Search clinical trials for: HIV ,,KIDNEY TRANSPLANT, BIKTARVY,cALCINEURIN? mTOR

Total 15125 results

Institut de Médecine et d'Epidémiologie Appliquée...
LAMBERT ASSOUMOU/ UNITE 1136 INSERM; Sebastien GALLIEN/Henri Mondor University... and other collaborators

Active, not recruiting

Pharmacokinetics of Calcineurin & mTOR Inhibitors in HIV-1 Infected Kidney Transplant Recipients After Switch to BIC/FTC/TAF (KINETIK)

HIV-infected Patient Kidney Transplant Recipient

France
Institut de Médecine et d'Epidémiologie Appliquée...

Unknown

Initiation of First-line Antiretroviral Treatment With TENOFOVIR ALAFENAMIDE - EMTRICITABINE - BICTEGRAVIR at the First Clinical Contact in France: Trial IMEA 055 - FAST (FAST)

HIV Seropositivity

France
ViiV Healthcare
Janssen, LP

Completed

A Study to Evaluate Efficacy and Safety of Cabotegravir (CAB) Long Acting (LA) Plus (+) Rilpivirine (RPV) LA Versus BIKTARVY® (BIK) in Participants With Human Immunodeficiency Virus (HIV)-1 Who Are Virologically Suppressed (SOLAR)

HIV Infections

United States, Netherlands, Germany, Canada, Australia, Belgium, France, Spain, Ireland, Italy, United Kingdom, Austria, Japan, Switzerland
Charlotte-Paige Rolle, MD
ViiV Healthcare

Completed

Efficacy of Switching to DTG/3TC in Virologically-suppressed Adults Currently on B/F/TAF (DYAD)

HIV I Infection

United States
Tulika Singh, MD
Gilead Sciences

Recruiting

Study to Assess Switching to B/F/TAF in Treatment Experienced People With HIV Who Are at Least 65 Years of Age

HIV-1-infection

United States
Chelsea and Westminster NHS Foundation Trust

Recruiting

The Effect of Biktarvy (B/F/TAF) on Whole-body Insulin Sensitivity, Lipid and Endocrine Profile in Healthy Volunteers

HIV-1-infection

United Kingdom
Montefiore Medical Center

Terminated

Mechanisms and Treatment of Chronic Allograft Injury (CAI) Due to Calcineurin Inhibitor (CNI) Toxicity

Chronic Allograft Injury | Calcineurin Inhibitor Toxicity

United States
Southampton Healthcare, Inc.

Terminated

Testing the Safety and Efficacy of Commercial Drug Biktarvy in Subjects Known to Have the 184 Resistance Mutation to a Component in Biktarvy

HIV-1-infection

United States
Gregory Huhn
Gilead Sciences

Active, not recruiting

Clinical Opportunities and Management to Exploit Biktarvy as Asynchronous Connection Key (COMEBACK) (COMEBACK)

Hiv

United States
University Hospital, Caen

Completed

Bioequivalence of Solid/Crushed/Dissolved Forms of Biktarvy® (SOLUBIC)

Healthy Volunteers

France
Peking Union Medical College Hospital
Gilead Sciences

Active, not recruiting

Biktarvy in Treatment-Naïve Late Presenters With HIV-1 Infection

HIV-1-infection

China
Vancouver Infectious Diseases Centre

Unknown

Switching to a Fixed Dose Combination of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in HIV-1 Infected Marginalized Populations Who Are Virologically Suppressed

Drug Use | Human Immunodeficiency Virus I Infection

Canada
Gilead Sciences

Recruiting

Study of B/F/TAF in Participants Switching From CAB + RPV to B/F/TAF for HIV-1 Infection (EMPOWER)

HIV-1-infection

United States, France, Canada
Lux Biosciences, Inc.

Completed

A Study of LX211 in Clinically Quiescent Non-infectious Intermediate, Anterior and Intermediate, Posterior or Pan-Uveitis (LUMINATE)

Panuveitis | Uveitis, Posterior | Uveitis, Intermediate

United States, United Kingdom, Canada, Germany, Austria, France, India
Lux Biosciences, Inc.

Completed

A Study of LX211 in Active Sight Threatening, Non-infectious Intermediate-, Anterior and Intermediate-, Posterior-, or Pan-Uveitis (LUMINATE)

Panuveitis | Uveitis, Posterior | Uveitis, Intermediate

United States, United Kingdom, Canada, Germany, Austria, France, India
Gilead Sciences

Active, not recruiting

Effectiveness, Safety, Adherence, and Health-related Quality of Life in HIV-1 Infected Adults Receiving Bictegravir/ Emtricitabine/Tenofovir Alafenamide (BIC-STaR)

HIV-1-infection

Canada
Gilead Sciences

Completed

Effectiveness, Safety, Adherence, and Health-related Quality of Life in HIV-1 Infected Adults Receiving Bictegravir/ Emtricitabine/Tenofovir Alafenamide (B/F/TAF) (BIC-STaR)

HIV-1-infection

Israel
Gilead Sciences

Completed

Study to Evaluate Switching From an E/C/F/TAF Fixed-Dose Combination (FDC) Regimen or a TDF Containing Regimen to B/F/TAF FDC in Human Immunodeficiency Virus-1 (HIV-1) Infected Participants Aged ≥ 65 Years

HIV-1 Infection

Spain, United Kingdom, France, Italy, Belgium
Fenway Community Health

Completed

Biktarvy for Non-Occupational Post-Exposure Prophylaxis (nPEP)

HIV Prevention

United States
Chelsea and Westminster NHS Foundation Trust
Gilead Sciences; Imperial College London

Terminated

Efficacy, Tolerability and Acceptability of Biktarvy by TPLWH

Human Immunodeficiency Virus

United Kingdom
Judit Pich Martínez
Gilead Sciences

Completed

A Test and Treat Strategy in New HIV Diagnosis. (Test&Treat)

HIV-1-infection

Spain
Saint Michael's Medical Center
ViiV Healthcare

Active, not recruiting

Switch to DOVATO in Patients Suppressed on Biktarvy (SOUND) (Sound)

Human Immunodeficiency Virus

United States
NEAT ID Foundation
Gilead Sciences; Janssen Pharmaceuticals

Active, not recruiting

The Late Presenter Treatment Optimisation Study (LAPTOP)

HIV/AIDS

Spain, Ireland, France, United Kingdom, Germany, Italy, Belgium
Atea Pharmaceuticals, Inc.

Not yet recruiting

Drug-drug Interaction Study of Biktarvy and Bemnifosbuvir/Ruzasvir

Healthy Volunteer Study

Canada
Professor Saye Khoo MD, FRCP

Unknown

How Does Antiretroviral Therapy Affect Coronary Atherosclerosis: A Serial CT Study (HART CT)

Coronary Artery Disease | Hiv
Anna Cruceta

Recruiting

Bictegravir/FTC/TAF for the Treatment of Primary HIV Infection (BIC-PHI)

HIV Primary Infection

Spain
Lux Biosciences, Inc.

Completed

A Multi-center Study to Assess the Efficacy and Safety of LX211 in Active Non-infectious Anterior Uveitis (LUMINATE)

Uveitis, Anterior | Panuveitis

United Kingdom, Canada, United States, Germany, Austria, France, India
Gilead Sciences
Merck Sharp & Dohme LLC

Active, not recruiting

Study Evaluating the Safety and Efficacy of Islatravir in Combination With Lenacapavir in Virologically Suppressed People With HIV

HIV-1 Infection

United States
Aurinia Pharmaceuticals Inc.

Completed

Voclosporin in Healthy Japanese Volunteers

Volunteers

Philippines
Gilead Sciences

Completed

Study to Evaluate Switching From a Regimen of Two Nucleos(t)Ide Reverse Transcriptase Inhibitors (NRTI) Plus a Third Agent to a Fixed Dose Combination (FDC) of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF), in Virologically-Suppressed, HIV-1 Infected African American Participants (BRAAVE 2020)

HIV-1 Infection

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cyclosporine A to Treat Hypertrophic Cardiomyopathy (HCM)

Cardiomyopathy, Hypertrophic | Heart Hypertrophy

United States
Chelsea and Westminster NHS Foundation Trust
Gilead Sciences; Imperial College London

Completed

Efficacy of BIC/F/TAF Versus Standard of Care in the Treatment of New HIV Infection Diagnoses in the Context of 'Test and Treat' (BIC-T&T)

Human Immunodeficiency Virus

United Kingdom
Brigham and Women's Hospital
Boston Medical Center; Tufts Medical Center

Completed

Effects of Biktarvy on CFR in Stable HIV Patients (BETTER)

HIV

United States
Fundacion Clinic per a la Recerca Biomédica

Active, not recruiting

Safety, Tolerability, and Efficacy of a Dose Reduction Strategy Based on Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed HIV-infected Adults (BETAF-RED)

HIV Infections

Spain
Dr. Bertrand Lebouche

Recruiting

Antiretroviral Speed Access Program (ASAP)

HIV Infection

Canada
Nantes University Hospital

Terminated

Protocol Calcineurin Inhibitor (CNI) Weaning

Function of Renal Transplant

France
Gilead Sciences

Completed

Study to Evaluate Safety, Pharmacokinetics, and Antiviral Activity of Lenacapavir Administered Subcutaneously in Human Immunodeficiency Virus (HIV) -1 Infected Adults

HIV-1 Infection

United States
Emory University

Completed

Antiretroviral Therapy (ART) Persistence in Different Body Compartments in HIV Negative MSM

HIV | ART

United States
Fundacion SEIMC-GESIDA

Active, not recruiting

Phase IV, a Clinical Trial to Assess Safety and Convenience of the Change From DTG/3TC to BIC/FTC/TAF in People With HIV, Good Virological Control and Neuropsychiatric Vulnerabilities (MIND)

HIV Infections

Spain
University of Oslo School of Pharmacy

Completed

Calcineurin Inhibitor-Free Immunosuppression in Renal Transplant Recipients at Low Immunogenic Risk

Renal Transplant Recipients
Aurinia Pharmaceuticals Inc.

Completed

Ocular Tolerability of Voclosporin Ophthalmic Solution Versus Restasis® in Subjects With Dry Eye Disease

Dry Eye

United States
St. Joseph's Healthcare Hamilton

Withdrawn

Effectiveness of Conversion to Sirolimus Versus Calcineurin Inhibitor (CNI) Reduction in Renal Transplant Patients With Prostate Cancer

Prostate Cancer

Canada
University of Nebraska
Genzyme, a Sanofi Company

Completed

Improved Induction and Maintenance Immunosuppression in Kidney Transplantation

End-stage Renal Disease

United States
Assistance Publique - Hôpitaux de Paris

Terminated

Calcineurin Activity in Renal Recipients

Renal Transplant Rejection

France
Vanderbilt University Medical Center
Veloxis Pharmaceuticals

Enrolling by invitation

Early Use of Long-acting Tacrolimus in Lung Transplant Recipients

Lung Transplant; Complications

United States
UDA Centro Nacional Hepato-Bilio-Pancreático
University Hospital, Limoges; Universidad de la Republica; INSERM UMR-S850, Limoges... and other collaborators

Terminated

Study of PD/PK/PG Relationships of Tacrolimus and Cyclosporin in Liver Transplant Patients (3PIGREF)

End Stage Liver Disease | Diabetes | Toxicity | Rejection | Infection | Malignancy

Uruguay
East Carolina University
Janssen Scientific Affairs, LLC

Recruiting

Effect of Biktarvy & Symtuza on microRNAs in HIV and Correlation With Weight Gain

HIV Infections | Obesity

United States
University of Wisconsin, Madison

Completed

Role of Nox2 in CNI-induced Renal Fibrosis (Nox2)

Kidney Disease

United States
National Institute of Allergy and Infectious Diseases...

Completed

Pediatric Kidney Transplant Without Calcineurin Inhibitors

End-Stage Renal Disease

United States
University of Oslo School of Pharmacy

Terminated

Lowering Total Immunosuppressive Load in Renal Transplant Recipients More Than 12 Months Posttransplant

Renal Transplantation

Norway

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