Search clinical trials for: HRR

Total 96 results

Qian Qin
Janssen, LP; UT Southwestern Comprehensive Cancer Center

Not yet recruiting

Niraparib, Abiraterone Acetate and Prednisone for mHSPC With Deleterious Homologous Recombination Repair Alterations (HARMONY)

BRCA1 Gene Mutation | BRCA2 Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | CHEK2 Gene Mutation | FANCA Gene Mutation | RAD51B Gene Mutation | RAD54L Gene Mutation | Metastatic Hormone-sensitive Prostate Cancer (mHSPC) | Deleterious HRR Gene Mutation
Harran University

Recruiting

Effect On Paın And Anxıety Of Stress Ball Use Durıng Sharp Debrıdement

Diabetic Foot Ulcer

Turkey
University of New Mexico

Recruiting

Particulate vs. Non-Particulate Steroid for Sacroiliac Joint Injection

Sacroiliac Joint Dysfunction | Sacro-Iliac Spondylosis

United States
Pamela Munster
National Cancer Institute (NCI)

Recruiting

Olaparib and ASTX727 in BRCA1/2- and Homologous Recombination Deficient (HRD)-Mutated Tumors

BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene Mutation | BRCA Mutation | Checkpoint Kinase 2 Gene Mutation

United States
AstraZeneca

Recruiting

Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents (EvoPAR-PR01)

Metastatic Castration-Sensitive Prostate Cancer

United States, Canada, Spain, United Kingdom, Italy, Australia, Korea, Republic of, Belgium, Germany, Japan, Peru, France, China, India, Taiwan, Thailand, Austria, Brazil, Turkey, Malaysia, Finland, Netherlands, Chile, Hungary, Poland, Sw...
University of New Mexico

Recruiting

Cognitive Strategies for Improving Health Outcomes And Managing Risk Post-Stroke (CHAMPS)

Stroke

United States
Nacuity Pharmaceuticals, Inc.

Recruiting

PK and PD Study of NPI-001 and Cysteamine Bitartrate (INCA)

Cystinosis

Australia
Shanghai Jiao Tong University School of Medicine

Not yet recruiting

Homologous Recombination Repair Pathway Gene Mutation Spectrum in Chinese Breast Cancer Patients

Breast Cancer
Ying Lin

Recruiting

Neoadjuvant Camrelizumab and Fluzoparib and Nab-paclitaxel in Early Breast Cancer With HRR Gene Mutation (IMPARP)

Her-2 Negative Breast Cancer | HRR Gene Mutation

China
University of New Mexico
Johns Hopkins University; University of Nevada, Las Vegas

Recruiting

Resiliency in U.S. Air Force Personnel

Stress | Anxiety | Resilience | Quality

United States
NovoBliss Research Pvt Ltd
Nanobrid Innovations Private Limited

Not yet recruiting

Primary Irritation Patch Test (PIPT) Study Conducted at NovoBliss Research for Shared Panel

Healthy
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Distribution of the Homologous Recombination-related (HRR) Genesmutationsand HRD in Breast Cancer

Breast Cancer | HER2-low Breast Cancer

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
AstraZeneca

Recruiting

The Study of Olaparib in Newly Diagnosed mCRPC Patients With HRR Gene Mutation (PROspect)

Prostate Cancer | Prostate Carcinoma | Metastatic Castration-resistant Prostate Cancer

China
Nuvation Bio Inc.

Recruiting

NUV-868 as Monotherapy and in Combination With Olaparib or Enzalutamide in Adult Patients With Advanced Solid Tumors

Breast Cancer | Pancreatic Cancer | Ovarian Cancer | Prostate Cancer | Breast Carcinoma | Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | Advanced Solid Tumor | Cancer of the Ovary | Pancreas Cancer | Triple-negative Breast Cancer | Cancer of Pancreas | Pancreas Neoplasm | Prostate Neoplasm | Cancer... and other conditions

United States, Australia
University of New Mexico
Minneapolis Veterans Affairs Medical Center; University of Minnesota; The Mind... and other collaborators

Recruiting

Control Network Neuromodulation to Enhance Cognitive Training in Complex Traumatic Brain Injury (CONNECT-TBI)

Traumatic Brain Injury

United States
Hongqian Guo
AstraZeneca; Nanjing Chia-tai Tianqing Pharmaceutical

Recruiting

The Study of Olaparib Combined With Abiraterone and Prednisone in mHSPC Patients With HRR Gene Mutation

Prostate Cancer | Metastatic Prostate Cancer | Prostate Carcinoma

China
University of Turin, Italy

Recruiting

UNITO-001- Study in HRR/PDL1 Positive MPM/NSCLC (UNITO-001)

Lung Cancer | Mesothelioma

Italy
Yonsei University

Not yet recruiting

Pembrolizumab, Olaparib, Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer With HRR Mutation and MSS

Gastric Cancer Stage IV

Korea, Republic of
CAI Hongbing

Recruiting

A Randomized Prospective Trail of HIPEC in Recurrent Ovarian Cancer Patients With HRR Mutation

Ovarian Cancer | Epithelial Ovarian Cancer | Ovarian Cancer, Epithelial | Hyperthermic Intraperitoneal Chemotherapy(HIPEC) | Homologous Recombination Repair Gene Mutation

China
University of New Mexico
National Institutes of Health (NIH); National Institute of General Medical... and other collaborators

Recruiting

Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia. (AphasiatDCS)

Stroke | Aphasia

United States
Merck Sharp & Dohme LLC
AstraZeneca

Recruiting

Efficacy and Safety of Olaparib (MK-7339) in Participants With Previously Treated, Homologous Recombination Repair Mutation (HRRm) or Homologous Recombination Deficiency (HRD) Positive Advanced Cancer (MK-7339-002 / LYNK-002)

Advanced Solid Neoplasms

United States, Argentina, Australia, Canada, Colombia, Denmark, France, Guatemala, Ireland, Israel, Japan, Korea, Republic of, Mexico, Peru, Romania, Russian Federation, Spain, Switzerland, Turkey, United Kingdom, Italy
Guangxi Medical University

Recruiting

HR Versus RFA for HCC in Patients With PHT (HR-HCC/PHT)

Neoplasms, Glandular and Epithelial | Carcinoma, Hepatocellular | Liver Neoplasms

China
AstraZeneca

Active, not recruiting

Study of Durvalumab+Olaparib or Durvalumab After Treatment With Durvalumab and Chemotherapy in Patients With Lung Cancer (ORION) (ORION)

Non-small Cell Lung Cancer NSCLC

United Kingdom, Belgium, United States, Korea, Republic of, Hungary, Japan, Russian Federation, Poland, Ukraine, India, Mexico, Netherlands
Janssen Research & Development, LLC

Active, not recruiting

A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC) (AMPLITUDE)

Metastatic Castration-sensitive Prostate Cancer

United States, Italy, China, Korea, Republic of, Canada, Australia, United Kingdom, Hungary, France, Taiwan, Thailand, Germany, Malaysia, Denmark, Russian Federation, New Zealand, Ukraine, Bulgaria, Israel, Spain, Turkey, Sweden, Cz... and more
University of New Mexico

Withdrawn

Impact of Clinical Pharmacy Services on Medication Cost and Hospitalization Rates in Hemodialysis Patients

End Stage Renal Disease
University of New Mexico
Quercegen Pharmaceuticals; Gatorade Sports and Science Institute

Completed

Effect of Combined Exercise, Heat, and Quercetin Supplementation on Whole Body Stress Response

Heat Acclimation and Thermotolerance

United States
University of New Mexico
National Center for Research Resources (NCRR)

Terminated

Mindful Eating and Living for Obese Women (MEAL)

Obesity
AstraZeneca

Active, not recruiting

To Assess Safety and Efficacy of Agents Targeting DNA Damage Repair With Olaparib Versus Olaparib Monotherapy.

Metastatic Triple Negative Breast Cancer

United States, Belgium, Italy, Spain, United Kingdom, Canada, Czechia, Poland, France, Korea, Republic of, Germany, Taiwan, Portugal, Netherlands, Ireland
Izzet Celegen

Completed

Inflammation Markers in Hyperemesis Gravidarum

Hyperemesis Gravidarum

Turkey
UNICANCER
ARCAGY/ GINECO GROUP; SOLTI Breast Cancer Research Group

Active, not recruiting

Durvalumab, With Olaparib and Fulvestrant in Advanced ER+, HER2- Breast Cancer Patients. (DOLAF)

ER-positive and HER2-negative Metastatic or Locally Advanced Breast Cancer | a Germline or Somatic BRCA Mutation, or a Deleterious Alteration of Other Genes Involved in Homologous Recombination Repair (HRR) or in MSI Status

France
University of New Mexico
National Center for Research Resources (NCRR)

Completed

Microalbuminuria in Children With and Without Diabetes

Diabetes Mellitus

United States
University of New Mexico

Completed

Detection of Pseudomonas Aeruginosa in the Airways of Patients With CF

Cystic Fibrosis

United States
University of New Mexico

Withdrawn

Identification of Risk Allels for Prostate Cancer

Prostate Cancer

United States
University of New Mexico

Withdrawn

Investigation of Protein Biomarkers of Prostate Cancer

Prostate Cancer

United States
University of New Mexico

Withdrawn

Libman-Sacks Endocarditis as a Cause of Neuropsychiatric Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
University of New Mexico

Completed

Metformin Compared to Glyburide in Gestational Diabetes

Gestational Diabetes

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Olaparib (MK-7339) in Combination With Pembrolizumab (MK-3475) in the Treatment of Homologous Recombination Repair Mutation (HRRm) and/or Homologous Recombination Deficiency (HRD)-Positive Advanced Cancer (MK-7339-007/KEYLYNK-007)

Solid Tumors

Poland, Korea, Republic of, United States, Argentina, Australia, Canada, Colombia, France, Germany, Guatemala, Israel, Italy, Japan, Latvia, Mexico, Peru, Puerto Rico, Romania, South Africa, Spain, Sweden, Turkey, Ukraine
AstraZeneca
Merck Sharp & Dohme LLC; Myriad Genetics, Inc.; Foundation Medicine, Inc.

Completed

Study of Olaparib (Lynparza™) Versus Enzalutamide or Abiraterone Acetate in Men With Metastatic Castration-Resistant Prostate Cancer (PROfound Study)

Metastatic Castration-resistant Prostate Cancer

United States, Canada, Denmark, Germany, Italy, Netherlands, Norway, Spain, Argentina, Taiwan, France, Korea, Republic of, Brazil, Japan, Turkey, United Kingdom, Austria, Australia, Israel, Sweden
University of New Mexico
National Institutes of Health (NIH); National Institute of General Medical...

Completed

Transcranial Direct Current Stimulation for the Treatment of Deficits After Traumatic Brain Injury

Depression | Traumatic Brain Injury | Executive Dysfunction | Post Concussive Symptoms

United States
pharmaand GmbH

Terminated

A Study to Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes (LODESTAR)

Solid Tumor

United States
USDA Grand Forks Human Nutrition Research Center

Completed

How Exercise Signals Health Responses

Overweight

United States
AstraZeneca

Completed

Determination of Prevalence and Features of HRRm mCRPC (ADAM) (ADAM)

HRRm mCRPC

Russian Federation
University of New Mexico

Withdrawn

Safety of Acamprosate for Alcohol Dependence in the Elderly: An Open-Label Study (SAFADIE) (SAFADIE)

Alcohol Dependence

United States
University of New Mexico

Withdrawn

Evaluation of Sildenafil for the Treatment of Moderate Congestive Heart Failure

Heart Failure

United States
University of New Mexico

Completed

Improving Air Force Resilience

Health Promotion | Military Personnel

United States
AstraZeneca

Completed

HRR Prevalence in LatAm PROSPECT Study (PROSPECT)

Castration-resistant Prostate Cancer

Brazil, Peru, Mexico, Argentina, Costa Rica, Colombia, Panama
Idience Co., Ltd.

Active, not recruiting

Basket Trial of IDX-1197, a PARP Inhibitor, in Patients With HRR Mutated Solid Tumors (VASTUS) (VASTUS)

Solid Tumors | Homologous Recombination Deficiency | Homologous Recombination Repair Gene Mutation

Korea, Republic of
University of Helsinki

Completed

Connection Between Periodontitis and Exudative Age-related Macular Degeneration (FLAREPARO)

Periodontitis

Finland
Tianjin Eye Hospital

Completed

HRR as a Novel Biomarker in Sjögren's Syndrome

Sjögren's Syndrome

China
Biosplice Therapeutics, Inc.

Active, not recruiting

A Study Evaluating the Safety and Pharmacokinetics of Orally Administered SM08502 in Subjects With Advanced Solid Tumors

Solid Tumor, Adult

United States

Search clinical trials for: HRR

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Myanmar

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations