth Hormone Deficient(GHD) and Diabetes and Impaired Glucose Tolerance(IGT)

Diabetes

Sweden
Columbia University

Not yet recruiting

The AgRP and GH/IGF-1 Axis in Children

Growth Hormone Deficiency
Federico II University

Completed

Prediction of Tumor Shrinkage in Acromegaly

Acromegaly

Italy
University of Aarhus

Completed

Importance of the GH/IGF-1 Axis for Human Substrate and Energy Metabolism During Calorie Restriction

Healthy

Denmark
Federico II University
University of Genova

Completed

Lanreotide Autogel-120 mg as First-Line Treatment of Acromegaly (ATG1line)

Acromegaly

Italy
University Hospital, Rouen

Completed

Somatostatin Analog Treatment of Acromegaly Before Pituitary Surgery : Comparison With Neurosurgery Alone (SAPORO)

Acromegaly

France
Ipsen

Recruiting

Global Patient Registry to Monitor Long-term Safety and Effectiveness of Increlex® in Children and Adolescents With Severe Primary Insulin-like Growth Factor-1 Deficiency (SPIGFD).

IGF1 Deficiency

Spain, United States, Italy, France, United Kingdom, Germany, Austria, French Guiana, Poland, Sweden, Martinique
Penn State University
Massachusetts General Hospital; Purdue University

Completed

Effects of Oral vs. Non-oral Contraceptives on the GH/IGF-1 Axis

Bone; Disorder, Development and Growth

United States
Federico II University

Completed

Effect of 5 Years of GH Replacement on Atherosclerosis (5yrGH)

Growth Hormone Deficiency | Hypopituitarism | Pituitary Tumors

Italy
Postgraduate Institute of Medical Education and...

Unknown

Assessment Of Gh-Igf-1 Axis In Children With Chronic Myelogenous Leukemia (CML) In Remission

Chronic Myelogenous Leukemia | Short Stature

India
Federico II University

Completed

Dose Escalation of Octreotide-LAR as First-Line Therapy in Resistant Acromegaly (HDacro)

Acromegaly

Italy
Novartis Pharmaceuticals

Completed

Efficacy of Octreotide Acetate and Cabergoline in Patients With Acromegaly

Acromegaly

Germany
Vedic Lifesciences Pvt. Ltd.

Recruiting

A Study to Evaluate Efficacy of Different Natural Ingredients in Improving Gut Health in Adults With Leaky Gut.

Gut Health

India
The Christie NHS Foundation Trust

Terminated

Effect of Pegvisomant on GH/IGF-I Relationship in GHD

Severe Adult Growth Hormone Deficiency

United Kingdom
Ipsen

Completed

Recombinant Human Insulin-Like Growth Factor (rhIGF-1) Treatment of Short Stature Associated With IGF-1 Deficiency

Growth Disorders | Insulin-Like Growth Factor-1 Deficiency

United States
University of Aarhus

Active, not recruiting

ACRODAT Prospective Evaluation Study

Acromegaly

Denmark
Tulane University Health Sciences Center

Withdrawn

Effect of Continuous GHRP-3 Infusion at on GH-IGF-I System, Blood Pressure, Glucose, and Insulin Resistance

Insulin Resistance | Endothelial Dysfunction
Federico II University

Completed

Replacement GH Therapy After Bariatric Surgery in Patients With Very Severe Obesity (GH&LASGB)

Obesity | GHD

Italy
Assiut University

Unknown

Effect of Maternal BMI and Type of Infants Feeding on IGF-1 in Infant

IGF1 Deficiency
Karolinska Institutet

Unknown

Basal Analog Study - Comparison of Lantus or Levemir With NPH Insulin From T1DM Diagnosis (BAS)

Diabetes Mellitus Type 1

Sweden
Guangzhou First People's Hospital

Unknown

To Explore the Effect of GH Pretreatment on Clinical Outcomes in Patients With Low Ovarian Reserve

Low Ovarian Reserve | GH
Azidus Brasil

Unknown

Evaluation of Pharmacokinetic and Pharmacodynamic Parameters of Somatropin Produced by Laboratory Blausiegel Indústria e Comércio Ltda., Compared to Saizen® From Laboratory Merck Serono S.A.

Growth Retardation | GH Deficiency (GHD)

Brazil
Rabin Medical Center
Pfizer

Completed

Short Stature Related Distress

Idiopathic Short Stature | Self Image

Israel
Federico II University

Completed

Impact of Somatostatin Analogs vs. Surgery on Glucose Metabolism in Acromegaly (GLUSSA)

Acromegaly

Italy
Federico II University
Ospedali dei Colli

Completed

GH, IGF-I and Somatostatin Analogues in Hepatocellular Carcinoma (SS-HCC)

Advanced Hepatocellular Carcinoma

Italy
Federico II University

Completed

Cardiovascular Outcome After Surgery or Somatostatin Analogues (CVAcro)

Acromegaly

Italy
University of Aarhus

Completed

Effect of NPH Insulin, Insulin Detemir and Insulin Glargine on GH-IGF-IGFBP Axis

Diabetes Mellitus, Type 1

Denmark
Solvay Pharmaceuticals

Completed

Study to Compare the Effect of Hormone Replacement Therapy (HRT) on Breast and Cardiovascular Metabolic Markers in Postmenopausal Women

Menopause

Italy
US Department of Veterans Affairs

Completed

Effect of a High Protein Diet on the 24-hour Profile of Ghrelin, GH (Growth Hormone) and IGF-1 (Insulin-like Growth Factor-1)

Diabetes Mellitus, Type 2

United States
University of Jordan

Completed

Growth Hormone (GH) Deficiency & Insulin Like Growth Factor 1 (IGF-I)/ Insulin Like Growth Factor Binding Protein 3 (IGFBP-3) Ratio

Diagnosis of GHD With IGF-I/IGFBP-3 Ratio
Baskent University

Completed

A New Marker for Early Diagnosis of Pneumoperitoneum-Related Acute Kidney Injury: Insulin-Like Growth Factor-1 (IGF-1)

Pneumoperitoneum | Acute Kidney Injury (Nontraumatic)

Turkey
University of Colorado, Denver
Gilead Sciences; National Institute on Aging (NIA)

Completed

Exercise for Healthy Aging: The Impact of HIV and Aging on Physical Function and the Somatopause

Inflammation | Obesity | HIV | Aging, Biological

United States
Ipsen

Terminated

IGFD Registry: A Patient Registry for Monitoring Long-term Safety and Efficacy of Increlex

Primary Insulin-like Growth Factor-1 Deficiency

United States
Icahn School of Medicine at Mount Sinai
National Institute of Mental Health (NIMH)

Completed

Clinical Trial in 22q13 Deletion Syndrome(Phelan-McDermid Syndrome)

Phelan-McDermid Syndrome | 22q13 Deletion Syndrome

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Evaluation of Somatostatin Receptors and GH Receptor Expression on Bone of Acromegalic Patients (ACRO-BONE) (ACRO-BONE)

Evaluation of the Expression of Somatostatin Receptors and GH Receptor on Bone of Acromegalic Patients

Italy
HomeoTherapy Co., Ltd

Completed

Safety Study of Homeo-GH (Bone Marrow Derived Clonal Mesenchymal Stem Cell) to Treat Acute/Chronic Graft Versus Host Disease (GVHD) (Homeo-GH)

Graft-vs-Host Disease

Korea, Republic of
Wang Xinying

Completed

Using IGF-1 for Nutritional Monitoring

Nutritional Supplement
Odense University Hospital

Completed

Comparable Effects of Lanreotide Autogel and Octreotide LAR on GH, IGF-I Levels and Patient Satisfaction

Acromegaly

Denmark
University of Roma La Sapienza

Completed

IGF-1, Sarcopenia and Mortality: a Cohort Study in Patient With Cognitive Impairment (ISAAC)

Cognitive Impairment | Insulin-like Growth Factor 1

Italy
University of Aarhus
Odense University Hospital; Aarhus University Hospital; Herlev Hospital; Aalborg... and other collaborators

Completed

Treatment of Acromegaly With Somatostatin Analogs: GH vs. IGF-I as Primary Biochemical Target

Acromegaly

Denmark
Guangzhou First People's Hospital

Unknown

To Explore the Effect of GH on Outcomes of IVF and Telomerase Activity of Granulosa Cells in Women With POR

GH | Poor Ovarian Reserve Based on POSEIDON
Ipsen

Terminated

rhGH and rhIGF-1 Combination Therapy in Children With Short Stature Associated With IGF-1 Deficiency

Insulin-like Growth Factor-1 Deficiency

United States

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